Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_C02
(320 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q24276|CDC37_DROME Hsp90 co-chaperone Cdc37 (Hsp90 chape... 100 2e-21
sp|Q24740|CDC37_DROVI Hsp90 co-chaperone Cdc37 (Hsp90 chape... 99 2e-21
sp|Q16543|CDC37_HUMAN Hsp90 co-chaperone Cdc37 (Hsp90 chape... 98 5e-21
sp|Q61081|CDC37_MOUSE Hsp90 co-chaperone Cdc37 (Hsp90 chape... 98 7e-21
sp|O57476|CDC37_CHICK Hsp90 co-chaperone Cdc37 (Hsp90 chape... 97 9e-21
sp|Q63692|CDC37_RAT Hsp90 co-chaperone Cdc37 (Hsp90 chapero... 97 1e-20
sp|Q9DGQ7|CDC37_TETFL Hsp90 co-chaperone Cdc37 (Hsp90 chape... 94 7e-20
sp|O02108|CDC37_CAEEL Probable Hsp90 co-chaperone Cdc37 (Hs... 93 2e-19
sp|Q8X1E6|CDC37_CANAL Hsp90 co-chaperone Cdc37 (Hsp90 chape... 63 2e-10
sp|P06101|CDC37_YEAST Hsp90 co-chaperone Cdc37 (Hsp90 chape... 53 2e-07
>sp|Q24276|CDC37_DROME Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit) (Enhancer of sevenless 3B)
Length = 389
Score = 99.8 bits (247), Expect = 2e-21
Identities = 46/97 (47%), Positives = 71/97 (73%)
Frame = +2
Query: 20 IDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLTNI 199
+DYS+W +IE+SDDEDDTHPNIDTPSLFRWRH+ARVER E + EK++++K + + +
Sbjct: 2 VDYSKWKNIEISDDEDDTHPNIDTPSLFRWRHQARVERMAEMDHEKDELKKKRQSYQARL 61
Query: 200 QNTRDKIKSAEENNNEIASKLKEELRKLETDFDEFNK 310
+ +++I S ++ + E LK+EL K+E + E ++
Sbjct: 62 MDVKERI-SKKDGDEE---ALKKELEKIEAEGKELDR 94
>sp|Q24740|CDC37_DROVI Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit)
Length = 399
Score = 99.4 bits (246), Expect = 2e-21
Identities = 47/100 (47%), Positives = 70/100 (70%)
Frame = +2
Query: 20 IDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLTNI 199
+DYS+W +IE+SDDED+THPNIDTPSLFRWRH+ARVER E EK +++K + + +
Sbjct: 2 VDYSKWKNIEISDDEDETHPNIDTPSLFRWRHQARVERMAESEKEKEELKKKRQSYQARL 61
Query: 200 QNTRDKIKSAEENNNEIASKLKEELRKLETDFDEFNKKRD 319
N ++ I E +E+A LK+EL K+E + E +++ +
Sbjct: 62 INVKELISKKE--GDEVA--LKKELEKIENEGKELDRQEN 97
>sp|Q16543|CDC37_HUMAN Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit) (p50Cdc37)
Length = 378
Score = 98.2 bits (243), Expect = 5e-21
Identities = 49/107 (45%), Positives = 66/107 (61%), Gaps = 9/107 (8%)
Frame = +2
Query: 20 IDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLTNI 199
+DYS WDHIEVSDDED+THPNIDT SLFRWRH+ARVER ++F EK ++++ +E +
Sbjct: 2 VDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKV 61
Query: 200 QNTRDKIKSAE---------ENNNEIASKLKEELRKLETDFDEFNKK 313
+ K+K E E A +L++E R E +E KK
Sbjct: 62 AECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKK 108
>sp|Q61081|CDC37_MOUSE Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit) (p50Cdc37)
Length = 379
Score = 97.8 bits (242), Expect = 7e-21
Identities = 48/108 (44%), Positives = 70/108 (64%), Gaps = 10/108 (9%)
Frame = +2
Query: 20 IDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLTNI 199
+DYS WDHIEVSDDED+THPNIDT SLFRWRH+ARVER ++F EK ++++ +E +
Sbjct: 2 VDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKV 61
Query: 200 QNTRDKIKSAE--ENNNEI--------ASKLKEELRKLETDFDEFNKK 313
+ K+K E E++ ++ A +L++E R E ++ KK
Sbjct: 62 AECQRKLKELEVAESDGQVELERLRAEAQQLRKEERSWEQKLEDMRKK 109
>sp|O57476|CDC37_CHICK Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit) (p50Cdc37)
Length = 393
Score = 97.4 bits (241), Expect = 9e-21
Identities = 50/113 (44%), Positives = 66/113 (58%), Gaps = 15/113 (13%)
Frame = +2
Query: 20 IDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLTNI 199
+DYS WDHIEVSDDED+THPNIDT SLFRWRH+ARVER ++F EK +++K +E +
Sbjct: 2 VDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDKGCRECKRKL 61
