Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00080 (1203 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P18298|METK_RAT S-adenosylmethionine synthetase gamma fo... 560 e-159 sp|P31153|METK_HUMAN S-adenosylmethionine synthetase gamma ... 560 e-159 sp|P13444|METL_RAT S-adenosylmethionine synthetase alpha an... 547 e-155 sp|Q00266|METL_HUMAN S-adenosylmethionine synthetase alpha ... 545 e-155 sp|P40320|METK_DROME S-adenosylmethionine synthetase (Methi... 522 e-148 sp|P50305|METK_CAEEL Probable S-adenosylmethionine syntheta... 521 e-147 sp|P50306|METL_CAEEL Probable S-adenosylmethionine syntheta... 518 e-146 sp|Q27522|METN_CAEEL Probable S-adenosylmethionine syntheta... 510 e-144 sp|O17680|METM_CAEEL Probable S-adenosylmethionine syntheta... 505 e-143 sp|P10659|METK_YEAST S-adenosylmethionine synthetase 1 (Met... 503 e-142
>sp|P18298|METK_RAT S-adenosylmethionine synthetase gamma form (Methionine adenosyltransferase) (AdoMet synthetase) (MAT-II) Length = 395 Score = 560 bits (1444), Expect = e-159 Identities = 270/381 (70%), Positives = 314/381 (82%) Frame = +1 Query: 22 EETFLFTSESVGEGHPDKICDQVSDAVLDAHLKQDPRAKVACETFSKTGMILIGGEITSN 201 E TFLFTSESVGEGHPDKICDQ++DAVLDAHL+QDP AKVACET +KTGMIL+ GEITS Sbjct: 15 EGTFLFTSESVGEGHPDKICDQINDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSR 74 Query: 202 AVVDYQSVIRQTIKEIGFDSCEKGFDYKTCNLLIAIEQQNPEIAKSVHEERSDEDIGAGD 381 A +DYQ V+R+ IK IG+D KGFDYKTCN+L+A+EQQ+P+IA+ VH +R++EDIGAGD Sbjct: 75 AAIDYQKVVREAIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGD 134 Query: 382 QGLMFGYATDETEELMPLTVVLAHGLNMKLAECRRNGTLPYLRPDTKTQVTVLYKSVQGA 561 QGLMFGYATDETEE MPLT+VLAH LN KLAE RRNGTLP+LRPD+KTQVTV Y +GA Sbjct: 135 QGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGA 194 Query: 562 CVPIRVHTVVISTQHDENVSIDQLREDLMCHVVKTVIPEIYLDANTIYHLNPSGRFVIGG 741 +PIRVHT+VIS QHDE V +D++R+ L ++K V+P YLD +TIYHL PSGRFVIGG Sbjct: 195 VIPIRVHTIVISVQHDEEVCLDEMRDALKEKLIKAVVPAKYLDEDTIYHLQPSGRFVIGG 254 Query: 742 PQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAGLCKRI 921 PQGDAGLTGRKIIVDTY KDYTKVDRS AYAARWVAKSLVK GLC+R+ Sbjct: 255 PQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRV 314 Query: 922 LVQLSYAIGIAAPLSIFVDSYGTSSMPDSKLLEIINNNFDLRPGHIEKDLDLRKPIYRRT 1101 LVQ+SYAIG++ PLSI + YGTS + +LLEI+ NNFDLRPG I +DLDL+KPIY+RT Sbjct: 315 LVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKNNFDLRPGVIVRDLDLKKPIYQRT 374 Query: 1102 ACYGHFGRSEFTWEQPKLLKY 1164 A YGHFGR F WE PK LKY Sbjct: 375 AAYGHFGRDSFPWEVPKKLKY 395
