Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_M11
(380 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9DGQ7|CDC37_TETFL Hsp90 co-chaperone Cdc37 (Hsp90 chape... 64 1e-10
sp|Q61081|CDC37_MOUSE Hsp90 co-chaperone Cdc37 (Hsp90 chape... 62 5e-10
sp|Q63692|CDC37_RAT Hsp90 co-chaperone Cdc37 (Hsp90 chapero... 62 5e-10
sp|Q16543|CDC37_HUMAN Hsp90 co-chaperone Cdc37 (Hsp90 chape... 61 7e-10
sp|O57476|CDC37_CHICK Hsp90 co-chaperone Cdc37 (Hsp90 chape... 60 2e-09
sp|Q24276|CDC37_DROME Hsp90 co-chaperone Cdc37 (Hsp90 chape... 49 5e-06
sp|Q24740|CDC37_DROVI Hsp90 co-chaperone Cdc37 (Hsp90 chape... 48 8e-06
sp|O02108|CDC37_CAEEL Probable Hsp90 co-chaperone Cdc37 (Hs... 40 0.001
sp|P10074|HKR3_HUMAN Krueppel-related zinc finger protein 3... 32 0.59
sp|P57296|PBPB_BUCAI Penicillin-binding protein 1B (PBP-1b)... 31 0.77
>sp|Q9DGQ7|CDC37_TETFL Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit) (p50Cdc37)
Length = 377
Score = 63.9 bits (154), Expect = 1e-10
Identities = 24/53 (45%), Positives = 40/53 (75%)
Frame = +2
Query: 11 EEKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEASGE 169
+EK+I+MLQ+ ++KMDP EA+ H+++CIDSG+W+PN+ ++DE + E
Sbjct: 313 DEKDIQMLQDVITKMDPTEAKAHMKRCIDSGLWVPNSKMDESDEKEDGSTYEE 365
>sp|Q61081|CDC37_MOUSE Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit) (p50Cdc37)
Length = 379
Score = 61.6 bits (148), Expect = 5e-10
Identities = 26/50 (52%), Positives = 40/50 (80%)
Frame = +2
Query: 17 KNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEASG 166
K+++MLQ+A+SKMDP +A+ H+Q+CIDSG+W+PN+ + EA E E +G
Sbjct: 313 KDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSK---SGEAKEGEEAG 359
>sp|Q63692|CDC37_RAT Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit) (p50Cdc37)
Length = 379
Score = 61.6 bits (148), Expect = 5e-10
Identities = 26/50 (52%), Positives = 40/50 (80%)
Frame = +2
Query: 17 KNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEASG 166
K+++MLQ+A+SKMDP +A+ H+Q+CIDSG+W+PN+ + EA E E +G
Sbjct: 313 KDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSK---SGEAKEGEEAG 359
>sp|Q16543|CDC37_HUMAN Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit) (p50Cdc37)
Length = 378
Score = 61.2 bits (147), Expect = 7e-10
Identities = 26/50 (52%), Positives = 39/50 (78%)
Frame = +2
Query: 17 KNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEASG 166
K+++MLQ+A+SKMDP +A+ H+Q+CIDSG+W+PN+ EA E E +G
Sbjct: 312 KDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKA---SEAKEGEEAG 358
>sp|O57476|CDC37_CHICK Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit) (p50Cdc37)
Length = 393
Score = 59.7 bits (143), Expect = 2e-09
Identities = 26/57 (45%), Positives = 41/57 (71%)
Frame = +2
Query: 11 EEKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEASGEYGNA 181
+ K+++MLQ+ +S+MDP EA+ H+Q+CIDSG+W+PNA K + + A G+ G A
Sbjct: 315 DAKDVQMLQDTISRMDPTEAKYHMQRCIDSGLWVPNA-KAAAEGGGQGGAHGQPGGA 370
>sp|Q24276|CDC37_DROME Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit) (Enhancer of sevenless 3B)
Length = 389
Score = 48.5 bits (114), Expect = 5e-06
Identities = 18/55 (32%), Positives = 36/55 (65%)
Frame = +2
Query: 11 EEKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEASGEYG 175
E +++E+LQ+ ++ M A+ H+++C+DSG+W+PNA + D+ E ++ G
Sbjct: 306 ESRDVELLQKTIAAMPVDVAKLHMKRCVDSGLWVPNAADLEGDKKEEDDSDDVAG 360
>sp|Q24740|CDC37_DROVI Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting
subunit)
Length = 399
Score = 47.8 bits (112), Expect = 8e-06
Identities = 20/55 (36%), Positives = 36/55 (65%), Gaps = 4/55 (7%)
Frame = +2
Query: 11 EEKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANK----KDNDEANESEAS 163
E ++IE+LQ+ ++ M +A+ H+++C+DSG+W+PNA D EA + E +
Sbjct: 306 ESRDIELLQKTIATMPVDQAKYHMKRCVDSGLWVPNAADVQLGNDETEAKDDETT 360
>sp|O02108|CDC37_CAEEL Probable Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein
kinase-targeting subunit)
Length = 370
Score = 40.4 bits (93), Expect = 0.001
Identities = 20/53 (37%), Positives = 30/53 (56%)
Frame = +2
Query: 11 EEKNIEMLQEALSKMDPKEAEGHLQKCIDSGMWLPNANKKDNDEANESEASGE 169
E +IE L+ KMD + + H +CI SG+W+P K D+D+ +E A E
Sbjct: 313 EAHDIEALKGVAQKMDEEVFKYHFDRCIASGLWVP--GKADDDDDDEEAAPAE 363
>sp|P10074|HKR3_HUMAN Krueppel-related zinc finger protein 3 (HKR3 protein)
Length = 688
Score = 31.6 bits (70), Expect = 0.59
Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
Frame = +3
Query: 27 KCYKKLYQKWIQKRQKAICRNVSIVECGYRMRIRRTMMKQMN-QRRAENMEMQTRKMRNL 203
K +K + Q + R+ R ECGY+ + + + M R EN + RK+RNL
Sbjct: 557 KTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNL 616
>sp|P57296|PBPB_BUCAI Penicillin-binding protein 1B (PBP-1b) (PBP1b) (Murein polymerase)
[Includes: Penicillin-insensitive transglycosylase
(Peptidoglycan glycosyltransferase) (Peptidoglycan
TGase); Penicillin-sensitive transpeptidase
(DD-transpeptidase)]
Length = 760
Score = 31.2 bits (69), Expect = 0.77
Identities = 23/73 (31%), Positives = 35/73 (47%)
Frame = -1
Query: 371 FAYYL*IKLLFYQLILTNTEILMNE*QLILIINRCAYFHIWNYPQHFPGYLVSLCS*IPH 192
F Y IK+ F+ LILT L L + INR +WN+P G +V+L +
Sbjct: 5 FKKYFLIKVFFFVLILT----LCYGLYLYVKINRFINGKVWNFPTSIYGRIVNLEPGNSY 60
Query: 191 LPRLHFHILRSPL 153
+ H+L+S +
Sbjct: 61 SQKEVLHLLKSTM 73
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,890,768
Number of Sequences: 369166
Number of extensions: 728871
Number of successful extensions: 2342
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2283
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2342
length of database: 68,354,980
effective HSP length: 93
effective length of database: 51,174,625
effective search space used: 1688762625
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)