Planaria EST Database


DrC_01081

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01081
         (1436 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q16543|CDC37_HUMAN  Hsp90 co-chaperone Cdc37 (Hsp90 chape...   359   1e-98
sp|Q61081|CDC37_MOUSE  Hsp90 co-chaperone Cdc37 (Hsp90 chape...   355   2e-97
sp|Q63692|CDC37_RAT  Hsp90 co-chaperone Cdc37 (Hsp90 chapero...   355   2e-97
sp|Q9DGQ7|CDC37_TETFL  Hsp90 co-chaperone Cdc37 (Hsp90 chape...   353   7e-97
sp|O57476|CDC37_CHICK  Hsp90 co-chaperone Cdc37 (Hsp90 chape...   353   9e-97
sp|Q24740|CDC37_DROVI  Hsp90 co-chaperone Cdc37 (Hsp90 chape...   339   1e-92
sp|Q24276|CDC37_DROME  Hsp90 co-chaperone Cdc37 (Hsp90 chape...   334   3e-91
sp|O02108|CDC37_CAEEL  Probable Hsp90 co-chaperone Cdc37 (Hs...   238   3e-62
sp|Q8X1E6|CDC37_CANAL  Hsp90 co-chaperone Cdc37 (Hsp90 chape...    65   5e-10
sp|P06101|CDC37_YEAST  Hsp90 co-chaperone Cdc37 (Hsp90 chape...    60   2e-08
>sp|Q16543|CDC37_HUMAN Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
            subunit) (p50Cdc37)
          Length = 378

 Score =  359 bits (922), Expect = 1e-98
 Identities = 174/360 (48%), Positives = 246/360 (68%), Gaps = 2/360 (0%)
 Frame = +2

Query: 20   IDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLTNI 199
            +DYS WDHIEVSDDED+THPNIDT SLFRWRH+ARVER ++F  EK ++++  +E    +
Sbjct: 2    VDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKV 61

Query: 200  QNTRDKIKSAE--ENNNEIASKLKEELRKLETDFDEFNKKRDEFLSKEKRRPWNVDSICK 373
               + K+K  E  E       +L+ E ++L  +   + +K +E   KEK  PWNVD++ K
Sbjct: 62   AECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSK 121

Query: 374  EGKTKTIINSFDTQEKPVNEKDVVDRMKAFVEKYDDDIKKYGLFRKVEEMERFLMKNPHL 553
            +G +K+++N+   + +  +E+    + K FVEKY+  IK +G+ R+ ++ +++L  N HL
Sbjct: 122  DGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHL 181

Query: 554  VCEDTANHLVIWCIDLAVEEKTNLMEHVSHQCIVMQFILELAKSLKRDPRDCIKPFFAKF 733
            VCE+TAN+LVIWCIDL VEEK  LME V+HQ IVMQFILELAKSLK DPR C + FF K 
Sbjct: 182  VCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKI 241

Query: 734  RSQEPEYQTAFTSELDXXXXXXXXXXXXXXXXXMAKIEEEERQKRLGPGGLDPVEVFANL 913
            ++ + +Y   F  EL+                 M + EEEER+KRLGPGGLDPVEV+ +L
Sbjct: 242  KTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYESL 301

Query: 914  PKELQECFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEASG 1093
            P+ELQ+CF+ K+++MLQ+A+SKMDP +A+ H+Q+CIDSG+W+PN+      EA E E +G
Sbjct: 302  PEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKA---SEAKEGEEAG 358
>sp|Q61081|CDC37_MOUSE Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
            subunit) (p50Cdc37)
          Length = 379

 Score =  355 bits (911), Expect = 2e-97
 Identities = 171/361 (47%), Positives = 250/361 (69%), Gaps = 3/361 (0%)
 Frame = +2

Query: 20   IDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLTNI 199
            +DYS WDHIEVSDDED+THPNIDT SLFRWRH+ARVER ++F  EK ++++  +E    +
Sbjct: 2    VDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKV 61

