Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_L10
(549 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P38607|VATA2_HUMAN Vacuolar ATP synthase catalytic subun... 245 5e-65
sp|Q27331|VATA2_DROME Vacuolar ATP synthase catalytic subun... 245 6e-65
sp|P31400|VATA_MANSE Vacuolar ATP synthase catalytic subuni... 236 2e-62
sp|P38606|VATA1_HUMAN Vacuolar ATP synthase catalytic subun... 232 4e-61
sp|P48602|VATA1_DROME Vacuolar ATP synthase catalytic subun... 232 4e-61
sp|Q29048|VATA1_PIG Vacuolar ATP synthase catalytic subunit... 227 1e-59
sp|P31404|VATA1_BOVIN Vacuolar ATP synthase catalytic subun... 226 2e-59
sp|P50516|VATA1_MOUSE Vacuolar ATP synthase catalytic subun... 224 8e-59
sp|Q9UVJ8|VATA_ASHGO Vacuolar ATP synthase catalytic subuni... 220 2e-57
sp|P17255|VATA_YEAST Vacuolar ATP synthase catalytic subuni... 213 2e-55
>sp|P38607|VATA2_HUMAN Vacuolar ATP synthase catalytic subunit A, osteoclast isoform
(V-ATPase A subunit 2) (Vacuolar proton pump alpha
subunit 2) (V-ATPase 69 kDa subunit 2) (Isoform HO68)
Length = 615
Score = 245 bits (626), Expect = 5e-65
Identities = 121/182 (66%), Positives = 144/182 (79%)
Frame = +2
Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181
GY +LVGEIIRLEGD ATIQVYEDTSGVTVGDPV++TGKPLSVELGPGIM SIFDGIQRP
Sbjct: 45 GYYELVGEIIRLEGDMATIQVYEDTSGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRP 104
Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPVNVSSGMHVSGGDVFGIVQENTLVKHKI 361
LK I S SIYIP+GVNVPAL+R+ +WDF PV+V G H++GGD++G+V ENTLVKHK+
Sbjct: 105 LKDINELSNSIYIPKGVNVPALSRTAQWDFSPVSVKVGSHITGGDLYGLVHENTLVKHKL 164
Query: 362 MVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANYP 541
++ P+ KG V +IA GNYTVD+ VL TEF+ ++K TM +KLPANYP
Sbjct: 165 LLPPRAKGTVTYIAEPGNYTVDDVVLETEFDGERSKFTMLQVWPVRQPRPVTEKLPANYP 224
Query: 542 LL 547
LL
Sbjct: 225 LL 226
>sp|Q27331|VATA2_DROME Vacuolar ATP synthase catalytic subunit A isoform 2 (V-ATPase A
subunit 2) (Vacuolar proton pump alpha subunit 2)
(V-ATPase 69 kDa subunit 2)
Length = 614
Score = 245 bits (625), Expect = 6e-65
Identities = 119/182 (65%), Positives = 145/182 (79%)
Frame = +2
Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181
GY +LVGEIIRLEGD ATIQVYE+TSGVTVGDPV++TGKPLSVELGPGIM SIFDGIQRP
Sbjct: 44 GYYELVGEIIRLEGDMATIQVYEETSGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRP 103
Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPVNVSSGMHVSGGDVFGIVQENTLVKHKI 361
LK I ++SIYIP+GVNVP+L+R W+F P+NV G H++GGD++G+V ENTLVKHK+
Sbjct: 104 LKDINELTESIYIPKGVNVPSLSRVASWEFNPLNVKVGSHITGGDLYGLVHENTLVKHKM 163
Query: 362 MVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANYP 541
+V+P+ KG V++IAP GNY VD+ VL TEF+ TKHTM +KLPAN+P
Sbjct: 164 IVNPRAKGTVRYIAPSGNYKVDDVVLETEFDGEITKHTMLQVWPVRHHAPVTEKLPANHP 223