>sp|P31153|METK_HUMAN S-adenosylmethionine synthetase gamma form (Methionine adenosyltransferase) (AdoMet synthetase) (MAT-II) Length = 395 Score = 560 bits (1442), Expect = e-159 Identities = 271/381 (71%), Positives = 313/381 (82%) Frame = +1 Query: 22 EETFLFTSESVGEGHPDKICDQVSDAVLDAHLKQDPRAKVACETFSKTGMILIGGEITSN 201 E TFLFTSESVGEGHPDKICDQ+SDAVLDAHL+QDP AKVACET +KTGMIL+ GEITS Sbjct: 15 EGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSR 74 Query: 202 AVVDYQSVIRQTIKEIGFDSCEKGFDYKTCNLLIAIEQQNPEIAKSVHEERSDEDIGAGD 381 A VDYQ V+R+ +K IG+D KGFDYKTCN+L+A+EQQ+P+IA+ VH +R++EDIGAGD Sbjct: 75 AAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGD 134 Query: 382 QGLMFGYATDETEELMPLTVVLAHGLNMKLAECRRNGTLPYLRPDTKTQVTVLYKSVQGA 561 QGLMFGYATDETEE MPLT+VLAH LN KLAE RRNGTLP+LRPD+KTQVTV Y +GA Sbjct: 135 QGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGA 194 Query: 562 CVPIRVHTVVISTQHDENVSIDQLREDLMCHVVKTVIPEIYLDANTIYHLNPSGRFVIGG 741 +PIRVHT+VIS QHDE V +D++R+ L V+K V+P YLD +TIYHL PSGRFVIGG Sbjct: 195 VLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGG 254 Query: 742 PQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAGLCKRI 921 PQGDAGLTGRKIIVDTY KDYTKVDRS AYAARWVAKSLVK GLC+R+ Sbjct: 255 PQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRV 314 Query: 922 LVQLSYAIGIAAPLSIFVDSYGTSSMPDSKLLEIINNNFDLRPGHIEKDLDLRKPIYRRT 1101 LVQ+SYAIG++ PLSI + YGTS + +LLEI+ NFDLRPG I +DLDL+KPIY+RT Sbjct: 315 LVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRT 374 Query: 1102 ACYGHFGRSEFTWEQPKLLKY 1164 A YGHFGR F WE PK LKY Sbjct: 375 AAYGHFGRDSFPWEVPKKLKY 395
>sp|P13444|METL_RAT S-adenosylmethionine synthetase alpha and beta forms (Methionine adenosyltransferase) (AdoMet synthetase) (MAT-I/III) Length = 397 Score = 547 bits (1409), Expect = e-155 Identities = 261/382 (68%), Positives = 316/382 (82%), Gaps = 1/382 (0%) Frame = +1 Query: 22 EETFLFTSESVGEGHPDKICDQVSDAVLDAHLKQDPRAKVACETFSKTGMILIGGEITSN 201 E F+FTSESVGEGHPDKICDQ+SDAVLDAHLKQDP AKVACET KTGM+L+ GEITS Sbjct: 16 EGAFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSM 75 Query: 202 AVVDYQSVIRQTIKEIGFDSCEKGFDYKTCNLLIAIEQQNPEIAKSVHEERSDEDIGAGD 381 A++DYQ V+R TIK IG+D KGFD+KTCN+L+A+EQQ+P+IA+ VH +R++ED+GAGD Sbjct: 76 AMIDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGD 135 Query: 382 QGLMFGYATDETEELMPLTVVLAHGLNMKLAECRRNGTLPYLRPDTKTQVTVLYKSVQGA 561 QGLMFGYATDETEE MPLT+VLAH LN ++A+ RR+G LP+LRPD+KTQVTV Y GA Sbjct: 136 QGLMFGYATDETEECMPLTIVLAHKLNTRMADLRRSGVLPWLRPDSKTQVTVQYVQDNGA 195 