Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00121 (654 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9BW30|CG38_HUMAN Protein CGI-38 90 6e-18 sp|Q9CRB6|CG38_MOUSE Protein CGI-38 homolog 88 2e-17 sp|P59282|P25B_HUMAN Protein p25-beta 87 5e-17 sp|Q7TQD2|P25A_MOUSE Tubulin polymerization-promoting prote... 84 2e-16 sp|O94811|P25A_HUMAN Tubulin polymerization-promoting prote... 81 3e-15 sp|Q27957|P25A_BOVIN Tubulin polymerization-promoting prote... 79 8e-15 sp|P91127|YBYK_CAEEL Hypothetical protein C32E8.3 in chromo... 67 5e-11 sp|Q9VV43|Y4893_DROME Hypothetical protein CG4893 67 5e-11 sp|Q4L5U2|TRMD_STAHJ tRNA (Guanine-N(1)-)-methyltransferase... 33 0.85 sp|P16342|R1AB_CVMA5 Replicase polyprotein 1ab (pp1ab) (ORF... 32 1.9
>sp|Q9BW30|CG38_HUMAN Protein CGI-38 Length = 176 Score = 89.7 bits (221), Expect = 6e-18 Identities = 56/148 (37%), Positives = 76/148 (51%), Gaps = 1/148 (0%) Frame = +2 Query: 71 KTLKKICTDCKIYC-KGFDQNRCDIQFRKHIGNAKKDVDYNDFVRFVEGPMAEAYMSARN 247 K K+C DCK+ K DI F K G + + ++Y +F + +E + + Sbjct: 33 KNWAKLCKDCKVADGKSVTGTDVDIVFSKVKGKSARVINYEEFKKALEELATKRFKGKSK 92 Query: 248 LAYEDAVQELKTKICQGSPAGHGTTGVSADAATARLTDVKGYTGAHKERFDAETGKGKGI 427 DA+ +L + PA G T A RLTD YTG+HKERFD E+GKGKGI Sbjct: 93 EEAFDAICQL---VAGKEPANVGVTKAKTGGAVDRLTDTSRYTGSHKERFD-ESGKGKGI 148 Query: 428 DGREYLAGENAQQGYVGGYKGAGTYDKK 511 GR+ + ++ GYV YK AGTYD K Sbjct: 149 AGRQDILDDS---GYVSAYKNAGTYDAK 173
>sp|Q9CRB6|CG38_MOUSE Protein CGI-38 homolog Length = 176 Score = 87.8 bits (216), Expect = 2e-17 Identities = 56/148 (37%), Positives = 75/148 (50%), Gaps = 1/148 (0%) Frame = +2 Query: 71 KTLKKICTDCKIYC-KGFDQNRCDIQFRKHIGNAKKDVDYNDFVRFVEGPMAEAYMSARN 247 K K+C DCK+ K DI F K + + ++Y +F + +E + + Sbjct: 33 KNWAKLCKDCKVADGKAVTGTDVDIVFSKVKAKSARVINYEEFKKALEELATKRFKGKSK 92 Query: 248 LAYEDAVQELKTKICQGSPAGHGTTGVSADAATARLTDVKGYTGAHKERFDAETGKGKGI 427 DA+ +L I PA G T A RLTD YTG+HKERFD E+GKGKGI Sbjct: 93 EEAFDAICQL---IAGKEPANIGVTKAKTGGAVDRLTDTSKYTGSHKERFD-ESGKGKGI 148 Query: 428 DGREYLAGENAQQGYVGGYKGAGTYDKK 511 GR+ + ++ GYV YK AGTYD K Sbjct: 149 AGRQDILDDS---GYVSAYKNAGTYDAK 173
>sp|P59282|P25B_HUMAN Protein p25-beta Length = 170 Score = 86.7 bits (213), Expect = 5e-17 Identities = 63/166 (37%), Positives = 81/166 (48%), Gaps = 2/166 (1%) Frame = +2 Query: 20 FAAFCDAVKKGSTTCTDKTLKKICTDCKIYC-KGFDQNRCDIQFRKHIGNAKKDVDYNDF 196 FAAF ++ G T +K K+C DC I K DI F K + + + F Sbjct: 12 FAAFGESSSSG-TEMNNKNFSKLCKDCGIMDGKTVTSTDVDIVFSKVKAKNARTITFQQF 70 Query: 197 VRFVEGPMAEAYMSARNLAYEDAVQELKTKICQGS-PAGHGTTGVSADAATARLTDVKGY 373 V+ + + ++ D V E + +G PA G T + A RLTD Y Sbjct: 71 KEAVK-ELGQKRFKGKS---PDEVLENIYGLMEGKDPATTGATKATTVGAVDRLTDTSKY 126 Query: 374 TGAHKERFDAETGKGKGIDGREYLAGENAQQGYVGGYKGAGTYDKK 511 TG HKE FD E+GKGKGI GRE + GYV GYKG+GTYDKK Sbjct: 127 TGTHKELFD-ESGKGKGIAGREEMTDNT---GYVSGYKGSGTYDKK 168
