Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_D19
(728 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q28735|TMEDA_RABIT Transmembrane emp24 domain containing... 207 2e-53
sp|P49755|TMEDA_HUMAN Transmembrane emp24 domain containing... 207 3e-53
sp|O35587|TMEDA_MESAU Transmembrane protein Tmp21 precursor... 207 3e-53
sp|Q5E971|TMEDA_BOVIN Transmembrane emp24 domain containing... 207 3e-53
sp|Q9D1D4|TMEDA_MOUSE Transmembrane emp24 domain containing... 206 4e-53
sp|Q63584|TMEDA_RAT Transmembrane emp24 domain containing p... 206 4e-53
sp|Q5RE32|TMEDA_PONPY Transmembrane emp24 domain containing... 206 5e-53
sp|Q90515|TMEDA_FUGRU Transmembrane emp24 domain containing... 204 3e-52
sp|P54837|ERV25_YEAST Protein ERV25 precursor 122 7e-28
sp|Q9BVK6|TMED9_HUMAN Transmembrane emp24 domain containing... 83 9e-16
>sp|Q28735|TMEDA_RABIT Transmembrane emp24 domain containing protein 10 precursor
(Transmembrane protein Tmp21) (21 kDa transmembrane
trafficking protein) (Integral membrane protein p23)
Length = 219
Score = 207 bits (527), Expect = 2e-53
Identities = 98/148 (66%), Positives = 124/148 (83%)
Frame = +1
Query: 7 IQVTDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVE 186
+++TDS H+LY K+D +KGKFAFTTE+Y+MF+VC E+K G G+ PD+ V LD+KHGVE
Sbjct: 74 LKITDSAGHILYSKEDASKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVE 131
Query: 187 TKSDDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSL 366
K+ + +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+
Sbjct: 132 AKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSI 191
Query: 367 FSMACLMGLAIWQVLYLRRYFKSKKLIE 450
FSM CL+GLA WQV YLRR+FK+KKLIE
Sbjct: 192 FSMFCLIGLATWQVFYLRRFFKAKKLIE 219
>sp|P49755|TMEDA_HUMAN Transmembrane emp24 domain containing protein 10 precursor
(Transmembrane protein Tmp21) (21 kDa transmembrane
trafficking protein) (p24delta) (S31III125) (S31I125)
(Tmp-21-I)
Length = 219
Score = 207 bits (526), Expect = 3e-53
Identities = 98/148 (66%), Positives = 123/148 (83%)
Frame = +1
Query: 7 IQVTDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVE 186
+++TDS H+LY K+D KGKFAFTTE+Y+MF+VC E+K G G+ PD+ V LD+KHGVE
Sbjct: 74 LKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVE 131
Query: 187 TKSDDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSL 366
K+ + +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+
Sbjct: 132 AKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSI 191
Query: 367 FSMACLMGLAIWQVLYLRRYFKSKKLIE 450
FSM CL+GLA WQV YLRR+FK+KKLIE
Sbjct: 192 FSMFCLIGLATWQVFYLRRFFKAKKLIE 219
>sp|O35587|TMEDA_MESAU Transmembrane protein Tmp21 precursor (21 kDa transmembrane
trafficking protein) (Integral membrane protein p23)
Length = 219
Score = 207 bits (526), Expect = 3e-53
Identities = 98/148 (66%), Positives = 123/148 (83%)
Frame = +1
Query: 7 IQVTDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVE 186
+++TDS H+LY K+D KGKFAFTTE+Y+MF+VC E+K G G+ PD+ V LD+KHGVE
Sbjct: 74 LKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVE 131
Query: 187 TKSDDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSL 366
K+ + +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+
Sbjct: 132 AKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSI 191
Query: 367 FSMACLMGLAIWQVLYLRRYFKSKKLIE 450
FSM CL+GLA WQV YLRR+FK+KKLIE
Sbjct: 192 FSMLCLIGLATWQVFYLRRFFKAKKLIE 219
>sp|Q5E971|TMEDA_BOVIN Transmembrane emp24 domain containing protein 10 precursor
(Transmembrane protein Tmp21) (21 kDa transmembrane
trafficking protein)
Length = 219
Score = 207 bits (526), Expect = 3e-53
Identities = 98/148 (66%), Positives = 123/148 (83%)
Frame = +1
Query: 7 IQVTDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVE 186
+++TDS H+LY K+D KGKFAFTTE+Y+MF+VC E+K G G+ PD+ V LD+KHGVE
Sbjct: 74 LKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVE 131
Query: 187 TKSDDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSL 366
K+ + +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+
Sbjct: 132 AKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSI 191
Query: 367 FSMACLMGLAIWQVLYLRRYFKSKKLIE 450
FSM CL+GLA WQV YLRR+FK+KKLIE
Sbjct: 192 FSMFCLIGLATWQVFYLRRFFKAKKLIE 219
>sp|Q9D1D4|TMEDA_MOUSE Transmembrane emp24 domain containing protein 10 precursor
(Transmembrane protein Tmp21) (21 kDa transmembrane
trafficking protein)
Length = 219
Score = 206 bits (525), Expect = 4e-53
Identities = 98/148 (66%), Positives = 123/148 (83%)
Frame = +1
Query: 7 IQVTDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVE 186
+++TDS H+LY K+D KGKFAFTTE+Y+MF+VC E+K G G+ PD+ V LD+KHGVE
Sbjct: 74 LKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVE 131
