Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_O05
(876 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q28735|TMEDA_RABIT Transmembrane emp24 domain containing... 248 2e-65
sp|O35587|TMEDA_MESAU Transmembrane protein Tmp21 precursor... 248 2e-65
sp|Q5E971|TMEDA_BOVIN Transmembrane emp24 domain containing... 248 2e-65
sp|Q9D1D4|TMEDA_MOUSE Transmembrane emp24 domain containing... 247 3e-65
sp|Q63584|TMEDA_RAT Transmembrane emp24 domain containing p... 247 3e-65
sp|P49755|TMEDA_HUMAN Transmembrane emp24 domain containing... 246 5e-65
sp|Q5RE32|TMEDA_PONPY Transmembrane emp24 domain containing... 246 8e-65
sp|Q90515|TMEDA_FUGRU Transmembrane emp24 domain containing... 241 3e-63
sp|P54837|ERV25_YEAST Protein ERV25 precursor 134 4e-31
sp|Q8R1V4|TMED4_MOUSE Transmembrane emp24 domain containing... 97 8e-20
>sp|Q28735|TMEDA_RABIT Transmembrane emp24 domain containing protein 10 precursor
(Transmembrane protein Tmp21) (21 kDa transmembrane
trafficking protein) (Integral membrane protein p23)
Length = 219
Score = 248 bits (633), Expect = 2e-65
Identities = 120/188 (63%), Positives = 151/188 (80%), Gaps = 4/188 (2%)
Frame = +3
Query: 45 FVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDIAKG 212
F P +KCL+EEIHK++LVTG Y+ITD A G + +++TDS H+LY K+D +KG
Sbjct: 34 FHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYSKEDASKG 93
Query: 213 KFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVEL 392
KFAFTTE+Y+MF+VC E+K G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL
Sbjct: 94 KFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVEL 151
Query: 393 KRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRY 572
+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+
Sbjct: 152 RRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRF 211
Query: 573 FKSKKLIE 596
FK+KKLIE
Sbjct: 212 FKAKKLIE 219
>sp|O35587|TMEDA_MESAU Transmembrane protein Tmp21 precursor (21 kDa transmembrane
trafficking protein) (Integral membrane protein p23)
Length = 219
Score = 248 bits (632), Expect = 2e-65
Identities = 120/188 (63%), Positives = 150/188 (79%), Gaps = 4/188 (2%)
Frame = +3
Query: 45 FVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDIAKG 212
F P +KCL+EEIHK++LVTG Y+ITD A G + +++TDS H+LY K+D KG
Sbjct: 34 FHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYAKEDATKG 93
Query: 213 KFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVEL 392
KFAFTTE+Y+MF+VC E+K G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL
Sbjct: 94 KFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVEL 151
Query: 393 KRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRY 572
+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+
Sbjct: 152 RRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMLCLIGLATWQVFYLRRF 211
Query: 573 FKSKKLIE 596
FK+KKLIE
Sbjct: 212 FKAKKLIE 219
>sp|Q5E971|TMEDA_BOVIN Transmembrane emp24 domain containing protein 10 precursor
(Transmembrane protein Tmp21) (21 kDa transmembrane
trafficking protein)
Length = 219
Score = 248 bits (632), Expect = 2e-65
Identities = 120/188 (63%), Positives = 150/188 (79%), Gaps = 4/188 (2%)
Frame = +3
Query: 45 FVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDIAKG 212
F P +KCL+EEIHK++LVTG Y+ITD A G + +++TDS H+LY K+D KG
Sbjct: 34 FHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYSKEDATKG 93
Query: 213 KFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVEL 392
KFAFTTE+Y+MF+VC E+K G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL
Sbjct: 94 KFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVEL 151
Query: 393 KRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRY 572
