Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00478 (1757 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P38607|VATA2_HUMAN Vacuolar ATP synthase catalytic subun... 917 0.0 sp|Q27331|VATA2_DROME Vacuolar ATP synthase catalytic subun... 915 0.0 sp|P31400|VATA_MANSE Vacuolar ATP synthase catalytic subuni... 910 0.0 sp|P38606|VATA1_HUMAN Vacuolar ATP synthase catalytic subun... 904 0.0 sp|P31404|VATA1_BOVIN Vacuolar ATP synthase catalytic subun... 898 0.0 sp|P48602|VATA1_DROME Vacuolar ATP synthase catalytic subun... 895 0.0 sp|Q29048|VATA1_PIG Vacuolar ATP synthase catalytic subunit... 895 0.0 sp|P50516|VATA1_MOUSE Vacuolar ATP synthase catalytic subun... 894 0.0 sp|O16109|VATA_AEDAE Vacuolar ATP synthase catalytic subuni... 857 0.0 sp|P13548|VATA_PHAAU Vacuolar ATP synthase catalytic subuni... 767 0.0
>sp|P38607|VATA2_HUMAN Vacuolar ATP synthase catalytic subunit A, osteoclast isoform (V-ATPase A subunit 2) (Vacuolar proton pump alpha subunit 2) (V-ATPase 69 kDa subunit 2) (Isoform HO68) Length = 615 Score = 917 bits (2370), Expect = 0.0 Identities = 453/572 (79%), Positives = 512/572 (89%) Frame = +2 Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181 GY +LVGEIIRLEGD ATIQVYEDTSGVTVGDPV++TGKPLSVELGPGIM SIFDGIQRP Sbjct: 45 GYYELVGEIIRLEGDMATIQVYEDTSGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRP 104 Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPVNVSSGMHVSGGDVFGIVQENTLVKHKI 361 LK I S SIYIP+GVNVPAL+R+ +WDF PV+V G H++GGD++G+V ENTLVKHK+ Sbjct: 105 LKDINELSNSIYIPKGVNVPALSRTAQWDFSPVSVKVGSHITGGDLYGLVHENTLVKHKL 164 Query: 362 MVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANYP 541 ++ P+ KG V +IA GNYTVD+ VL TEF+ ++K TM +KLPANYP Sbjct: 165 LLPPRAKGTVTYIAEPGNYTVDDVVLETEFDGERSKFTMLQVWPVRQPRPVTEKLPANYP 224 Query: 542 LLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMSE 721 LLTGQRVLD+LFPCVQGGTTAIPGAFGCGKTVISQSLSK+SNSDVIIYVGCGERGNEMSE Sbjct: 225 LLTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSE 284 Query: 722 VLQDFPQLTVEIDGRNESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSM 901 VL+DFPQL++EIDG ESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSM Sbjct: 285 VLRDFPQLSLEIDGVTESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSM 344 Query: 902 MADSTSRWAEALREISGRLAEMPAESGYPAYLGARLASFYERAGRVQCIGGPDERQGSVT 1081 MADSTSRWAEALREISGRLAEMPA+SGYPAYLGARLASFYERAGRV+C+G PD R+GSV+ Sbjct: 345 MADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPD-REGSVS 403 Query: 1082 IVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISHSKYTRALDDFY 1261 IVGAVSPPGGDFSDPVT+ATLGIVQVFWGLDKKLAQRKHFPSINWLIS+SKY RALDDFY Sbjct: 404 IVGAVSPPGGDFSDPVTTATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYMRALDDFY 463 Query: 1262 DKHYNEFVALRTKTSEILQEEEDLSEIVQLVGKGSLAESDKITLEVARLIKDDFLQQNGY 1441 DK++ EFV LRTK EILQEEEDLSEIVQLVGK SLAE+DKITLEVA+L+KDDFLQQN Y Sbjct: 464 DKNFPEFVPLRTKVKEILQEEEDLSEIVQLVGKASLAETDKITLEVAKLLKDDFLQQNSY 523 Query: 1442 SSYDKFCPFYKTVGMLKNMIHFYDQARHAVETTSQSDSKITWSMIREAMNDTIYKISSMK 1621 S YD+FCPFYKTVGMLKNMI FYD +RHAVE+T+QS++KITW++IR++M + +Y++SSMK Sbjct: 524 SPYDRFCPFYKTVGMLKNMIAFYDMSRHAVESTAQSENKITWNVIRDSMGNILYQLSSMK 583 Query: 1622 FKDPVKDGKEKILHDFDELYEEISNGFRNLED 1717 FKDPVKDG+ KI DF++L+E+I FRNLED Sbjct: 584 FKDPVKDGEAKIKADFEQLHEDIQQAFRNLED 615
