Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_G23
(459 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99KI0|ACON_MOUSE Aconitate hydratase, mitochondrial pre... 167 8e-42
sp|Q9ER34|ACON_RAT Aconitate hydratase, mitochondrial precu... 167 1e-41
sp|P20004|ACON_BOVIN Aconitate hydratase, mitochondrial pre... 166 2e-41
sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial pre... 165 4e-41
sp|P16276|ACON_PIG Aconitate hydratase, mitochondrial precu... 165 5e-41
sp|P34455|ACON_CAEEL Probable aconitate hydratase, mitochon... 164 7e-41
sp|P49609|ACON_GRAVE Aconitate hydratase, mitochondrial pre... 145 5e-35
sp|O13966|ACON_SCHPO Aconitate hydratase, mitochondrial pre... 137 9e-33
sp|P19414|ACON_YEAST Aconitate hydratase, mitochondrial pre... 137 1e-32
sp|P39533|ACON2_YEAST Putative aconitase in PRP21-UBP12 int... 111 9e-25
>sp|Q99KI0|ACON_MOUSE Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 780
Score = 167 bits (424), Expect = 8e-42
Identities = 77/107 (71%), Positives = 90/107 (84%)
Frame = +3
Query: 9 REHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLNLA 188
REHAALEPRHLGGR II KSFARIHETNLKKQG+LPLTF+ P DYNKI P DK+++ L
Sbjct: 671 REHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPSDYNKIHPVDKLTIQGLK 730
Query: 189 KFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMRE 329
FAP KP++C IKH +G +E I LNHTFN+ QI+WF+AGSALNRM+E
Sbjct: 731 DFAPGKPLKCVIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>sp|Q9ER34|ACON_RAT Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 780
Score = 167 bits (422), Expect = 1e-41
Identities = 77/107 (71%), Positives = 89/107 (83%)
Frame = +3
Query: 9 REHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLNLA 188
REHAALEPRHLGGR II KSFARIHETNLKKQG+LPLTF+ P DYNKI P DK+++ L
Sbjct: 671 REHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPSDYNKIHPVDKLTIQGLK 730
Query: 189 KFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMRE 329
FAP KP+ C IKH +G +E I LNHTFN+ QI+WF+AGSALNRM+E
Sbjct: 731 DFAPGKPLNCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>sp|P20004|ACON_BOVIN Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 780
Score = 166 bits (420), Expect = 2e-41
Identities = 77/107 (71%), Positives = 89/107 (83%)
Frame = +3
Query: 9 REHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLNLA 188
REHAALEPRHLGGR II KSFARIHETNLKKQG+LPLTF+ P DYNKI P DK+++ L
Sbjct: 671 REHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIKGLK 730
Query: 189 KFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMRE 329
FAP KP+ C IKH +G +E I LNHTFN+ QI+WF+AGSALNRM+E
Sbjct: 731 DFAPGKPLTCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 780
Score = 165 bits (418), Expect = 4e-41
Identities = 76/107 (71%), Positives = 89/107 (83%)
Frame = +3
Query: 9 REHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLNLA 188
REHAALEPRHLGGR II KSFARIHETNLKKQG+LPLTF+ P DYNKI P DK+++ L
Sbjct: 671 REHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIQGLK 730
Query: 189 KFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMRE 329
F P KP++C IKH +G +E I LNHTFN+ QI+WF+AGSALNRM+E
Sbjct: 731 DFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>sp|P16276|ACON_PIG Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 781
Score = 165 bits (417), Expect = 5e-41
Identities = 76/107 (71%), Positives = 89/107 (83%)
Frame = +3
Query: 9 REHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLNLA 188
REH ALEPRHLGGR II KSFARIHETNLKKQG+LPLTF+ P DYNKI P DK+++ L
Sbjct: 671 REHRALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIQGLK 730
