Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01030 (1261 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P46467|VPS4B_MOUSE Vacuolar sorting protein 4b (SKD1 pro... 363 e-100 sp|O75351|VPS4B_HUMAN Vacuolar sorting protein 4b (SKD1 pro... 360 4e-99 sp|Q8VEJ9|VPS4A_MOUSE Vacuolar sorting protein 4a 353 8e-97 sp|Q9UN37|VPS4A_HUMAN Vacuolar sorting protein 4a (SKD2 pro... 350 4e-96 sp|Q09803|VPS4_SCHPO Suppressor protein of bem1/bed5 double... 300 6e-81 sp|P52917|VPS4_YEAST Vacuolar protein sorting-associated pr... 289 1e-77 sp|Q5XIK7|KATL1_RAT Katanin p60 ATPase-containing subunit A... 173 1e-42 sp|Q8K0T4|KATL1_MOUSE Katanin p60 ATPase-containing subunit... 172 2e-42 sp|Q9BW62|KATL1_HUMAN Katanin p60 ATPase-containing subunit... 170 7e-42 sp|Q6E0V2|KTNA1_RAT Katanin p60 ATPase-containing subunit A... 165 3e-40
>sp|P46467|VPS4B_MOUSE Vacuolar sorting protein 4b (SKD1 protein) Length = 444 Score = 363 bits (931), Expect = e-100 Identities = 185/274 (67%), Positives = 215/274 (78%) Frame = +1 Query: 34 IFY*PPGTGKSYLAKAVATEAXXXXXXXXXXXXXXXKWLGESEKLVKSLFEVAREKKPSI 213 + + PPGTGKSYLAKAVATEA KWLGESEKLVK+LF++ARE KPSI Sbjct: 171 LLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSI 230 Query: 214 IFIDEIDSLCSNRGDNDSESAKRIKTEFLVQMQGVSSDNDNVLILAATNIPWALDSAIRR 393 IFIDEIDSLC +R +N+SE+A+RIKTEFLVQMQGV DND +L+L ATNIPW LDSAIRR Sbjct: 231 IFIDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRR 290 Query: 394 RFEKRIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDA 573 RFEKRIYI LPEA ARA MF+L +G+ Q+ LT +F ELG ++GYSGADISI VRDA Sbjct: 291 RFEKRIYIPLPEAHARAAMFRLHLGST--QNSLTEADFQELGRKTDGYSGADISIIVRDA 348 Query: 574 LMVPVRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPC 753 LM PVRKVQ+ATHF++VRGPS DP+ IV+DLLTPCSPG PGAIEM W V +KLLEP Sbjct: 349 LMQPVRKVQSATHFKKVRGPSRADPNCIVNDLLTPCSPGDPGAIEMTWMDVPGDKLLEPV 408 Query: 754 VTFADMKLALSRNKPTVNQKDLEKLIQFTTDFGQ 855 V+ DM +LS KPTVN++DL KL +FT DFGQ Sbjct: 409 VSMWDMLRSLSSTKPTVNEQDLLKLKKFTEDFGQ 442
>sp|O75351|VPS4B_HUMAN Vacuolar sorting protein 4b (SKD1 protein) Length = 444 Score = 360 bits (925), Expect = 4e-99 Identities = 184/274 (67%), Positives = 212/274 (77%) Frame = +1 Query: 34 IFY*PPGTGKSYLAKAVATEAXXXXXXXXXXXXXXXKWLGESEKLVKSLFEVAREKKPSI 213 + + PPGTGKSYLAKAVATEA KWLGESEKLVK+LF++ARE KPSI Sbjct: 171 LLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSI 230 Query: 214 IFIDEIDSLCSNRGDNDSESAKRIKTEFLVQMQGVSSDNDNVLILAATNIPWALDSAIRR 393 IFIDEIDSLC +R +N+SE+A+RIKTEFLVQMQGV DND +L+L ATNIPW LDSAIRR Sbjct: 231 IFIDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRR 290 Query: 394 RFEKRIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDA 573 RFEKRIYI LPE ARA MFKL +G Q+ LT +F ELG ++GYSGADISI VRDA Sbjct: 291 RFEKRIYIPLPEPHARAAMFKLHLGTT--QNSLTEADFRELGRKTDGYSGADISIIVRDA 348 Query: 574 LMVPVRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPC 753 LM PVRKVQ+ATHF++VRGPS DP+ +V DLLTPCSPG PGAIEM W V +KLLEP Sbjct: 349 LMQPVRKVQSATHFKKVRGPSRADPNHLVDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPV 408 Query: 754 VTFADMKLALSRNKPTVNQKDLEKLIQFTTDFGQ 855 V+ +DM +LS KPTVN+ DL KL +FT DFGQ Sbjct: 409 VSMSDMLRSLSNTKPTVNEHDLLKLKKFTEDFGQ 442
>sp|Q8VEJ9|VPS4A_MOUSE Vacuolar sorting protein 4a Length = 437 Score = 353 bits (905), Expect = 8e-97 Identities = 177/274 (64%), Positives = 212/274 (77%) Frame = +1 Query: 34 IFY*PPGTGKSYLAKAVATEAXXXXXXXXXXXXXXXKWLGESEKLVKSLFEVAREKKPSI 213 + + PPGTGKSYLAKAVATEA KWLGESEKLVK+LFE+AR+ KPSI Sbjct: 164 LLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSI 223 Query: 214 IFIDEIDSLCSNRGDNDSESAKRIKTEFLVQMQGVSSDNDNVLILAATNIPWALDSAIRR 393 IFIDE+DSLC +R +N+SE+A+RIKTEFLVQMQGV ++ND L+L ATNIPW LDSAIRR Sbjct: 224 IFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRR 283 Query: 394 RFEKRIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDA 573 RFEKRIYI LPE ARA+MF+L +G+ P H+LT N EL +EGYSGADISI VRD+ Sbjct: 284 RFEKRIYIPLPEEAARAQMFRLHLGSTP--HNLTDANIHELARKTEGYSGADISIIVRDS 341 Query: 574 LMVPVRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPC 753 LM PVRKVQ+ATHF++V GPS T+PSV++ DLLTPCSPG PGAIEM W V +KLLEP Sbjct: 342 LMQPVRKVQSATHFKKVCGPSRTNPSVMIDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPV 401 Query: 754 VTFADMKLALSRNKPTVNQKDLEKLIQFTTDFGQ 855 V +DM +L+ +PTVN DL K+ +F+ DFGQ Sbjct: 402 VCMSDMLRSLATTRPTVNADDLLKVKKFSEDFGQ 435
>sp|Q9UN37|VPS4A_HUMAN Vacuolar sorting protein 4a (SKD2 protein) (hVPS4) (VPS4-1) Length = 437 Score = 350 bits (899), Expect = 4e-96 Identities = 175/274 (63%), Positives = 212/274 (77%) Frame = +1 Query: 34 IFY*PPGTGKSYLAKAVATEAXXXXXXXXXXXXXXXKWLGESEKLVKSLFEVAREKKPSI 213 + + PPGTGKSYLAKAVATEA KWLGESEKLVK+LFE+AR+ KPSI Sbjct: 164 LLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSI 223 Query: 214 IFIDEIDSLCSNRGDNDSESAKRIKTEFLVQMQGVSSDNDNVLILAATNIPWALDSAIRR 393 IFIDE+DSLC +R +N+SE+A+RIKTEFLVQMQGV ++ND L+L ATNIPW LDSAIRR Sbjct: 224 IFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRR 283 Query: 394 RFEKRIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDA 573 RFEKRIYI LPE ARA+MF+L +G+ P H+LT N EL +EGYSGADISI VRD+ Sbjct: 284 RFEKRIYIPLPEEAARAQMFRLHLGSTP--HNLTDANIHELARKTEGYSGADISIIVRDS 341 Query: 574 LMVPVRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPC 753 LM PVRKVQ+ATHF++V GPS T+PS+++ DLLTPCSPG PGA+EM W V +KLLEP Sbjct: 342 LMQPVRKVQSATHFKKVCGPSRTNPSMMIDDLLTPCSPGDPGAMEMTWMDVPGDKLLEPV 401 Query: 754 VTFADMKLALSRNKPTVNQKDLEKLIQFTTDFGQ 855 V +DM +L+ +PTVN DL K+ +F+ DFGQ Sbjct: 402 VCMSDMLRSLATTRPTVNADDLLKVKKFSEDFGQ 435