>sp|Q27331|VATA2_DROME Vacuolar ATP synthase catalytic subunit A isoform 2 (V-ATPase A subunit 2) (Vacuolar proton pump alpha subunit 2) (V-ATPase 69 kDa subunit 2) Length = 614 Score = 915 bits (2365), Expect = 0.0 Identities = 450/572 (78%), Positives = 513/572 (89%) Frame = +2 Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181 GY +LVGEIIRLEGD ATIQVYE+TSGVTVGDPV++TGKPLSVELGPGIM SIFDGIQRP Sbjct: 44 GYYELVGEIIRLEGDMATIQVYEETSGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRP 103 Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPVNVSSGMHVSGGDVFGIVQENTLVKHKI 361 LK I ++SIYIP+GVNVP+L+R W+F P+NV G H++GGD++G+V ENTLVKHK+ Sbjct: 104 LKDINELTESIYIPKGVNVPSLSRVASWEFNPLNVKVGSHITGGDLYGLVHENTLVKHKM 163 Query: 362 MVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANYP 541 +V+P+ KG V++IAP GNY VD+ VL TEF+ TKHTM +KLPAN+P Sbjct: 164 IVNPRAKGTVRYIAPSGNYKVDDVVLETEFDGEITKHTMLQVWPVRHHAPVTEKLPANHP 223 Query: 542 LLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMSE 721 LLTGQRVLD+LFPCVQGGTTAIPGAFGCGKTVISQ+LSK+SNSDVIIYVGCGERGNEMSE Sbjct: 224 LLTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQALSKYSNSDVIIYVGCGERGNEMSE 283 Query: 722 VLQDFPQLTVEIDGRNESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSM 901 VL+DFP+L+VEIDG ESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSM Sbjct: 284 VLRDFPELSVEIDGVTESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSM 343 Query: 902 MADSTSRWAEALREISGRLAEMPAESGYPAYLGARLASFYERAGRVQCIGGPDERQGSVT 1081 MADSTSRWAEALREISGRLAEMP +SGYPAYLGARLASFYERAGRV+C+G P ER+GSV+ Sbjct: 344 MADSTSRWAEALREISGRLAEMPRDSGYPAYLGARLASFYERAGRVKCLGNP-EREGSVS 402 Query: 1082 IVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISHSKYTRALDDFY 1261 IVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLIS+SKY RALDDFY Sbjct: 403 IVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYMRALDDFY 462 Query: 1262 DKHYNEFVALRTKTSEILQEEEDLSEIVQLVGKGSLAESDKITLEVARLIKDDFLQQNGY 1441 DK++ EFV LRTK EILQEEEDLSEIVQLVGK SLAE+DKITLEVA+L+KDDFLQQN Y Sbjct: 463 DKNFPEFVPLRTKVKEILQEEEDLSEIVQLVGKASLAETDKITLEVAKLLKDDFLQQNSY 522 Query: 1442 SSYDKFCPFYKTVGMLKNMIHFYDQARHAVETTSQSDSKITWSMIREAMNDTIYKISSMK 1621 SSYD+FCPFYKTVGML+N+I FYD ARH+VE+T+QS++KITW++IREAM + +Y++SSMK Sbjct: 523 SSYDRFCPFYKTVGMLRNIIDFYDMARHSVESTAQSENKITWNVIREAMGNIMYQLSSMK 582 Query: 1622 FKDPVKDGKEKILHDFDELYEEISNGFRNLED 1717 FKDPVKDG+ KI DF++L+E++ FRNLED Sbjct: 583 FKDPVKDGEAKIKADFEQLHEDLQQAFRNLED 614
>sp|P31400|VATA_MANSE Vacuolar ATP synthase catalytic subunit A (V-ATPase A subunit) (Vacuolar proton pump alpha subunit) (V-ATPase 69 kDa subunit) Length = 617 Score = 910 bits (2353), Expect = 0.0 Identities = 447/572 (78%), Positives = 511/572 (89%) Frame = +2 Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181 GY +LVGEIIRLEGD ATIQVYE+TSGVTVGDPV++TGKPLSVELGPGI+ SIFDGIQRP Sbjct: 47 GYNELVGEIIRLEGDMATIQVYEETSGVTVGDPVLRTGKPLSVELGPGILGSIFDGIQRP 106 Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPVNVSSGMHVSGGDVFGIVQENTLVKHKI 361 LK I ++SIYIP+GVNVP+L R + W+F P+NV G H++GGD++GIV ENTLVKHK+ Sbjct: 107 LKDINELTQSIYIPKGVNVPSLAREVDWEFNPLNVKVGSHITGGDLYGIVHENTLVKHKM 