+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+
Sbjct: 152 RRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRF 211
Query: 573 FKSKKLIE 596
FK+KKLIE
Sbjct: 212 FKAKKLIE 219
>sp|Q9D1D4|TMEDA_MOUSE Transmembrane emp24 domain containing protein 10 precursor
(Transmembrane protein Tmp21) (21 kDa transmembrane
trafficking protein)
Length = 219
Score = 247 bits (631), Expect = 3e-65
Identities = 120/188 (63%), Positives = 150/188 (79%), Gaps = 4/188 (2%)
Frame = +3
Query: 45 FVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDIAKG 212
F P +KCL+EEIHK++LVTG Y+ITD A G + +++TDS H+LY K+D KG
Sbjct: 34 FHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYAKEDATKG 93
Query: 213 KFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVEL 392
KFAFTTE+Y+MF+VC E+K G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL
Sbjct: 94 KFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVEL 151
Query: 393 KRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRY 572
+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+
Sbjct: 152 RRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRF 211
Query: 573 FKSKKLIE 596
FK+KKLIE
Sbjct: 212 FKAKKLIE 219
>sp|Q63584|TMEDA_RAT Transmembrane emp24 domain containing protein 10 precursor
(Transmembrane protein Tmp21) (21 kDa transmembrane
trafficking protein)
Length = 219
Score = 247 bits (631), Expect = 3e-65
Identities = 120/188 (63%), Positives = 150/188 (79%), Gaps = 4/188 (2%)
Frame = +3
Query: 45 FVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDIAKG 212
F P +KCL+EEIHK++LVTG Y+ITD A G + +++TDS H+LY K+D KG
Sbjct: 34 FHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYAKEDATKG 93
Query: 213 KFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVEL 392
KFAFTTE+Y+MF+VC E+K G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL
Sbjct: 94 KFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVEL 151
Query: 393 KRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRY 572
+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+
Sbjct: 152 RRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRF 211
Query: 573 FKSKKLIE 596
FK+KKLIE
Sbjct: 212 FKAKKLIE 219
>sp|P49755|TMEDA_HUMAN Transmembrane emp24 domain containing protein 10 precursor
(Transmembrane protein Tmp21) (21 kDa transmembrane
trafficking protein) (p24delta) (S31III125) (S31I125)
(Tmp-21-I)
Length = 219
Score = 246 bits (629), Expect = 5e-65
Identities = 119/188 (63%), Positives = 151/188 (80%), Gaps = 4/188 (2%)
Frame = +3
Query: 45 FVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDIAKG 212
F P +KCL+EEIHK++LVTG Y+I+D A G ++ +++TDS H+LY K+D KG
Sbjct: 34 FHLPINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSHLKITDSAGHILYSKEDATKG 93
Query: 213 KFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVEL 392
KFAFTTE+Y+MF+VC E+K G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL
Sbjct: 94 KFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVEL 151
Query: 393 KRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRY 572
+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+
Sbjct: 152 RRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRF 211
Query: 573 FKSKKLIE 596
FK+KKLIE
Sbjct: 212 FKAKKLIE 219
>sp|Q5RE32|TMEDA_PONPY Transmembrane emp24 domain containing protein 10 precursor
(Transmembrane protein Tmp21) (21 kDa transmembrane
trafficking protein)
Length = 219
Score = 246 bits (627), Expect = 8e-65
Identities = 119/188 (63%), Positives = 150/188 (79%), Gaps = 4/188 (2%)
Frame = +3
Query: 45 FVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDIAKG 212
F P +KCL+EEIHK++LVTG Y+I+D A G ++ +++TDS H+LY K+D KG