Query: 200 QNTRDKIKSAE---------------ENNNEIASKLKEELRKLETDFDEFNKK 313
+ K+K E E A +L+ E R E+ +E KK
Sbjct: 62 AECQKKLKELEVAEPGGGSGGGRGERERLQAEAQQLRHEERNWESKMEELRKK 114
>sp|Q63692|CDC37_RAT Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit) (p50Cdc37)
Length = 379
Score = 97.1 bits (240), Expect = 1e-20
Identities = 48/108 (44%), Positives = 68/108 (62%), Gaps = 10/108 (9%)
Frame = +2
Query: 20 IDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLTNI 199
+DYS WDHIEVSDDED+THPNIDT SLFRWRH+ARVER ++F EK ++++ +E +
Sbjct: 2 VDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKV 61
Query: 200 QNTRDKIKSAE--ENNNEI--------ASKLKEELRKLETDFDEFNKK 313
+ K+K E E ++ A +L++E R E ++ KK
Sbjct: 62 AECQRKLKELEVAEGGGQVELERLRAEAQQLRKEERSWEQKLEDMRKK 109
>sp|Q9DGQ7|CDC37_TETFL Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit) (p50Cdc37)
Length = 377
Score = 94.4 bits (233), Expect = 7e-20
Identities = 47/98 (47%), Positives = 64/98 (65%)
Frame = +2
Query: 20 IDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLTNI 199
IDYS WDHIEVSDDED +HPNIDTPSLFRWRH+ARVER ++F + +D+ K +E +
Sbjct: 4 IDYSVWDHIEVSDDEDVSHPNIDTPSLFRWRHQARVERMEDFKKKGDDLNKGLQECRRKL 63
Query: 200 QNTRDKIKSAEENNNEIASKLKEELRKLETDFDEFNKK 313
+ K++ E + A K EL K +T+ + K+
Sbjct: 64 AEAQKKVR---ELSISAAGDAKAELTKTQTEEKKLKKE 98
>sp|O02108|CDC37_CAEEL Probable Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein
kinase-targeting subunit)
Length = 370
Score = 93.2 bits (230), Expect = 2e-19
Identities = 45/91 (49%), Positives = 59/91 (64%)
Frame = +2
Query: 14 MPIDYSRWDHIEVSDDEDDTHPNIDTPSLFRWRHKARVERDQEFNMEKNDIEKVYKEFLT 193
MPIDYS+W IEVSDDEDDTHPNIDTPSLFRWRH+AR+ER E ME+ I+K
Sbjct: 1 MPIDYSKWKDIEVSDDEDDTHPNIDTPSLFRWRHQARLERMAEKKMEQEKIDKEKGTTSK 60
Query: 194 NIQNTRDKIKSAEENNNEIASKLKEELRKLE 286
++ K+ +A+ + K +E++ E
Sbjct: 61 KMEELEKKLAAADVTDKSDIQKQIDEVKAQE 91
>sp|Q8X1E6|CDC37_CANAL Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit) (Cell division control protein 37)
Length = 508
Score = 63.2 bits (152), Expect = 2e-10
Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 6/107 (5%)
Frame = +2
Query: 14 MPIDYSRWDHIEVSDDED-DTHPNIDTPSLFRWRHKARVERDQEFNMEKNDI---EKVYK 181
MPIDYS+WD IE+SDD D + HPN+D S RW+ + E+ + N+E I +Y
Sbjct: 1 MPIDYSKWDKIEISDDSDVEVHPNVDKQSFIRWKQRDIHEKRMQRNIEIKSILIQLTMYA 60
Query: 182 EFLTNIQNTRDKIKSAEENNNE-IASKLKEELRKLET-DFDEFNKKR 316
+ + +K+ S E ++E + SKL E E D+D+ K +
Sbjct: 61 KLNERVDYLLEKLTSTELLDSEKVMSKLNSEFDPQEKFDYDKLIKDK 107
>sp|P06101|CDC37_YEAST Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit) (Cell division control protein 37)
Length = 506
Score = 53.1 bits (126), Expect = 2e-07
Identities = 31/106 (29%), Positives = 55/106 (51%), Gaps = 5/106 (4%)
Frame = +2
Query: 14 MPIDYSRWDHIEVSDDED-DTHPNIDTPSLFRWR----HKARVERDQEFNMEKNDIEKVY 178
M IDYS+WD IE+SDD D + HPN+D S +W+ H+ R +R+Q+ + +
Sbjct: 1 MAIDYSKWDKIELSDDSDVEVHPNVDKKSFIKWKQQSIHEQRFKRNQDIKNLETQV---- 56
Query: 179 KEFLTNIQNTRDKIKSAEENNNEIASKLKEELRKLETDFDEFNKKR 316
+ +++ D+I S ++ + L + L +FD+ K +
Sbjct: 57 -DMYSHLNKRVDRILSNLPESS--LTDLPAVTKFLNANFDKMEKSK 99
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,475,984
Number of Sequences: 369166
Number of extensions: 526429
Number of successful extensions: 3364
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3093
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3349
length of database: 68,354,980
effective HSP length: 75
effective length of database: 54,499,855
effective search space used: 1689495505
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)