166 Query: 362 MVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANYP 541 ++ P+ KG V +IAP GNY V + VL TEF+ + ++TM +KLPAN+P Sbjct: 167 LMPPRAKGTVTYIAPAGNYKVTDVVLETEFDGEKAQYTMLQVWPVRQPRPVTEKLPANHP 226 Query: 542 LLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMSE 721 LLTGQRVLD+LFPCVQGGTTAIPGAFGCGKTVISQ+LSK+SNSDVIIYVGCGERGNEMSE Sbjct: 227 LLTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQALSKYSNSDVIIYVGCGERGNEMSE 286 Query: 722 VLQDFPQLTVEIDGRNESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSM 901 VL+DFP+LTVEI+G ESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSM Sbjct: 287 VLRDFPELTVEIEGVTESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSM 346 Query: 902 MADSTSRWAEALREISGRLAEMPAESGYPAYLGARLASFYERAGRVQCIGGPDERQGSVT 1081 MADSTSRWAEALREISGRLAEMPA+SGYPAYLGARLASFYERAGRV+C+G PD R+GSV+ Sbjct: 347 MADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPD-REGSVS 405 Query: 1082 IVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISHSKYTRALDDFY 1261 IVGAVSPPGGDFSDPVT+ATLGIVQVFWGLDKKLAQRKHFPSINWLIS+SKY RALDDFY Sbjct: 406 IVGAVSPPGGDFSDPVTAATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYMRALDDFY 465 Query: 1262 DKHYNEFVALRTKTSEILQEEEDLSEIVQLVGKGSLAESDKITLEVARLIKDDFLQQNGY 1441 +K+Y EFV LRTK EILQEEEDLSEIVQLVGK SLAE+DKITLEVA+L+KDDFLQQN Y Sbjct: 466 EKNYPEFVPLRTKVKEILQEEEDLSEIVQLVGKASLAETDKITLEVAKLLKDDFLQQNSY 525 Query: 1442 SSYDKFCPFYKTVGMLKNMIHFYDQARHAVETTSQSDSKITWSMIREAMNDTIYKISSMK 1621 SSYD+FCPFYKTVGMLKN+I FYD +RHAVE+T+QSD+K+TW++IR+AM + +Y++SSMK Sbjct: 526 SSYDRFCPFYKTVGMLKNIISFYDMSRHAVESTAQSDNKVTWNVIRDAMGNVLYQLSSMK 585 Query: 1622 FKDPVKDGKEKILHDFDELYEEISNGFRNLED 1717 FKDPVKDG+ KI DFD+L E++S FRNLED Sbjct: 586 FKDPVKDGEAKIKADFDQLLEDMSAAFRNLED 617
>sp|P38606|VATA1_HUMAN Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (V-ATPase A subunit 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) (Isoform VA68) Length = 617 Score = 904 bits (2337), Expect = 0.0 Identities = 447/573 (78%), Positives = 507/573 (88%), Gaps = 1/573 (0%) Frame = +2 Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181 G+ +LVGEIIRLEGD ATIQVYE+TSGV+VGDPV++TGKPLSVELGPGIM +IFDGIQRP Sbjct: 46 GHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRP 105 Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPV-NVSSGMHVSGGDVFGIVQENTLVKHK 358 L I+SQ++SIYIPRGVNV AL+R IKWDF P N+ G H++GGD++GIV EN+L+KHK Sbjct: 106 LSDISSQTQSIYIPRGVNVSALSRDIKWDFTPCKNLRVGSHITGGDIYGIVSENSLIKHK 165 Query: 359 IMVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANY 538 IM+ P+ +G V +IAP GNY + VL EF V+ K TM +KLPAN+ Sbjct: 166 IMLPPRNRGTVTYIAPPGNYDTSDVVLELEFEGVKEKFTMVQVWPVRQVRPVTEKLPANH 225 Query: 539 PLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMS 718 PLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSK+SNSDVIIYVGCGERGNEMS Sbjct: 226 PLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMS 285 Query: 719 EVLQDFPQLTVEIDGRNESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVS 898 EVL+DFP+LT+E+DG+ ESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGY+VS Sbjct: 286 EVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVS 345 Query: 899 