Query: 189 KFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMRE 329
FAP KP++C IKH +G +E I LNHTFN+ QI+WF+AGSALNRM+E
Sbjct: 731 DFAPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>sp|P34455|ACON_CAEEL Probable aconitate hydratase, mitochondrial precursor (Citrate
hydro-lyase) (Aconitase)
Length = 777
Score = 164 bits (416), Expect = 7e-41
Identities = 77/107 (71%), Positives = 90/107 (84%)
Frame = +3
Query: 9 REHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLNLA 188
REHAALEPRHLGGR IIVKSFARIHETNLKKQGMLPLTF+ P DY+KI PSD +S++ L+
Sbjct: 665 REHAALEPRHLGGRAIIVKSFARIHETNLKKQGMLPLTFANPADYDKIDPSDNVSIVGLS 724
Query: 189 KFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMRE 329
FAP KP+ K +G+K +TLNHTFN+ QI+WFKAGSALNRM+E
Sbjct: 725 SFAPGKPLTAIFKKTNGSKVEVTLNHTFNEQQIEWFKAGSALNRMKE 771
>sp|P49609|ACON_GRAVE Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 779
Score = 145 bits (365), Expect = 5e-35
Identities = 68/106 (64%), Positives = 81/106 (76%)
Frame = +3
Query: 9 REHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLNLA 188
REHAALEPRHLGG +IVKSFARIHETNLKKQGMLPLTF+ P DY+KI SDK+SL+ L
Sbjct: 669 REHAALEPRHLGGVAVIVKSFARIHETNLKKQGMLPLTFNNPADYDKIDSSDKVSLVGLK 728
Query: 189 KFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMR 326
P +PV + DG I LNHTFN Q++WF+AGSALN+++
Sbjct: 729 NLTPGEPVTMTVTKADGTSMDILLNHTFNDEQLEWFRAGSALNKIK 774
>sp|O13966|ACON_SCHPO Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 778
Score = 137 bits (346), Expect = 9e-33
Identities = 68/106 (64%), Positives = 80/106 (75%), Gaps = 1/106 (0%)
Frame = +3
Query: 9 REHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLNLA 188
REHAALEPR+LGG +I KSFARIHETNLKKQG+LPLTF+ P Y+KI P D + + L
Sbjct: 666 REHAALEPRYLGGAAVITKSFARIHETNLKKQGLLPLTFADPAAYDKISPFDTVDIDGLT 725
Query: 189 KFAPEKPVECEIKHKDGAKEVIT-LNHTFNKNQIDWFKAGSALNRM 323
FAP KP+ + DG+ E T LNHTFNK+QI+WFKAGSALN M
Sbjct: 726 TFAPGKPLTLVVHPADGSAEWSTKLNHTFNKDQIEWFKAGSALNHM 771
>sp|P19414|ACON_YEAST Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 778
Score = 137 bits (344), Expect = 1e-32
Identities = 66/106 (62%), Positives = 77/106 (72%)
Frame = +3
Query: 9 REHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLNLA 188
REHAALEPR LGG II KSFARIHETNLKKQG+LPL F P DY+KI P D+I +L LA
Sbjct: 668 REHAALEPRFLGGFAIITKSFARIHETNLKKQGLLPLNFKNPADYDKINPDDRIDILGLA 727
Query: 189 KFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMR 326
+ AP KPV + K+G L HTFN QI+WFK GSALN+++
Sbjct: 728 ELAPGKPVTMRVHPKNGKPWDAVLTHTFNDEQIEWFKYGSALNKIK 773
>sp|P39533|ACON2_YEAST Putative aconitase in PRP21-UBP12 intergenic region
Length = 789
Score = 111 bits (277), Expect = 9e-25
Identities = 56/108 (51%), Positives = 72/108 (66%), Gaps = 5/108 (4%)
Frame = +3
Query: 9 REHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLNLA 188
REHAAL PR LGG +++VKSFARIHETNLKKQG+LPLTF+ DY+KI D + LNL
Sbjct: 673 REHAALSPRFLGGEILLVKSFARIHETNLKKQGVLPLTFANESDYDKISSGDVLETLNLV 732
Query: 189 KFAPEK-----PVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALN 317
+ ++ +I +G I HT +K+QID+FKAGSA+N
Sbjct: 733 DMIAKDGNNGGEIDVKITKPNGESFTIKAKHTMSKDQIDFFKAGSAIN 780
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,849,364
Number of Sequences: 369166
Number of extensions: 923800
Number of successful extensions: 3085
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3015
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3079
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2534533995
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)