Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_D18
(554 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P46467|VPS4B_MOUSE Vacuolar sorting protein 4b (SKD1 pro... 191 8e-49
sp|O75351|VPS4B_HUMAN Vacuolar sorting protein 4b (SKD1 pro... 189 4e-48
sp|Q8VEJ9|VPS4A_MOUSE Vacuolar sorting protein 4a 184 1e-46
sp|Q9UN37|VPS4A_HUMAN Vacuolar sorting protein 4a (SKD2 pro... 182 6e-46
sp|Q09803|VPS4_SCHPO Suppressor protein of bem1/bed5 double... 141 1e-33
sp|P52917|VPS4_YEAST Vacuolar protein sorting-associated pr... 138 8e-33
sp|Q5XIK7|KATL1_RAT Katanin p60 ATPase-containing subunit A... 59 8e-09
sp|Q8K0T4|KATL1_MOUSE Katanin p60 ATPase-containing subunit... 58 1e-08
sp|Q9BW62|KATL1_HUMAN Katanin p60 ATPase-containing subunit... 56 5e-08
sp|O61577|KTNA1_STRPU Katanin p60 ATPase-containing subunit... 52 1e-06
>sp|P46467|VPS4B_MOUSE Vacuolar sorting protein 4b (SKD1 protein)
Length = 444
Score = 191 bits (486), Expect = 8e-49
Identities = 98/150 (65%), Positives = 116/150 (77%)
Frame = +3
Query: 3 RIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDALMVP 182
RIYI LPEA ARA MF+L +G+ Q+ LT +F ELG ++GYSGADISI VRDALM P
Sbjct: 295 RIYIPLPEAHARAAMFRLHLGST--QNSLTEADFQELGRKTDGYSGADISIIVRDALMQP 352
Query: 183 VRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPCVTFA 362
VRKVQ+ATHF++VRGPS DP+ IV+DLLTPCSPG PGAIEM W V +KLLEP V+
Sbjct: 353 VRKVQSATHFKKVRGPSRADPNCIVNDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVSMW 412
Query: 363 DMKLALSRNKPTVNQKDLEKLIQFTTDFGQ 452
DM +LS KPTVN++DL KL +FT DFGQ
Sbjct: 413 DMLRSLSSTKPTVNEQDLLKLKKFTEDFGQ 442
>sp|O75351|VPS4B_HUMAN Vacuolar sorting protein 4b (SKD1 protein)
Length = 444
Score = 189 bits (480), Expect = 4e-48
Identities = 97/150 (64%), Positives = 113/150 (75%)
Frame = +3
Query: 3 RIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDALMVP 182
RIYI LPE ARA MFKL +G Q+ LT +F ELG ++GYSGADISI VRDALM P
Sbjct: 295 RIYIPLPEPHARAAMFKLHLGTT--QNSLTEADFRELGRKTDGYSGADISIIVRDALMQP 352
Query: 183 VRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPCVTFA 362
VRKVQ+ATHF++VRGPS DP+ +V DLLTPCSPG PGAIEM W V +KLLEP V+ +
Sbjct: 353 VRKVQSATHFKKVRGPSRADPNHLVDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVSMS 412
Query: 363 DMKLALSRNKPTVNQKDLEKLIQFTTDFGQ 452
DM +LS KPTVN+ DL KL +FT DFGQ
Sbjct: 413 DMLRSLSNTKPTVNEHDLLKLKKFTEDFGQ 442
>sp|Q8VEJ9|VPS4A_MOUSE Vacuolar sorting protein 4a
Length = 437
Score = 184 bits (467), Expect = 1e-46
Identities = 92/150 (61%), Positives = 113/150 (75%)
Frame = +3
Query: 3 RIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDALMVP 182
RIYI LPE ARA+MF+L +G+ P H+LT N EL +EGYSGADISI VRD+LM P
Sbjct: 288 RIYIPLPEEAARAQMFRLHLGSTP--HNLTDANIHELARKTEGYSGADISIIVRDSLMQP 345
Query: 183 VRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPCVTFA 362
VRKVQ+ATHF++V GPS T+PSV++ DLLTPCSPG PGAIEM W V +KLLEP V +
