Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_022_O07 (455 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (E... 78 8e-15 sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich... 77 2e-14 sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich... 76 3e-14 sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4 76 3e-14 sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5... 67 2e-11 sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich... 67 2e-11 sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich... 58 1e-08 sp|P78814|SRP2_SCHPO Pre-mRNA splicing factor srp2 56 3e-08 sp|Q9P2K5|MYEF2_HUMAN Myelin expression factor 2 (MyEF-2) (... 44 1e-04 sp|Q8C854|MYEF2_MOUSE Myelin expression factor 2 (MyEF-2) (... 44 1e-04
>sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (Enhancer of deformed) (52-kDa bracketing protein) (B52 protein) Length = 376 Score = 78.2 bits (191), Expect = 8e-15 Identities = 38/61 (62%), Positives = 47/61 (77%) Frame = +3 Query: 240 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHEDRGG 419 DLKD MR+ GEVT+ADAHK R+N+GVVEF++ SDMK AI+K D EL G + + EDR G Sbjct: 135 DLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLVEDRRG 194 Query: 420 G 422 G Sbjct: 195 G 195
>sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich 6 (Pre-mRNA splicing factor SRP55) Length = 344 Score = 77.0 bits (188), Expect = 2e-14 Identities = 35/58 (60%), Positives = 46/58 (79%) Frame = +3 Query: 240 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHEDR 413 DLKD MR+ GEVT+ADAHK R N+GV+EF + SDMK A+DK DG E+ G N+++ ED+ Sbjct: 125 DLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDK 182
>sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich 4 (Pre-mRNA splicing factor SRP75) (SRP001LB) Length = 494 Score = 76.3 bits (186), Expect = 3e-14 Identities = 35/64 (54%), Positives = 49/64 (76%) Frame = +3 Query: 240 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHEDRGG 419 DLKD MR+ GEVT+ADAHK R+N+GV+EF + SDMK A++K DG E+ G +++ ED+ G Sbjct: 119 DLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPG 178 Query: 420 GMKR 431 +R Sbjct: 179 SRRR 182
>sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4 Length = 489 Score = 76.3 bits (186), Expect = 3e-14 Identities = 35/64 (54%), Positives = 49/64 (76%) Frame = +3 Query: 240 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHEDRGG 419 DLKD MR+ GEVT+ADAHK R+N+GV+EF + SDMK A++K DG E+ G +++ ED+ G Sbjct: 119 DLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPG 178 Query: 420 GMKR 431 +R Sbjct: 179 SRRR 182
>sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor SRP40) (Insulin-induced growth response protein CL-4) (Delayed-early protein HRS) Length = 269 Score = 67.0 bits (162), Expect = 2e-11 Identities = 35/70 (50%), Positives = 48/70 (68%) Frame = +3 Query: 240 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHEDRGG 419 DLKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K G E+ G +K+ E Sbjct: 123 DLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE---- 178 Query: 420 GMKRNLEVAR 449 G KR+ +R Sbjct: 179 GSKRHRSRSR 188
>sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor SRP40) (Delayed-early protein HRS) Length = 272 Score = 66.6 bits (161), Expect = 2e-11 Identities = 34/65 (52%), Positives = 46/65 (70%) Frame = +3 Query: 240 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHEDRGG 419 DLKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K G E+ G +K+ E Sbjct: 123 DLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE---- 178 Query: 420 GMKRN 434 G KR+ Sbjct: 179 GSKRH 183
>sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor SRP40) (Delayed-early protein HRS) Length = 270 Score = 57.8 bits (138), Expect = 1e-08 Identities = 26/41 (63%), Positives = 34/41 (82%) Frame = +3 Query: 240 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDK 362 DLKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K Sbjct: 123 DLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEK 163
>sp|P78814|SRP2_SCHPO Pre-mRNA splicing factor srp2 Length = 365 Score = 56.2 bits (134), Expect = 3e-08 Identities = 27/57 (47%), Positives = 35/57 (61%) Frame = +3 Query: 240 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 410 DLKD+MRK GE TF DAH+ GVVEFS DM+ A+ +G + G + + ED Sbjct: 113 DLKDVMRKAGEPTFTDAHRENPGAGVVEFSTEEDMRNALTSLNGEVIKGQAVTLRED 169
>sp|Q9P2K5|MYEF2_HUMAN Myelin expression factor 2 (MyEF-2) (MST156) Length = 600 Score = 44.3 bits (103), Expect = 1e-04 Identities = 28/64 (43%), Positives = 37/64 (57%), Gaps = 5/64 (7%) Frame = +3 Query: 243 LKDLMR-KVGEVT----FADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHE 407 +KDLMR KVGEVT F DA + GVVEF + +K A++ + Y+L G L + E Sbjct: 116 IKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKE 175 Query: 408 DRGG 419 D G Sbjct: 176 DPDG 179
>sp|Q8C854|MYEF2_MOUSE Myelin expression factor 2 (MyEF-2) (MEF-2) Length = 591 Score = 44.3 bits (103), Expect = 1e-04 Identities = 28/64 (43%), Positives = 37/64 (57%), Gaps = 5/64 (7%) Frame = +3 Query: 243 LKDLMR-KVGEVT----FADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHE 407 +KDLMR KVGEVT F DA + GVVEF + +K A++ + Y+L G L + E Sbjct: 107 IKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKE 166 Query: 408 DRGG 419 D G Sbjct: 167 DPDG 170
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 52,855,205 Number of Sequences: 369166 Number of extensions: 1012385 Number of successful extensions: 1866 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1820 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1861 length of database: 68,354,980 effective HSP length: 101 effective length of database: 49,696,745 effective search space used: 2484837250 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)