Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_A03
(598 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P38607|VATA2_HUMAN Vacuolar ATP synthase catalytic subun... 370 e-102
sp|P50516|VATA1_MOUSE Vacuolar ATP synthase catalytic subun... 369 e-102
sp|O16109|VATA_AEDAE Vacuolar ATP synthase catalytic subuni... 369 e-102
sp|P38606|VATA1_HUMAN Vacuolar ATP synthase catalytic subun... 369 e-102
sp|P31404|VATA1_BOVIN Vacuolar ATP synthase catalytic subun... 369 e-102
sp|P31400|VATA_MANSE Vacuolar ATP synthase catalytic subuni... 369 e-102
sp|Q27331|VATA2_DROME Vacuolar ATP synthase catalytic subun... 367 e-102
sp|P48602|VATA1_DROME Vacuolar ATP synthase catalytic subun... 367 e-101
sp|Q29048|VATA1_PIG Vacuolar ATP synthase catalytic subunit... 365 e-101
sp|Q38677|VATA2_ACEAT Vacuolar ATP synthase catalytic subun... 357 2e-98
>sp|P38607|VATA2_HUMAN Vacuolar ATP synthase catalytic subunit A, osteoclast isoform
(V-ATPase A subunit 2) (Vacuolar proton pump alpha
subunit 2) (V-ATPase 69 kDa subunit 2) (Isoform HO68)
Length = 615
Score = 370 bits (949), Expect = e-102
Identities = 185/199 (92%), Positives = 195/199 (97%)
Frame = +1
Query: 1 AFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMSEVLQDFPQLTVEIDGRNESIMKRTA 180
AFGCGKTVISQSLSK+SNSDVIIYVGCGERGNEMSEVL+DFPQL++EIDG ESIMKRTA
Sbjct: 249 AFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPQLSLEIDGVTESIMKRTA 308
Query: 181 LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPA 360
LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPA
Sbjct: 309 LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPA 368
Query: 361 ESGYPAYLGARLASFYERAGRVQCIGGPDERQGSVTIVGAVSPPGGDFSDPVTSATLGIV 540
+SGYPAYLGARLASFYERAGRV+C+G PD R+GSV+IVGAVSPPGGDFSDPVT+ATLGIV
Sbjct: 369 DSGYPAYLGARLASFYERAGRVKCLGNPD-REGSVSIVGAVSPPGGDFSDPVTTATLGIV 427
Query: 541 QVFWGLDKKLAQRKHFPSI 597
QVFWGLDKKLAQRKHFPSI
Sbjct: 428 QVFWGLDKKLAQRKHFPSI 446
>sp|P50516|VATA1_MOUSE Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform
(V-ATPase A subunit 1) (Vacuolar proton pump alpha
subunit 1) (V-ATPase 69 kDa subunit 1)
Length = 617
Score = 369 bits (948), Expect = e-102
Identities = 183/199 (91%), Positives = 196/199 (98%)
Frame = +1
Query: 1 AFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMSEVLQDFPQLTVEIDGRNESIMKRTA 180
AFGCGKTVISQSLSK+SNSDVIIYVGCGERGNEMSEVL+DFP+LT+E+DG+ ESIMKRTA
Sbjct: 251 AFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKAESIMKRTA 310
Query: 181 LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPA 360
LVANTSNMPVAAREASIYTGITLSEYFRDMGY+VSMMADSTSRWAEALREISGRLAEMPA
Sbjct: 311 LVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPA 370
Query: 361 ESGYPAYLGARLASFYERAGRVQCIGGPDERQGSVTIVGAVSPPGGDFSDPVTSATLGIV 540
+SGYPAYLGARLASFYERAGRV+C+G P ER+GSV+IVGAVSPPGGDFSDPVTSATLGIV
Sbjct: 371 DSGYPAYLGARLASFYERAGRVKCLGNP-EREGSVSIVGAVSPPGGDFSDPVTSATLGIV 429
Query: 541 QVFWGLDKKLAQRKHFPSI 597
QVFWGLDKKLAQRKHFPS+