MMADSTSRWAEALREISGRLAEMPAESGYPAYLGARLASFYERAGRVQCIGGPDERQGSV 1078 MMADSTSRWAEALREISGRLAEMPA+SGYPAYLGARLASFYERAGRV+C+G P ER+GSV Sbjct: 346 MMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNP-EREGSV 404 Query: 1079 TIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISHSKYTRALDDF 1258 +IVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPS+NWLIS+SKY RALD++ Sbjct: 405 SIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEY 464 Query: 1259 YDKHYNEFVALRTKTSEILQEEEDLSEIVQLVGKGSLAESDKITLEVARLIKDDFLQQNG 1438 YDKH+ EFV LRTK EILQEEEDL+EIVQLVGK SLAE+DKITLEVA+LIKDDFLQQNG Sbjct: 465 YDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNG 524 Query: 1439 YSSYDKFCPFYKTVGMLKNMIHFYDQARHAVETTSQSDSKITWSMIREAMNDTIYKISSM 1618 Y+ YD+FCPFYKTVGML NMI FYD AR AVETT+QSD+KITWS+IRE M D +YK+SSM Sbjct: 525 YTPYDRFCPFYKTVGMLSNMIAFYDMARRAVETTAQSDNKITWSIIREHMGDILYKLSSM 584 Query: 1619 KFKDPVKDGKEKILHDFDELYEEISNGFRNLED 1717 KFKDP+KDG+ KI D+ +L E++ N FR+LED Sbjct: 585 KFKDPLKDGEAKIKSDYAQLLEDMQNAFRSLED 617
>sp|P31404|VATA1_BOVIN Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (V-ATPase A subunit 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) Length = 617 Score = 898 bits (2320), Expect = 0.0 Identities = 443/573 (77%), Positives = 506/573 (88%), Gaps = 1/573 (0%) Frame = +2 Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181 G+ +LVGEIIRLEGD ATIQVYE+TSGV+VGDPV++TGKPLSVEL PGIM +IFDGIQRP Sbjct: 46 GHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELCPGIMGAIFDGIQRP 105 Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPV-NVSSGMHVSGGDVFGIVQENTLVKHK 358 L I+SQ++SIYIPRGVNV AL+R +KWDF P N+ G H++GGD++GIV EN+L+KHK Sbjct: 106 LSDISSQTQSIYIPRGVNVSALSRDVKWDFTPCKNLRVGSHITGGDIYGIVNENSLIKHK 165 Query: 359 IMVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANY 538 IM+ P+ +G V +IAP GNY + VL EF ++ K +M +KLPAN+ Sbjct: 166 IMLPPRNRGTVTYIAPPGNYDTSDVVLELEFEGIKEKFSMVQVWPVRQVRPVTEKLPANH 225 Query: 539 PLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMS 718 PLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSK+SNSDVIIYVGCGERGNEMS Sbjct: 226 PLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMS 285 Query: 719 EVLQDFPQLTVEIDGRNESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVS 898 EVL+DFP+LT+E+DG+ ESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGY+VS Sbjct: 286 EVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVS 345 Query: 899 MMADSTSRWAEALREISGRLAEMPAESGYPAYLGARLASFYERAGRVQCIGGPDERQGSV 1078 MMADSTSRWAEALREISGRLAEMPA+SGYPAYLGARLASFYERAGRV+C+G P ER+GSV Sbjct: 346 MMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNP-EREGSV 404 Query: 1079 TIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISHSKYTRALDDF 1258 +IVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPS+NWLIS+SKY RALD++ Sbjct: 405 SIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEY 464 Query: 1259 YDKHYNEFVALRTKTSEILQEEEDLSEIVQLVGKGSLAESDKITLEVARLIKDDFLQQNG 1438 YDKH+ EFV LRTK EILQEEEDL+EIVQLVGK SLAE+DKITLEVA+LIKDDFLQQNG Sbjct: 465 YDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNG 524 Query: 1439 YSSYDKFCPFYKTVGMLKNMIHFYDQARHAVETTSQSDSKITWSMIREAMNDTIYKISSM 1618 Y+ YD+FCPFYKTVGML NMI FYD AR AVETT+QSD+KITWS+IRE M + +YK+SSM Sbjct: 525 YTPYDRFCPFYKTVGMLSNMIAFYDMARRAVETTAQSDNKITWSIIREHMGEILYKLSSM 584 Query: 1619 KFKDPVKDGKEKILHDFDELYEEISNGFRNLED 1717 KFKDPVKDG+ KI D+ +L E++ N FR+LED Sbjct: 585 KFKDPVKDGEAKIKADYAQLLEDMQNAFRSLED 617
