Planarian EST Database

DrC_00007

Cluster detail
GO Category :
Consensus Sequence :
>DrC_00007 GTGTAATGAATTTCTATATTATCAGTCTTTTTATTCTAAATTTTCTTTACGTGACATCTG CAATTAGATTTTTTGTTACTCCAAACGGAGGAAAAAAATGTTTGAAAGAAGAAATTCATA AAAATGTTTTAGTTACAGGTGAATATGACATTACAGATGCTCCTGGACAGAAAGCTTCTA TTCAAGTTACAGATTCTAAGTCTCATGTTCTTTATCAAAAAGACGATATTGCTAAAGGTA AATTCGCGTTTACCACCGAAGAATATGAAATGTTTGATGTTTGCGTTGAAACTAAATTAA TGGGAGGTGGTAAAGGTCCCGATAGAGAAGTATTCTTGGATATAAAACATGGAGTGGAAA CTAAAAATTACGATAGTCTGGCACAAGCGGAAAAATTGAAACCTTTGGAAGTGGAATTGA AGCGATTAGAAGATCTCAGTGATGAAATTGTCAAAGATTTCCAATATATGCGAGACCGCG AAGAGAAAATGCGGGATACAAACGAATCAACTCACAATCGAGTCTTCTATTTCTCGCTCT TCTCGATGGCCTGCTTGATGGGACTCGCTATTTGGCAGGTTCTTTATTTGAGGAGATATT TCAAATCAAAGAAATTGATCGAGTAGAAATGTTATCGAAGCAGCAAATCTGATGTGTGCA CGAGTGTGTGTGTTTTGTTGTTGTGCGTATTTTTGATTGGATAAAATGAGAAACTAGTTC TATAATTAAATTGGAGTTGACTTCGTTTTGTATTTTGCAATAATAATAATAATAAAATCT ATTTTGTCATCATTTGTATACAAACTGTCGGGATTGGTGTCTGTGTGTGTCTGTGATCGA TCGTGCCCGTGTGATCGATGTGTGCATTGTAAATATTATTATTGTTCCAAGTAAATCACT G

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00007
         (901 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q28735|TMEDA_RABIT  Transmembrane emp24 domain containing...   248   1e-65
sp|Q63584|TMEDA_RAT  Transmembrane emp24 domain containing p...   248   2e-65
sp|Q5E971|TMEDA_BOVIN  Transmembrane emp24 domain containing...   248   2e-65
sp|O35587|TMEDA_MESAU  Transmembrane protein Tmp21 precursor...   248   2e-65
sp|Q9D1D4|TMEDA_MOUSE  Transmembrane emp24 domain containing...   247   3e-65
sp|P49755|TMEDA_HUMAN  Transmembrane emp24 domain containing...   247   4e-65
sp|Q5RE32|TMEDA_PONPY  Transmembrane emp24 domain containing...   246   6e-65
sp|Q90515|TMEDA_FUGRU  Transmembrane emp24 domain containing...   241   2e-63
sp|P54837|ERV25_YEAST  Protein ERV25 precursor                    134   5e-31
sp|Q9BVK6|TMED9_HUMAN  Transmembrane emp24 domain containing...    98   4e-20

>sp|Q28735|TMEDA_RABIT Transmembrane emp24 domain containing protein 10 precursor
           (Transmembrane protein Tmp21) (21 kDa transmembrane
           trafficking protein) (Integral membrane protein p23)
          Length = 219

 Score =  248 bits (634), Expect = 1e-65
 Identities = 124/206 (60%), Positives = 159/206 (77%), Gaps = 5/206 (2%)
 Frame = +3

Query: 21  ISLFILNFLYVTSAIRF-FVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQ 185
           ++L  L  L  +S +   F  P   +KCL+EEIHK++LVTG Y+ITD    A G +  ++
Sbjct: 16  LALLFLFLLGPSSVLAISFHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLK 75

