Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_J20
(843 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich... 174 4e-43
sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (E... 173 6e-43
sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich... 168 2e-41
sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4 168 2e-41
sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5... 161 2e-39
sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich... 161 2e-39
sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich... 145 1e-34
sp|Q23121|RSP1_CAEEL Probable splicing factor, arginine/ser... 142 9e-34
sp|Q23120|RSP2_CAEEL Probable splicing factor, arginine/ser... 135 2e-31
sp|P78814|SRP2_SCHPO Pre-mRNA splicing factor srp2 125 1e-28
>sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich 6 (Pre-mRNA splicing factor
SRP55)
Length = 344
Score = 174 bits (440), Expect = 4e-43
Identities = 90/189 (47%), Positives = 118/189 (62%)
Frame = +3
Query: 3 PRLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLL 182
PR+YIG L + E+DI++FF YGR+ VDLKNGYGFVE +D RDA+DA+++L+G +L
Sbjct: 2 PRVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKELC 61
Query: 183 GERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRI 362
GERV VE AR P+R+E+R+
Sbjct: 62 GERVIVEHARG---------PRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRL 112
Query: 363 IVDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELY 542
IV+ LSSR SWQDLKD MR+ GEVT+ADAHK R N+GV+EF + SDMK A+DK DG E+
Sbjct: 113 IVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEIN 172
Query: 543 GYNLKVHED 569
G N+++ ED
Sbjct: 173 GRNIRLIED 181
>sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (Enhancer of deformed) (52-kDa
bracketing protein) (B52 protein)
Length = 376
Score = 173 bits (438), Expect = 6e-43
Identities = 90/188 (47%), Positives = 120/188 (63%)
Frame = +3
Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185
R+Y+G LP + ERD+++FF+ YGR R + +KNGYGFVE +D RDA+DA+++L+G +LLG
Sbjct: 5 RVYVGGLPYGVRERDLERFFKGYGRTRDILIKNGYGFVEFEDYRDADDAVYELNGKELLG 64
Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365
ERV VE AR A P+R+E+R+I
Sbjct: 65 ERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGP-PLRTEYRLI 123
Query: 366 VDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYG 545
V+ LSSRVSWQDLKD MR+ GEVT+ADAHK R+N+GVVEF++ SDMK AI+K D EL G
Sbjct: 124 VENLSSRVSWQDLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNG 183
Query: 546 YNLKVHED 569
+ + ED
Sbjct: 184 RRIHLVED 191
>sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich 4 (Pre-mRNA splicing factor
SRP75) (SRP001LB)
Length = 494
Score = 168 bits (426), Expect = 2e-41
Identities = 89/189 (47%), Positives = 117/189 (61%)
Frame = +3
Query: 3 PRLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLL 182
PR+YIG L + ERD+++FF+ YG+I VDLKNGYGFVE DD RDA+DA+++L+G L
Sbjct: 2 PRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLC 61
Query: 183 GERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRI 362
GERV VE AR P R+E+R+
Sbjct: 62 GERVIVEHARG---------------PRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRL 106
Query: 363 IVDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELY 542
IV+ LSSR SWQDLKD MR+ GEVT+ADAHK R+N+GV+EF + SDMK A++K DG E+
Sbjct: 107 IVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVN 166
Query: 543 GYNLKVHED 569
G +++ ED
Sbjct: 167 GRKIRLVED 175
>sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4
Length = 489
Score = 168 bits (426), Expect = 2e-41
Identities = 89/189 (47%), Positives = 117/189 (61%)
Frame = +3
Query: 3 PRLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLL 182
PR+YIG L + ERD+++FF+ YG+I VDLKNGYGFVE DD RDA+DA+++L+G L
Sbjct: 2 PRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLC 61
Query: 183 GERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRI 362
GERV VE AR P R+E+R+
Sbjct: 62 GERVIVEHARG---------------PRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRL 106
Query: 363 IVDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELY 542
IV+ LSSR SWQDLKD MR+ GEVT+ADAHK R+N+GV+EF + SDMK A++K DG E+
Sbjct: 107 IVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVN 166
Query: 543 GYNLKVHED 569
G +++ ED
Sbjct: 167 GRKIRLVED 175
>sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor
SRP40) (Insulin-induced growth response protein CL-4)
(Delayed-early protein HRS)
Length = 269
Score = 161 bits (408), Expect = 2e-39
Identities = 83/187 (44%), Positives = 117/187 (62%)
Frame = +3
Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185
R++IG L E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64
Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365
ERVT+E AR+ + P+R+E+R+I
Sbjct: 65 ERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAP-------------PVRTENRLI 111