>sp|Q09803|VPS4_SCHPO Suppressor protein of bem1/bed5 double mutants Length = 432 Score = 300 bits (768), Expect = 6e-81 Identities = 157/273 (57%), Positives = 192/273 (70%) Frame = +1 Query: 34 IFY*PPGTGKSYLAKAVATEAXXXXXXXXXXXXXXXKWLGESEKLVKSLFEVAREKKPSI 213 + Y PPGTGKSYLAKAVATEA KW+GESE+LV+ LFE+ARE+KPSI Sbjct: 166 LLYGPPGTGKSYLAKAVATEAGSTFFSISSSDLVS-KWMGESERLVRQLFEMAREQKPSI 224 Query: 214 IFIDEIDSLCSNRGDNDSESAKRIKTEFLVQMQGVSSDNDNVLILAATNIPWALDSAIRR 393 IFIDEIDSLC +R + +SES++RIKTEFLVQM GV D VL+L ATNIPW LDSAIRR Sbjct: 225 IFIDEIDSLCGSRSEGESESSRRIKTEFLVQMNGVGKDESGVLVLGATNIPWTLDSAIRR 284 Query: 394 RFEKRIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDA 573 RFEKRIYI LP A ARA MF+L++G P +LT Q+F EL +++GYSG+DISI VRDA Sbjct: 285 RFEKRIYIPLPNAHARARMFELNVGKIPS--ELTSQDFKELAKMTDGYSGSDISIVVRDA 342 Query: 574 LMVPVRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPC 753 +M PVR++ TATHF+ V L+TPCSPG P A E +W V+ E ++EP Sbjct: 343 IMEPVRRIHTATHFKEVYDNKSN------RTLVTPCSPGDPDAFESSWLEVNPEDIMEPK 396 Query: 754 VTFADMKLALSRNKPTVNQKDLEKLIQFTTDFG 852 +T D A+ + KPT+N D+EK QFT DFG Sbjct: 397 LTVRDFYSAVRKVKPTLNAGDIEKHTQFTKDFG 429
>sp|P52917|VPS4_YEAST Vacuolar protein sorting-associated protein VPS4 (END13 protein) (DOA4-independent degradation protein 6) Length = 437 Score = 289 bits (740), Expect = 1e-77 Identities = 151/274 (55%), Positives = 195/274 (71%) Frame = +1 Query: 34 IFY*PPGTGKSYLAKAVATEAXXXXXXXXXXXXXXXKWLGESEKLVKSLFEVAREKKPSI 213 + Y PPGTGKSYLAKAVATEA KW+GESEKLVK LF +ARE KPSI Sbjct: 170 LLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVS-KWMGESEKLVKQLFAMARENKPSI 228 Query: 214 IFIDEIDSLCSNRGDNDSESAKRIKTEFLVQMQGVSSDNDNVLILAATNIPWALDSAIRR 393 IFIDE+D+L RG+ +SE+++RIKTE LVQM GV +D+ VL+L ATNIPW LDSAIRR Sbjct: 229 IFIDEVDALTGTRGEGESEASRRIKTELLVQMNGVGNDSQGVLVLGATNIPWQLDSAIRR 288 Query: 394 RFEKRIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDA 573 RFE+RIYI LP+ AR MF++++G+ P LT +++ LG ++EGYSG+DI++ V+DA Sbjct: 289 RFERRIYIPLPDLAARTTMFEINVGDTPCV--LTKEDYRTLGAMTEGYSGSDIAVVVKDA 346 Query: 574 LMVPVRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPC 753 LM P+RK+Q+ATHF+ V S D + LTPCSPG GAIEM+W +++++L EP Sbjct: 347 LMQPIRKIQSATHFKDV---STEDDE---TRKLTPCSPGDDGAIEMSWTDIEADELKEPD 400 Query: 754 VTFADMKLALSRNKPTVNQKDLEKLIQFTTDFGQ 855 +T D A+ +PTVN+ DL K QFT DFGQ Sbjct: 401 LTIKDFLKAIKSTRPTVNEDDLLKQEQFTRDFGQ 434