Query: 200  QNTRDKIKSAE--ENNNEIA-SKLKEELRKLETDFDEFNKKRDEFLSKEKRRPWNVDSIC 370
               + K+K  E  E++ ++   +L+ E ++L  +   + +K ++   KEK  PWNVD++ 
Sbjct: 62   AECQRKLKELEVAESDGQVELERLRAEAQQLRKEERSWEQKLEDMRKKEKNMPWNVDTLS 121

Query: 371  KEGKTKTIINSFDTQEKPVNEKDVVDRMKAFVEKYDDDIKKYGLFRKVEEMERFLMKNPH 550
            K+G +K+++N+   + +  +E+    + K FVEKY+  IK +G+  + ++ +++L  N H
Sbjct: 122  KDGFSKSMVNTKPEKAEEDSEEAREQKHKTFVEKYEKQIKHFGMLHRWDDSQKYLSDNVH 181

Query: 551  LVCEDTANHLVIWCIDLAVEEKTNLMEHVSHQCIVMQFILELAKSLKRDPRDCIKPFFAK 730
            LVCE+TAN+LVIWCIDL VEEK  LME V+HQ +VMQFILELAKSLK DPR C + FF K
Sbjct: 182  LVCEETANYLVIWCIDLEVEEKCALMEQVAHQTMVMQFILELAKSLKVDPRACFRQFFTK 241

Query: 731  FRSQEPEYQTAFTSELDXXXXXXXXXXXXXXXXXMAKIEEEERQKRLGPGGLDPVEVFAN 910
             ++ + +Y   F  EL+                 M + EEEER+KRLGPGGLDPVEV+ +
Sbjct: 242  IKTADHQYMEGFKYELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYES 301

Query: 911  LPKELQECFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEAS 1090
            LP+ELQ+CF+ K+++MLQ+A+SKMDP +A+ H+Q+CIDSG+W+PN+    + EA E E +
Sbjct: 302  LPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSK---SGEAKEGEEA 358

Query: 1091 G 1093
            G
Sbjct: 359  G 359
>sp|Q63692|CDC37_RAT Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
            subunit) (p50Cdc37)
          Length = 379

 Score =  355 bits (910), Expect = 2e-97
 Identities = 171/361 (47%), Positives = 248/361 (68%), Gaps = 3/361 (0%)
 Frame = +2

Query: 20   IDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLTNI 199
            +DYS WDHIEVSDDED+THPNIDT SLFRWRH+ARVER ++F  EK ++++  +E    +
Sbjct: 2    VDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKV 61

Query: 200  QNTRDKIKSAE--ENNNEIA-SKLKEELRKLETDFDEFNKKRDEFLSKEKRRPWNVDSIC 370
               + K+K  E  E   ++   +L+ E ++L  +   + +K ++   KEK  PWNVD++ 
Sbjct: 62   AECQRKLKELEVAEGGGQVELERLRAEAQQLRKEERSWEQKLEDMRKKEKNMPWNVDTLS 121

Query: 371  KEGKTKTIINSFDTQEKPVNEKDVVDRMKAFVEKYDDDIKKYGLFRKVEEMERFLMKNPH 550
            K+G +K+++N+   + +  +E+    + K FVEKY+  IK +G+  + ++ +++L  N H
Sbjct: 122  KDGFSKSMVNTKPEKAEEDSEEAREQKHKTFVEKYEKQIKHFGMLHRWDDSQKYLSDNVH 181

Query: 551  LVCEDTANHLVIWCIDLAVEEKTNLMEHVSHQCIVMQFILELAKSLKRDPRDCIKPFFAK 730
            LVCE+TAN+LVIWCIDL VEEK  LME V+HQ +VMQFILELAKSLK DPR C + FF K
Sbjct: 182  LVCEETANYLVIWCIDLEVEEKCALMEQVAHQTMVMQFILELAKSLKVDPRACFRQFFTK 241

Query: 731  FRSQEPEYQTAFTSELDXXXXXXXXXXXXXXXXXMAKIEEEERQKRLGPGGLDPVEVFAN 910
             ++ + +Y   F  EL+                 M + EEEER+KRLGPGGLDPVEV+ +
Sbjct: 242  IKTADQQYMEGFKYELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYES 301