>sp|Q7TQD2|P25A_MOUSE Tubulin polymerization-promoting protein (TPPP) Length = 218 Score = 84.3 bits (207), Expect = 2e-16 Identities = 61/175 (34%), Positives = 87/175 (49%), Gaps = 6/175 (3%) Frame = +2 Query: 5 DLRAAFAAFCDAVKKGSTTCTDKTL-----KKICTDCKIYC-KGFDQNRCDIQFRKHIGN 166 +L A AF G T T K + K+C DC + K DI F K G Sbjct: 46 ELSALEEAFRRFAVHGDTRATGKEMHGKNWSKLCKDCHVIDGKNVTVTDVDIVFSKIKGK 105 Query: 167 AKKDVDYNDFVRFVEGPMAEAYMSARNLAYEDAVQELKTKICQGSPAGHGTTGVSADAAT 346 + + + + F +E + + ++ + E+AV+E+ I +P G T + Sbjct: 106 SCRTITFEQFQEALEELAKKRF---KDKSSEEAVREVHRLIEGRAPVISGVTKAVSSPTV 162 Query: 347 ARLTDVKGYTGAHKERFDAETGKGKGIDGREYLAGENAQQGYVGGYKGAGTYDKK 511 +RLTD +TG+HKERFD ++GKGKG GR L E+ GYV GYK AGTYD+K Sbjct: 163 SRLTDTSKFTGSHKERFD-QSGKGKGKAGRVDLVDES---GYVPGYKHAGTYDQK 213
>sp|O94811|P25A_HUMAN Tubulin polymerization-promoting protein (TPPP) (25 kDa brain-specific protein) (p25-alpha) (p24) (p25) Length = 219 Score = 80.9 bits (198), Expect = 3e-15 Identities = 53/148 (35%), Positives = 78/148 (52%), Gaps = 1/148 (0%) Frame = +2 Query: 71 KTLKKICTDCKIYC-KGFDQNRCDIQFRKHIGNAKKDVDYNDFVRFVEGPMAEAYMSARN 247 K K+C DC++ + DI F K G + + + + F +E + + ++ Sbjct: 74 KNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRF---KD 130 Query: 248 LAYEDAVQELKTKICQGSPAGHGTTGVSADAATARLTDVKGYTGAHKERFDAETGKGKGI 427 + E+AV+E+ I +P G T + +RLTD +TG+HKERFD +GKGKG Sbjct: 131 KSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFD-PSGKGKGK 189 Query: 428 DGREYLAGENAQQGYVGGYKGAGTYDKK 511 GR L E+ GYV GYK AGTYD+K Sbjct: 190 AGRVDLVDES---GYVSGYKHAGTYDQK 214
>sp|Q27957|P25A_BOVIN Tubulin polymerization-promoting protein (TPPP) (25 kDa brain-specific protein) (p25-alpha) Length = 218 Score = 79.3 bits (194), Expect = 8e-15 Identities = 52/148 (35%), Positives = 78/148 (52%), Gaps = 1/148 (0%) Frame = +2 Query: 71 KTLKKICTDCKIYC-KGFDQNRCDIQFRKHIGNAKKDVDYNDFVRFVEGPMAEAYMSARN 247 K K+C DC++ + DI F K G + + + + F +E + + ++ Sbjct: 73 KNWSKLCRDCQVIDGRSVTVTDVDIVFSKIKGKSCRTITFEQFKEALEELAKKRF---KD 129 Query: 248 LAYEDAVQELKTKICQGSPAGHGTTGVSADAATARLTDVKGYTGAHKERFDAETGKGKGI 427 + E+AV+E+ I +P G T + +RLTD +TG+HKERFD +G+GKG Sbjct: 130 KSAEEAVREVHKLIEGKAPIISGVTKAISSPTVSRLTDTSKFTGSHKERFD-PSGRGKGR 188 Query: 428 DGREYLAGENAQQGYVGGYKGAGTYDKK 511 GR L E+ GYV GYK AGTYD+K Sbjct: 189 AGRVDLVDES---GYVPGYKHAGTYDQK 213
