Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_025_I24 (611 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O35587|TMEDA_MESAU Transmembrane protein Tmp21 precursor... 161 1e-39 sp|Q9D1D4|TMEDA_MOUSE Transmembrane emp24 domain containing... 160 2e-39 sp|P49755|TMEDA_HUMAN Transmembrane emp24 domain containing... 160 2e-39 sp|Q63584|TMEDA_RAT Transmembrane emp24 domain containing p... 160 2e-39 sp|Q28735|TMEDA_RABIT Transmembrane emp24 domain containing... 160 2e-39 sp|Q5E971|TMEDA_BOVIN Transmembrane emp24 domain containing... 160 2e-39 sp|Q5RE32|TMEDA_PONPY Transmembrane emp24 domain containing... 160 3e-39 sp|Q90515|TMEDA_FUGRU Transmembrane emp24 domain containing... 158 9e-39 sp|P54837|ERV25_YEAST Protein ERV25 precursor 109 5e-24 sp|Q8R1V4|TMED4_MOUSE Transmembrane emp24 domain containing... 77 5e-14
>sp|O35587|TMEDA_MESAU Transmembrane protein Tmp21 precursor (21 kDa transmembrane trafficking protein) (Integral membrane protein p23) Length = 219 Score = 161 bits (407), Expect = 1e-39 Identities = 76/107 (71%), Positives = 91/107 (85%) Frame = +1 Query: 13 GGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDRE 192 G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ RE Sbjct: 113 GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKRE 172 Query: 193 EKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRYFKSKKLIE 333 E+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+FK+KKLIE Sbjct: 173 EEMRDTNESTNTRVLYFSIFSMLCLIGLATWQVFYLRRFFKAKKLIE 219
>sp|Q9D1D4|TMEDA_MOUSE Transmembrane emp24 domain containing protein 10 precursor (Transmembrane protein Tmp21) (21 kDa transmembrane trafficking protein) Length = 219 Score = 160 bits (406), Expect = 2e-39 Identities = 76/107 (71%), Positives = 91/107 (85%) Frame = +1 Query: 13 GGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDRE 192 G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ RE Sbjct: 113 GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKRE 172 Query: 193 EKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRYFKSKKLIE 333 E+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+FK+KKLIE Sbjct: 173 EEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE 219
>sp|P49755|TMEDA_HUMAN Transmembrane emp24 domain containing protein 10 precursor (Transmembrane protein Tmp21) (21 kDa transmembrane trafficking protein) (p24delta) (S31III125) (S31I125) (Tmp-21-I) Length = 219 Score = 160 bits (406), Expect = 2e-39 Identities = 76/107 (71%), Positives = 91/107 (85%) Frame = +1 Query: 13 GGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDRE 192 G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ RE Sbjct: 113 GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKRE 172 Query: 193 EKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRYFKSKKLIE 333 E+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+FK+KKLIE Sbjct: 173 EEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE 219
>sp|Q63584|TMEDA_RAT Transmembrane emp24 domain containing protein 10 precursor (Transmembrane protein Tmp21) (21 kDa transmembrane trafficking protein) Length = 219 Score = 160 bits (406), Expect = 2e-39 Identities = 76/107 (71%), Positives = 91/107 (85%) Frame = +1 Query: 13 GGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDRE 192 G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ RE Sbjct: 113 GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKRE 172 Query: 193 EKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRYFKSKKLIE 333 E+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+FK+KKLIE Sbjct: 173 EEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE 219
>sp|Q28735|TMEDA_RABIT Transmembrane emp24 domain containing protein 10 precursor (Transmembrane protein Tmp21) (21 kDa transmembrane trafficking protein) (Integral membrane protein p23) Length = 219 Score = 160 bits (406), Expect = 2e-39 Identities = 76/107 (71%), Positives = 91/107 (85%) Frame = +1 Query: 13 GGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDRE 192 G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ RE Sbjct: 113 GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKRE 172 Query: 193 EKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRYFKSKKLIE 333 E+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+FK+KKLIE Sbjct: 173 EEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE 219
>sp|Q5E971|TMEDA_BOVIN Transmembrane emp24 domain containing protein 10 precursor (Transmembrane protein Tmp21) (21 kDa transmembrane trafficking protein) Length = 219 Score = 160 bits (406), Expect = 2e-39 Identities = 76/107 (71%), Positives = 91/107 (85%) Frame = +1 Query: 13 GGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDRE 192 G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ RE Sbjct: 113 GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKRE 172 Query: 193 EKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRYFKSKKLIE 333 E+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+FK+KKLIE Sbjct: 173 EEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE 219
>sp|Q5RE32|TMEDA_PONPY Transmembrane emp24 domain containing protein 10 precursor (Transmembrane protein Tmp21) (21 kDa transmembrane trafficking protein) Length = 219 Score = 160 bits (404), Expect = 3e-39 Identities = 76/107 (71%), Positives = 90/107 (84%) Frame = +1 Query: 13 GGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDRE 192 G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM RE Sbjct: 113 GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMEKRE 172 Query: 193 EKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRYFKSKKLIE 333 E+MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+FK+KKLIE Sbjct: 173 EEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE 219
>sp|Q90515|TMEDA_FUGRU Transmembrane emp24 domain containing protein 10 precursor (Transmembrane protein Tmp21) (S31III125) Length = 213 Score = 158 bits (400), Expect = 9e-39 Identities = 75/105 (71%), Positives = 90/105 (85%) Frame = +1 Query: 19 GKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEK 198 G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+ Sbjct: 109 GRVPDQLVNLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEE 168 Query: 199 MRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRYFKSKKLIE 333 MRDTNEST+ RV YFS+FSM CL+GLA WQV YLRR+FK+KKLIE Sbjct: 169 MRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE 213
>sp|P54837|ERV25_YEAST Protein ERV25 precursor Length = 211 Score = 109 bits (273), Expect = 5e-24 Identities = 49/104 (47%), Positives = 77/104 (74%) Frame = +1 Query: 19 GKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEK 198 G+ R + LDI+ G E ++++ ++ EKLKP+EVEL+R+E+++DEIV + Y+++REE+ Sbjct: 108 GRSLSRAIELDIESGAEARDWNKISANEKLKPIEVELRRVEEITDEIVDELTYLKNREER 167 Query: 199 MRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRYFKSKKLI 330 +RDTNEST+ RV FS+ + L L +WQV YL+ YFK+K +I Sbjct: 168 LRDTNESTNRRVRNFSILVIIVLSSLGVWQVNYLKNYFKTKHII 211
>sp|Q8R1V4|TMED4_MOUSE Transmembrane emp24 domain containing protein 4 precursor (p26) Length = 227 Score = 76.6 bits (187), Expect = 5e-14 Identities = 41/108 (37%), Positives = 65/108 (60%) Frame = +1 Query: 7 LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRD 186 L GGK V LDI+ G NY +A +KL L++ ++L D ++I K+ Y R Sbjct: 123 LFAGGK---LRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRY 179 Query: 187 REEKMRDTNESTHNRVFYFSLFSMACLMGLAIWQVLYLRRYFKSKKLI 330 REE+ R T+EST+ RV ++S+ L+ IWQ+ +L+ +F++KKL+ Sbjct: 180 REERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV 227
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 65,447,728 Number of Sequences: 369166 Number of extensions: 1133563 Number of successful extensions: 3969 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3827 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3957 length of database: 68,354,980 effective HSP length: 105 effective length of database: 48,957,805 effective search space used: 4797864890 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)