Query: 911  LPKELQECFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEAS 1090
            LP+ELQ+CF+ K+++MLQ+A+SKMDP +A+ H+Q+CIDSG+W+PN+    + EA E E +
Sbjct: 302  LPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSK---SGEAKEGEEA 358

Query: 1091 G 1093
            G
Sbjct: 359  G 359
>sp|Q9DGQ7|CDC37_TETFL Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
            subunit) (p50Cdc37)
          Length = 377

 Score =  353 bits (906), Expect = 7e-97
 Identities = 175/364 (48%), Positives = 248/364 (68%), Gaps = 5/364 (1%)
 Frame = +2

Query: 20   IDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLTNI 199
            IDYS WDHIEVSDDED +HPNIDTPSLFRWRH+ARVER ++F  + +D+ K  +E    +
Sbjct: 4    IDYSVWDHIEVSDDEDVSHPNIDTPSLFRWRHQARVERMEDFKKKGDDLNKGLQECRRKL 63

Query: 200  QNTRDKIK----SAEENNNEIASKLKEELRKLETDFDEFNKKRDEFLSKEKRRPWNVDSI 367
               + K++    SA  +     +K + E +KL+ +  ++ +K +E   +EK+ PWNVD++
Sbjct: 64   AEAQKKVRELSISAAGDAKAELTKTQTEEKKLKKEERDWARKLEEHNHEEKKMPWNVDTL 123

Query: 368  CKEGKTKTIIN-SFDTQEKPVNEKDVVDRMKAFVEKYDDDIKKYGLFRKVEEMERFLMKN 544
             K+G +K+I+N   D+ E    EK+   + K FVE+Y+  IK +G+  + ++ +R+L  N
Sbjct: 124  SKDGFSKSIVNVKADSAEDTEEEKE--KKHKTFVERYEKQIKHFGMLHRWDDSQRYLSDN 181

Query: 545  PHLVCEDTANHLVIWCIDLAVEEKTNLMEHVSHQCIVMQFILELAKSLKRDPRDCIKPFF 724
            P LVCE+TAN+LVI CIDL VEEK  LME V+HQ IVMQFILELAKSLK DPR C + FF
Sbjct: 182  PDLVCEETANYLVIMCIDLEVEEKHALMEQVAHQTIVMQFILELAKSLKVDPRGCFRQFF 241

Query: 725  AKFRSQEPEYQTAFTSELDXXXXXXXXXXXXXXXXXMAKIEEEERQKRLGPGGLDPVEVF 904
             K ++ + +YQ AF  EL+                 M + EEEERQKRLGPGGLDPVEV+
Sbjct: 242  EKIKTADQQYQDAFNDELESFKERVRGRAKIRIEKAMKEYEEEERQKRLGPGGLDPVEVY 301

Query: 905  ANLPKELQECFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESE 1084
             +LP E+Q+CF++K+I+MLQ+ ++KMDP EA+ H+++CIDSG+W+PN+   ++DE  +  
Sbjct: 302  ESLPPEMQKCFDEKDIQMLQDVITKMDPTEAKAHMKRCIDSGLWVPNSKMDESDEKEDGS 361

Query: 1085 ASGE 1096
               E
Sbjct: 362  TYEE 365
>sp|O57476|CDC37_CHICK Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
            subunit) (p50Cdc37)
          Length = 393

 Score =  353 bits (905), Expect = 9e-97
 Identities = 175/371 (47%), Positives = 243/371 (65%), Gaps = 8/371 (2%)
 Frame = +2

Query: 20   IDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLTNI 199
            +DYS WDHIEVSDDED+THPNIDT SLFRWRH+ARVER ++F  EK +++K  +E    +
Sbjct: 2    VDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDKGCRECKRKL 61

Query: 200  QNTRDKIKSAEENNNEIAS--------KLKEELRKLETDFDEFNKKRDEFLSKEKRRPWN 355
               + K+K  E       S        +L+ E ++L  +   +  K +E   KEK  PWN
Sbjct: 62   AECQKKLKELEVAEPGGGSGGGRGERERLQAEAQQLRHEERNWESKMEELRKKEKNMPWN 121