Sbjct: 430 QVFWGLDKKLAQRKHFPSV 448
>sp|O16109|VATA_AEDAE Vacuolar ATP synthase catalytic subunit A (V-ATPase A subunit)
(Vacuolar proton pump alpha subunit) (V-ATPase 69 kDa
subunit)
Length = 615
Score = 369 bits (948), Expect = e-102
Identities = 185/199 (92%), Positives = 195/199 (97%)
Frame = +1
Query: 1 AFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMSEVLQDFPQLTVEIDGRNESIMKRTA 180
AFGCGKTVISQ+LSK+SNSDVIIYVGCGERGNEMSEVL+DFP+L+VEIDG ESIMKRTA
Sbjct: 249 AFGCGKTVISQALSKYSNSDVIIYVGCGERGNEMSEVLRDFPELSVEIDGVTESIMKRTA 308
Query: 181 LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPA 360
LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPA
Sbjct: 309 LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPA 368
Query: 361 ESGYPAYLGARLASFYERAGRVQCIGGPDERQGSVTIVGAVSPPGGDFSDPVTSATLGIV 540
+SGYPAYLGARLASFYERAGRV+C+G P ER+GSV+IVGAVSPPGGDFSDPVTSATLGIV
Sbjct: 369 DSGYPAYLGARLASFYERAGRVKCLGNP-EREGSVSIVGAVSPPGGDFSDPVTSATLGIV 427
Query: 541 QVFWGLDKKLAQRKHFPSI 597
QVFWGLDKKLAQRKHFPSI
Sbjct: 428 QVFWGLDKKLAQRKHFPSI 446
>sp|P38606|VATA1_HUMAN Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform
(V-ATPase A subunit 1) (Vacuolar proton pump alpha
subunit 1) (V-ATPase 69 kDa subunit 1) (Isoform VA68)
Length = 617
Score = 369 bits (947), Expect = e-102
Identities = 183/199 (91%), Positives = 196/199 (98%)
Frame = +1
Query: 1 AFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMSEVLQDFPQLTVEIDGRNESIMKRTA 180
AFGCGKTVISQSLSK+SNSDVIIYVGCGERGNEMSEVL+DFP+LT+E+DG+ ESIMKRTA
Sbjct: 251 AFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTA 310
Query: 181 LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPA 360
LVANTSNMPVAAREASIYTGITLSEYFRDMGY+VSMMADSTSRWAEALREISGRLAEMPA
Sbjct: 311 LVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPA 370
Query: 361 ESGYPAYLGARLASFYERAGRVQCIGGPDERQGSVTIVGAVSPPGGDFSDPVTSATLGIV 540
+SGYPAYLGARLASFYERAGRV+C+G P ER+GSV+IVGAVSPPGGDFSDPVTSATLGIV
Sbjct: 371 DSGYPAYLGARLASFYERAGRVKCLGNP-EREGSVSIVGAVSPPGGDFSDPVTSATLGIV 429
Query: 541 QVFWGLDKKLAQRKHFPSI 597
QVFWGLDKKLAQRKHFPS+
Sbjct: 430 QVFWGLDKKLAQRKHFPSV 448
>sp|P31404|VATA1_BOVIN Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform
(V-ATPase A subunit 1) (Vacuolar proton pump alpha
subunit 1) (V-ATPase 69 kDa subunit 1)
Length = 617
Score = 369 bits (947), Expect = e-102
Identities = 183/199 (91%), Positives = 196/199 (98%)
Frame = +1
Query: 1 AFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMSEVLQDFPQLTVEIDGRNESIMKRTA 180
AFGCGKTVISQSLSK+SNSDVIIYVGCGERGNEMSEVL+DFP+LT+E+DG+ ESIMKRTA
Sbjct: 251 AFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTA 310
Query: 181 LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPA 360
LVANTSNMPVAAREASIYTGITLSEYFRDMGY+VSMMADSTSRWAEALREISGRLAEMPA
Sbjct: 311 LVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPA 370
Query: 361 ESGYPAYLGARLASFYERAGRVQCIGGPDERQGSVTIVGAVSPPGGDFSDPVTSATLGIV 540
+SGYPAYLGARLASFYERAGRV+C+G P ER+GSV+IVGAVSPPGGDFSDPVTSATLGIV