Query: 562 CVPIRVHTVVISTQHDENVSIDQLREDLMCHVVKTVIPEIYLDANTIYHLNPSGRFVIGG 741 +P+RVHT+VIS QH+E+++++ +RE L V+K V+P YLD +TIYHL PSGRFVIGG Sbjct: 196 VIPVRVHTIVISVQHNEDITLEAMREALKEQVIKAVVPAKYLDEDTIYHLQPSGRFVIGG 255 Query: 742 PQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAGLCKRI 921 PQGDAG+TGRKIIVDTY KDYTKVDRS AYAARWVAKSLVKAGLC+R+ Sbjct: 256 PQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRV 315 Query: 922 LVQLSYAIGIAAPLSIFVDSYGTSSMPD-SKLLEIINNNFDLRPGHIEKDLDLRKPIYRR 1098 LVQ+SYAIG+A PLSI + +YGTS + +LLE++N NFDLRPG I +DLDL+KPIY++ Sbjct: 316 LVQVSYAIGVAEPLSISIFTYGTSKKTERDELLEVVNKNFDLRPGVIVRDLDLKKPIYQK 375 Query: 1099 TACYGHFGRSEFTWEQPKLLKY 1164 TACYGHFGRSEF WE PK L + Sbjct: 376 TACYGHFGRSEFPWEVPKKLVF 397
>sp|Q00266|METL_HUMAN S-adenosylmethionine synthetase alpha and beta forms (Methionine adenosyltransferase) (AdoMet synthetase) (MAT-I/III) Length = 395 Score = 545 bits (1405), Expect = e-155 Identities = 254/385 (65%), Positives = 318/385 (82%) Frame = +1 Query: 10 YNFGEETFLFTSESVGEGHPDKICDQVSDAVLDAHLKQDPRAKVACETFSKTGMILIGGE 189 ++ E F+FTSESVGEGHPDKICDQ+SDAVLDAHLKQDP AKVACET KTGM+L+ GE Sbjct: 11 HSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGE 70 Query: 190 ITSNAVVDYQSVIRQTIKEIGFDSCEKGFDYKTCNLLIAIEQQNPEIAKSVHEERSDEDI 369 ITS A+VDYQ V+R TIK IG+D KGFD+KTCN+L+A+EQQ+P+IA+ VH +R++ED+ Sbjct: 71 ITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDV 130 Query: 370 GAGDQGLMFGYATDETEELMPLTVVLAHGLNMKLAECRRNGTLPYLRPDTKTQVTVLYKS 549 GAGDQGLMFGYATDETEE MPLT++LAH LN ++A+ RR+G LP+LRPD+KTQVTV Y Sbjct: 131 GAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQ 190 Query: 550 VQGACVPIRVHTVVISTQHDENVSIDQLREDLMCHVVKTVIPEIYLDANTIYHLNPSGRF 729 GA +P+R+HT+VIS QH+E+++++++R L V++ V+P YLD +T+YHL PSGRF Sbjct: 191 DNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDTVYHLQPSGRF 250 Query: 730 VIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAGL 909 VIGGPQGDAG+TGRKIIVDTY KDYTKVDRS AYAARWVAKSLVKAGL Sbjct: 251 VIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGL 310 Query: 910 CKRILVQLSYAIGIAAPLSIFVDSYGTSSMPDSKLLEIINNNFDLRPGHIEKDLDLRKPI 1089 C+R+LVQ+SYAIG+A PLSI + +YGTS + +LL++++ NFDLRPG I +DLDL+KPI Sbjct: 311 CRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPI 370 Query: 1090 YRRTACYGHFGRSEFTWEQPKLLKY 1164 Y++TACYGHFGRSEF WE P+ L + Sbjct: 371 YQKTACYGHFGRSEFPWEVPRKLVF 395