Query: 356  VDSICKEGKTKTIINSFDTQEKPVNEKDVVDRMKAFVEKYDDDIKKYGLFRKVEEMERFL 535
            V ++ K+G +K++ N    +EK   E+    + K FVE+++  IK +G+ R+ ++ +++L
Sbjct: 122  VHTLSKDGFSKSVFN-VKAEEKEETEEQKEQKHKTFVERHEKQIKHFGMLRRWDDSQKYL 180

Query: 536  MKNPHLVCEDTANHLVIWCIDLAVEEKTNLMEHVSHQCIVMQFILELAKSLKRDPRDCIK 715
              NPHLVCE+TAN+LVIWCIDL VEEK  LME V+HQ IVMQFILELAKSLK DPR C +
Sbjct: 181  SDNPHLVCEETANYLVIWCIDLEVEEKQALMEQVAHQTIVMQFILELAKSLKVDPRACFR 240

Query: 716  PFFAKFRSQEPEYQTAFTSELDXXXXXXXXXXXXXXXXXMAKIEEEERQKRLGPGGLDPV 895
             FF K ++ + +Y   F  EL+                 M + EEEERQKRLGPGGLDPV
Sbjct: 241  QFFTKIKTADQQYMEGFNDELEAFKERVRGRAKARIERAMREYEEEERQKRLGPGGLDPV 300

Query: 896  EVFANLPKELQECFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEAN 1075
            +V+ +LP ELQ+CF+ K+++MLQ+ +S+MDP EA+ H+Q+CIDSG+W+PNA K   +   
Sbjct: 301  DVYESLPPELQKCFDAKDVQMLQDTISRMDPTEAKYHMQRCIDSGLWVPNA-KAAAEGGG 359

Query: 1076 ESEASGEYGNA 1108
            +  A G+ G A
Sbjct: 360  QGGAHGQPGGA 370
>sp|Q24740|CDC37_DROVI Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
            subunit)
          Length = 399

 Score =  339 bits (870), Expect = 1e-92
 Identities = 166/363 (45%), Positives = 247/363 (68%), Gaps = 6/363 (1%)
 Frame = +2

Query: 20   IDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLTNI 199
            +DYS+W +IE+SDDED+THPNIDTPSLFRWRH+ARVER  E   EK +++K  + +   +
Sbjct: 2    VDYSKWKNIEISDDEDETHPNIDTPSLFRWRHQARVERMAESEKEKEELKKKRQSYQARL 61

Query: 200  QNTRDKIKSAEENNNEIASKLKEELRKLETDFDEFNKKRDEFLSKEKRRPWNVDSICKEG 379
             N ++ I   E   +E+A  LK+EL K+E +  E +++ +E L +EK+ PWNVD+I K G
Sbjct: 62   INVKELISKKE--GDEVA--LKKELEKIENEGKELDRQENELLKREKKTPWNVDTISKPG 117

Query: 380  KTKTIINSFDTQE--KPVNEKDVVDRMKAFVEKYDDDIKKYGLFRKVEEMERFLMKNPHL 553
              KT+IN    ++  + + E++   RMK FV++ +   K+YG+ RK ++ +RFL ++  L
Sbjct: 118  FEKTVINKKPPRKAAEDLTEEEREQRMKQFVKENEKLCKQYGMLRKYDDSKRFLQEHLDL 177

Query: 554  VCEDTANHLVIWCIDLAVEEKTNLMEHVSHQCIVMQFILELAKSLKRDPRDCIKPFFAKF 733
            VCE+TAN+LVIW I+L +EEK +LM HV+HQCI MQ+ILELAK L  DPR C+  FF+K 
Sbjct: 178  VCEETANYLVIWSINLEMEEKHDLMAHVAHQCICMQYILELAKQLDVDPRACVSSFFSKI 237