>sp|P48602|VATA1_DROME Vacuolar ATP synthase catalytic subunit A isoform 1 (V-ATPase A subunit 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) Length = 614 Score = 895 bits (2314), Expect = 0.0 Identities = 439/572 (76%), Positives = 505/572 (88%) Frame = +2 Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181 GY +LVGEIIRLEGD ATIQVYE+TSGVTVGDPV++TGKPLSVELGPGIM SIFDGIQRP Sbjct: 44 GYYELVGEIIRLEGDMATIQVYEETSGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRP 103 Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPVNVSSGMHVSGGDVFGIVQENTLVKHKI 361 L+ I + SIYIP+GVN AL+RS W+F P+NV G H++GGD++G+V ENTLVK ++ Sbjct: 104 LRDIGVMTNSIYIPKGVNTTALSRSEMWEFNPLNVRVGSHITGGDLYGVVHENTLVKQRM 163 Query: 362 MVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANYP 541 +V P+ KG V++IAP GNY +++ VL TEF+ TKHTM +KLPAN+P Sbjct: 164 IVAPRAKGTVRYIAPAGNYNLEDIVLETEFDGEITKHTMLQVWPVRQPRPVTEKLPANHP 223 Query: 542 LLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMSE 721 L TGQRVLD+LFPCVQGGTTAIPGAFGCGKTVISQ+LSK+SNSDVIIYVGCGERGNEMSE Sbjct: 224 LFTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQALSKYSNSDVIIYVGCGERGNEMSE 283 Query: 722 VLQDFPQLTVEIDGRNESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSM 901 VL+DFP+LT EIDG ESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNV+M Sbjct: 284 VLRDFPELTCEIDGVTESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVAM 343 Query: 902 MADSTSRWAEALREISGRLAEMPAESGYPAYLGARLASFYERAGRVQCIGGPDERQGSVT 1081 MADSTSRWAEALREISGRLAEMPA+SGYPAYLGARLA+FYERAGRV+C+G P ER+GSV+ Sbjct: 344 MADSTSRWAEALREISGRLAEMPADSGYPAYLGARLATFYERAGRVKCLGNP-EREGSVS 402 Query: 1082 IVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISHSKYTRALDDFY 1261 IVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLIS+SKY RALD++Y Sbjct: 403 IVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYMRALDEYY 462 Query: 1262 DKHYNEFVALRTKTSEILQEEEDLSEIVQLVGKGSLAESDKITLEVARLIKDDFLQQNGY 1441 DK+Y EFV LRTK EILQEEEDLSEIVQLVGK SLAE+DK+TLEVA+L+KDDFLQQN Y Sbjct: 463 DKNYPEFVPLRTKVKEILQEEEDLSEIVQLVGKASLAETDKVTLEVAKLLKDDFLQQNSY 522 Query: 1442 SSYDKFCPFYKTVGMLKNMIHFYDQARHAVETTSQSDSKITWSMIREAMNDTIYKISSMK 1621 S YD+ CPFYKTVGML+N++ FY+ ARHAVE+T+QSD+KITW+ IRE+M +Y++SSMK Sbjct: 523 SPYDRVCPFYKTVGMLRNIMAFYETARHAVESTAQSDNKITWNTIRESMGGIMYQLSSMK 582 Query: 1622 FKDPVKDGKEKILHDFDELYEEISNGFRNLED 1717 FKDPVKDG++KI D+D+LYE++ FRNLED Sbjct: 583 FKDPVKDGEQKIKADYDQLYEDLQQAFRNLED 614
>sp|Q29048|VATA1_PIG Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (V-ATPase A subunit 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) Length = 617 Score = 895 bits (2312), Expect = 0.0 Identities = 442/573 (77%), Positives = 506/573 (88%), Gaps = 1/573 (0%) Frame = +2 Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181 G+ +LVGEIIRLEGD ATIQVYE+TSGV+VGDPV++TGKPLSVELGPGIM +IFDGIQRP Sbjct: 46 GHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRP 105 Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPV-NVSSGMHVSGGDVFGIVQENTLVKHK 