Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_A09
(267 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P18298|METK_RAT S-adenosylmethionine synthetase gamma fo... 107 9e-24
sp|Q00266|METL_HUMAN S-adenosylmethionine synthetase alpha ... 106 1e-23
sp|P13444|METL_RAT S-adenosylmethionine synthetase alpha an... 105 3e-23
sp|P19358|METL_YEAST S-adenosylmethionine synthetase 2 (Met... 105 3e-23
sp|O60198|METK_SCHPO S-adenosylmethionine synthetase (Methi... 105 3e-23
sp|P31153|METK_HUMAN S-adenosylmethionine synthetase gamma ... 105 4e-23
sp|Q27522|METN_CAEEL Probable S-adenosylmethionine syntheta... 104 6e-23
sp|P10659|METK_YEAST S-adenosylmethionine synthetase 1 (Met... 104 6e-23
sp|P40320|METK_DROME S-adenosylmethionine synthetase (Methi... 103 1e-22
sp|P50306|METL_CAEEL Probable S-adenosylmethionine syntheta... 103 2e-22
>sp|P18298|METK_RAT S-adenosylmethionine synthetase gamma form (Methionine
adenosyltransferase) (AdoMet synthetase) (MAT-II)
Length = 395
Score = 107 bits (267), Expect = 9e-24
Identities = 53/88 (60%), Positives = 63/88 (71%)
Frame = +2
Query: 2 IIVDTYXXXXXXXXXXXXXKDYTKVERSGAYAARWVAKSLVKAGLCKRILVQLSYAIGIA 181
IIVDTY KDYTKV+RS AYAARWVAKSLVK GLC+R+LVQ+SYAIG++
Sbjct: 266 IIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVS 325
Query: 182 APLSIFVDRYGTRSMPDSKLLEIINNNF 265
PLSI + YGT + +LLEI+ NNF
Sbjct: 326 HPLSISIFHYGTSQKSERELLEIVKNNF 353
>sp|Q00266|METL_HUMAN S-adenosylmethionine synthetase alpha and beta forms (Methionine
adenosyltransferase) (AdoMet synthetase) (MAT-I/III)
Length = 395
Score = 106 bits (265), Expect = 1e-23
Identities = 52/88 (59%), Positives = 64/88 (72%)
Frame = +2
Query: 2 IIVDTYXXXXXXXXXXXXXKDYTKVERSGAYAARWVAKSLVKAGLCKRILVQLSYAIGIA 181
IIVDTY KDYTKV+RS AYAARWVAKSLVKAGLC+R+LVQ+SYAIG+A
Sbjct: 266 IIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVA 325
Query: 182 APLSIFVDRYGTRSMPDSKLLEIINNNF 265
PLSI + YGT + +LL++++ NF
Sbjct: 326 EPLSISIFTYGTSQKTERELLDVVHKNF 353
>sp|P13444|METL_RAT S-adenosylmethionine synthetase alpha and beta forms (Methionine
adenosyltransferase) (AdoMet synthetase) (MAT-I/III)
Length = 397
Score = 105 bits (262), Expect = 3e-23
Identities = 54/89 (60%), Positives = 64/89 (71%), Gaps = 1/89 (1%)
Frame = +2
Query: 2 IIVDTYXXXXXXXXXXXXXKDYTKVERSGAYAARWVAKSLVKAGLCKRILVQLSYAIGIA 181
IIVDTY KDYTKV+RS AYAARWVAKSLVKAGLC+R+LVQ+SYAIG+A
Sbjct: 267 IIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVA 326
Query: 182 APLSIFVDRYGTRSMPD-SKLLEIINNNF 265
PLSI + YGT + +LLE++N NF
Sbjct: 327 EPLSISIFTYGTSKKTERDELLEVVNKNF 355
>sp|P19358|METL_YEAST S-adenosylmethionine synthetase 2 (Methionine adenosyltransferase
2) (AdoMet synthetase 2)
Length = 384
Score = 105 bits (262), Expect = 3e-23
Identities = 53/88 (60%), Positives = 61/88 (69%)
Frame = +2
Query: 2 IIVDTYXXXXXXXXXXXXXKDYTKVERSGAYAARWVAKSLVKAGLCKRILVQLSYAIGIA 181
IIVD Y KDY+KV+RS AYAARWVAKSLV AGLCKR+ VQ SYAIGIA
Sbjct: 255 IIVDAYGGASSVGGGAFSGKDYSKVDRSAAYAARWVAKSLVAAGLCKRVQVQFSYAIGIA 314
Query: 182 APLSIFVDRYGTRSMPDSKLLEIINNNF 265
PLS+ VD YGT + D +++EII NF
Sbjct: 315 EPLSLHVDTYGTATKSDDEIIEIIKKNF 342
>sp|O60198|METK_SCHPO S-adenosylmethionine synthetase (Methionine adenosyltransferase)
(AdoMet synthetase)
Length = 382
Score = 105 bits (262), Expect = 3e-23
Identities = 54/88 (61%), Positives = 63/88 (71%)
Frame = +2
Query: 2 IIVDTYXXXXXXXXXXXXXKDYTKVERSGAYAARWVAKSLVKAGLCKRILVQLSYAIGIA 181
IIVDTY KDY+KV+RS AYAARW+AKSLV AGL +R LVQLSYAIG+A