Sbjct: 34 FHLPINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSHLKITDSAGHILYSKEDATKG 93
Query: 213 KFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVEL 392
KFAFTTE+Y+MF+VC E+K G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL
Sbjct: 94 KFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVEL 151
Query: 393 KRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRY 572
+RLEDLS+ IV DF YM REE+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+
Sbjct: 152 RRLEDLSESIVNDFAYMEKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRF 211
Query: 573 FKSKKLIE 596
FK+KKLIE
Sbjct: 212 FKAKKLIE 219
>sp|Q90515|TMEDA_FUGRU Transmembrane emp24 domain containing protein 10 precursor
(Transmembrane protein Tmp21) (S31III125)
Length = 213
Score = 241 bits (614), Expect = 3e-63
Identities = 121/198 (61%), Positives = 152/198 (76%), Gaps = 10/198 (5%)
Frame = +3
Query: 33 AIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITD----------APGQKASIQVTDSKSHV 182
+I FF+ P +KCL+EEIHK+VLVTGEY+I++ G + ++TDS SH
Sbjct: 19 SISFFL-PVNTRKCLREEIHKDVLVTGEYEISEQVVTVHTSSTVVGDGSIFKITDSSSHT 77
Query: 183 LYQKDDIAKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQA 362
LY K+D KGKFAFTTE+Y+MF+VC E+K G + PD+ V LD+KHGVE KNY+ +A+
Sbjct: 78 LYSKEDATKGKFAFTTEDYDMFEVCFESKCTG--RVPDQLVNLDMKHGVEAKNYEEIAKV 135
Query: 363 EKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLFSMACLMGLA 542
EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+FSM CL+GLA
Sbjct: 136 EKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLA 195
Query: 543 IWQVLYLRRYFKSKKLIE 596
WQV YLRR+FK+KKLIE
Sbjct: 196 TWQVFYLRRFFKAKKLIE 213
>sp|P54837|ERV25_YEAST Protein ERV25 precursor
Length = 211
Score = 134 bits (336), Expect = 4e-31
Identities = 70/177 (39%), Positives = 111/177 (62%), Gaps = 3/177 (1%)
Frame = +3
Query: 72 CLKEEIHKNVLVTGEY--DITDAPGQKASIQVTDSKSHVLYQKDDIAKG-KFAFTTEEYE 242
C+++ + + LV + D + GQK ++ V DS + +K D A + AFT
Sbjct: 35 CIRDFVTEGQLVVADIHSDGSVGDGQKLNLFVRDSVGNEYRRKRDFAGDVRVAFTAPSST 94
Query: 243 MFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEI 422
FDVC E + G+ R + LDI+ G E ++++ ++ EKLKP+EVEL+R+E+++DEI
Sbjct: 95 AFDVCFENQAQYRGRSLSRAIELDIESGAEARDWNKISANEKLKPIEVELRRVEEITDEI 154
Query: 423 VKDFQYMRDREEKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRYFKSKKLI 593
V + Y+++REE++RDTNEST+ RV FS+ + L L +WQV YL+ YFK+K +I
Sbjct: 155 VDELTYLKNREERLRDTNESTNRRVRNFSILVIIVLSSLGVWQVNYLKNYFKTKHII 211
>sp|Q8R1V4|TMED4_MOUSE Transmembrane emp24 domain containing protein 4 precursor (p26)
Length = 227
Score = 96.7 bits (239), Expect = 8e-20
Identities = 59/192 (30%), Positives = 97/192 (50%), Gaps = 16/192 (8%)
Frame = +3
Query: 66 KKCLKEEIHKNVLVTGEYD-----------ITDAPGQKASIQVTDSKSHVLYQKDDIAKG 212
K+C EEI +V G Y + PG ++V D V+ + ++G
Sbjct: 39 KRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEG 98
Query: 213 KFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKP 377
+F FT+ +C+ + L GGK V LDI+ G NY +A +KL
Sbjct: 99 RFTFTSHTPGDHQICLHSNSTRMALFAGGK---LRVHLDIQVGEHANNYPEIAAKDKLTE 155
Query: 378 LEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVL 557
L++ ++L D ++I K+ Y R REE+ R T+EST+ RV ++S+ L+ IWQ+
Sbjct: 156 LQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMR 215
Query: 558 YLRRYFKSKKLI 593
+L+ +F++KKL+
Sbjct: 216 HLKSFFEAKKLV 227
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,529,652
Number of Sequences: 369166
Number of extensions: 1718012
Number of successful extensions: 5544
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5299
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5499
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8694177530
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)