>sp|Q5XIK7|KATL1_RAT Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit A-like 1) (p60 katanin-like 1) Length = 488 Score = 173 bits (438), Expect = 1e-42 Identities = 112/276 (40%), Positives = 157/276 (56%), Gaps = 7/276 (2%) Frame = +1 Query: 46 PPGTGKSYLAKAVATEAXXXXXXXXXXXXXXXKWLGESEKLVKSLFEVAREKKPSIIFID 225 PPGTGK+ LAKAVATE K+ GESEKLV+ LFE+AR P+ IFID Sbjct: 247 PPGTGKTMLAKAVATECGTTFFNVSSSTLTS-KYRGESEKLVRLLFEMARFYAPTTIFID 305 Query: 226 EIDSLCSNRGDNDS-ESAKRIKTEFLVQMQGVSS--DNDN----VLILAATNIPWALDSA 384 EIDS+CS RG +D E+++R+K+E L+QM GV +ND+ V++LAATN PW +D A Sbjct: 306 EIDSICSRRGTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEA 365 Query: 385 IRRRFEKRIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAV 564 +RRR EKRIYI LP A RAE+ K+S+ D+ + ++ +EGYSGADI+ Sbjct: 366 LRRRLEKRIYIPLPTAKGRAELLKISLREVELDPDI---HLEDIAEKTEGYSGADITNIC 422 Query: 565 RDALMVPVRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLL 744 RDA ++ +R RR+ G SP + + S++ L Sbjct: 423 RDASLMAMR--------RRINGLSPEEIRAL------------------------SKEEL 450 Query: 745 EPCVTFADMKLALSRNKPTVNQKDLEKLIQFTTDFG 852 + VT D++LAL + +V+ DLEK ++ +FG Sbjct: 451 QMPVTRGDLELALKKIAKSVSAADLEKYEKWMVEFG 486
>sp|Q8K0T4|KATL1_MOUSE Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit A-like 1) (p60 katanin-like 1) Length = 488 Score = 172 bits (436), Expect = 2e-42 Identities = 112/276 (40%), Positives = 157/276 (56%), Gaps = 7/276 (2%) Frame = +1 Query: 46 PPGTGKSYLAKAVATEAXXXXXXXXXXXXXXXKWLGESEKLVKSLFEVAREKKPSIIFID 225 PPGTGK+ LAKAVATE K+ GESEKLV+ LFE+AR P+ IFID Sbjct: 247 PPGTGKTMLAKAVATECGTTFFNVSSSTLTS-KYRGESEKLVRLLFEMARFYAPTTIFID 305 Query: 226 EIDSLCSNRGDNDS-ESAKRIKTEFLVQMQGVSS--DNDN----VLILAATNIPWALDSA 384 EIDS+CS RG +D E+++R+K+E L+QM GV +ND+ V++LAATN PW +D A Sbjct: 306 EIDSICSRRGTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEA 365 Query: 385 IRRRFEKRIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAV 564 +RRR EKRIYI LP A RAE+ K+S+ D+ + ++ +EGYSGADI+ Sbjct: 366 LRRRLEKRIYIPLPTAKGRAELLKISLREVELDPDV---HLEDIADKTEGYSGADITNIC 422 Query: 565 RDALMVPVRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLL 744 RDA ++ +R RR+ G SP + + S++ L Sbjct: 423 RDASLMAMR--------RRINGLSPEEIRAL------------------------SKEEL 450 Query: 745 EPCVTFADMKLALSRNKPTVNQKDLEKLIQFTTDFG 852 + VT D++LAL + +V+ DLEK ++ +FG Sbjct: 451 QMPVTRGDLELALKKIAKSVSAADLEKYEKWMVEFG 486