>sp|P40320|METK_DROME S-adenosylmethionine synthetase (Methionine adenosyltransferase) (AdoMet synthetase) Length = 408 Score = 522 bits (1344), Expect = e-148 Identities = 256/378 (67%), Positives = 303/378 (80%) Frame = +1 Query: 28 TFLFTSESVGEGHPDKICDQVSDAVLDAHLKQDPRAKVACETFSKTGMILIGGEITSNAV 207 TFLFTSESVGEGHPDK+CDQ+SDA+LDAHLKQDP AKVACET +KTGMIL+ GEITS AV Sbjct: 28 TFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETVAKTGMILLCGEITSKAV 87 Query: 208 VDYQSVIRQTIKEIGFDSCEKGFDYKTCNLLIAIEQQNPEIAKSVHEERSDEDIGAGDQG 387 VDYQ V+R+T++ IG+D KGFD+KTCN+L+A++QQ+PEIA VH R++E+IGAGDQG Sbjct: 88 VDYQKVVRETVQHIGYDDSSKGFDFKTCNVLLALDQQSPEIAAGVHVNRAEEEIGAGDQG 147 Query: 388 LMFGYATDETEELMPLTVVLAHGLNMKLAECRRNGTLPYLRPDTKTQVTVLYKSVQGACV 567 +MFGYATDETEE MPLTVVLAH LN K+AE RR+ + RPD+KTQVT Y QG+ V Sbjct: 148 IMFGYATDETEECMPLTVVLAHKLNEKIAELRRSDVFWWARPDSKTQVTCEYLFNQGSAV 207 Query: 568 PIRVHTVVISTQHDENVSIDQLREDLMCHVVKTVIPEIYLDANTIYHLNPSGRFVIGGPQ 747 P RVHT+V+S QH E +S++ LR ++M VVK VIP Y+DANTI H+NP G FVIGGP Sbjct: 208 PKRVHTIVVSMQHSEKISLETLRSEVMEKVVKVVIPAKYIDANTIVHINPCGLFVIGGPM 267 Query: 748 GDAGLTGRKIIVDTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAGLCKRILV 927 GDAGLTGRKIIVDTY KD+TKVDRS AYAARWVAKSLVKAGLCKR LV Sbjct: 268 GDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKAGLCKRCLV 327 Query: 928 QLSYAIGIAAPLSIFVDSYGTSSMPDSKLLEIINNNFDLRPGHIEKDLDLRKPIYRRTAC 1107 Q+SYAIG+A PLSI V YGTS +LL+II NFDLRPG I KDL+LR+PIY+RT+ Sbjct: 328 QVSYAIGLAEPLSITVFDYGTSHKSQKELLDIIRRNFDLRPGKIVKDLNLRQPIYQRTST 387 Query: 1108 YGHFGRSEFTWEQPKLLK 1161 YGHFGR+ F+WE+ K L+ Sbjct: 388 YGHFGRAGFSWEEAKPLE 405
>sp|P50305|METK_CAEEL Probable S-adenosylmethionine synthetase C06E7.1 (Methionine adenosyltransferase) (AdoMet synthetase) Length = 404 Score = 521 bits (1343), Expect = e-147 Identities = 252/380 (66%), Positives = 306/380 (80%) Frame = +1 Query: 22 EETFLFTSESVGEGHPDKICDQVSDAVLDAHLKQDPRAKVACETFSKTGMILIGGEITSN 201 + FLFTSESV EGHPDK+CDQ+SDAVLDAHL QDP AKVACET +KTGMI++ GEITS Sbjct: 3 QHKFLFTSESVSEGHPDKMCDQISDAVLDAHLAQDPHAKVACETVTKTGMIMLCGEITSK 62 Query: 202 AVVDYQSVIRQTIKEIGFDSCEKGFDYKTCNLLIAIEQQNPEIAKSVHEERSDEDIGAGD 381 AVVDYQ ++R IK+IG+D KGFDYKTCN+L+A+EQQ+PEIA VH ++ +D+GAGD Sbjct: 63 AVVDYQVLVRNVIKKIGYDDSSKGFDYKTCNVLVALEQQSPEIAAGVHVDKDSDDVGAGD 122 Query: 382 QGLMFGYATDETEELMPLTVVLAHGLNMKLAECRRNGTLPYLRPDTKTQVTVLYKSVQGA 561 QG+MFGYATDETEE MPLT++L+H LN KL E RR+G L ++RPD+KTQVT+ Y S GA Sbjct: 123 QGIMFGYATDETEEAMPLTLLLSHKLNRKLHELRRSGELEWVRPDSKTQVTIEYASEGGA 182 Query: 562 CVPIRVHTVVISTQHDENVSIDQLREDLMCHVVKTVIPEIYLDANTIYHLNPSGRFVIGG 741 CVP+RVHTVVISTQH ++S+D LR++L+ V+K VIP +D TIYHLNP G F+IGG Sbjct: 183 