Sbjct: 253 IIVDTYGGWGAHGGGAFSGKDYSKVDRSAAYAARWIAKSLVAAGLARRCLVQLSYAIGVA 312
Query: 182 APLSIFVDRYGTRSMPDSKLLEIINNNF 265
PLSIFV+ YGT S ++L+EII NF
Sbjct: 313 EPLSIFVNTYGTSSKTSAELVEIIRKNF 340
>sp|P31153|METK_HUMAN S-adenosylmethionine synthetase gamma form (Methionine
adenosyltransferase) (AdoMet synthetase) (MAT-II)
Length = 395
Score = 105 bits (261), Expect = 4e-23
Identities = 52/88 (59%), Positives = 62/88 (70%)
Frame = +2
Query: 2 IIVDTYXXXXXXXXXXXXXKDYTKVERSGAYAARWVAKSLVKAGLCKRILVQLSYAIGIA 181
IIVDTY KDYTKV+RS AYAARWVAKSLVK GLC+R+LVQ+SYAIG++
Sbjct: 266 IIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVS 325
Query: 182 APLSIFVDRYGTRSMPDSKLLEIINNNF 265
PLSI + YGT + +LLEI+ NF
Sbjct: 326 HPLSISIFHYGTSQKSERELLEIVKKNF 353
>sp|Q27522|METN_CAEEL Probable S-adenosylmethionine synthetase T13A10.11 (Methionine
adenosyltransferase) (AdoMet synthetase)
Length = 404
Score = 104 bits (260), Expect = 6e-23
Identities = 52/88 (59%), Positives = 66/88 (75%)
Frame = +2
Query: 2 IIVDTYXXXXXXXXXXXXXKDYTKVERSGAYAARWVAKSLVKAGLCKRILVQLSYAIGIA 181
IIVDTY KD TKV+RS AYAARWVAKSLVKAGLC+R LVQ+SYAIG+A
Sbjct: 254 IIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKAGLCRRCLVQVSYAIGVA 313
Query: 182 APLSIFVDRYGTRSMPDSKLLEIINNNF 265
PLS+ V +GT ++ +++LL+I+N+NF
Sbjct: 314 KPLSVMVFSFGTSALNEAELLKIVNDNF 341
>sp|P10659|METK_YEAST S-adenosylmethionine synthetase 1 (Methionine adenosyltransferase
1) (AdoMet synthetase 1)
Length = 382
Score = 104 bits (260), Expect = 6e-23
Identities = 52/88 (59%), Positives = 62/88 (70%)
Frame = +2
Query: 2 IIVDTYXXXXXXXXXXXXXKDYTKVERSGAYAARWVAKSLVKAGLCKRILVQLSYAIGIA 181
IIVD Y KDY+KV+RS AYAARWVAKSLV AGLCKR+ VQ SYAIGIA
Sbjct: 253 IIVDAYGGASSVGGGAFSGKDYSKVDRSAAYAARWVAKSLVAAGLCKRVQVQFSYAIGIA 312
Query: 182 APLSIFVDRYGTRSMPDSKLLEIINNNF 265
PLS+ VD YGT + D ++++II+ NF
Sbjct: 313 EPLSLHVDTYGTATKSDEEIIDIISKNF 340
>sp|P40320|METK_DROME S-adenosylmethionine synthetase (Methionine adenosyltransferase)
(AdoMet synthetase)
Length = 408
Score = 103 bits (258), Expect = 1e-22
Identities = 55/88 (62%), Positives = 61/88 (69%)
Frame = +2
Query: 2 IIVDTYXXXXXXXXXXXXXKDYTKVERSGAYAARWVAKSLVKAGLCKRILVQLSYAIGIA 181
IIVDTY KD+TKV+RS AYAARWVAKSLVKAGLCKR LVQ+SYAIG+A
Sbjct: 277 IIVDTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKAGLCKRCLVQVSYAIGLA 336
Query: 182 APLSIFVDRYGTRSMPDSKLLEIINNNF 265
PLSI V YGT +LL+II NF
Sbjct: 337 EPLSITVFDYGTSHKSQKELLDIIRRNF 364
>sp|P50306|METL_CAEEL Probable S-adenosylmethionine synthetase C06E7.3 (Methionine
adenosyltransferase) (AdoMet synthetase)
Length = 404
Score = 103 bits (256), Expect = 2e-22
Identities = 52/88 (59%), Positives = 63/88 (71%)
Frame = +2
Query: 2 IIVDTYXXXXXXXXXXXXXKDYTKVERSGAYAARWVAKSLVKAGLCKRILVQLSYAIGIA 181
IIVDTY KD TKV+RS AYAARWVAKSLVKAGLC+R LVQ+SYAIG+A
Sbjct: 254 IIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKAGLCRRCLVQVSYAIGVA 313
Query: 182 APLSIFVDRYGTRSMPDSKLLEIINNNF 265
PLS+ V +GT ++ + LL I+N+NF
Sbjct: 314 KPLSVMVFSFGTSALSEEDLLTIVNDNF 341
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,765,691
Number of Sequences: 369166
Number of extensions: 650389
Number of successful extensions: 1772
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1734
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1772
length of database: 68,354,980
effective HSP length: 58
effective length of database: 57,640,350
effective search space used: 1729210500
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)