>sp|Q9BW62|KATL1_HUMAN Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit A-like 1) (p60 katanin-like 1) Length = 490 Score = 170 bits (431), Expect = 7e-42 Identities = 112/276 (40%), Positives = 156/276 (56%), Gaps = 7/276 (2%) Frame = +1 Query: 46 PPGTGKSYLAKAVATEAXXXXXXXXXXXXXXXKWLGESEKLVKSLFEVAREKKPSIIFID 225 PPGTGK+ LAKAVATE K+ GESEKLV+ LFE+AR P+ IFID Sbjct: 249 PPGTGKTMLAKAVATECGTTFFNVSSSTLTS-KYRGESEKLVRLLFEMARFYAPTTIFID 307 Query: 226 EIDSLCSNRGDNDS-ESAKRIKTEFLVQMQGVSS--DNDN----VLILAATNIPWALDSA 384 EIDS+CS RG +D E+++R+K+E L+QM GV +ND+ V++LAATN PW +D A Sbjct: 308 EIDSICSRRGTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEA 367 Query: 385 IRRRFEKRIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAV 564 +RRR EKRIYI LP A RAE+ K+++ D+ ++ +E EGYSGADI+ Sbjct: 368 LRRRLEKRIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAE---KIEGYSGADITNVC 424 Query: 565 RDALMVPVRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLL 744 RDA ++ +R RR+ G SP + + S++ L Sbjct: 425 RDASLMAMR--------RRINGLSPEEIRAL------------------------SKEEL 452 Query: 745 EPCVTFADMKLALSRNKPTVNQKDLEKLIQFTTDFG 852 + VT D +LAL + +V+ DLEK ++ +FG Sbjct: 453 QMPVTKGDFELALKKIAKSVSAADLEKYEKWMVEFG 488
>sp|Q6E0V2|KTNA1_RAT Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (p60 katanin) Length = 491 Score = 165 bits (417), Expect = 3e-40 Identities = 110/276 (39%), Positives = 153/276 (55%), Gaps = 7/276 (2%) Frame = +1 Query: 46 PPGTGKSYLAKAVATEAXXXXXXXXXXXXXXXKWLGESEKLVKSLFEVAREKKPSIIFID 225 PPGTGK+ LAKAVATE K+ GESEKLV+ LFE+AR P+ IFID Sbjct: 250 PPGTGKTLLAKAVATECKTTFFNVSSSTLTS-KYRGESEKLVRLLFEMARFYSPATIFID 308 Query: 226 EIDSLCSNRGDNDS-ESAKRIKTEFLVQMQGV--SSDNDN----VLILAATNIPWALDSA 384 EIDS+CS RG ++ E+++R+K E LVQM GV +S+ND+ V++LAATN PW +D A Sbjct: 309 EIDSICSRRGTSEEHEASRRVKAELLVQMDGVGGASENDDPSKMVMVLAATNFPWDIDEA 368 Query: 385 IRRRFEKRIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAV 564 +RRR EKRIYI LP A R E+ ++S+ D+ N + + EGYSGADI+ Sbjct: 369 LRRRLEKRIYIPLPSAKGREELLRISLRELELADDV---NLASIAENMEGYSGADITNVC 425 Query: 565 RDALMVPVRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLL 744 RDA ++ +R RR+ G LTP + EM+ T Sbjct: 426 RDASLMAMR--------RRIEG-------------LTPEEIRNLSREEMHMPT------- 457 Query: 745 EPCVTFADMKLALSRNKPTVNQKDLEKLIQFTTDFG 852 T D ++AL + +V+ D+E+ ++ +FG Sbjct: 458 ----TMEDFEMALKKVSKSVSAADIERYEKWIVEFG 489
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 138,262,166 Number of Sequences: 369166 Number of extensions: 2816392 Number of successful extensions: 11617 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 9487 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 10854 length of database: 68,354,980 effective HSP length: 113 effective length of database: 47,479,925 effective search space used: 14528857050 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)