Sbjct: 371 DSGYPAYLGARLASFYERAGRVKCLGNP-EREGSVSIVGAVSPPGGDFSDPVTSATLGIV 429
Query: 541 QVFWGLDKKLAQRKHFPSI 597
QVFWGLDKKLAQRKHFPS+
Sbjct: 430 QVFWGLDKKLAQRKHFPSV 448
>sp|P31400|VATA_MANSE Vacuolar ATP synthase catalytic subunit A (V-ATPase A subunit)
(Vacuolar proton pump alpha subunit) (V-ATPase 69 kDa
subunit)
Length = 617
Score = 369 bits (946), Expect = e-102
Identities = 184/199 (92%), Positives = 195/199 (97%)
Frame = +1
Query: 1 AFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMSEVLQDFPQLTVEIDGRNESIMKRTA 180
AFGCGKTVISQ+LSK+SNSDVIIYVGCGERGNEMSEVL+DFP+LTVEI+G ESIMKRTA
Sbjct: 251 AFGCGKTVISQALSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTVEIEGVTESIMKRTA 310
Query: 181 LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPA 360
LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPA
Sbjct: 311 LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPA 370
Query: 361 ESGYPAYLGARLASFYERAGRVQCIGGPDERQGSVTIVGAVSPPGGDFSDPVTSATLGIV 540
+SGYPAYLGARLASFYERAGRV+C+G PD R+GSV+IVGAVSPPGGDFSDPVT+ATLGIV
Sbjct: 371 DSGYPAYLGARLASFYERAGRVKCLGNPD-REGSVSIVGAVSPPGGDFSDPVTAATLGIV 429
Query: 541 QVFWGLDKKLAQRKHFPSI 597
QVFWGLDKKLAQRKHFPSI
Sbjct: 430 QVFWGLDKKLAQRKHFPSI 448
>sp|Q27331|VATA2_DROME Vacuolar ATP synthase catalytic subunit A isoform 2 (V-ATPase A
subunit 2) (Vacuolar proton pump alpha subunit 2)
(V-ATPase 69 kDa subunit 2)
Length = 614
Score = 367 bits (943), Expect = e-102
Identities = 184/199 (92%), Positives = 194/199 (97%)
Frame = +1
Query: 1 AFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMSEVLQDFPQLTVEIDGRNESIMKRTA 180
AFGCGKTVISQ+LSK+SNSDVIIYVGCGERGNEMSEVL+DFP+L+VEIDG ESIMKRTA
Sbjct: 248 AFGCGKTVISQALSKYSNSDVIIYVGCGERGNEMSEVLRDFPELSVEIDGVTESIMKRTA 307
Query: 181 LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPA 360
LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMP
Sbjct: 308 LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPR 367
Query: 361 ESGYPAYLGARLASFYERAGRVQCIGGPDERQGSVTIVGAVSPPGGDFSDPVTSATLGIV 540
+SGYPAYLGARLASFYERAGRV+C+G P ER+GSV+IVGAVSPPGGDFSDPVTSATLGIV
Sbjct: 368 DSGYPAYLGARLASFYERAGRVKCLGNP-EREGSVSIVGAVSPPGGDFSDPVTSATLGIV 426
Query: 541 QVFWGLDKKLAQRKHFPSI 597
QVFWGLDKKLAQRKHFPSI
Sbjct: 427 QVFWGLDKKLAQRKHFPSI 445
>sp|P48602|VATA1_DROME Vacuolar ATP synthase catalytic subunit A isoform 1 (V-ATPase A
subunit 1) (Vacuolar proton pump alpha subunit 1)
(V-ATPase 69 kDa subunit 1)
Length = 614
Score = 367 bits (941), Expect = e-101
Identities = 183/199 (91%), Positives = 194/199 (97%)
Frame = +1
Query: 1 AFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMSEVLQDFPQLTVEIDGRNESIMKRTA 180
AFGCGKTVISQ+LSK+SNSDVIIYVGCGERGNEMSEVL+DFP+LT EIDG ESIMKRTA
Sbjct: 248 AFGCGKTVISQALSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTCEIDGVTESIMKRTA 307
Query: 181 LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPA 360
LVANTSNMPVAAREASIYTGITLSEYFRDMGYNV+MMADSTSRWAEALREISGRLAEMPA