CVPLRVHTVVISTQHSPDISLDDLRKELIEKVIKAVIPANLIDDKTIYHLNPCGSFIIGG 242 Query: 742 PQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAGLCKRI 921 P GDAGLTGRKIIVDTY KD TKVDRS AYAARWVAKSLVK+GLC+R Sbjct: 243 PMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKSGLCRRC 302 Query: 922 LVQLSYAIGIAAPLSIFVDSYGTSSMPDSKLLEIINNNFDLRPGHIEKDLDLRKPIYRRT 1101 LVQ+SYAIG+A PLS+ V S+GTS++ + +LL+I+N+NFDLRPG I KDLDL+KPIY T Sbjct: 303 LVQVSYAIGVAKPLSVMVFSFGTSALNEGELLKIVNDNFDLRPGMIIKDLDLKKPIYEPT 362 Query: 1102 ACYGHFGRSEFTWEQPKLLK 1161 A GHFG +EF WEQP+ L+ Sbjct: 363 AENGHFGHNEFPWEQPRHLQ 382
>sp|P50306|METL_CAEEL Probable S-adenosylmethionine synthetase C06E7.3 (Methionine adenosyltransferase) (AdoMet synthetase) Length = 404 Score = 518 bits (1335), Expect = e-146 Identities = 251/380 (66%), Positives = 303/380 (79%) Frame = +1 Query: 22 EETFLFTSESVGEGHPDKICDQVSDAVLDAHLKQDPRAKVACETFSKTGMILIGGEITSN 201 + FLFTSESV EGHPDK+CDQ+SDAVLDAHL QDP AKVACET +KTGMI++ GEITS Sbjct: 3 QHKFLFTSESVSEGHPDKMCDQISDAVLDAHLAQDPHAKVACETVTKTGMIMLCGEITSK 62 Query: 202 AVVDYQSVIRQTIKEIGFDSCEKGFDYKTCNLLIAIEQQNPEIAKSVHEERSDEDIGAGD 381 AVVDYQ ++R IK+IG+D KGFDYKTCN+L+A+EQQ+PEIA VH ++ +D+GAGD Sbjct: 63 AVVDYQVLVRNVIKKIGYDDSSKGFDYKTCNVLVALEQQSPEIAAGVHVDKDSDDVGAGD 122 Query: 382 QGLMFGYATDETEELMPLTVVLAHGLNMKLAECRRNGTLPYLRPDTKTQVTVLYKSVQGA 561 QG+MFGYATDETEE MPLT++L+H LN KL E RR+G L ++RPD+KTQVT+ Y S GA Sbjct: 123 QGIMFGYATDETEEAMPLTLLLSHKLNRKLHELRRSGELEWVRPDSKTQVTIEYASEGGA 182 Query: 562 CVPIRVHTVVISTQHDENVSIDQLREDLMCHVVKTVIPEIYLDANTIYHLNPSGRFVIGG 741 CVP+RVHTVVISTQH ++S+D LR++L+ V+K VIP +D TIYHLNP G F+IGG Sbjct: 183 CVPLRVHTVVISTQHSPDISLDDLRKELIEKVIKAVIPANLIDDKTIYHLNPCGSFIIGG 242 Query: 742 PQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAGLCKRI 921 P GDAGLTGRKIIVDTY KD TKVDRS AYAARWVAKSLVKAGLC+R Sbjct: 243 PMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKAGLCRRC 302 Query: 922 LVQLSYAIGIAAPLSIFVDSYGTSSMPDSKLLEIINNNFDLRPGHIEKDLDLRKPIYRRT 1101 LVQ+SYAIG+A PLS+ V S+GTS++ + LL I+N+NFDLRPG I K+LDL++PIY T Sbjct: 303 LVQVSYAIGVAKPLSVMVFSFGTSALSEEDLLTIVNDNFDLRPGKIIKNLDLKRPIYEPT 362 Query: 1102 ACYGHFGRSEFTWEQPKLLK 1161 A GHFG + F WEQP+ LK Sbjct: 363 AENGHFGHNNFPWEQPRNLK 382