Query: 542 LL 547
LL
Sbjct: 224 LL 225
>sp|P31400|VATA_MANSE Vacuolar ATP synthase catalytic subunit A (V-ATPase A subunit)
(Vacuolar proton pump alpha subunit) (V-ATPase 69 kDa
subunit)
Length = 617
Score = 236 bits (603), Expect = 2e-62
Identities = 114/182 (62%), Positives = 142/182 (78%)
Frame = +2
Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181
GY +LVGEIIRLEGD ATIQVYE+TSGVTVGDPV++TGKPLSVELGPGI+ SIFDGIQRP
Sbjct: 47 GYNELVGEIIRLEGDMATIQVYEETSGVTVGDPVLRTGKPLSVELGPGILGSIFDGIQRP 106
Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPVNVSSGMHVSGGDVFGIVQENTLVKHKI 361
LK I ++SIYIP+GVNVP+L R + W+F P+NV G H++GGD++GIV ENTLVKHK+
Sbjct: 107 LKDINELTQSIYIPKGVNVPSLAREVDWEFNPLNVKVGSHITGGDLYGIVHENTLVKHKM 166
Query: 362 MVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANYP 541
++ P+ KG V +IAP GNY V + VL TEF+ + ++TM +KLPAN+P
Sbjct: 167 LMPPRAKGTVTYIAPAGNYKVTDVVLETEFDGEKAQYTMLQVWPVRQPRPVTEKLPANHP 226
Query: 542 LL 547
LL
Sbjct: 227 LL 228
>sp|P38606|VATA1_HUMAN Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform
(V-ATPase A subunit 1) (Vacuolar proton pump alpha
subunit 1) (V-ATPase 69 kDa subunit 1) (Isoform VA68)
Length = 617
Score = 232 bits (592), Expect = 4e-61
Identities = 115/183 (62%), Positives = 141/183 (77%), Gaps = 1/183 (0%)
Frame = +2
Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181
G+ +LVGEIIRLEGD ATIQVYE+TSGV+VGDPV++TGKPLSVELGPGIM +IFDGIQRP
Sbjct: 46 GHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRP 105
Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPV-NVSSGMHVSGGDVFGIVQENTLVKHK 358
L I+SQ++SIYIPRGVNV AL+R IKWDF P N+ G H++GGD++GIV EN+L+KHK
Sbjct: 106 LSDISSQTQSIYIPRGVNVSALSRDIKWDFTPCKNLRVGSHITGGDIYGIVSENSLIKHK 165
Query: 359 IMVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANY 538
IM+ P+ +G V +IAP GNY + VL EF V+ K TM +KLPAN+
Sbjct: 166 IMLPPRNRGTVTYIAPPGNYDTSDVVLELEFEGVKEKFTMVQVWPVRQVRPVTEKLPANH 225
Query: 539 PLL 547
PLL
Sbjct: 226 PLL 228
>sp|P48602|VATA1_DROME Vacuolar ATP synthase catalytic subunit A isoform 1 (V-ATPase A
subunit 1) (Vacuolar proton pump alpha subunit 1)
(V-ATPase 69 kDa subunit 1)
Length = 614
Score = 232 bits (592), Expect = 4e-61
Identities = 113/181 (62%), Positives = 140/181 (77%)
Frame = +2
Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181
GY +LVGEIIRLEGD ATIQVYE+TSGVTVGDPV++TGKPLSVELGPGIM SIFDGIQRP
Sbjct: 44 GYYELVGEIIRLEGDMATIQVYEETSGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRP 103
Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPVNVSSGMHVSGGDVFGIVQENTLVKHKI 361
L+ I + SIYIP+GVN AL+RS W+F P+NV G H++GGD++G+V ENTLVK ++
Sbjct: 104 LRDIGVMTNSIYIPKGVNTTALSRSEMWEFNPLNVRVGSHITGGDLYGVVHENTLVKQRM 163