Sbjct: 308 LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVAMMADSTSRWAEALREISGRLAEMPA 367
Query: 361 ESGYPAYLGARLASFYERAGRVQCIGGPDERQGSVTIVGAVSPPGGDFSDPVTSATLGIV 540
+SGYPAYLGARLA+FYERAGRV+C+G P ER+GSV+IVGAVSPPGGDFSDPVTSATLGIV
Sbjct: 368 DSGYPAYLGARLATFYERAGRVKCLGNP-EREGSVSIVGAVSPPGGDFSDPVTSATLGIV 426
Query: 541 QVFWGLDKKLAQRKHFPSI 597
QVFWGLDKKLAQRKHFPSI
Sbjct: 427 QVFWGLDKKLAQRKHFPSI 445
>sp|Q29048|VATA1_PIG Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform
(V-ATPase A subunit 1) (Vacuolar proton pump alpha
subunit 1) (V-ATPase 69 kDa subunit 1)
Length = 617
Score = 365 bits (937), Expect = e-101
Identities = 182/199 (91%), Positives = 195/199 (97%)
Frame = +1
Query: 1 AFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMSEVLQDFPQLTVEIDGRNESIMKRTA 180
AFGCGKTVISQSLSK+SNSDVIIYVGCGER NEMSEVL+DFP+LT+E+DG+ ESIMKRTA
Sbjct: 251 AFGCGKTVISQSLSKYSNSDVIIYVGCGERVNEMSEVLRDFPELTMEVDGKVESIMKRTA 310
Query: 181 LVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPA 360
LVANTSNMPVAAREASIYTGITLSEYFRDMGY+VSMMA+STSRWAEALREISGRLAEMPA
Sbjct: 311 LVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMANSTSRWAEALREISGRLAEMPA 370
Query: 361 ESGYPAYLGARLASFYERAGRVQCIGGPDERQGSVTIVGAVSPPGGDFSDPVTSATLGIV 540
+SGYPAYLGARLASFYERAGRV+C+G P ER+GSVTIVGAVSPPGGDFSDPVTSATLGIV
Sbjct: 371 DSGYPAYLGARLASFYERAGRVKCLGNP-EREGSVTIVGAVSPPGGDFSDPVTSATLGIV 429
Query: 541 QVFWGLDKKLAQRKHFPSI 597
QVFWGLDKKLAQRKHFPS+
Sbjct: 430 QVFWGLDKKLAQRKHFPSV 448
>sp|Q38677|VATA2_ACEAT Vacuolar ATP synthase catalytic subunit A isoform 2 (V-ATPase A
subunit 2) (Vacuolar proton pump alpha subunit 2)
(V-ATPase 69 kDa subunit 2)
Length = 613
Score = 357 bits (915), Expect = 2e-98
Identities = 179/200 (89%), Positives = 190/200 (95%), Gaps = 1/200 (0%)
Frame = +1
Query: 1 AFGCGKTVISQSLSKFSNSDVIIYVGCGERGNEMSEVLQDFPQLTVEI-DGRNESIMKRT 177
AFGCGKTVISQ+LSK+SNSD I+YVGCGERGNEM+EVL DFPQLT+ + DGR ESIMKRT
Sbjct: 241 AFGCGKTVISQALSKYSNSDGIVYVGCGERGNEMAEVLMDFPQLTMTMPDGREESIMKRT 300
Query: 178 ALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMP 357
LVANTSNMPVAAREASIYTGITLSEYFRDMGYN +MMADSTSRWAEALREISGRLAEMP
Sbjct: 301 TLVANTSNMPVAAREASIYTGITLSEYFRDMGYNFAMMADSTSRWAEALREISGRLAEMP 360
Query: 358 AESGYPAYLGARLASFYERAGRVQCIGGPDERQGSVTIVGAVSPPGGDFSDPVTSATLGI 537
A+SGYPAYLGARLASFYER+GRV CIG P ER+GSVTIVGAVSPPGGDFSDPVTSATLGI
Sbjct: 361 ADSGYPAYLGARLASFYERSGRVACIGSP-EREGSVTIVGAVSPPGGDFSDPVTSATLGI 419
Query: 538 VQVFWGLDKKLAQRKHFPSI 597
VQVFWGLDKKLAQRKHFPS+
Sbjct: 420 VQVFWGLDKKLAQRKHFPSV 439
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.317 0.133 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,675,450
Number of Sequences: 369166
Number of extensions: 1730709
Number of successful extensions: 6446
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5693
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5974
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4553075865
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)