Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_O13
(637 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99KI0|ACON_MOUSE Aconitate hydratase, mitochondrial pre... 259 5e-69
sp|Q9ER34|ACON_RAT Aconitate hydratase, mitochondrial precu... 258 9e-69
sp|P20004|ACON_BOVIN Aconitate hydratase, mitochondrial pre... 257 2e-68
sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial pre... 256 3e-68
sp|P34455|ACON_CAEEL Probable aconitate hydratase, mitochon... 253 4e-67
sp|P16276|ACON_PIG Aconitate hydratase, mitochondrial precu... 251 8e-67
sp|P49609|ACON_GRAVE Aconitate hydratase, mitochondrial pre... 241 9e-64
sp|P19414|ACON_YEAST Aconitate hydratase, mitochondrial pre... 221 1e-57
sp|O13966|ACON_SCHPO Aconitate hydratase, mitochondrial pre... 211 1e-54
sp|P39533|ACON2_YEAST Putative aconitase in PRP21-UBP12 int... 168 9e-42
>sp|Q99KI0|ACON_MOUSE Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 780
Score = 259 bits (661), Expect = 5e-69
Identities = 121/169 (71%), Positives = 141/169 (83%)
Frame = +1
Query: 1 HLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIGDENYGEG 180
HLDNISNN+ IGA+N ENG+ N VR+ VT ++ VP TAR YKK GI WVVIGDENYGEG
Sbjct: 609 HLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEG 668
Query: 181 SSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLN 360
SSREHAALEPRHLGGR II KSFARIHETNLKKQG+LPLTF+ P DYNKI P DK+++
Sbjct: 669 SSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPSDYNKIHPVDKLTIQG 728
Query: 361 LAKFAPEKPVECEIKHKDGAKEVIILNHTFNKNQIDWFKAGSALNRMRE 507
L FAP KP++C IKH +G +E I+LNHTFN+ QI+WF+AGSALNRM+E
Sbjct: 729 LKDFAPGKPLKCVIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>sp|Q9ER34|ACON_RAT Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 780
Score = 258 bits (659), Expect = 9e-69
Identities = 121/169 (71%), Positives = 140/169 (82%)
Frame = +1
Query: 1 HLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIGDENYGEG 180
HLDNISNN+ IGA+N ENG+ N VR+ VT ++ VP TAR YKK GI WVVIGDENYGEG
Sbjct: 609 HLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEG 668
Query: 181 SSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLN 360
SSREHAALEPRHLGGR II KSFARIHETNLKKQG+LPLTF+ P DYNKI P DK+++
Sbjct: 669 SSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPSDYNKIHPVDKLTIQG 728
Query: 361 LAKFAPEKPVECEIKHKDGAKEVIILNHTFNKNQIDWFKAGSALNRMRE 507
L FAP KP+ C IKH +G +E I+LNHTFN+ QI+WF+AGSALNRM+E
Sbjct: 729 LKDFAPGKPLNCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>sp|P20004|ACON_BOVIN Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 780
Score = 257 bits (657), Expect = 2e-68
Identities = 121/169 (71%), Positives = 140/169 (82%)
Frame = +1
Query: 1 HLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIGDENYGEG 180
HLDNISNN+ IGA+N ENG+ N VR+ VT ++ VP TAR YKK GI WVVIGDENYGEG
Sbjct: 609 HLDNISNNLLIGAINVENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEG 668
Query: 181 SSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLN 360
SSREHAALEPRHLGGR II KSFARIHETNLKKQG+LPLTF+ P DYNKI P DK+++
Sbjct: 669 SSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIKG 728