Query: 734  RSQEPEYQTAFTSELDXXXXXXXXXXXXXXXXXMAKIEEEERQKRLGPGGLDPVEVFANL 913
            +   PEY+  F SE++                 MA++EEEE+Q+R+GPGGLDP +VF +L
Sbjct: 238  QQCVPEYRQQFESEIEGFKERIQKRAQEKLQEAMAQLEEEEKQERMGPGGLDPADVFESL 297

Query: 914  PKELQECFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANK----KDNDEANES 1081
            P+EL+ CFE ++IE+LQ+ ++ M   +A+ H+++C+DSG+W+PNA       D  EA + 
Sbjct: 298  PEELKACFESRDIELLQKTIATMPVDQAKYHMKRCVDSGLWVPNAADVQLGNDETEAKDD 357

Query: 1082 EAS 1090
            E +
Sbjct: 358  ETT 360
>sp|Q24276|CDC37_DROME Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
            subunit) (Enhancer of sevenless 3B)
          Length = 389

 Score =  334 bits (857), Expect = 3e-91
 Identities = 164/364 (45%), Positives = 247/364 (67%), Gaps = 3/364 (0%)
 Frame = +2

Query: 20   IDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLTNI 199
            +DYS+W +IE+SDDEDDTHPNIDTPSLFRWRH+ARVER  E + EK++++K  + +   +
Sbjct: 2    VDYSKWKNIEISDDEDDTHPNIDTPSLFRWRHQARVERMAEMDHEKDELKKKRQSYQARL 61

Query: 200  QNTRDKIKSAEENNNEIASKLKEELRKLETDFDEFNKKRDEFLSKEKRRPWNVDSICKEG 379
             + +++I  ++++ +E A  LK+EL K+E +  E ++   E + KEK+ PWNVD+I K G
Sbjct: 62   MDVKERI--SKKDGDEEA--LKKELEKIEAEGKELDRIESEMIKKEKKTPWNVDTISKPG 117

Query: 380  KTKTIINSFDTQEKP---VNEKDVVDRMKAFVEKYDDDIKKYGLFRKVEEMERFLMKNPH 550
              KT+IN      KP   ++E++   RMK FV++ +   ++YG+ RK ++ +RFL ++ H
Sbjct: 118  FEKTVINK-KAGRKPDENLSEEEREQRMKQFVKENEKLCQQYGMLRKYDDSKRFLQEHLH 176

Query: 551  LVCEDTANHLVIWCIDLAVEEKTNLMEHVSHQCIVMQFILELAKSLKRDPRDCIKPFFAK 730
            LV E+TAN+LVIW I+L +EEK  LM HV+HQCI MQ+ILELAK L  DPR C+  FF+K
Sbjct: 177  LVGEETANYLVIWSINLEMEEKHELMAHVAHQCICMQYILELAKQLDVDPRACVSSFFSK 236

Query: 731  FRSQEPEYQTAFTSELDXXXXXXXXXXXXXXXXXMAKIEEEERQKRLGPGGLDPVEVFAN 910
             +   PEY+  F SE++                 +A+ EEEER++RLGPGGLDP +VF +
Sbjct: 237  IQHCHPEYRAQFDSEIEGFKGRIQKRAQEKIQEAIAQAEEEERKERLGPGGLDPADVFES 296

Query: 911  LPKELQECFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEAS 1090
            LP EL+ CFE +++E+LQ+ ++ M    A+ H+++C+DSG+W+PNA   + D+  E ++ 
Sbjct: 297  LPDELKACFESRDVELLQKTIAAMPVDVAKLHMKRCVDSGLWVPNAADLEGDKKEEDDSD 356

Query: 1091 GEYG 1102
               G
Sbjct: 357  DVAG 360
>sp|O02108|CDC37_CAEEL Probable Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein
            kinase-targeting subunit)
          Length = 370

 Score =  238 bits (607), Expect = 3e-62
 Identities = 132/368 (35%), Positives = 207/368 (56%), Gaps = 7/368 (1%)
 Frame = +2