Query: 366 VDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYG 545
V+ LSSRVSWQDLKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K G E+ G
Sbjct: 112 VENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEING 171
Query: 546 YNLKVHE 566
+K+ E
Sbjct: 172 RKIKLIE 178
>sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor
SRP40) (Delayed-early protein HRS)
Length = 272
Score = 161 bits (408), Expect = 2e-39
Identities = 83/187 (44%), Positives = 117/187 (62%)
Frame = +3
Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185
R++IG L E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64
Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365
ERVT+E AR+ + P+R+E+R+I
Sbjct: 65 ERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAP-------------PVRTENRLI 111
Query: 366 VDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYG 545
V+ LSSRVSWQDLKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K G E+ G
Sbjct: 112 VENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEING 171
Query: 546 YNLKVHE 566
+K+ E
Sbjct: 172 RKIKLIE 178
>sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor
SRP40) (Delayed-early protein HRS)
Length = 270
Score = 145 bits (367), Expect = 1e-34
Identities = 75/172 (43%), Positives = 106/172 (61%)
Frame = +3
Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185
R++IG L E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64
Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365
ERVT+E AR+ + ++ +R+I
Sbjct: 65 ERVTIEHARARS-------------RGGRGRGRYSDRLAVADLGNDRRKCSTCKNRNRLI 111
Query: 366 VDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDK 521
V+ LSSRVSWQDLKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K
Sbjct: 112 VENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEK 163
>sp|Q23121|RSP1_CAEEL Probable splicing factor, arginine/serine-rich 1 (RNA-binding
protein srp-5) (CeSRp75)
Length = 312
Score = 142 bits (359), Expect = 9e-34
Identities = 80/198 (40%), Positives = 113/198 (57%), Gaps = 10/198 (5%)
Frame = +3
Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185
R+YIG L R+ E+DI+ FFR YG+IR V LKNG+GFVE DD+RDAEDA+HDL+G +L G
Sbjct: 4 RIYIGRLTSRVSEKDIEHFFRGYGQIRDVLLKNGFGFVEFDDKRDAEDAVHDLNGKELGG 63
Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIR------ 347
ERV ++ ++ P R
Sbjct: 64 ERVILDYSKPRGGGGDRGGFGGGGRGGARVSSYSGGGGGGRDRFDRYDRGPPRRESRYGR 123
Query: 348 ---SEHRIIVDGLSSRVSWQDLKDLMRKVG-EVTFADAHKLRQNQGVVEFSNSSDMKAAI 515
+ HR++V+ LSSR+SWQDLKD +R+ G E T+A+AHK R N+ ++ F+ SD+K I
Sbjct: 124 PYSTRHRVVVENLSSRISWQDLKDQVRRQGVEPTYAEAHK-RPNEALLCFATPSDLKRCI 182
Query: 516 DKYDGYELYGYNLKVHED 569
+K DG +L G +K+ +D
Sbjct: 183 EKCDGMDLNGRKIKMIDD 200
>sp|Q23120|RSP2_CAEEL Probable splicing factor, arginine/serine-rich 2 (RNA-binding
protein srp-4) (CeSRp40)
Length = 281
Score = 135 bits (339), Expect = 2e-31
Identities = 70/189 (37%), Positives = 107/189 (56%), Gaps = 1/189 (0%)
Frame = +3
Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185
R+YIG LP R +RD++ FFR YG++ V +KNG+GFV+ D+RDA+DA+HDL+G +L G
Sbjct: 3 RVYIGRLPNRASDRDVEHFFRGYGKLSDVIMKNGFGFVDFQDQRDADDAVHDLNGKELCG 62
Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365
ERV +E R +P + R++
Sbjct: 63 ERVILEFPRRKV-------GYNEERSGSGFRGREPTFRKGGERQFSNRYSRPCSTRFRLV 115
Query: 366 VDGLSSRVSWQDLKDLMRKVG-EVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELY 542
+D LS+R SWQD+KD +RK+G E T+++AHK NQ +V F++ D++ A++K G +L
Sbjct: 116 IDNLSTRYSWQDIKDHIRKLGIEPTYSEAHKRNVNQAIVCFTSHDDLRDAMNKLQGEDLN 175
Query: 543 GYNLKVHED 569
G LK ++
Sbjct: 176 GRKLKCTDE 184
>sp|P78814|SRP2_SCHPO Pre-mRNA splicing factor srp2
Length = 365
Score = 125 bits (315), Expect = 1e-28
Identities = 68/188 (36%), Positives = 95/188 (50%)
Frame = +3
Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185
RL++G +P + D+ FF+ YG+I L NG+GFVE++D RDA D ++D G + +G
Sbjct: 5 RLFVGRIPPQATREDMMDFFKGYGQILDCKLMNGFGFVEVEDARDARDIVNDFQGKEFMG 64
Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365
R+ VE AR +P R+ R+I
Sbjct: 65 SRIVVEPARGERRRRENFRESAASKYP-----------------------RPRRTGFRLI 101
Query: 366 VDGLSSRVSWQDLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYG 545
V+ LS VSWQDLKD+MRK GE TF DAH+ GVVEFS DM+ A+ +G + G
Sbjct: 102 VENLSEDVSWQDLKDVMRKAGEPTFTDAHRENPGAGVVEFSTEEDMRNALTSLNGEVIKG 161
Query: 546 YNLKVHED 569
+ + ED
Sbjct: 162 QAVTLRED 169
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,769,078
Number of Sequences: 369166
Number of extensions: 1302602
Number of successful extensions: 4096
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3682
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4010
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8245425915
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)