358 L I+SQ++SIYIPRGVNV AL+R +KW+F P N+ G H++GGD++GIV EN+L+KH+ Sbjct: 106 LSDISSQTQSIYIPRGVNVSALSRDVKWEFTPSKNLRVGSHITGGDIYGIVNENSLIKHR 165 Query: 359 IMVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANY 538 IM+ P+ +G V +IAP GNY + VL EF V+ K +M +KLPAN+ Sbjct: 166 IMLPPRNRGTVTYIAPPGNYDTSDVVLELEFEGVKEKFSMVQVWPVRQVRPVTEKLPANH 225 Query: 539 PLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMS 718 PLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSK+SNSDVIIYVGCGER NEMS Sbjct: 226 PLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERVNEMS 285 Query: 719 EVLQDFPQLTVEIDGRNESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVS 898 EVL+DFP+LT+E+DG+ ESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGY+VS Sbjct: 286 EVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVS 345 Query: 899 MMADSTSRWAEALREISGRLAEMPAESGYPAYLGARLASFYERAGRVQCIGGPDERQGSV 1078 MMA+STSRWAEALREISGRLAEMPA+SGYPAYLGARLASFYERAGRV+C+G P ER+GSV Sbjct: 346 MMANSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNP-EREGSV 404 Query: 1079 TIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISHSKYTRALDDF 1258 TIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPS+NWLIS+SKY RALD++ Sbjct: 405 TIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEY 464 Query: 1259 YDKHYNEFVALRTKTSEILQEEEDLSEIVQLVGKGSLAESDKITLEVARLIKDDFLQQNG 1438 YDKH+ EFV LRTK EILQEEEDL+EIVQLVGK SLAE+DKITLEVA+LIKDDFLQQNG Sbjct: 465 YDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNG 524 Query: 1439 YSSYDKFCPFYKTVGMLKNMIHFYDQARHAVETTSQSDSKITWSMIREAMNDTIYKISSM 1618 Y+ YD+FCPFYKTVGML NMI FYD AR AVETT+QSD+KITWS+IRE M + +YK+SSM Sbjct: 525 YTPYDRFCPFYKTVGMLSNMIAFYDLARRAVETTAQSDNKITWSIIREHMGEILYKLSSM 584 Query: 1619 KFKDPVKDGKEKILHDFDELYEEISNGFRNLED 1717 KFKDPVKDG+ KI D+ +L E++ N FR+LED Sbjct: 585 KFKDPVKDGEAKIKADYAQLLEDVQNAFRSLED 617
>sp|P50516|VATA1_MOUSE Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (V-ATPase A subunit 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) Length = 617 Score = 894 bits (2310), Expect = 0.0 Identities = 443/573 (77%), Positives = 504/573 (87%), Gaps = 1/573 (0%) Frame = +2 Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181 G+ +LVGEIIRLEGD ATIQVYE+TSGV+VGDPV++TGKP SVELGPGIM +IFDGIQRP Sbjct: 46 GHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPRSVELGPGIMGAIFDGIQRP 105 Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPV-NVSSGMHVSGGDVFGIVQENTLVKHK 358 L I+SQ++SIYIPRGVNV AL+R IKW+F P N+ G H++GGD++GIV EN+L+KHK Sbjct: 106 LSDISSQTQSIYIPRGVNVSALSRDIKWEFIPSKNLRVGSHITGGDIYGIVNENSLIKHK 165 Query: 359 IMVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANY 538 IM+ P+ +G V +IAP GNY VL EF V+ K +M +KLPAN+ Sbjct: 166 IMLPPRNRGSVTYIAPPGNYDASNVVLELEFEGVKEKFSMVQVWPVRQVRPVTEKLPANH 225 Query: 539 PLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMS 718 PLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSK+SNSDVIIYVGCGERGNEMS Sbjct: 226 PLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMS 285 Query: 719 EVLQDFPQLTVEIDGRNESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVS 898 EVL+DFP+LT+E+DG+ ESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGY+VS Sbjct: 286 EVLRDFPELTMEVDGKAESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVS 345 Query: 899 MMADSTSRWAEALREISGRLAEMPAESGYPAYLGARLASFYERAGRVQCIGGPDERQGSV 1078 MMADSTSRWAEALREISGRLAEMPA+SGYPAYLGARLASFYERAGRV+C+G P ER+GSV Sbjct: 346 MMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNP-EREGSV 404 Query: 1079 TIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISHSKYTRALDDF 1258 +IVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPS+NWLIS+SKY RALD++ Sbjct: 405 SIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEY 464 Query: 1259 YDKHYNEFVALRTKTSEILQEEEDLSEIVQLVGKGSLAESDKITLEVARLIKDDFLQQNG 1438 YDKH+ EFV LRTK EILQEE DL+EIVQLVGK SLAE+DKITLEVA+LIKDDFLQQNG Sbjct: 465 YDKHFTEFVPLRTKAKEILQEEGDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNG 524 Query: 1439 YSSYDKFCPFYKTVGMLKNMIHFYDQARHAVETTSQSDSKITWSMIREAMNDTIYKISSM 1618 Y+ YD+FCPFYKTVGML NMI FYD AR AVETT+QSD+KITWS+IRE M + +YK+SSM Sbjct: 525 YTPYDRFCPFYKTVGMLSNMISFYDMARRAVETTAQSDNKITWSIIREHMGEILYKLSSM 584 Query: 1619 KFKDPVKDGKEKILHDFDELYEEISNGFRNLED 1717 KFKDPVKDG+ KI D+ +L E++ N FR+LED Sbjct: 585 KFKDPVKDGEAKIKADYAQLLEDMQNAFRSLED 617
>sp|O16109|VATA_AEDAE Vacuolar ATP synthase catalytic subunit A (V-ATPase A subunit) (Vacuolar proton pump alpha subunit) (V-ATPase 69 kDa subunit) Length = 615 Score = 857 bits (2214), Expect = 0.0 Identities = 435/574 (75%), Positives = 493/574 (85%), Gaps = 2/574 (0%) Frame = +2 Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181 GY +LVGEIIRLEGD ATIQVYE+TSGVTVGDPV++TGKPLSVELGPGIM SIFDGIQRP Sbjct: 44 GYYELVGEIIRLEGDMATIQVYEETSGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRP 103 Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPVNVSS-GMHVSGGDVFGIVQENTLVKHK 358 LK I + SIYIP G L + QP+ G H++G D++G+V ENTLVKHK Sbjct: 104 LKDINELTSSIYIPEGCEHSLLVPYRRLGIQPLERKGLGSHITGRDLYGLVHENTLVKHK 163 Query: 359 IMVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANY 538 ++V P+ KG V++IAP GNYTVD+ +L TEF+ K +M +KLPAN+ Sbjct: 164 LLVPPRAKGTVRYIAPPGNYTVDDIILETEFDGEINKWSMLQVWPVRQPRPVTEKLPANH 223 Query: 539 PLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMS 718 PLLTGQRVLD+LFPCVQGGTTAIPGAFGCGKTVISQ+LSK+SNSDVIIYVGCGERGNEMS Sbjct: 224 PLLTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQALSKYSNSDVIIYVGCGERGNEMS 283 Query: 719 EVLQDFPQLTVEIDGRNESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVS 898 EVL+DFP+L+VEIDG ESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVS Sbjct: 284 EVLRDFPELSVEIDGVTESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVS 343 Query: 899 MMADSTSRWAEALREISGRLAEMPAESGYPAYLGARLASFYERAGRVQCIGGPDERQGSV 1078 MMADSTSRWAEALREISGRLAEMPA+SGYPAYLGARLASFYERAGRV+C+G P ER+GSV Sbjct: 344 MMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNP-EREGSV 402 Query: 1079 TIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISHSKYTRALDDF 1258 +IVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLIS+SKY RALDDF Sbjct: 403 SIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYMRALDDF 462 Query: 1259 YDKHYNEFVALRTKTSEILQEEEDLSEIVQLVGKGSLAESDKITLEVARLIKDDFLQQNG 1438 YDK++ EFV K EILQEEEDLSEIVQLVGK SLAE+DKITLEVA+L+KDDFLQQN Sbjct: 463 YDKNFQEFVPTAYKVKEILQEEEDLSEIVQLVGKASLAETDKITLEVAKLLKDDFLQQNS 522 Query: 1439 YSSYDKFCPFYKTVG-MLKNMIHFYDQARHAVETTSQSDSKITWSMIREAMNDTIYKISS 1615 YS+YD+FCPFYKTVG ML+NMI FYD ARHAVETT+QS++KITW++IR++M + +Y++SS Sbjct: 523 YSAYDRFCPFYKTVGRMLRNMIGFYDMARHAVETTAQSENKITWNVIRDSMGNILYQLSS 582 Query: 1616 MKFKDPVKDGKEKILHDFDELYEEISNGFRNLED 1717 MKFKDP + K KI DFD+LYE++ FRNLED Sbjct: 583 MKFKDPGRMAK-KIKADFDQLYEDLQQAFRNLED 615