Query: 186 VTDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETK 365
           +TDS  H+LY K+D +KGKFAFTTE+Y+MF+VC E+K  G G+ PD+ V LD+KHGVE K
Sbjct: 76  ITDSAGHILYSKEDASKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAK 133

Query: 366 NYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLFS 545
           NY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+FS
Sbjct: 134 NYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFS 193

Query: 546 MACLMGLAIWQVLYLRRYFKSKKLIE 623
           M CL+GLA WQV YLRR+FK+KKLIE
Sbjct: 194 MFCLIGLATWQVFYLRRFFKAKKLIE 219

>sp|Q63584|TMEDA_RAT Transmembrane emp24 domain containing protein 10 precursor
           (Transmembrane protein Tmp21) (21 kDa transmembrane
           trafficking protein)
          Length = 219

 Score =  248 bits (633), Expect = 2e-65
 Identities = 124/208 (59%), Positives = 159/208 (76%), Gaps = 6/208 (2%)
 Frame = +3

Query: 18  IISLFILNFLYVTSAIR--FFVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKAS 179
           ++S  +  FL   S++    F  P   +KCL+EEIHK++LVTG Y+ITD    A G +  
Sbjct: 14  LLSALLFLFLLGPSSVLGISFHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTH 73

Query: 180 IQVTDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVE 359
           +++TDS  H+LY K+D  KGKFAFTTE+Y+MF+VC E+K  G G+ PD+ V LD+KHGVE
Sbjct: 74  LKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVE 131

Query: 360 TKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSL 539
            KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+
Sbjct: 132 AKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSI 191

Query: 540 FSMACLMGLAIWQVLYLRRYFKSKKLIE 623
           FSM CL+GLA WQV YLRR+FK+KKLIE
Sbjct: 192 FSMFCLIGLATWQVFYLRRFFKAKKLIE 219

>sp|Q5E971|TMEDA_BOVIN Transmembrane emp24 domain containing protein 10 precursor
           (Transmembrane protein Tmp21) (21 kDa transmembrane
           trafficking protein)
          Length = 219

 Score =  248 bits (633), Expect = 2e-65
 Identities = 124/205 (60%), Positives = 158/205 (77%), Gaps = 5/205 (2%)
 Frame = +3

Query: 24  SLFILNFLYVTSAIRF-FVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQV 188
           +L +L  L  +S +   F  P   +KCL+EEIHK++LVTG Y+ITD    A G +  +++
Sbjct: 17  ALLLLLLLGPSSVLAISFHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKI 76

Query: 189 TDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKN 368
           TDS  H+LY K+D  KGKFAFTTE+Y+MF+VC E+K  G G+ PD+ V LD+KHGVE KN
Sbjct: 77  TDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKN 134

Query: 369 YDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLFSM 548
           Y+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+FSM
Sbjct: 135 YEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSM 194

Query: 549 ACLMGLAIWQVLYLRRYFKSKKLIE 623
            CL+GLA WQV YLRR+FK+KKLIE
Sbjct: 195 FCLIGLATWQVFYLRRFFKAKKLIE 219

>sp|O35587|TMEDA_MESAU Transmembrane protein Tmp21 precursor (21 kDa transmembrane
           trafficking protein) (Integral membrane protein p23)
          Length = 219

 Score =  248 bits (632), Expect = 2e-65
 Identities = 120/188 (63%), Positives = 150/188 (79%), Gaps = 4/188 (2%)
 Frame = +3

Query: 72  FVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDIAKG 239
           F  P   +KCL+EEIHK++LVTG Y+ITD    A G +  +++TDS  H+LY K+D  KG
Sbjct: 34  FHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYAKEDATKG 93

Query: 240 KFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVEL 419
           KFAFTTE+Y+MF+VC E+K  G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL
Sbjct: 94  KFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVEL 151

Query: 420 KRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRY 599
           +RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+
Sbjct: 152 RRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMLCLIGLATWQVFYLRRF 211

Query: 600 FKSKKLIE 623
           FK+KKLIE
Sbjct: 212 FKAKKLIE 219

>sp|Q9D1D4|TMEDA_MOUSE Transmembrane emp24 domain containing protein 10 precursor
           (Transmembrane protein Tmp21) (21 kDa transmembrane
           trafficking protein)
          Length = 219