Query: 14   MPIDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLT 193
            MPIDYS+W  IEVSDDEDDTHPNIDTPSLFRWRH+AR+ER  E  ME+  I+K       
Sbjct: 1    MPIDYSKWKDIEVSDDEDDTHPNIDTPSLFRWRHQARLERMAEKKMEQEKIDKEKGTTSK 60

Query: 194  NIQNTRDKIKSAEENNNEIASKLKEELRKLETDFDEFNKKRDEFLSKEKRRPWNVDSICK 373
             ++    K+ +A+  +    S +++++ +++   + + KK  E   KE+  PWNVD+I  
Sbjct: 61   KMEELEKKLAAADVTDK---SDIQKQIDEVKAQEEAWRKKEAELEEKERLEPWNVDTIGH 117

Query: 374  EGKTKTIINSFDTQ--EKPVNEKDVVDRMKAFVEKYDDDIKKYGLFRK-VEEMERFLMKN 544
            E  + + IN    +  + P  +++    M  F E ++  ++K  + +   +  E FL ++
Sbjct: 118  EAFSTSRINKITEKKPQAPKTDEEDTHAMSTFFETHESLLEKMAVLKNGAKSTELFLAEH 177

Query: 545  PHLVCEDTANHLVIWCIDLAVEEKTNLMEHVSHQCIVMQFILELAKSLKRDPRDCI--KP 718
            PH+  E TAN L I  ++ A++     M+ ++ QCI++Q++LEL+KSL     +    K 
Sbjct: 178  PHMASEYTANWLTIEALNAAIDFNEEKMKTMAEQCIIIQYLLELSKSLNAVATNTTVQKQ 237

Query: 719  FFAKFRSQEPEYQTAFTSELDXXXXXXXXXXXXXXXXXMAKIEEEERQKRL--GPGGLDP 892
            FF KF + EP Y   +  E+                  M + E EE+ +R+   PGG+DP
Sbjct: 238  FFKKFEAAEPVYMKHYQDEVKAFEDRLRTRAQTKRDAAMEEAEAEEKAERMKSAPGGIDP 297

Query: 893  VEVFANLPKELQECFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEA 1072
             EVF  LP+E+++CFE  +IE L+    KMD +  + H  +CI SG+W+P   K D+D+ 
Sbjct: 298  QEVFEQLPEEMRKCFEAHDIEALKGVAQKMDEEVFKYHFDRCIASGLWVP--GKADDDDD 355

Query: 1073 NESEASGE 1096
            +E  A  E
Sbjct: 356  DEEAAPAE 363
>sp|Q8X1E6|CDC37_CANAL Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
           subunit) (Cell division control protein 37)
          Length = 508

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 40/113 (35%), Positives = 60/113 (53%), Gaps = 6/113 (5%)
 Frame = +2

Query: 14  MPIDYSRWDHIEVSDDED-DTHPNIDTPSLFRWRHKARVERDQEFNMEKNDI---EKVYK 181
           MPIDYS+WD IE+SDD D + HPN+D  S  RW+ +   E+  + N+E   I     +Y 
Sbjct: 1   MPIDYSKWDKIEISDDSDVEVHPNVDKQSFIRWKQRDIHEKRMQRNIEIKSILIQLTMYA 60

Query: 182 EFLTNIQNTRDKIKSAEENNNE-IASKLKEELRKLET-DFDEFNKKRDEFLSK 334
           +    +    +K+ S E  ++E + SKL  E    E  D+D+  K +   L K
Sbjct: 61  KLNERVDYLLEKLTSTELLDSEKVMSKLNSEFDPQEKFDYDKLIKDKGSTLRK 113

 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 71/355 (20%), Positives = 144/355 (40%), Gaps = 61/355 (17%)
 Frame = +2

Query: 131  RDQEFNMEKNDIEKVYKEFLTNI-QNTRDKIKSAEENNNEIASKLKEELRKLETDFDEFN 307
            +D +F+ E+ +    Y E + ++    +D     + + +++   LKE   +++    +  
Sbjct: 116  KDLKFDREEIENTPCYNEMIEDLFVQIKDDHPETKTDGDKLIEYLKEHRNRIDDVLSKQT 175

