Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_N05
(764 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (E... 164 2e-40
sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich... 162 9e-40
sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich... 157 4e-38
sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4 157 4e-38
sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5... 155 1e-37
sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich... 155 1e-37
sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich... 139 8e-33
sp|Q23121|RSP1_CAEEL Probable splicing factor, arginine/ser... 133 5e-31
sp|Q23120|RSP2_CAEEL Probable splicing factor, arginine/ser... 126 7e-29
sp|P78814|SRP2_SCHPO Pre-mRNA splicing factor srp2 117 3e-26
>sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (Enhancer of deformed) (52-kDa
bracketing protein) (B52 protein)
Length = 376
Score = 164 bits (416), Expect = 2e-40
Identities = 87/182 (47%), Positives = 115/182 (63%)
Frame = +2
Query: 20 LPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVE 199
LP + ERD+++FF+ YGR R + +KNGYGFVE +D RDA+DA+++L+G +LLGERV VE
Sbjct: 11 LPYGVRERDLERFFKGYGRTRDILIKNGYGFVEFEDYRDADDAVYELNGKELLGERVVVE 70
Query: 200 MARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSS 379
AR A P+R+E+R+IV+ LSS
Sbjct: 71 PARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGP-PLRTEYRLIVENLSS 129
Query: 380 RVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVH 559
RVSWQDLKD MR+ GEVT+ADAHK R+N+GVVEF++ SDMK AI+K D EL G + +
Sbjct: 130 RVSWQDLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLV 189
Query: 560 ED 565
ED
Sbjct: 190 ED 191
>sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich 6 (Pre-mRNA splicing factor
SRP55)
Length = 344
Score = 162 bits (410), Expect = 9e-40
Identities = 85/182 (46%), Positives = 112/182 (61%)
Frame = +2
Query: 20 LPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVE 199
L + E+DI++FF YGR+ VDLKNGYGFVE +D RDA+DA+++L+G +L GERV VE
Sbjct: 9 LSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKELCGERVIVE 68
Query: 200 MARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSS 379
AR P+R+E+R+IV+ LSS
Sbjct: 69 HARG---------PRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSS 119
Query: 380 RVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVH 559
R SWQDLKD MR+ GEVT+ADAHK R N+GV+EF + SDMK A+DK DG E+ G N+++
Sbjct: 120 RCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLI 179
Query: 560 ED 565
ED
Sbjct: 180 ED 181
>sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich 4 (Pre-mRNA splicing factor
SRP75) (SRP001LB)
Length = 494
Score = 157 bits (396), Expect = 4e-38
Identities = 84/182 (46%), Positives = 111/182 (60%)
Frame = +2
Query: 20 LPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVE 199
L + ERD+++FF+ YG+I VDLKNGYGFVE DD RDA+DA+++L+G L GERV VE
Sbjct: 9 LSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVE 68
Query: 200 MARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSS 379
AR P R+E+R+IV+ LSS
Sbjct: 69 HARG---------------PRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSS 113
Query: 380 RVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVH 559
R SWQDLKD MR+ GEVT+ADAHK R+N+GV+EF + SDMK A++K DG E+ G +++
Sbjct: 114 RCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLV 173
Query: 560 ED 565
ED
Sbjct: 174 ED 175
>sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4
Length = 489
Score = 157 bits (396), Expect = 4e-38
Identities = 84/182 (46%), Positives = 111/182 (60%)
Frame = +2
Query: 20 LPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVE 199
L + ERD+++FF+ YG+I VDLKNGYGFVE DD RDA+DA+++L+G L GERV VE
Sbjct: 9 LSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVE 68
Query: 200 MARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSS 379
AR P R+E+R+IV+ LSS
Sbjct: 69 HARG---------------PRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSS 113
Query: 380 RVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVH 559
R SWQDLKD MR+ GEVT+ADAHK R+N+GV+EF + SDMK A++K DG E+ G +++
Sbjct: 114 RCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLV 173
Query: 560 ED 565
ED
Sbjct: 174 ED 175
>sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor
SRP40) (Insulin-induced growth response protein CL-4)
(Delayed-early protein HRS)
Length = 269
Score = 155 bits (391), Expect = 1e-37
Identities = 79/175 (45%), Positives = 111/175 (63%)
Frame = +2
Query: 38 ERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVEMARSNA 217
E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L ERVT+E AR+ +
Sbjct: 17 EKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARS 76
Query: 218 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSSRVSWQD 397
P+R+E+R+IV+ LSSRVSWQD
Sbjct: 77 RGGRGRGRYSDRFSSRRPRNDRRNAP-------------PVRTENRLIVENLSSRVSWQD 123