Query: 187 TKSDDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSL 366
K+ + +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+
Sbjct: 132 AKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSI 191
Query: 367 FSMACLMGLAIWQVLYLRRYFKSKKLIE 450
FSM CL+GLA WQV YLRR+FK+KKLIE
Sbjct: 192 FSMFCLIGLATWQVFYLRRFFKAKKLIE 219
>sp|Q63584|TMEDA_RAT Transmembrane emp24 domain containing protein 10 precursor
(Transmembrane protein Tmp21) (21 kDa transmembrane
trafficking protein)
Length = 219
Score = 206 bits (525), Expect = 4e-53
Identities = 98/148 (66%), Positives = 123/148 (83%)
Frame = +1
Query: 7 IQVTDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVE 186
+++TDS H+LY K+D KGKFAFTTE+Y+MF+VC E+K G G+ PD+ V LD+KHGVE
Sbjct: 74 LKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVE 131
Query: 187 TKSDDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSL 366
K+ + +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+
Sbjct: 132 AKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSI 191
Query: 367 FSMACLMGLAIWQVLYLRRYFKSKKLIE 450
FSM CL+GLA WQV YLRR+FK+KKLIE
Sbjct: 192 FSMFCLIGLATWQVFYLRRFFKAKKLIE 219
>sp|Q5RE32|TMEDA_PONPY Transmembrane emp24 domain containing protein 10 precursor
(Transmembrane protein Tmp21) (21 kDa transmembrane
trafficking protein)
Length = 219
Score = 206 bits (524), Expect = 5e-53
Identities = 98/148 (66%), Positives = 122/148 (82%)
Frame = +1
Query: 7 IQVTDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVE 186
+++TDS H+LY K+D KGKFAFTTE+Y+MF+VC E+K G G+ PD+ V LD+KHGVE
Sbjct: 74 LKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVE 131
Query: 187 TKSDDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSL 366
K+ + +A+ EKLKPLEVEL+RLEDLS+ IV DF YM REE+MRDTNEST+ RV YFS+
Sbjct: 132 AKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMEKREEEMRDTNESTNTRVLYFSI 191
Query: 367 FSMACLMGLAIWQVLYLRRYFKSKKLIE 450
FSM CL+GLA WQV YLRR+FK+KKLIE
Sbjct: 192 FSMFCLIGLATWQVFYLRRFFKAKKLIE 219
>sp|Q90515|TMEDA_FUGRU Transmembrane emp24 domain containing protein 10 precursor
(Transmembrane protein Tmp21) (S31III125)
Length = 213
Score = 204 bits (518), Expect = 3e-52
Identities = 98/147 (66%), Positives = 121/147 (82%)
Frame = +1
Query: 10 QVTDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVET 189
++TDS SH LY K+D KGKFAFTTE+Y+MF+VC E+K G + PD+ V LD+KHGVE
Sbjct: 69 KITDSSSHTLYSKEDATKGKFAFTTEDYDMFEVCFESKCTG--RVPDQLVNLDMKHGVEA 126
Query: 190 KSDDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLF 369
K+ + +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFS+F
Sbjct: 127 KNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIF 186
Query: 370 SMACLMGLAIWQVLYLRRYFKSKKLIE 450
SM CL+GLA WQV YLRR+FK+KKLIE
Sbjct: 187 SMFCLIGLATWQVFYLRRFFKAKKLIE 213
>sp|P54837|ERV25_YEAST Protein ERV25 precursor
Length = 211
Score = 122 bits (307), Expect = 7e-28
Identities = 63/146 (43%), Positives = 93/146 (63%), Gaps = 1/146 (0%)
Frame = +1
Query: 13 VTDSKSHVLYQKDDIAKG-KFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVET 189
V DS + +K D A + AFT FDVC E + G+ R + LDI+ G E
Sbjct: 66 VRDSVGNEYRRKRDFAGDVRVAFTAPSSTAFDVCFENQAQYRGRSLSRAIELDIESGAEA 125
Query: 190 KSDDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSLF 369
+ + ++ EKLKP+EVEL+R+E+++DEIV + Y+++REE++RDTNEST+ RV FS+
Sbjct: 126 RDWNKISANEKLKPIEVELRRVEEITDEIVDELTYLKNREERLRDTNESTNRRVRNFSIL 185
Query: 370 SMACLMGLAIWQVLYLRRYFKSKKLI 447
+ L L +WQV YL+ YFK+K +I
Sbjct: 186 VIIVLSSLGVWQVNYLKNYFKTKHII 211
>sp|Q9BVK6|TMED9_HUMAN Transmembrane emp24 domain containing protein 9 precursor
(Glycoprotein 25L2)
Length = 214
Score = 82.8 bits (203), Expect = 9e-16
Identities = 44/152 (28%), Positives = 84/152 (55%), Gaps = 5/152 (3%)
Frame = +1
Query: 7 IQVTDSKSHVLYQKDDIAKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDI 171
++V D + V+ + ++G+F FT+ +C+ + L GG V LDI
Sbjct: 66 VEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGM---LRVHLDI 122
Query: 172 KHGVETKSDDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRV 351
+ G +A +KL L++ +++L + ++I K+ Y R REE+ R T+EST+ RV
Sbjct: 123 QVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRV 182
Query: 352 FYFSLFSMACLMGLAIWQVLYLRRYFKSKKLI 447
++S+ L+ + +WQ+ +L+ +F++KKL+
Sbjct: 183 LWWSILQTLILVAIGVWQMRHLKSFFEAKKLV 214
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,611,654
Number of Sequences: 369166
Number of extensions: 1432726
Number of successful extensions: 5100
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4874
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5073
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6486082400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)