Query: 308  KKRDE---------------------FLSKEK--RRPWNVDSICKEGKTKTIINSFDT-- 412
             K D+                     FL+K+K   +  N D        KT + + +T  
Sbjct: 176  IKLDDLLYQKAQLIVSDDLHTGFDRSFLNKDKPEEKEENQDKPKAPEAKKTTVTTTETIN 235

Query: 413  QEKPVNE---KDVVDRM------KAFVEKYDDDIKKYGLFRKVEEMERFLMKNPHLVCED 565
              KPV E   K+++D +      K F +   D++ K            FL+K+P +  E 
Sbjct: 236  SPKPVEENTDKEILDELEILPATKEFAKIPSDNLSKAA---------EFLIKHPSICTEQ 286

Query: 566  TANHLVIWCIDLAVEEKTNLMEHVSHQCIVMQFILELAKSLKRDPR---DCIKPFFAKFR 736
              + L++   DL +E K++  +H+ HQ +++Q++ +L+ + K  P    + IK FF+K  
Sbjct: 287  QKDALIMTAFDLQLENKSDEAKHIVHQSLLLQYVGQLSDNGKAAPANVINAIKLFFSKIA 346

Query: 737  SQEPEYQTAFTSELDXXXXXXXXXXXXXXXXXMAKI-------EEEERQKRLGPGGLD-- 889
            ++    + AF  +++                            EEEE +  +    LD  
Sbjct: 347  AESSPAKHAFLEDVNQTFNHIKGRCEIIKEEQKQNAANKEGTGEEEEEEALIQLKALDDN 406

Query: 890  -------------PVEVF-ANLPKELQECFEKKNIEMLQEALSKMDPKEAEGHLQ 1012
                           E+F   LP E Q   + ++I+ + +  +K+  ++AE  L+
Sbjct: 407  TELSVNIPQEGTKEYEIFTTKLPIEFQNAIKTESIDEVNKEFAKLKIEDAERILE 461
>sp|P06101|CDC37_YEAST Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
           subunit) (Cell division control protein 37)
          Length = 506

 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 47/189 (24%), Positives = 87/189 (46%), Gaps = 5/189 (2%)
 Frame = +2

Query: 14  MPIDYSRWDHIEVSDDED-DTHPNIDTPSLFRWR----HKARVERDQEFNMEKNDIEKVY 178
           M IDYS+WD IE+SDD D + HPN+D  S  +W+    H+ R +R+Q+    +  +    
Sbjct: 1   MAIDYSKWDKIELSDDSDVEVHPNVDKKSFIKWKQQSIHEQRFKRNQDIKNLETQV---- 56

Query: 179 KEFLTNIQNTRDKIKSAEENNNEIASKLKEELRKLETDFDEFNKKRDEFLSKEKRRPWNV 358
            +  +++    D+I S    ++   + L    + L  +FD+  K + E +  E      +
Sbjct: 57  -DMYSHLNKRVDRILSNLPESS--LTDLPAVTKFLNANFDKMEKSKGENVDPEIATYNEM 113

Query: 359 DSICKEGKTKTIINSFDTQEKPVNEKDVVDRMKAFVEKYDDDIKKYGLFRKVEEMERFLM 538
                E   K +       + P   +D + + +A ++    + KK     K++E+  +  
Sbjct: 114 VEDLFEQLAKDLDKEGKDSKSPSLIRDAILKHRAKIDSVTVEAKK-----KLDEL--YKE 166

Query: 539 KNPHLVCED 565
           KN H+  ED
Sbjct: 167 KNAHISSED 175
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 147,394,156
Number of Sequences: 369166
Number of extensions: 2899368
Number of successful extensions: 11407
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 10106
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11324
length of database: 68,354,980
effective HSP length: 114
effective length of database: 47,295,190
effective search space used: 17215449160
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_01081

  1. Dr_sW_027_C02
  2. Dr_sW_005_P11
  3. Dr_sW_008_P06
  4. Dr_sW_022_O03
  5. Dr_sW_011_M11
  6. Dr_sW_005_D16