>sp|P13548|VATA_PHAAU Vacuolar ATP synthase catalytic subunit A (V-ATPase A subunit) (Vacuolar proton pump alpha subunit) (V-ATPase 69 kDa subunit) (VAA3-1) Length = 623 Score = 767 bits (1980), Expect = 0.0 Identities = 382/574 (66%), Positives = 465/574 (81%), Gaps = 2/574 (0%) Frame = +2 Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181 G L+GEIIRLEGD ATIQVYE+T+G+ V DPV++T KPLSVELGPGI+ +IFDGIQRP Sbjct: 49 GRDNLIGEIIRLEGDSATIQVYEETAGLMVNDPVLRTHKPLSVELGPGILGNIFDGIQRP 108 Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPVNVSSGMHVSGGDVFGIVQENTLVKHKI 361 LK IA +S +YIPRGV+VPAL++ W+FQP + G ++GGD++ V ENTL++H I Sbjct: 109 LKTIAKRSGDVYIPRGVSVPALDKDTLWEFQPKKIGEGDLLTGGDLYATVFENTLMQHHI 168 Query: 362 MVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANYP 541 + P G + +IAP G Y++ +TVL EF V+ K TM A KL A+ P Sbjct: 169 ALPPDAMGKITYIAPPGQYSITDTVLELEFQGVKKKFTMLQTWPVRTPRPVASKLAADTP 228 Query: 542 LLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMSE 721 LLTGQRVLDALFP V GGT AIPGAFGCGKTVISQ+LSK+SNSD ++YVGCGERGNEM+E Sbjct: 229 LLTGQRVLDALFPSVLGGTCAIPGAFGCGKTVISQALSKYSNSDAVVYVGCGERGNEMAE 288 Query: 722 VLQDFPQLTVEI-DGRNESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVS 898 VL DFPQLT+ + DGR ES+MKRT LVANTSNMPVAAREASIYTGITL+EYFRDMGYNVS Sbjct: 289 VLMDFPQLTMTLPDGREESVMKRTTLVANTSNMPVAAREASIYTGITLAEYFRDMGYNVS 348 Query: 899 MMADSTSRWAEALREISGRLAEMPAESGYPAYLGARLASFYERAGRVQCIGGPDERQGSV 1078 MMADSTSRWAEALREISGRLAEMPA+SGYPAYL ARLASFYER G+V+C+GGP ER GSV Sbjct: 349 MMADSTSRWAEALREISGRLAEMPADSGYPAYLAARLASFYERPGKVKCLGGP-ERTGSV 407 Query: 1079 TIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISHSKYTRALDDF 1258 TIVGAVSPPGGDFSDPVTSATL IVQVFWGLDKKLAQRKHFPS+NWLIS+SKY+ AL+ F Sbjct: 408 TIVGAVSPPGGDFSDPVTSATLSIVQVFWGLDKKLAQRKHFPSVNWLISYSKYSTALESF 467 Query: 1259 YDKHYNEFVALRTKTSEILQEEEDLSEIVQLVGKGSLAESDKITLEVARLIKDDFLQQNG 1438 Y++ +F+ +RTK E+LQ E+DL+EIVQLVGK +LAE DKITLE A+L+++D+L QN Sbjct: 468 YEQFDPDFINIRTKAREVLQREDDLNEIVQLVGKDALAEGDKITLETAKLLREDYLAQNA 527 Query: 1439 YSSYDKFCPFYKTVGMLKNMIHFYDQARHAVETTSQSD-SKITWSMIREAMNDTIYKISS 1615 ++ YDKFCPFYK+V M++N+IHFY+ A AVE + SD KIT+S+I+ + D Y++ S Sbjct: 528 FTPYDKFCPFYKSVWMMRNIIHFYNLANQAVERGAGSDGQKITYSLIKHRVGDLFYRLVS 587 Query: 1616 MKFKDPVKDGKEKILHDFDELYEEISNGFRNLED 1717 KF+DP +G+ ++ F +L+E++S GFRNLED Sbjct: 588 QKFEDPA-EGEAALVGQFQKLHEDLSTGFRNLED 620
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 217,279,082 Number of Sequences: 369166 Number of extensions: 4881309 Number of successful extensions: 15302 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 13163 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 14405 length of database: 68,354,980 effective HSP length: 116 effective length of database: 46,925,720 effective search space used: 22008162680 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)