Query: 361 LAKFAPEKPVECEIKHKDGAKEVIILNHTFNKNQIDWFKAGSALNRMRE 507
L FAP KP+ C IKH +G +E I+LNHTFN+ QI+WF+AGSALNRM+E
Sbjct: 729 LKDFAPGKPLTCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 780
Score = 256 bits (655), Expect = 3e-68
Identities = 120/169 (71%), Positives = 140/169 (82%)
Frame = +1
Query: 1 HLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIGDENYGEG 180
HLDNISNN+ IGA+N ENG+ N VR+ VT ++ VP TAR YKK GI WVVIGDENYGEG
Sbjct: 609 HLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEG 668
Query: 181 SSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLN 360
SSREHAALEPRHLGGR II KSFARIHETNLKKQG+LPLTF+ P DYNKI P DK+++
Sbjct: 669 SSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIQG 728
Query: 361 LAKFAPEKPVECEIKHKDGAKEVIILNHTFNKNQIDWFKAGSALNRMRE 507
L F P KP++C IKH +G +E I+LNHTFN+ QI+WF+AGSALNRM+E
Sbjct: 729 LKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>sp|P34455|ACON_CAEEL Probable aconitate hydratase, mitochondrial precursor (Citrate
hydro-lyase) (Aconitase)
Length = 777
Score = 253 bits (645), Expect = 4e-67
Identities = 117/169 (69%), Positives = 142/169 (84%)
Frame = +1
Query: 1 HLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIGDENYGEG 180
HLDNISNN+F+ A+N++NGE+NKV++ VTG++ VP+TAR YK G+ WV IGDENYGEG
Sbjct: 603 HLDNISNNLFLTAINADNGEMNKVKNQVTGEYGAVPATARKYKADGVRWVAIGDENYGEG 662
Query: 181 SSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLN 360
SSREHAALEPRHLGGR IIVKSFARIHETNLKKQGMLPLTF+ P DY+KI PSD +S++
Sbjct: 663 SSREHAALEPRHLGGRAIIVKSFARIHETNLKKQGMLPLTFANPADYDKIDPSDNVSIVG 722
Query: 361 LAKFAPEKPVECEIKHKDGAKEVIILNHTFNKNQIDWFKAGSALNRMRE 507
L+ FAP KP+ K +G+K + LNHTFN+ QI+WFKAGSALNRM+E
Sbjct: 723 LSSFAPGKPLTAIFKKTNGSKVEVTLNHTFNEQQIEWFKAGSALNRMKE 771
>sp|P16276|ACON_PIG Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 781
Score = 251 bits (642), Expect = 8e-67
Identities = 118/169 (69%), Positives = 139/169 (82%)
Frame = +1
Query: 1 HLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIGDENYGEG 180
HLDNISNN+ IGA+N EN + N VR+ VT ++ VP TAR YK+ GI WVVIGDENYGEG
Sbjct: 609 HLDNISNNLLIGAINIENRKANSVRNAVTQEFGPVPDTARYYKQHGIRWVVIGDENYGEG 668
Query: 181 SSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLN 360
SSREH ALEPRHLGGR II KSFARIHETNLKKQG+LPLTF+ P DYNKI P DK+++
Sbjct: 669 SSREHRALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIQG 728
Query: 361 LAKFAPEKPVECEIKHKDGAKEVIILNHTFNKNQIDWFKAGSALNRMRE 507
L FAP KP++C IKH +G +E I+LNHTFN+ QI+WF+AGSALNRM+E
Sbjct: 729 LKDFAPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>sp|P49609|ACON_GRAVE Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 779
Score = 241 bits (616), Expect = 9e-64
Identities = 113/168 (67%), Positives = 133/168 (79%)
Frame = +1
Query: 1 HLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIGDENYGEG 180
HLDNISNNM IGAVN ENGE+N V++ VTG++ VP TAR YK G+ WVVIGDENYGEG
Sbjct: 607 HLDNISNNMLIGAVNDENGEINNVKNAVTGEYGTVPDTARAYKAEGVKWVVIGDENYGEG 666
Query: 181 SSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLN 360
