Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_D07
(593 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (E... 163 3e-40
sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich... 162 8e-40
sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich... 156 3e-38
sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4 156 3e-38
sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5... 155 9e-38
sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich... 155 9e-38
sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich... 139 5e-33
sp|Q23121|RSP1_CAEEL Probable splicing factor, arginine/ser... 132 5e-31
sp|Q23120|RSP2_CAEEL Probable splicing factor, arginine/ser... 124 1e-28
sp|P78814|SRP2_SCHPO Pre-mRNA splicing factor srp2 117 3e-26
>sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (Enhancer of deformed) (52-kDa
bracketing protein) (B52 protein)
Length = 376
Score = 163 bits (412), Expect = 3e-40
Identities = 86/181 (47%), Positives = 114/181 (62%)
Frame = +3
Query: 3 PRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVEM 182
P + ERD+++FF+ YGR R + +KNGYGFVE +D RDA+DA+++L+G +LLGERV VE
Sbjct: 12 PYGVRERDLERFFKGYGRTRDILIKNGYGFVEFEDYRDADDAVYELNGKELLGERVVVEP 71
Query: 183 ARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSSR 362
AR A P+R+E+R+IV+ LSSR
Sbjct: 72 ARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGP-PLRTEYRLIVENLSSR 130
Query: 363 VSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHE 542
VSWQDLKD MR+ GEVT+ADAHK R+N+GVVEF++ SDMK AI+K D EL G + + E
Sbjct: 131 VSWQDLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLVE 190
Query: 543 D 545
D
Sbjct: 191 D 191
>sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich 6 (Pre-mRNA splicing factor
SRP55)
Length = 344
Score = 162 bits (409), Expect = 8e-40
Identities = 84/178 (47%), Positives = 111/178 (62%)
Frame = +3
Query: 12 IEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVEMARS 191
+ E+DI++FF YGR+ VDLKNGYGFVE +D RDA+DA+++L+G +L GERV VE AR
Sbjct: 13 VREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKELCGERVIVEHARG 72
Query: 192 NAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSSRVSW 371
P+R+E+R+IV+ LSSR SW
Sbjct: 73 ---------PRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSW 123
Query: 372 QDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 545
QDLKD MR+ GEVT+ADAHK R N+GV+EF + SDMK A+DK DG E+ G N+++ ED
Sbjct: 124 QDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIED 181
>sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich 4 (Pre-mRNA splicing factor
SRP75) (SRP001LB)
Length = 494
Score = 156 bits (395), Expect = 3e-38
Identities = 83/176 (47%), Positives = 109/176 (61%)
Frame = +3
Query: 18 ERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVEMARSNA 197
ERD+++FF+ YG+I VDLKNGYGFVE DD RDA+DA+++L+G L GERV VE AR
Sbjct: 15 ERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARG-- 72
Query: 198 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSSRVSWQD 377
P R+E+R+IV+ LSSR SWQD
Sbjct: 73 -------------PRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQD 119
Query: 378 LKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 545
LKD MR+ GEVT+ADAHK R+N+GV+EF + SDMK A++K DG E+ G +++ ED
Sbjct: 120 LKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED 175
>sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4
Length = 489
Score = 156 bits (395), Expect = 3e-38
Identities = 83/176 (47%), Positives = 109/176 (61%)
Frame = +3
Query: 18 ERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVEMARSNA 197
ERD+++FF+ YG+I VDLKNGYGFVE DD RDA+DA+++L+G L GERV VE AR
Sbjct: 15 ERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARG-- 72
Query: 198 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSSRVSWQD 377
P R+E+R+IV+ LSSR SWQD
Sbjct: 73 -------------PRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQD 119
Query: 378 LKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 545
LKD MR+ GEVT+ADAHK R+N+GV+EF + SDMK A++K DG E+ G +++ ED
Sbjct: 120 LKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED 175
>sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor
SRP40) (Insulin-induced growth response protein CL-4)
(Delayed-early protein HRS)
Length = 269
Score = 155 bits (391), Expect = 9e-38
Identities = 79/175 (45%), Positives = 111/175 (63%)
Frame = +3
Query: 18 ERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVEMARSNA 197
E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L ERVT+E AR+ +
Sbjct: 17 EKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARS 76
Query: 198 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSSRVSWQD 377
P+R+E+R+IV+ LSSRVSWQD
Sbjct: 77 RGGRGRGRYSDRFSSRRPRNDRRNAP-------------PVRTENRLIVENLSSRVSWQD 123
Query: 378 LKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHE 542
LKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K G E+ G +K+ E
Sbjct: 124 LKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE 178
>sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor
SRP40) (Delayed-early protein HRS)
Length = 272
Score = 155 bits (391), Expect = 9e-38
Identities = 79/175 (45%), Positives = 111/175 (63%)
Frame = +3
Query: 18 ERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVEMARSNA 197
E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L ERVT+E AR+ +
Sbjct: 17 EKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARS 76
Query: 198 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSSRVSWQD 377
P+R+E+R+IV+ LSSRVSWQD
Sbjct: 77 RGGRGRGRYSDRFSSRRPRNDRRNAP-------------PVRTENRLIVENLSSRVSWQD 123
Query: 378 LKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHE 542
LKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K G E+ G +K+ E
Sbjct: 124 LKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE 178
>sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor
SRP40) (Delayed-early protein HRS)
Length = 270
Score = 139 bits (350), Expect = 5e-33
Identities = 71/160 (44%), Positives = 100/160 (62%)
Frame = +3
Query: 18 ERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVEMARSNA 197
E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L ERVT+E AR+ +
Sbjct: 17 EKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARS 76
Query: 198 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSSRVSWQD 377
++ +R+IV+ LSSRVSWQD
Sbjct: 77 -------------RGGRGRGRYSDRLAVADLGNDRRKCSTCKNRNRLIVENLSSRVSWQD 123
Query: 378 LKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDK 497
LKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K
Sbjct: 124 LKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEK 163
>sp|Q23121|RSP1_CAEEL Probable splicing factor, arginine/serine-rich 1 (RNA-binding
protein srp-5) (CeSRp75)
Length = 312
Score = 132 bits (333), Expect = 5e-31
Identities = 75/189 (39%), Positives = 107/189 (56%), Gaps = 10/189 (5%)
Frame = +3
Query: 9 RIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVEMAR 188
R+ E+DI+ FFR YG+IR V LKNG+GFVE DD+RDAEDA+HDL+G +L GERV ++ ++
Sbjct: 13 RVSEKDIEHFFRGYGQIRDVLLKNGFGFVEFDDKRDAEDAVHDLNGKELGGERVILDYSK 72
Query: 189 SNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIR---------SEHRII 341
P R + HR++
Sbjct: 73 PRGGGGDRGGFGGGGRGGARVSSYSGGGGGGRDRFDRYDRGPPRRESRYGRPYSTRHRVV 132
Query: 342 VDGLSSRVSWQDLKDLMRKVG-EVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELY 518
V+ LSSR+SWQDLKD +R+ G E T+A+AHK R N+ ++ F+ SD+K I+K DG +L
Sbjct: 133 VENLSSRISWQDLKDQVRRQGVEPTYAEAHK-RPNEALLCFATPSDLKRCIEKCDGMDLN 191
Query: 519 GYNLKVHED 545
G +K+ +D
Sbjct: 192 GRKIKMIDD 200
>sp|Q23120|RSP2_CAEEL Probable splicing factor, arginine/serine-rich 2 (RNA-binding
protein srp-4) (CeSRp40)
Length = 281
Score = 124 bits (312), Expect = 1e-28
Identities = 65/182 (35%), Positives = 101/182 (55%), Gaps = 1/182 (0%)
Frame = +3
Query: 3 PRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVEM 182
P R +RD++ FFR YG++ V +KNG+GFV+ D+RDA+DA+HDL+G +L GERV +E
Sbjct: 10 PNRASDRDVEHFFRGYGKLSDVIMKNGFGFVDFQDQRDADDAVHDLNGKELCGERVILEF 69
Query: 183 ARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSSR 362
R +P + R+++D LS+R
Sbjct: 70 PRRKV-------GYNEERSGSGFRGREPTFRKGGERQFSNRYSRPCSTRFRLVIDNLSTR 122
Query: 363 VSWQDLKDLMRKVG-EVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVH 539
SWQD+KD +RK+G E T+++AHK NQ +V F++ D++ A++K G +L G LK
Sbjct: 123 YSWQDIKDHIRKLGIEPTYSEAHKRNVNQAIVCFTSHDDLRDAMNKLQGEDLNGRKLKCT 182
Query: 540 ED 545
++
Sbjct: 183 DE 184
>sp|P78814|SRP2_SCHPO Pre-mRNA splicing factor srp2
Length = 365
Score = 117 bits (292), Expect = 3e-26
Identities = 65/181 (35%), Positives = 89/181 (49%)
Frame = +3
Query: 3 PRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVEM 182
P + D+ FF+ YG+I L NG+GFVE++D RDA D ++D G + +G R+ VE
Sbjct: 12 PPQATREDMMDFFKGYGQILDCKLMNGFGFVEVEDARDARDIVNDFQGKEFMGSRIVVEP 71
Query: 183 ARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSSR 362
AR +P R+ R+IV+ LS
Sbjct: 72 ARGERRRRENFRESAASKYP-----------------------RPRRTGFRLIVENLSED 108
Query: 363 VSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHE 542
VSWQDLKD+MRK GE TF DAH+ GVVEFS DM+ A+ +G + G + + E
Sbjct: 109 VSWQDLKDVMRKAGEPTFTDAHRENPGAGVVEFSTEEDMRNALTSLNGEVIKGQAVTLRE 168
Query: 543 D 545
D
Sbjct: 169 D 169
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,237,702
Number of Sequences: 369166
Number of extensions: 978264
Number of successful extensions: 2927
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2709
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2900
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4504118060
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)