 Score =  247 bits (631), Expect = 3e-65
 Identities = 120/188 (63%), Positives = 150/188 (79%), Gaps = 4/188 (2%)
 Frame = +3

Query: 72  FVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDIAKG 239
           F  P   +KCL+EEIHK++LVTG Y+ITD    A G +  +++TDS  H+LY K+D  KG
Sbjct: 34  FHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYAKEDATKG 93

Query: 240 KFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVEL 419
           KFAFTTE+Y+MF+VC E+K  G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL
Sbjct: 94  KFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVEL 151

Query: 420 KRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRY 599
           +RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+
Sbjct: 152 RRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRF 211

Query: 600 FKSKKLIE 623
           FK+KKLIE
Sbjct: 212 FKAKKLIE 219

>sp|P49755|TMEDA_HUMAN Transmembrane emp24 domain containing protein 10 precursor
           (Transmembrane protein Tmp21) (21 kDa transmembrane
           trafficking protein) (p24delta) (S31III125) (S31I125)
           (Tmp-21-I)
          Length = 219

 Score =  247 bits (630), Expect = 4e-65
 Identities = 125/206 (60%), Positives = 161/206 (78%), Gaps = 4/206 (1%)
 Frame = +3

Query: 18  IISLFILNFLYVTSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQ 185
           ++ LF+L    V  AI F + P   +KCL+EEIHK++LVTG Y+I+D    A G ++ ++
Sbjct: 18  LLLLFLLGPRLVL-AISFHL-PINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSHLK 75

Query: 186 VTDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETK 365
           +TDS  H+LY K+D  KGKFAFTTE+Y+MF+VC E+K  G G+ PD+ V LD+KHGVE K
Sbjct: 76  ITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAK 133

Query: 366 NYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLFS 545
           NY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+FS
Sbjct: 134 NYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFS 193

Query: 546 MACLMGLAIWQVLYLRRYFKSKKLIE 623
           M CL+GLA WQV YLRR+FK+KKLIE
Sbjct: 194 MFCLIGLATWQVFYLRRFFKAKKLIE 219

>sp|Q5RE32|TMEDA_PONPY Transmembrane emp24 domain containing protein 10 precursor
           (Transmembrane protein Tmp21) (21 kDa transmembrane
           trafficking protein)
          Length = 219

 Score =  246 bits (628), Expect = 6e-65
 Identities = 125/206 (60%), Positives = 160/206 (77%), Gaps = 4/206 (1%)
 Frame = +3

Query: 18  IISLFILNFLYVTSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQ 185
           ++ LF+L    V  AI F + P   +KCL+EEIHK++LVTG Y+I+D    A G ++ ++
Sbjct: 18  LLLLFLLGPSLVL-AISFHL-PINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSHLK 75

Query: 186 VTDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETK 365
           +TDS  H+LY K+D  KGKFAFTTE+Y+MF+VC E+K  G G+ PD+ V LD+KHGVE K
Sbjct: 76  ITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAK 133

Query: 366 NYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLFS 545
           NY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM  REE+MRDTNEST+ RV YFS+FS
Sbjct: 134 NYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMEKREEEMRDTNESTNTRVLYFSIFS 193

Query: 546 MACLMGLAIWQVLYLRRYFKSKKLIE 623
           M CL+GLA WQV YLRR+FK+KKLIE
Sbjct: 194 MFCLIGLATWQVFYLRRFFKAKKLIE 219

>sp|Q90515|TMEDA_FUGRU Transmembrane emp24 domain containing protein 10 precursor
           (Transmembrane protein Tmp21) (S31III125)
          Length = 213

 Score =  241 bits (616), Expect = 2e-63
 Identities = 123/209 (58%), Positives = 156/209 (74%), Gaps = 10/209 (4%)
 Frame = +3