Query: 362 MVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANYP 541
+V P+ KG V++IAP GNY +++ VL TEF+ TKHTM +KLPAN+P
Sbjct: 164 IVAPRAKGTVRYIAPAGNYNLEDIVLETEFDGEITKHTMLQVWPVRQPRPVTEKLPANHP 223
Query: 542 L 544
L
Sbjct: 224 L 224
>sp|Q29048|VATA1_PIG Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform
(V-ATPase A subunit 1) (Vacuolar proton pump alpha
subunit 1) (V-ATPase 69 kDa subunit 1)
Length = 617
Score = 227 bits (579), Expect = 1e-59
Identities = 111/183 (60%), Positives = 141/183 (77%), Gaps = 1/183 (0%)
Frame = +2
Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181
G+ +LVGEIIRLEGD ATIQVYE+TSGV+VGDPV++TGKPLSVELGPGIM +IFDGIQRP
Sbjct: 46 GHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRP 105
Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQP-VNVSSGMHVSGGDVFGIVQENTLVKHK 358
L I+SQ++SIYIPRGVNV AL+R +KW+F P N+ G H++GGD++GIV EN+L+KH+
Sbjct: 106 LSDISSQTQSIYIPRGVNVSALSRDVKWEFTPSKNLRVGSHITGGDIYGIVNENSLIKHR 165
Query: 359 IMVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANY 538
IM+ P+ +G V +IAP GNY + VL EF V+ K +M +KLPAN+
Sbjct: 166 IMLPPRNRGTVTYIAPPGNYDTSDVVLELEFEGVKEKFSMVQVWPVRQVRPVTEKLPANH 225
Query: 539 PLL 547
PLL
Sbjct: 226 PLL 228
>sp|P31404|VATA1_BOVIN Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform
(V-ATPase A subunit 1) (Vacuolar proton pump alpha
subunit 1) (V-ATPase 69 kDa subunit 1)
Length = 617
Score = 226 bits (577), Expect = 2e-59
Identities = 111/183 (60%), Positives = 140/183 (76%), Gaps = 1/183 (0%)
Frame = +2
Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181
G+ +LVGEIIRLEGD ATIQVYE+TSGV+VGDPV++TGKPLSVEL PGIM +IFDGIQRP
Sbjct: 46 GHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELCPGIMGAIFDGIQRP 105
Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPV-NVSSGMHVSGGDVFGIVQENTLVKHK 358
L I+SQ++SIYIPRGVNV AL+R +KWDF P N+ G H++GGD++GIV EN+L+KHK
Sbjct: 106 LSDISSQTQSIYIPRGVNVSALSRDVKWDFTPCKNLRVGSHITGGDIYGIVNENSLIKHK 165
Query: 359 IMVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANY 538
IM+ P+ +G V +IAP GNY + VL EF ++ K +M +KLPAN+
Sbjct: 166 IMLPPRNRGTVTYIAPPGNYDTSDVVLELEFEGIKEKFSMVQVWPVRQVRPVTEKLPANH 225
Query: 539 PLL 547
PLL
Sbjct: 226 PLL 228
>sp|P50516|VATA1_MOUSE Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform
(V-ATPase A subunit 1) (Vacuolar proton pump alpha
subunit 1) (V-ATPase 69 kDa subunit 1)
Length = 617
Score = 224 bits (572), Expect = 8e-59
Identities = 112/183 (61%), Positives = 139/183 (75%), Gaps = 1/183 (0%)
Frame = +2
Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181
G+ +LVGEIIRLEGD ATIQVYE+TSGV+VGDPV++TGKP SVELGPGIM +IFDGIQRP
Sbjct: 46 GHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPRSVELGPGIMGAIFDGIQRP 105
Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQP-VNVSSGMHVSGGDVFGIVQENTLVKHK 358