>sp|Q27522|METN_CAEEL Probable S-adenosylmethionine synthetase T13A10.11 (Methionine adenosyltransferase) (AdoMet synthetase) Length = 404 Score = 510 bits (1314), Expect = e-144 Identities = 247/377 (65%), Positives = 304/377 (80%) Frame = +1 Query: 31 FLFTSESVGEGHPDKICDQVSDAVLDAHLKQDPRAKVACETFSKTGMILIGGEITSNAVV 210 FLFTSESV EGHPDK+CDQ+SDAVLDAHL QDP AKVACET +KTGMI++ GEITS AVV Sbjct: 6 FLFTSESVSEGHPDKMCDQISDAVLDAHLAQDPHAKVACETVTKTGMIMLCGEITSKAVV 65 Query: 211 DYQSVIRQTIKEIGFDSCEKGFDYKTCNLLIAIEQQNPEIAKSVHEERSDEDIGAGDQGL 390 DYQ ++R IK+IG+D KGFDYKTCN+L+A+EQQ+PEIA VH ++ D+GAGDQG+ Sbjct: 66 DYQVLVRNVIKKIGYDDSSKGFDYKTCNVLVALEQQSPEIAAGVHVDKDIADVGAGDQGI 125 Query: 391 MFGYATDETEELMPLTVVLAHGLNMKLAECRRNGTLPYLRPDTKTQVTVLYKSVQGACVP 570 MFGYATDETEE MPLT++L+H LN KL E RR+G L ++RPD+KTQVT+ Y S GACVP Sbjct: 126 MFGYATDETEEAMPLTLLLSHKLNYKLHELRRSGELEWVRPDSKTQVTIEYSSEGGACVP 185 Query: 571 IRVHTVVISTQHDENVSIDQLREDLMCHVVKTVIPEIYLDANTIYHLNPSGRFVIGGPQG 750 +RVHTVVISTQH ++S++ LR++L+ V+K VIP +D +T+YHLNP G FV+GGP G Sbjct: 186 LRVHTVVISTQHSPDISLEDLRKELIEKVIKVVIPGNLIDNDTVYHLNPCGSFVVGGPMG 245 Query: 751 DAGLTGRKIIVDTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAGLCKRILVQ 930 DAGLTGRKIIVDTY KD TKVDRS AYAARWVAKSLVKAGLC+R LVQ Sbjct: 246 DAGLTGRKIIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKAGLCRRCLVQ 305 Query: 931 LSYAIGIAAPLSIFVDSYGTSSMPDSKLLEIINNNFDLRPGHIEKDLDLRKPIYRRTACY 1110 +SYAIG+A PLS+ V S+GTS++ +++LL+I+N+NFDLRPG I K+LDL++ IY TA Sbjct: 306 VSYAIGVAKPLSVMVFSFGTSALNEAELLKIVNDNFDLRPGMIIKNLDLKRAIYEPTAEN 365 Query: 1111 GHFGRSEFTWEQPKLLK 1161 GHFG ++F WEQ + LK Sbjct: 366 GHFGHNDFPWEQARKLK 382
>sp|O17680|METM_CAEEL Probable S-adenosylmethionine synthetase C49F5.1 (Methionine adenosyltransferase) (AdoMet synthetase) Length = 403 Score = 505 bits (1301), Expect = e-143 Identities = 239/377 (63%), Positives = 303/377 (80%) Frame = +1 Query: 31 FLFTSESVGEGHPDKICDQVSDAVLDAHLKQDPRAKVACETFSKTGMILIGGEITSNAVV 210 FLFTSESV EGHPDK+CDQ+SDAVLDAHLKQDP AKVACET +KTGM+++ GEITS AVV Sbjct: 5 FLFTSESVSEGHPDKMCDQISDAVLDAHLKQDPNAKVACETVTKTGMVMLCGEITSKAVV 64 Query: 211 DYQSVIRQTIKEIGFDSCEKGFDYKTCNLLIAIEQQNPEIAKSVHEERSDEDIGAGDQGL 390 DYQ ++R+ I++IGF GFD+KTCN+L+A+EQQ+PEIA VH + ED+GAGDQG+ Sbjct: 65 DYQVLVRRVIEKIGFTDSSIGFDHKTCNVLVALEQQSPEIAAGVHVNKDGEDVGAGDQGI 124 Query: 391 MFGYATDETEELMPLTVVLAHGLNMKLAECRRNGTLPYLRPDTKTQVTVLYKSVQGACVP 570 MFGYATDETEE MPLT++L+H +N +L + RRNGTLP++RPD+K+QVT+ Y+S GA +P Sbjct: 125 MFGYATDETEETMPLTLILSHKINAELHKLRRNGTLPWVRPDSKSQVTIEYESRHGATIP 184 Query: 571 IRVHTVVISTQHDENVSIDQLREDLMCHVVKTVIPEIYLDANTIYHLNPSGRFVIGGPQG 750 +RVHTVV+STQH +V++++LRE ++ V+K VIP LD +T++H+NP G F++GGP G Sbjct: 185 LRVHTVVVSTQHSPDVTLEKLRETILADVIKKVIPASLLDESTVFHINPCGTFIVGGPMG 244 Query: 751 DAGLTGRKIIVDTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAGLCKRILVQ 930 DAG+TGRKIIVDTY KD TKVDRS AYAARWVA SLVKAGL