Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_012_E07 (701 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich... 64 3e-10 sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (E... 61 3e-09 sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich... 60 6e-09 sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4 60 6e-09 sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5... 54 3e-07 sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich... 54 3e-07 sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich... 46 1e-04 sp|P78814|SRP2_SCHPO Pre-mRNA splicing factor srp2 44 4e-04 sp|Q9P2K5|MYEF2_HUMAN Myelin expression factor 2 (MyEF-2) (... 37 0.039 sp|Q8C854|MYEF2_MOUSE Myelin expression factor 2 (MyEF-2) (... 37 0.039
>sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich 6 (Pre-mRNA splicing factor SRP55) Length = 344 Score = 64.3 bits (155), Expect = 3e-10 Identities = 29/50 (58%), Positives = 39/50 (78%) Frame = +1 Query: 1 KVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 150 + GEVT+ADAHK R N+GV+EF + SDMK A+DK DG E+ G N+++ ED Sbjct: 132 QAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIED 181
>sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (Enhancer of deformed) (52-kDa bracketing protein) (B52 protein) Length = 376 Score = 60.8 bits (146), Expect = 3e-09 Identities = 29/50 (58%), Positives = 38/50 (76%) Frame = +1 Query: 1 KVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 150 + GEVT+ADAHK R+N+GVVEF++ SDMK AI+K D EL G + + ED Sbjct: 142 QAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLVED 191
>sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich 4 (Pre-mRNA splicing factor SRP75) (SRP001LB) Length = 494 Score = 60.1 bits (144), Expect = 6e-09 Identities = 27/50 (54%), Positives = 39/50 (78%) Frame = +1 Query: 1 KVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 150 + GEVT+ADAHK R+N+GV+EF + SDMK A++K DG E+ G +++ ED Sbjct: 126 QAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED 175
>sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4 Length = 489 Score = 60.1 bits (144), Expect = 6e-09 Identities = 27/50 (54%), Positives = 39/50 (78%) Frame = +1 Query: 1 KVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 150 + GEVT+ADAHK R+N+GV+EF + SDMK A++K DG E+ G +++ ED Sbjct: 126 QAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED 175
>sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor SRP40) (Insulin-induced growth response protein CL-4) (Delayed-early protein HRS) Length = 269 Score = 54.3 bits (129), Expect = 3e-07 Identities = 25/49 (51%), Positives = 36/49 (73%) Frame = +1 Query: 1 KVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHE 147 + GEVTFADAH+ + N+GVVEF++ D+K AI+K G E+ G +K+ E Sbjct: 130 QAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE 178
>sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor SRP40) (Delayed-early protein HRS) Length = 272 Score = 54.3 bits (129), Expect = 3e-07 Identities = 25/49 (51%), Positives = 36/49 (73%) Frame = +1 Query: 1 KVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHE 147 + GEVTFADAH+ + N+GVVEF++ D+K AI+K G E+ G +K+ E Sbjct: 130 QAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE 178
>sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor SRP40) (Delayed-early protein HRS) Length = 270 Score = 45.8 bits (107), Expect = 1e-04 Identities = 20/34 (58%), Positives = 28/34 (82%) Frame = +1 Query: 1 KVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDK 102 + GEVTFADAH+ + N+GVVEF++ D+K AI+K Sbjct: 130 QAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEK 163
>sp|P78814|SRP2_SCHPO Pre-mRNA splicing factor srp2 Length = 365 Score = 43.9 bits (102), Expect = 4e-04 Identities = 21/50 (42%), Positives = 28/50 (56%) Frame = +1 Query: 1 KVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 150 K GE TF DAH+ GVVEFS DM+ A+ +G + G + + ED Sbjct: 120 KAGEPTFTDAHRENPGAGVVEFSTEEDMRNALTSLNGEVIKGQAVTLRED 169
>sp|Q9P2K5|MYEF2_HUMAN Myelin expression factor 2 (MyEF-2) (MST156) Length = 600 Score = 37.4 bits (85), Expect = 0.039 Identities = 22/54 (40%), Positives = 30/54 (55%), Gaps = 4/54 (7%) Frame = +1 Query: 1 KVGEVT----FADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 150 KVGEVT F DA + GVVEF + +K A++ + Y+L G L + ED Sbjct: 123 KVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKED 176
>sp|Q8C854|MYEF2_MOUSE Myelin expression factor 2 (MyEF-2) (MEF-2) Length = 591 Score = 37.4 bits (85), Expect = 0.039 Identities = 22/54 (40%), Positives = 30/54 (55%), Gaps = 4/54 (7%) Frame = +1 Query: 1 KVGEVT----FADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 150 KVGEVT F DA + GVVEF + +K A++ + Y+L G L + ED Sbjct: 114 KVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKED 167
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.303 0.125 0.356 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 51,810,285 Number of Sequences: 369166 Number of extensions: 786148 Number of successful extensions: 1229 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1209 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1229 length of database: 68,354,980 effective HSP length: 107 effective length of database: 48,588,335 effective search space used: 6122130210 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.8 bits)