Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_005_D16 (511 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9DGQ7|CDC37_TETFL Hsp90 co-chaperone Cdc37 (Hsp90 chape... 70 2e-12 sp|Q61081|CDC37_MOUSE Hsp90 co-chaperone Cdc37 (Hsp90 chape... 70 4e-12 sp|Q63692|CDC37_RAT Hsp90 co-chaperone Cdc37 (Hsp90 chapero... 70 4e-12 sp|Q16543|CDC37_HUMAN Hsp90 co-chaperone Cdc37 (Hsp90 chape... 69 5e-12 sp|O57476|CDC37_CHICK Hsp90 co-chaperone Cdc37 (Hsp90 chape... 68 1e-11 sp|Q24276|CDC37_DROME Hsp90 co-chaperone Cdc37 (Hsp90 chape... 54 2e-07 sp|Q24740|CDC37_DROVI Hsp90 co-chaperone Cdc37 (Hsp90 chape... 54 3e-07 sp|O02108|CDC37_CAEEL Probable Hsp90 co-chaperone Cdc37 (Hs... 47 3e-05 sp|Q9TKS4|MATK_PHACN Maturase K (Intron maturase) 33 0.30 sp|Q6PSC6|MATK_PHAVU Maturase K (Intron maturase) 33 0.51
>sp|Q9DGQ7|CDC37_TETFL Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) Length = 377 Score = 70.5 bits (171), Expect = 2e-12 Identities = 26/57 (45%), Positives = 44/57 (77%) Frame = +1 Query: 1 QECFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEASGE 171 Q+CF++K+I+MLQ+ ++KMDP EA+ H+++CIDSG+W+PN+ ++DE + E Sbjct: 309 QKCFDEKDIQMLQDVITKMDPTEAKAHMKRCIDSGLWVPNSKMDESDEKEDGSTYEE 365
>sp|Q61081|CDC37_MOUSE Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) Length = 379 Score = 69.7 bits (169), Expect = 4e-12 Identities = 29/56 (51%), Positives = 45/56 (80%) Frame = +1 Query: 1 QECFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEASG 168 Q+CF+ K+++MLQ+A+SKMDP +A+ H+Q+CIDSG+W+PN+ + EA E E +G Sbjct: 307 QKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSK---SGEAKEGEEAG 359
>sp|Q63692|CDC37_RAT Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) Length = 379 Score = 69.7 bits (169), Expect = 4e-12 Identities = 29/56 (51%), Positives = 45/56 (80%) Frame = +1 Query: 1 QECFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEASG 168 Q+CF+ K+++MLQ+A+SKMDP +A+ H+Q+CIDSG+W+PN+ + EA E E +G Sbjct: 307 QKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSK---SGEAKEGEEAG 359
>sp|Q16543|CDC37_HUMAN Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) Length = 378 Score = 69.3 bits (168), Expect = 5e-12 Identities = 29/56 (51%), Positives = 44/56 (78%) Frame = +1 Query: 1 QECFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEASG 168 Q+CF+ K+++MLQ+A+SKMDP +A+ H+Q+CIDSG+W+PN+ EA E E +G Sbjct: 306 QKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKA---SEAKEGEEAG 358
>sp|O57476|CDC37_CHICK Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) Length = 393 Score = 67.8 bits (164), Expect = 1e-11 Identities = 29/61 (47%), Positives = 45/61 (73%) Frame = +1 Query: 1 QECFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEASGEYGN 180 Q+CF+ K+++MLQ+ +S+MDP EA+ H+Q+CIDSG+W+PNA K + + A G+ G Sbjct: 311 QKCFDAKDVQMLQDTISRMDPTEAKYHMQRCIDSGLWVPNA-KAAAEGGGQGGAHGQPGG 369 Query: 181 A 183 A Sbjct: 370 A 370
>sp|Q24276|CDC37_DROME Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (Enhancer of sevenless 3B) Length = 389 Score = 54.3 bits (129), Expect = 2e-07 Identities = 20/57 (35%), Positives = 38/57 (66%) Frame = +1 Query: 7 CFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEASGEYG 177 CFE +++E+LQ+ ++ M A+ H+++C+DSG+W+PNA + D+ E ++ G Sbjct: 304 CFESRDVELLQKTIAAMPVDVAKLHMKRCVDSGLWVPNAADLEGDKKEEDDSDDVAG 360
>sp|Q24740|CDC37_DROVI Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) Length = 399 Score = 53.5 bits (127), Expect = 3e-07 Identities = 22/57 (38%), Positives = 38/57 (66%), Gaps = 4/57 (7%) Frame = +1 Query: 7 CFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANK----KDNDEANESEAS 165 CFE ++IE+LQ+ ++ M +A+ H+++C+DSG+W+PNA D EA + E + Sbjct: 304 CFESRDIELLQKTIATMPVDQAKYHMKRCVDSGLWVPNAADVQLGNDETEAKDDETT 360
>sp|O02108|CDC37_CAEEL Probable Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) Length = 370 Score = 47.0 bits (110), Expect = 3e-05 Identities = 22/57 (38%), Positives = 34/57 (59%) Frame = +1 Query: 1 QECFEKKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEASGE 171 ++CFE +IE L+ KMD + + H +CI SG+W+P K D+D+ +E A E Sbjct: 309 RKCFEAHDIEALKGVAQKMDEEVFKYHFDRCIASGLWVP--GKADDDDDDEEAAPAE 363
>sp|Q9TKS4|MATK_PHACN Maturase K (Intron maturase) Length = 514 Score = 33.5 bits (75), Expect = 0.30 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 18/81 (22%) Frame = -1 Query: 400 CAY--FFFQRKFAYYL*IKLLFYQ----LILTNTEILMNE*QLILIINRCAYFHIWNYPQ 239 C+Y FFF+ F +Y+ YQ L+L NT +L+N+ + I YF IW P+ Sbjct: 262 CSYTLFFFKDTFIHYV-----RYQGKSILVLKNTPLLINKWKYYFIYLWQCYFDIWAGPE 316 Query: 238 ------------HFPGYLVSL 212 HF GY +S+ Sbjct: 317 TIYINQLSQYSFHFLGYFLSI 337
>sp|Q6PSC6|MATK_PHAVU Maturase K (Intron maturase) Length = 513 Score = 32.7 bits (73), Expect = 0.51 Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 18/81 (22%) Frame = -1 Query: 400 CAY--FFFQRKFAYYL*IKLLFYQ----LILTNTEILMNE*QLILIINRCAYFHIWNYPQ 239 C+Y FFF+ F +Y+ YQ L+L NT +L+N+ + + YF IW P+ Sbjct: 261 CSYTLFFFKDTFIHYV-----RYQGKSILVLKNTPLLINKWKYYFLYLWQCYFDIWAGPE 315 Query: 238 ------------HFPGYLVSL 212 HF GY +S+ Sbjct: 316 TIYINQLSQYSFHFLGYFLSI 336
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 56,664,322 Number of Sequences: 369166 Number of extensions: 1054746 Number of successful extensions: 2776 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2608 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2776 length of database: 68,354,980 effective HSP length: 103 effective length of database: 49,327,275 effective search space used: 3255600150 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)