KR+LVQ Sbjct: 245 DAGVTGRKIIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVATSLVKAGLAKRVLVQ 304 Query: 931 LSYAIGIAAPLSIFVDSYGTSSMPDSKLLEIINNNFDLRPGHIEKDLDLRKPIYRRTACY 1110 LSYAIGIA P+S+ V ++GTS + D +L +I+ ++FDL PG I K+LDL++PIY +TA Sbjct: 305 LSYAIGIAKPISVLVYAFGTSPLTDEELHQIVEDSFDLTPGKIIKELDLKRPIYEKTAEN 364 Query: 1111 GHFGRSEFTWEQPKLLK 1161 GHFG SEF WEQPK LK Sbjct: 365 GHFGHSEFPWEQPKALK 381
>sp|P10659|METK_YEAST S-adenosylmethionine synthetase 1 (Methionine adenosyltransferase 1) (AdoMet synthetase 1) Length = 382 Score = 503 bits (1294), Expect = e-142 Identities = 243/379 (64%), Positives = 297/379 (78%) Frame = +1 Query: 28 TFLFTSESVGEGHPDKICDQVSDAVLDAHLKQDPRAKVACETFSKTGMILIGGEITSNAV 207 TFLFTSESVGEGHPDKICDQVSDA+LDA L +DP +KVACET +KTGMI++ GEIT+ A Sbjct: 4 TFLFTSESVGEGHPDKICDQVSDAILDACLAEDPHSKVACETAAKTGMIMVFGEITTKAQ 63 Query: 208 VDYQSVIRQTIKEIGFDSCEKGFDYKTCNLLIAIEQQNPEIAKSVHEERSDEDIGAGDQG 387 +DYQ ++R TIK+IG+D KGFDYKTCN+L+AIEQQ+P+IA+ VHEE+ EDIGAGDQG Sbjct: 64 LDYQKIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQQSPDIAQGVHEEKDLEDIGAGDQG 123 Query: 388 LMFGYATDETEELMPLTVVLAHGLNMKLAECRRNGTLPYLRPDTKTQVTVLYKSVQGACV 567 +MFGYATDET E +PLT++LAH LNM +A+ RR+G+L +LRPDTKTQVTV YK G V Sbjct: 124 IMFGYATDETPEGLPLTILLAHKLNMAMADARRDGSLAWLRPDTKTQVTVEYKDDHGRWV 183 Query: 568 PIRVHTVVISTQHDENVSIDQLREDLMCHVVKTVIPEIYLDANTIYHLNPSGRFVIGGPQ 747 P R+ TVV+S QH + ++ + LR L +++ VIP LD NT Y + PSGRFVIGGPQ Sbjct: 184 PQRIDTVVVSAQHADEITTEDLRAQLKSEIIEKVIPRDMLDENTKYFIQPSGRFVIGGPQ 243 Query: 748 GDAGLTGRKIIVDTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAGLCKRILV 927 GDAGLTGRKIIVD Y KDY+KVDRS AYAARWVAKSLV AGLCKR+ V Sbjct: 244 GDAGLTGRKIIVDAYGGASSVGGGAFSGKDYSKVDRSAAYAARWVAKSLVAAGLCKRVQV 303 Query: 928 QLSYAIGIAAPLSIFVDSYGTSSMPDSKLLEIINNNFDLRPGHIEKDLDLRKPIYRRTAC 1107 Q SYAIGIA PLS+ VD+YGT++ D ++++II+ NFDLRPG + K+LDL +PIY TA Sbjct: 304 QFSYAIGIAEPLSLHVDTYGTATKSDEEIIDIISKNFDLRPGVLVKELDLARPIYLPTAS 363 Query: 1108 YGHFGRSEFTWEQPKLLKY 1164 YGHF E+ WE+PK LK+ Sbjct: 364 YGHFTNQEYPWEKPKTLKF 382
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 143,488,091 Number of Sequences: 369166 Number of extensions: 3058954 Number of successful extensions: 8119 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 7292 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7695 length of database: 68,354,980 effective HSP length: 113 effective length of database: 47,479,925 effective search space used: 13626738475 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)