Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_014_F23 (125 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P13444|METL_RAT S-adenosylmethionine synthetase alpha an... 54 1e-07 sp|Q00266|METL_HUMAN S-adenosylmethionine synthetase alpha ... 54 1e-07 sp|P18298|METK_RAT S-adenosylmethionine synthetase gamma fo... 52 4e-07 sp|P31153|METK_HUMAN S-adenosylmethionine synthetase gamma ... 52 4e-07 sp|P40320|METK_DROME S-adenosylmethionine synthetase (Methi... 52 4e-07 sp|P50306|METL_CAEEL Probable S-adenosylmethionine syntheta... 50 2e-06 sp|Q27522|METN_CAEEL Probable S-adenosylmethionine syntheta... 50 2e-06 sp|O60198|METK_SCHPO S-adenosylmethionine synthetase (Methi... 49 3e-06 sp|P50305|METK_CAEEL Probable S-adenosylmethionine syntheta... 49 5e-06 sp|P19358|METL_YEAST S-adenosylmethionine synthetase 2 (Met... 48 8e-06
>sp|P13444|METL_RAT S-adenosylmethionine synthetase alpha and beta forms (Methionine adenosyltransferase) (AdoMet synthetase) (MAT-I/III) Length = 397 Score = 53.5 bits (127), Expect = 1e-07 Identities = 27/41 (65%), Positives = 27/41 (65%) Frame = +3 Query: 3 DTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAG 125 DTY KDYTKVDRS AYAARWVAKSLVKAG Sbjct: 270 DTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAG 310
>sp|Q00266|METL_HUMAN S-adenosylmethionine synthetase alpha and beta forms (Methionine adenosyltransferase) (AdoMet synthetase) (MAT-I/III) Length = 395 Score = 53.5 bits (127), Expect = 1e-07 Identities = 27/41 (65%), Positives = 27/41 (65%) Frame = +3 Query: 3 DTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAG 125 DTY KDYTKVDRS AYAARWVAKSLVKAG Sbjct: 269 DTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAG 309
>sp|P18298|METK_RAT S-adenosylmethionine synthetase gamma form (Methionine adenosyltransferase) (AdoMet synthetase) (MAT-II) Length = 395 Score = 52.0 bits (123), Expect = 4e-07 Identities = 26/41 (63%), Positives = 26/41 (63%) Frame = +3 Query: 3 DTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAG 125 DTY KDYTKVDRS AYAARWVAKSLVK G Sbjct: 269 DTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGG 309
>sp|P31153|METK_HUMAN S-adenosylmethionine synthetase gamma form (Methionine adenosyltransferase) (AdoMet synthetase) (MAT-II) Length = 395 Score = 52.0 bits (123), Expect = 4e-07 Identities = 26/41 (63%), Positives = 26/41 (63%) Frame = +3 Query: 3 DTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAG 125 DTY KDYTKVDRS AYAARWVAKSLVK G Sbjct: 269 DTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGG 309
>sp|P40320|METK_DROME S-adenosylmethionine synthetase (Methionine adenosyltransferase) (AdoMet synthetase) Length = 408 Score = 52.0 bits (123), Expect = 4e-07 Identities = 26/41 (63%), Positives = 27/41 (65%) Frame = +3 Query: 3 DTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAG 125 DTY KD+TKVDRS AYAARWVAKSLVKAG Sbjct: 280 DTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKAG 320
>sp|P50306|METL_CAEEL Probable S-adenosylmethionine synthetase C06E7.3 (Methionine adenosyltransferase) (AdoMet synthetase) Length = 404 Score = 49.7 bits (117), Expect = 2e-06 Identities = 26/41 (63%), Positives = 26/41 (63%) Frame = +3 Query: 3 DTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAG 125 DTY KD TKVDRS AYAARWVAKSLVKAG Sbjct: 257 DTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKAG 297
>sp|Q27522|METN_CAEEL Probable S-adenosylmethionine synthetase T13A10.11 (Methionine adenosyltransferase) (AdoMet synthetase) Length = 404 Score = 49.7 bits (117), Expect = 2e-06 Identities = 26/41 (63%), Positives = 26/41 (63%) Frame = +3 Query: 3 DTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAG 125 DTY KD TKVDRS AYAARWVAKSLVKAG Sbjct: 257 DTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKAG 297
>sp|O60198|METK_SCHPO S-adenosylmethionine synthetase (Methionine adenosyltransferase) (AdoMet synthetase) Length = 382 Score = 49.3 bits (116), Expect = 3e-06 Identities = 24/41 (58%), Positives = 26/41 (63%) Frame = +3 Query: 3 DTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAG 125 DTY KDY+KVDRS AYAARW+AKSLV AG Sbjct: 256 DTYGGWGAHGGGAFSGKDYSKVDRSAAYAARWIAKSLVAAG 296
>sp|P50305|METK_CAEEL Probable S-adenosylmethionine synthetase C06E7.1 (Methionine adenosyltransferase) (AdoMet synthetase) Length = 404 Score = 48.5 bits (114), Expect = 5e-06 Identities = 25/41 (60%), Positives = 26/41 (63%) Frame = +3 Query: 3 DTYXXXXXXXXXXXXXKDYTKVDRSGAYAARWVAKSLVKAG 125 DTY KD TKVDRS AYAARWVAKSLVK+G Sbjct: 257 DTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKSG 297
>sp|P19358|METL_YEAST S-adenosylmethionine synthetase 2 (Methionine adenosyltransferase 2) (AdoMet synthetase 2) Length = 384 Score = 47.8 bits (112), Expect = 8e-06 Identities = 22/25 (88%), Positives = 23/25 (92%) Frame = +3 Query: 51 KDYTKVDRSGAYAARWVAKSLVKAG 125 KDY+KVDRS AYAARWVAKSLV AG Sbjct: 274 KDYSKVDRSAAYAARWVAKSLVAAG 298
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,928,219 Number of Sequences: 369166 Number of extensions: 205477 Number of successful extensions: 737 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 726 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 737 length of database: 68,354,980 effective HSP length: 15 effective length of database: 65,583,955 effective search space used: 1705182830 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)