L I+SQ++SIYIPRGVNV AL+R IKW+F P N+ G H++GGD++GIV EN+L+KHK
Sbjct: 106 LSDISSQTQSIYIPRGVNVSALSRDIKWEFIPSKNLRVGSHITGGDIYGIVNENSLIKHK 165
Query: 359 IMVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANY 538
IM+ P+ +G V +IAP GNY VL EF V+ K +M +KLPAN+
Sbjct: 166 IMLPPRNRGSVTYIAPPGNYDASNVVLELEFEGVKEKFSMVQVWPVRQVRPVTEKLPANH 225
Query: 539 PLL 547
PLL
Sbjct: 226 PLL 228
>sp|Q9UVJ8|VATA_ASHGO Vacuolar ATP synthase catalytic subunit A (V-ATPase A subunit)
(Vacuolar proton pump alpha subunit) (V-ATPase 69 kDa
subunit)
Length = 617
Score = 220 bits (561), Expect = 2e-57
Identities = 106/183 (57%), Positives = 140/183 (76%), Gaps = 1/183 (0%)
Frame = +2
Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181
G+ LVGE+IRL+GD ATIQVYE+T+GVTVGDPV++TGKPLSVELGPG+M++I+DGIQRP
Sbjct: 53 GHHNLVGEVIRLDGDKATIQVYEETAGVTVGDPVLRTGKPLSVELGPGLMETIYDGIQRP 112
Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPVNVSSGMHVSGGDVFGIVQENTLVK-HK 358
LK I QS+SIYIPRGV+ PAL+R +KW F+P + G H+SGGD+FG + EN+L++ HK
Sbjct: 113 LKAIKEQSQSIYIPRGVDAPALSREVKWAFKPGKLGVGDHISGGDIFGSIFENSLLEDHK 172
Query: 359 IMVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANY 538
I++ P+ +G + WIAP G YTVDETVL EF+ + ++M +KL A+Y
Sbjct: 173 ILLPPRARGTITWIAPAGEYTVDETVLEVEFDGKKYSYSMFHTWPVRVPRPVTEKLSADY 232
Query: 539 PLL 547
PLL
Sbjct: 233 PLL 235
>sp|P17255|VATA_YEAST Vacuolar ATP synthase catalytic subunit A (V-ATPase A subunit)
[Contains: Endonuclease PI-SceI (VMA1-derived
endonuclease) (VDE) (Sce VMA intein)]
Length = 1071
Score = 213 bits (543), Expect = 2e-55
Identities = 100/183 (54%), Positives = 137/183 (74%), Gaps = 1/183 (0%)
Frame = +2
Query: 2 GYGKLVGEIIRLEGDFATIQVYEDTSGVTVGDPVIKTGKPLSVELGPGIMDSIFDGIQRP 181
G+ LVGE+IR++GD ATIQVYE+T+G+TVGDPV++TGKPLSVELGPG+M++I+DGIQRP
Sbjct: 53 GHDNLVGEVIRIDGDKATIQVYEETAGLTVGDPVLRTGKPLSVELGPGLMETIYDGIQRP 112
Query: 182 LKFIASQSKSIYIPRGVNVPALNRSIKWDFQPVNVSSGMHVSGGDVFGIVQENTLV-KHK 358
LK I +S+SIYIPRG++ PAL+R+IKW F P G H+SGGD++G V EN+L+ HK
Sbjct: 113 LKAIKEESQSIYIPRGIDTPALDRTIKWQFTPGKFQVGDHISGGDIYGSVFENSLISSHK 172
Query: 359 IMVHPKEKGIVKWIAPRGNYTVDETVLITEFNKVQTKHTMXXXXXXXXXXXXADKLPANY 538
I++ P+ +G + WIAP G YT+DE +L EF+ ++ T+ +KL A+Y
Sbjct: 173 ILLPPRSRGTITWIAPAGEYTLDEKILEVEFDGKKSDFTLYHTWPVRVPRPVTEKLSADY 232
Query: 539 PLL 547
PLL
Sbjct: 233 PLL 235
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,796,062
Number of Sequences: 369166
Number of extensions: 1344379
Number of successful extensions: 3090
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2944
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3020
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3833118120
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)