Sbjct: 346 VRKVQSATHFKKVCGPSRTNPSVMIDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVCMS 405
Query: 363 DMKLALSRNKPTVNQKDLEKLIQFTTDFGQ 452
DM +L+ +PTVN DL K+ +F+ DFGQ
Sbjct: 406 DMLRSLATTRPTVNADDLLKVKKFSEDFGQ 435
>sp|Q9UN37|VPS4A_HUMAN Vacuolar sorting protein 4a (SKD2 protein) (hVPS4) (VPS4-1)
Length = 437
Score = 182 bits (461), Expect = 6e-46
Identities = 90/150 (60%), Positives = 113/150 (75%)
Frame = +3
Query: 3 RIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDALMVP 182
RIYI LPE ARA+MF+L +G+ P H+LT N EL +EGYSGADISI VRD+LM P
Sbjct: 288 RIYIPLPEEAARAQMFRLHLGSTP--HNLTDANIHELARKTEGYSGADISIIVRDSLMQP 345
Query: 183 VRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPCVTFA 362
VRKVQ+ATHF++V GPS T+PS+++ DLLTPCSPG PGA+EM W V +KLLEP V +
Sbjct: 346 VRKVQSATHFKKVCGPSRTNPSMMIDDLLTPCSPGDPGAMEMTWMDVPGDKLLEPVVCMS 405
Query: 363 DMKLALSRNKPTVNQKDLEKLIQFTTDFGQ 452
DM +L+ +PTVN DL K+ +F+ DFGQ
Sbjct: 406 DMLRSLATTRPTVNADDLLKVKKFSEDFGQ 435
>sp|Q09803|VPS4_SCHPO Suppressor protein of bem1/bed5 double mutants
Length = 432
Score = 141 bits (355), Expect = 1e-33
Identities = 74/149 (49%), Positives = 97/149 (65%)
Frame = +3
Query: 3 RIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDALMVP 182
RIYI LP A ARA MF+L++G P + LT Q+F EL +++GYSG+DISI VRDA+M P
Sbjct: 289 RIYIPLPNAHARARMFELNVGKIPSE--LTSQDFKELAKMTDGYSGSDISIVVRDAIMEP 346
Query: 183 VRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPCVTFA 362
VR++ TATHF+ V L+TPCSPG P A E +W V+ E ++EP +T
Sbjct: 347 VRRIHTATHFKEVYDNKSN------RTLVTPCSPGDPDAFESSWLEVNPEDIMEPKLTVR 400
Query: 363 DMKLALSRNKPTVNQKDLEKLIQFTTDFG 449
D A+ + KPT+N D+EK QFT DFG
Sbjct: 401 DFYSAVRKVKPTLNAGDIEKHTQFTKDFG 429
>sp|P52917|VPS4_YEAST Vacuolar protein sorting-associated protein VPS4 (END13 protein)
(DOA4-independent degradation protein 6)
Length = 437
Score = 138 bits (348), Expect = 8e-33
Identities = 72/150 (48%), Positives = 102/150 (68%)
Frame = +3
Query: 3 RIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDALMVP 182
RIYI LP+ AR MF++++G+ P LT +++ LG ++EGYSG+DI++ V+DALM P
Sbjct: 293 RIYIPLPDLAARTTMFEINVGDTPCV--LTKEDYRTLGAMTEGYSGSDIAVVVKDALMQP 350
Query: 183 VRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPCVTFA 362
+RK+Q+ATHF+ V S D + LTPCSPG GAIEM+W +++++L EP +T
Sbjct: 351 IRKIQSATHFKDV---STEDDE---TRKLTPCSPGDDGAIEMSWTDIEADELKEPDLTIK 404
Query: 363 DMKLALSRNKPTVNQKDLEKLIQFTTDFGQ 452
D A+ +PTVN+ DL K QFT DFGQ
Sbjct: 405 DFLKAIKSTRPTVNEDDLLKQEQFTRDFGQ 434
>sp|Q5XIK7|KATL1_RAT Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit
A-like 1) (p60 katanin-like 1)
Length = 488
Score = 58.9 bits (141), Expect = 8e-09
Identities = 45/149 (30%), Positives = 71/149 (47%)
Frame = +3
Query: 3 RIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDALMVP 182
RIYI LP A RAE+ K+S+ D+ + ++ +EGYSGADI+ RDA ++
Sbjct: 373 RIYIPLPTAKGRAELLKISLREVELDPDI---HLEDIAEKTEGYSGADITNICRDASLMA 429