>sp|P91127|YBYK_CAEEL Hypothetical protein C32E8.3 in chromosome I Length = 180 Score = 66.6 bits (161), Expect = 5e-11 Identities = 57/170 (33%), Positives = 74/170 (43%), Gaps = 2/170 (1%) Frame = +2 Query: 5 DLRAAFAAFCDAVKKGSTTCTDKTLKKICTDCKIYC-KGFDQNRCDIQFRKHIGNAKKDV 181 D++ + AF +T T K K D + K I F K G KK Sbjct: 13 DVKKRWDAFTKFGAATATEMTGKNFDKWLKDAGVLDNKAITGTMTGIAFSKVTGPKKKAT 72 Query: 182 DYNDFVRFVEGPMAEAYMSARNLAYEDAVQELKTKICQ-GSPAGHGTTGVSADAATARLT 358 D + V +AE +D + + K+ + +P+ G +A +RLT Sbjct: 73 F--DETKKVLAFVAEDRARQSKKPIQDELDAITEKLAKLEAPSVGGAAKANAAGVYSRLT 130 Query: 359 DVKGYTGAHKERFDAETGKGKGIDGREYLAGENAQQGYVGGYKGAGTYDK 508 D YTGAHKERFDAE GKGKG GR A GYVG YK +YDK Sbjct: 131 DHTKYTGAHKERFDAE-GKGKGKSGR---ADTTENTGYVGAYKNKDSYDK 176
>sp|Q9VV43|Y4893_DROME Hypothetical protein CG4893 Length = 192 Score = 66.6 bits (161), Expect = 5e-11 Identities = 57/167 (34%), Positives = 79/167 (47%), Gaps = 4/167 (2%) Frame = +2 Query: 17 AFAAFCDAVKKG---STTCTDKTLKKICTDCKIYCKGFDQNRCDIQFRKHIGNAKKDVDY 187 AF+ F D+ G + + +DK +K+ K+ K I F+K DY Sbjct: 43 AFSKFGDSKSDGKLITLSQSDKWMKQ----AKVIDKKITTTDTGIHFKKFKAMKISLSDY 98 Query: 188 NDFVRFVEGPMAEAYMSARNLAYEDAVQELKTKICQ-GSPAGHGTTGVSADAATARLTDV 364 N F+ + A+ E + E+K K+ G+P + A AA RLTD Sbjct: 99 NKFLDDL----------AKTKKVE--LSEIKQKLASCGAPGVVSVSAGKAAAAVDRLTDT 146 Query: 365 KGYTGAHKERFDAETGKGKGIDGREYLAGENAQQGYVGGYKGAGTYD 505 YTG+HKERFDA +GKGKGI GR + + GYV GY+ TYD Sbjct: 147 SKYTGSHKERFDA-SGKGKGIAGRRNVVDGS---GYVSGYQHKDTYD 189
>sp|Q4L5U2|TRMD_STAHJ tRNA (Guanine-N(1)-)-methyltransferase (M1G-methyltransferase) (tRNA [GM37] methyltransferase) Length = 245 Score = 32.7 bits (73), Expect = 0.85 Identities = 21/48 (43%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Frame = -2 Query: 362 HLSNEQLPHQQKL-RLYHGRQDYLDRF*FSILVLRLHKPNFLHSYKLQ 222 H + EQ H+QKL R YH R D LDR+ L F+ SYK Q Sbjct: 199 HANIEQWRHEQKLIRTYHKRPDLLDRY-----PLTEDDEKFIESYKKQ 241
>sp|P16342|R1AB_CVMA5 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Includes: Replicase polyprotein 1a (pp1a) (ORF1a)] [Contains: p28; p65; p210 (Papain-like proteinases 1/2) (PL1-PRO/PL2-PRO); Peptide HD2 (p44); 3C-like proteinase (3CL-PRO) (3CLp) (M-PRO) (p27); Unknown protein 1; p10; p22; p12; Growth factor-like peptide (GFL) (p15); RNA-directed RNA polymerase (RdRp) (Pol) (p100); Helicase (Hel) (p67); Unknown protein 2; p35; Unknown protein 3] Length = 7176 Score = 31.6 bits (70), Expect = 1.9 Identities = 13/45 (28%), Positives = 25/45 (55%) Frame = -3 Query: 343 CRISRNSGCTMAGRTTLTDFSFQFLYCVFISQISCTHISFSHWSF 209 CR++ + C M+GR +LT S+Q C + ++ + + +SF Sbjct: 3392 CRVTSSDFCVMSGRMSLTVMSYQMQGCQLVLTVTLQNPNTPKYSF 3436
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 66,260,110 Number of Sequences: 369166 Number of extensions: 1275091 Number of successful extensions: 4245 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4090 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4229 length of database: 68,354,980 effective HSP length: 106 effective length of database: 48,773,070 effective search space used: 5413810770 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)