Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01055 (1123 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich... 174 5e-43 sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (E... 173 9e-43 sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich... 168 2e-41 sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4 168 2e-41 sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5... 161 3e-39 sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich... 161 3e-39 sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich... 145 2e-34 sp|Q23121|RSP1_CAEEL Probable splicing factor, arginine/ser... 142 1e-33 sp|Q23120|RSP2_CAEEL Probable splicing factor, arginine/ser... 135 3e-31 sp|P78814|SRP2_SCHPO Pre-mRNA splicing factor srp2 125 2e-28
>sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich 6 (Pre-mRNA splicing factor SRP55) Length = 344 Score = 174 bits (440), Expect = 5e-43 Identities = 90/189 (47%), Positives = 118/189 (62%) Frame = +3 Query: 3 PRLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLL 182 PR+YIG L + E+DI++FF YGR+ VDLKNGYGFVE +D RDA+DA+++L+G +L Sbjct: 2 PRVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKELC 61 Query: 183 GERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRI 362 GERV VE AR P+R+E+R+ Sbjct: 62 GERVIVEHARG---------PRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRL 112 Query: 363 IVDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELY 542 IV+ LSSR SWQDLKD MR+ GEVT+ADAHK R N+GV+EF + SDMK A+DK DG E+ Sbjct: 113 IVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEIN 172 Query: 543 GYNLKVHED 569 G N+++ ED Sbjct: 173 GRNIRLIED 181
>sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (Enhancer of deformed) (52-kDa bracketing protein) (B52 protein) Length = 376 Score = 173 bits (438), Expect = 9e-43 Identities = 90/188 (47%), Positives = 120/188 (63%) Frame = +3 Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185 R+Y+G LP + ERD+++FF+ YGR R + +KNGYGFVE +D RDA+DA+++L+G +LLG Sbjct: 5 RVYVGGLPYGVRERDLERFFKGYGRTRDILIKNGYGFVEFEDYRDADDAVYELNGKELLG 64 Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365 ERV VE AR A P+R+E+R+I Sbjct: 65 ERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGP-PLRTEYRLI 123 Query: 366 VDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYG 545 V+ LSSRVSWQDLKD MR+ GEVT+ADAHK R+N+GVVEF++ SDMK AI+K D EL G Sbjct: 124 VENLSSRVSWQDLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNG 183 Query: 546 YNLKVHED 569 + + ED Sbjct: 184 RRIHLVED 191
>sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich 4 (Pre-mRNA splicing factor SRP75) (SRP001LB) Length = 494 Score = 168 bits (426), Expect = 2e-41 Identities = 89/189 (47%), Positives = 117/189 (61%) Frame = +3 Query: 3 PRLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLL 182 PR+YIG L + ERD+++FF+ YG+I VDLKNGYGFVE DD RDA+DA+++L+G L Sbjct: 2 PRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLC 61 Query: 183 GERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRI 362 GERV VE AR P R+E+R+ Sbjct: 62 GERVIVEHARG---------------PRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRL 106 Query: 363 IVDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELY 542 IV+ LSSR SWQDLKD MR+ GEVT+ADAHK R+N+GV+EF + SDMK A++K DG E+ Sbjct: 107 IVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVN 166 Query: 543 GYNLKVHED 569 G +++ ED Sbjct: 167 GRKIRLVED 175
>sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4 Length = 489 Score = 168 bits (426), Expect = 2e-41 Identities = 89/189 (47%), Positives = 117/189 (61%) Frame = +3 Query: 3 PRLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLL 182 PR+YIG L + ERD+++FF+ YG+I VDLKNGYGFVE DD RDA+DA+++L+G L Sbjct: 2 PRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLC 61 Query: 183 GERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRI 362 GERV VE AR P R+E+R+ Sbjct: 62 GERVIVEHARG---------------PRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRL 106 Query: 363 IVDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELY 542 IV+ LSSR SWQDLKD MR+ GEVT+ADAHK R+N+GV+EF + SDMK A++K DG E+ Sbjct: 107 IVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVN 166 Query: 543 GYNLKVHED 569 G +++ ED Sbjct: 167 GRKIRLVED 175
>sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor SRP40) (Insulin-induced growth response protein CL-4) (Delayed-early protein HRS) Length = 269 Score = 161 bits (408), Expect = 3e-39 Identities = 83/187 (44%), Positives = 117/187 (62%) Frame = +3 Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185 R++IG L E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64 Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365 ERVT+E AR+ + P+R+E+R+I Sbjct: 65 ERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAP-------------PVRTENRLI 111 Query: 366 VDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYG 545 V+ LSSRVSWQDLKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K G E+ G Sbjct: 112 VENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEING 171 Query: 546 YNLKVHE 566 +K+ E Sbjct: 172 RKIKLIE 178
>sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor SRP40) (Delayed-early protein HRS) Length = 272 Score = 161 bits (408), Expect = 3e-39 Identities = 83/187 (44%), Positives = 117/187 (62%) Frame = +3 Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185 R++IG L E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64 Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365 ERVT+E AR+ + P+R+E+R+I Sbjct: 65 ERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAP-------------PVRTENRLI 111 Query: 366 VDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYG 545 V+ LSSRVSWQDLKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K G E+ G Sbjct: 112 VENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEING 171 Query: 546 YNLKVHE 566 +K+ E Sbjct: 172 RKIKLIE 178
>sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor SRP40) (Delayed-early protein HRS) Length = 270 Score = 145 bits (367), Expect = 2e-34 Identities = 75/172 (43%), Positives = 106/172 (61%) Frame = +3 Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185 R++IG L E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64 Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365 ERVT+E AR+ + ++ +R+I Sbjct: 65 ERVTIEHARARS-------------RGGRGRGRYSDRLAVADLGNDRRKCSTCKNRNRLI 111 Query: 366 VDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDK 521 V+ LSSRVSWQDLKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K Sbjct: 112 VENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEK 163
>sp|Q23121|RSP1_CAEEL Probable splicing factor, arginine/serine-rich 1 (RNA-binding protein srp-5) (CeSRp75) Length = 312 Score = 142 bits (359), Expect = 1e-33 Identities = 80/198 (40%), Positives = 113/198 (57%), Gaps = 10/198 (5%) Frame = +3 Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185 R+YIG L R+ E+DI+ FFR YG+IR V LKNG+GFVE DD+RDAEDA+HDL+G +L G Sbjct: 4 RIYIGRLTSRVSEKDIEHFFRGYGQIRDVLLKNGFGFVEFDDKRDAEDAVHDLNGKELGG 63 Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIR------ 347 ERV ++ ++ P R Sbjct: 64 ERVILDYSKPRGGGGDRGGFGGGGRGGARVSSYSGGGGGGRDRFDRYDRGPPRRESRYGR 123 Query: 348 ---SEHRIIVDGLSSRVSWQDLKDLMRKVG-EVTFADAHKLRQNQGVVEFSNSSDMKAAI 515 + HR++V+ LSSR+SWQDLKD +R+ G E T+A+AHK R N+ ++ F+ SD+K I Sbjct: 124 PYSTRHRVVVENLSSRISWQDLKDQVRRQGVEPTYAEAHK-RPNEALLCFATPSDLKRCI 182 Query: 516 DKYDGYELYGYNLKVHED 569 +K DG +L G +K+ +D Sbjct: 183 EKCDGMDLNGRKIKMIDD 200
>sp|Q23120|RSP2_CAEEL Probable splicing factor, arginine/serine-rich 2 (RNA-binding protein srp-4) (CeSRp40) Length = 281 Score = 135 bits (339), Expect = 3e-31 Identities = 70/189 (37%), Positives = 107/189 (56%), Gaps = 1/189 (0%) Frame = +3 Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185 R+YIG LP R +RD++ FFR YG++ V +KNG+GFV+ D+RDA+DA+HDL+G +L G Sbjct: 3 RVYIGRLPNRASDRDVEHFFRGYGKLSDVIMKNGFGFVDFQDQRDADDAVHDLNGKELCG 62 Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365 ERV +E R +P + R++ Sbjct: 63 ERVILEFPRRKV-------GYNEERSGSGFRGREPTFRKGGERQFSNRYSRPCSTRFRLV 115 Query: 366 VDGLSSRVSWQDLKDLMRKVG-EVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELY 542 +D LS+R SWQD+KD +RK+G E T+++AHK NQ +V F++ D++ A++K G +L Sbjct: 116 IDNLSTRYSWQDIKDHIRKLGIEPTYSEAHKRNVNQAIVCFTSHDDLRDAMNKLQGEDLN 175 Query: 543 GYNLKVHED 569 G LK ++ Sbjct: 176 GRKLKCTDE 184
>sp|P78814|SRP2_SCHPO Pre-mRNA splicing factor srp2 Length = 365 Score = 125 bits (315), Expect = 2e-28 Identities = 68/188 (36%), Positives = 95/188 (50%) Frame = +3 Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185 RL++G +P + D+ FF+ YG+I L NG+GFVE++D RDA D ++D G + +G Sbjct: 5 RLFVGRIPPQATREDMMDFFKGYGQILDCKLMNGFGFVEVEDARDARDIVNDFQGKEFMG 64 Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365 R+ VE AR +P R+ R+I Sbjct: 65 SRIVVEPARGERRRRENFRESAASKYP-----------------------RPRRTGFRLI 101 Query: 366 VDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYG 545 V+ LS VSWQDLKD+MRK GE TF DAH+ GVVEFS DM+ A+ +G + G Sbjct: 102 VENLSEDVSWQDLKDVMRKAGEPTFTDAHRENPGAGVVEFSTEEDMRNALTSLNGEVIKG 161 Query: 546 YNLKVHED 569 + + ED Sbjct: 162 QAVTLRED 169
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 92,712,491 Number of Sequences: 369166 Number of extensions: 1560547 Number of successful extensions: 4824 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4363 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4737 length of database: 68,354,980 effective HSP length: 112 effective length of database: 47,664,660 effective search space used: 12440476260 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)