Query: 183 VRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPCVTFA 362
+R RR+ G SP + + S++ L+ VT
Sbjct: 430 MR--------RRINGLSPEEIRAL------------------------SKEELQMPVTRG 457
Query: 363 DMKLALSRNKPTVNQKDLEKLIQFTTDFG 449
D++LAL + +V+ DLEK ++ +FG
Sbjct: 458 DLELALKKIAKSVSAADLEKYEKWMVEFG 486
>sp|Q8K0T4|KATL1_MOUSE Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit
A-like 1) (p60 katanin-like 1)
Length = 488
Score = 58.2 bits (139), Expect = 1e-08
Identities = 45/149 (30%), Positives = 71/149 (47%)
Frame = +3
Query: 3 RIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDALMVP 182
RIYI LP A RAE+ K+S+ D+ + ++ +EGYSGADI+ RDA ++
Sbjct: 373 RIYIPLPTAKGRAELLKISLREVELDPDV---HLEDIADKTEGYSGADITNICRDASLMA 429
Query: 183 VRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPCVTFA 362
+R RR+ G SP + + S++ L+ VT
Sbjct: 430 MR--------RRINGLSPEEIRAL------------------------SKEELQMPVTRG 457
Query: 363 DMKLALSRNKPTVNQKDLEKLIQFTTDFG 449
D++LAL + +V+ DLEK ++ +FG
Sbjct: 458 DLELALKKIAKSVSAADLEKYEKWMVEFG 486
>sp|Q9BW62|KATL1_HUMAN Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit
A-like 1) (p60 katanin-like 1)
Length = 490
Score = 56.2 bits (134), Expect = 5e-08
Identities = 45/149 (30%), Positives = 70/149 (46%)
Frame = +3
Query: 3 RIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDALMVP 182
RIYI LP A RAE+ K+++ D+ ++ +E EGYSGADI+ RDA ++
Sbjct: 375 RIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAEK---IEGYSGADITNVCRDASLMA 431
Query: 183 VRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPCVTFA 362
+R RR+ G SP + + S++ L+ VT
Sbjct: 432 MR--------RRINGLSPEEIRAL------------------------SKEELQMPVTKG 459
Query: 363 DMKLALSRNKPTVNQKDLEKLIQFTTDFG 449
D +LAL + +V+ DLEK ++ +FG
Sbjct: 460 DFELALKKIAKSVSAADLEKYEKWMVEFG 488
>sp|O61577|KTNA1_STRPU Katanin p60 ATPase-containing subunit (Katanin p60 subunit) (p60
katanin)
Length = 516
Score = 52.0 bits (123), Expect = 1e-06
Identities = 42/149 (28%), Positives = 70/149 (46%)
Frame = +3
Query: 3 RIYIALPEAGARAEMFKLSMGNKPGQHDLTPQNFSELGHLSEGYSGADISIAVRDALMVP 182
RIYI LPE R ++ ++++ P D+ ++ +E +GYSGADI+ RDA M+
Sbjct: 401 RIYIPLPEIDGREQLLRINLKEVPLADDIDLKSIAEK---MDGYSGADITNVCRDASMMA 457
Query: 183 VRKVQTATHFRRVRGPSPTDPSVIVSDLLTPCSPGSPGAIEMNWQTVDSEKLLEPCVTFA 362
+R RR++G P + + + E+L +P T A
Sbjct: 458 MR--------RRIQGLRPEE-----------------------IRHIPKEELNQPS-TPA 485
Query: 363 DMKLALSRNKPTVNQKDLEKLIQFTTDFG 449
D LAL + +V ++DL K + + +FG
Sbjct: 486 DFLLALQKVSKSVGKEDLVKYMAWMEEFG 514
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,407,025
Number of Sequences: 369166
Number of extensions: 1440094
Number of successful extensions: 4851
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4527
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4813
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3931403200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)