SSREHAALEPRHLGG +IVKSFARIHETNLKKQGMLPLTF+ P DY+KI SDK+SL+
Sbjct: 667 SSREHAALEPRHLGGVAVIVKSFARIHETNLKKQGMLPLTFNNPADYDKIDSSDKVSLVG 726
Query: 361 LAKFAPEKPVECEIKHKDGAKEVIILNHTFNKNQIDWFKAGSALNRMR 504
L P +PV + DG I+LNHTFN Q++WF+AGSALN+++
Sbjct: 727 LKNLTPGEPVTMTVTKADGTSMDILLNHTFNDEQLEWFRAGSALNKIK 774
>sp|P19414|ACON_YEAST Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 778
Score = 221 bits (563), Expect = 1e-57
Identities = 105/168 (62%), Positives = 128/168 (76%)
Frame = +1
Query: 1 HLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIGDENYGEG 180
HL+NISNN IGA+N+EN + N V++V TG++ VP TAR+Y+ GI WVVIGDEN+GEG
Sbjct: 606 HLENISNNYMIGAINAENKKANCVKNVYTGEYKGVPDTARDYRDQGIKWVVIGDENFGEG 665
Query: 181 SSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLN 360
SSREHAALEPR LGG II KSFARIHETNLKKQG+LPL F P DY+KI P D+I +L
Sbjct: 666 SSREHAALEPRFLGGFAIITKSFARIHETNLKKQGLLPLNFKNPADYDKINPDDRIDILG 725
Query: 361 LAKFAPEKPVECEIKHKDGAKEVIILNHTFNKNQIDWFKAGSALNRMR 504
LA+ AP KPV + K+G +L HTFN QI+WFK GSALN+++
Sbjct: 726 LAELAPGKPVTMRVHPKNGKPWDAVLTHTFNDEQIEWFKYGSALNKIK 773
>sp|O13966|ACON_SCHPO Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
(Aconitase)
Length = 778
Score = 211 bits (538), Expect = 1e-54
Identities = 101/168 (60%), Positives = 127/168 (75%), Gaps = 1/168 (0%)
Frame = +1
Query: 1 HLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIGDENYGEG 180
HL NISNN IGA+N+ENGE NK++ +TG++ VP+ A +Y+ GI WV +G++N+GEG
Sbjct: 604 HLQNISNNYMIGAINAENGEANKLKDQLTGEYKTVPNVAIDYRDHGIRWVTLGEQNFGEG 663
Query: 181 SSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLN 360
SSREHAALEPR+LGG +I KSFARIHETNLKKQG+LPLTF+ P Y+KI P D + +
Sbjct: 664 SSREHAALEPRYLGGAAVITKSFARIHETNLKKQGLLPLTFADPAAYDKISPFDTVDIDG 723
Query: 361 LAKFAPEKPVECEIKHKDGAKE-VIILNHTFNKNQIDWFKAGSALNRM 501
L FAP KP+ + DG+ E LNHTFNK+QI+WFKAGSALN M
Sbjct: 724 LTTFAPGKPLTLVVHPADGSAEWSTKLNHTFNKDQIEWFKAGSALNHM 771
>sp|P39533|ACON2_YEAST Putative aconitase in PRP21-UBP12 intergenic region
Length = 789
Score = 168 bits (426), Expect = 9e-42
Identities = 87/170 (51%), Positives = 110/170 (64%), Gaps = 5/170 (2%)
Frame = +1
Query: 1 HLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIGDENYGEG 180
HL+NIS N IGA N E GEVNK + + G D+P +K G PW VI + NYGEG
Sbjct: 612 HLENISYNTLIGAQNKETGEVNKA-YDLDGTEYDIPGLMMKWKSDGRPWTVIAEHNYGEG 670
Query: 181 SSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPSDKISLLN 360
S+REHAAL PR LGG +++VKSFARIHETNLKKQG+LPLTF+ DY+KI D + LN
Sbjct: 671 SAREHAALSPRFLGGEILLVKSFARIHETNLKKQGVLPLTFANESDYDKISSGDVLETLN 730
Query: 361 LAKFAPEK-----PVECEIKHKDGAKEVIILNHTFNKNQIDWFKAGSALN 495
L + ++ +I +G I HT +K+QID+FKAGSA+N
Sbjct: 731 LVDMIAKDGNNGGEIDVKITKPNGESFTIKAKHTMSKDQIDFFKAGSAIN 780
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,863,403
Number of Sequences: 369166
Number of extensions: 1411393
Number of successful extensions: 4647
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4514
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4641
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5121172350
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)