Query: 398 LKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHE 562
LKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K G E+ G +K+ E
Sbjct: 124 LKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE 178
>sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor
SRP40) (Delayed-early protein HRS)
Length = 272
Score = 155 bits (391), Expect = 1e-37
Identities = 79/175 (45%), Positives = 111/175 (63%)
Frame = +2
Query: 38 ERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVEMARSNA 217
E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L ERVT+E AR+ +
Sbjct: 17 EKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARS 76
Query: 218 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSSRVSWQD 397
P+R+E+R+IV+ LSSRVSWQD
Sbjct: 77 RGGRGRGRYSDRFSSRRPRNDRRNAP-------------PVRTENRLIVENLSSRVSWQD 123
Query: 398 LKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHE 562
LKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K G E+ G +K+ E
Sbjct: 124 LKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE 178
>sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor
SRP40) (Delayed-early protein HRS)
Length = 270
Score = 139 bits (350), Expect = 8e-33
Identities = 71/160 (44%), Positives = 100/160 (62%)
Frame = +2
Query: 38 ERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVEMARSNA 217
E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L ERVT+E AR+ +
Sbjct: 17 EKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARS 76
Query: 218 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSSRVSWQD 397
++ +R+IV+ LSSRVSWQD
Sbjct: 77 -------------RGGRGRGRYSDRLAVADLGNDRRKCSTCKNRNRLIVENLSSRVSWQD 123
Query: 398 LKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDK 517
LKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K
Sbjct: 124 LKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEK 163
>sp|Q23121|RSP1_CAEEL Probable splicing factor, arginine/serine-rich 1 (RNA-binding
protein srp-5) (CeSRp75)
Length = 312
Score = 133 bits (335), Expect = 5e-31
Identities = 76/192 (39%), Positives = 108/192 (56%), Gaps = 10/192 (5%)
Frame = +2
Query: 20 LPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVE 199
L R+ E+DI+ FFR YG+IR V LKNG+GFVE DD+RDAEDA+HDL+G +L GERV ++
Sbjct: 10 LTSRVSEKDIEHFFRGYGQIRDVLLKNGFGFVEFDDKRDAEDAVHDLNGKELGGERVILD 69
Query: 200 MARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIR---------SEH 352
++ P R + H
Sbjct: 70 YSKPRGGGGDRGGFGGGGRGGARVSSYSGGGGGGRDRFDRYDRGPPRRESRYGRPYSTRH 129
Query: 353 RIIVDGLSSRVSWQDLKDLMRKVG-EVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGY 529
R++V+ LSSR+SWQDLKD +R+ G E T+A+AHK R N+ ++ F+ SD+K I+K DG
Sbjct: 130 RVVVENLSSRISWQDLKDQVRRQGVEPTYAEAHK-RPNEALLCFATPSDLKRCIEKCDGM 188
Query: 530 ELYGYNLKVHED 565
+L G +K+ +D
Sbjct: 189 DLNGRKIKMIDD 200
>sp|Q23120|RSP2_CAEEL Probable splicing factor, arginine/serine-rich 2 (RNA-binding
protein srp-4) (CeSRp40)
Length = 281
Score = 126 bits (316), Expect = 7e-29
Identities = 66/183 (36%), Positives = 102/183 (55%), Gaps = 1/183 (0%)
Frame = +2
Query: 20 LPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVE 199
LP R +RD++ FFR YG++ V +KNG+GFV+ D+RDA+DA+HDL+G +L GERV +E
Sbjct: 9 LPNRASDRDVEHFFRGYGKLSDVIMKNGFGFVDFQDQRDADDAVHDLNGKELCGERVILE 68
Query: 200 MARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSS 379
R +P + R+++D LS+
Sbjct: 69 FPRRKV-------GYNEERSGSGFRGREPTFRKGGERQFSNRYSRPCSTRFRLVIDNLST 121
Query: 380 RVSWQDLKDLMRKVG-EVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKV 556
R SWQD+KD +RK+G E T+++AHK NQ +V F++ D++ A++K G +L G LK
Sbjct: 122 RYSWQDIKDHIRKLGIEPTYSEAHKRNVNQAIVCFTSHDDLRDAMNKLQGEDLNGRKLKC 181
Query: 557 HED 565
++
Sbjct: 182 TDE 184
>sp|P78814|SRP2_SCHPO Pre-mRNA splicing factor srp2
Length = 365
Score = 117 bits (294), Expect = 3e-26
Identities = 65/182 (35%), Positives = 90/182 (49%)
Frame = +2
Query: 20 LPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLGERVTVE 199
+P + D+ FF+ YG+I L NG+GFVE++D RDA D ++D G + +G R+ VE
Sbjct: 11 IPPQATREDMMDFFKGYGQILDCKLMNGFGFVEVEDARDARDIVNDFQGKEFMGSRIVVE 70
Query: 200 MARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRIIVDGLSS 379
AR +P R+ R+IV+ LS
Sbjct: 71 PARGERRRRENFRESAASKYP-----------------------RPRRTGFRLIVENLSE 107
Query: 380 RVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVH 559
VSWQDLKD+MRK GE TF DAH+ GVVEFS DM+ A+ +G + G + +
Sbjct: 108 DVSWQDLKDVMRKAGEPTFTDAHRENPGAGVVEFSTEEDMRNALTSLNGEVIKGQAVTLR 167
Query: 560 ED 565
ED
Sbjct: 168 ED 169
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,328,758
Number of Sequences: 369166
Number of extensions: 1200536
Number of successful extensions: 3568
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3285
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3527
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7066925600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)