Query: 27  LFILNFLYVTSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITD----------APGQKA 176
           LF+   +    +I FF+ P   +KCL+EEIHK+VLVTGEY+I++            G  +
Sbjct: 8   LFLPVLIESAFSISFFL-PVNTRKCLREEIHKDVLVTGEYEISEQVVTVHTSSTVVGDGS 66

Query: 177 SIQVTDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGV 356
             ++TDS SH LY K+D  KGKFAFTTE+Y+MF+VC E+K    G+ PD+ V LD+KHGV
Sbjct: 67  IFKITDSSSHTLYSKEDATKGKFAFTTEDYDMFEVCFESKCT--GRVPDQLVNLDMKHGV 124

Query: 357 ETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFS 536
           E KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS
Sbjct: 125 EAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFS 184

Query: 537 LFSMACLMGLAIWQVLYLRRYFKSKKLIE 623
           +FSM CL+GLA WQV YLRR+FK+KKLIE
Sbjct: 185 IFSMFCLIGLATWQVFYLRRFFKAKKLIE 213

>sp|P54837|ERV25_YEAST Protein ERV25 precursor
          Length = 211

 Score =  134 bits (336), Expect = 5e-31
 Identities = 70/177 (39%), Positives = 111/177 (62%), Gaps = 3/177 (1%)
 Frame = +3

Query: 99  CLKEEIHKNVLVTGEY--DITDAPGQKASIQVTDSKSHVLYQKDDIAKG-KFAFTTEEYE 269
           C+++ + +  LV  +   D +   GQK ++ V DS  +   +K D A   + AFT     
Sbjct: 35  CIRDFVTEGQLVVADIHSDGSVGDGQKLNLFVRDSVGNEYRRKRDFAGDVRVAFTAPSST 94

Query: 270 MFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEI 449
            FDVC E +    G+   R + LDI+ G E ++++ ++  EKLKP+EVEL+R+E+++DEI
Sbjct: 95  AFDVCFENQAQYRGRSLSRAIELDIESGAEARDWNKISANEKLKPIEVELRRVEEITDEI 154

Query: 450 VKDFQYMRDREEKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRYFKSKKLI 620
           V +  Y+++REE++RDTNEST+ RV  FS+  +  L  L +WQV YL+ YFK+K +I
Sbjct: 155 VDELTYLKNREERLRDTNESTNRRVRNFSILVIIVLSSLGVWQVNYLKNYFKTKHII 211

>sp|Q9BVK6|TMED9_HUMAN Transmembrane emp24 domain containing protein 9 precursor
           (Glycoprotein 25L2)
          Length = 214

 Score = 97.8 bits (242), Expect = 4e-20
 Identities = 60/215 (27%), Positives = 109/215 (50%), Gaps = 16/215 (7%)
 Frame = +3

Query: 24  SLFILNFLYVTSAIRFFVTPNGGKKCLKEEIHKNVLVTGEY--DITD---------APGQ 170
           +L ++ +L    +  +F      KKC  EEI    +V G Y   + D          PG 
Sbjct: 3   TLLLVLWLATRGSALYFHIGETEKKCFIEEIPDETMVIGNYRTQLYDKQREEYQPATPGL 62

Query: 171 KASIQVTDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVF 335
              ++V D +  V+  +   ++G+F FT+       +C+ +      L  GG      V 
Sbjct: 63  GMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGM---LRVH 119

Query: 336 LDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTH 515
           LDI+ G    +Y  +A  +KL  L++ +++L +  ++I K+  Y R REE+ R T+EST+
Sbjct: 120 LDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTN 179

Query: 516 NRVFYFSLFSMACLMGLAIWQVLYLRRYFKSKKLI 620
            RV ++S+     L+ + +WQ+ +L+ +F++KKL+
Sbjct: 180 QRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKLV 214

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,976,528
Number of Sequences: 369166
Number of extensions: 1787301
Number of successful extensions: 5774
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5497
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5725
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9078450570
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00007

Planaria EST Database

DrC_00007

BLASTX 2.2.13 [Nov-27-2005]

Cluster detail