Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00824 (749 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q5R1W6|TKT_PANTR Transketolase (TK) 289 5e-78 sp|Q60HC7|TKT_MACFA Transketolase (TK) 289 5e-78 sp|P29401|TKT_HUMAN Transketolase (TK) 289 6e-78 sp|P50137|TKT_RAT Transketolase (TK) 288 1e-77 sp|Q6B855|TKT_BOVIN Transketolase (TK) 287 2e-77 sp|P40142|TKT_MOUSE Transketolase (TK) (P68) 286 5e-77 sp|P51854|TKT2_HUMAN Transketolase-like 1 (Transketolase 2)... 247 2e-65 sp|Q58092|TKTC_METJA Putative transketolase C-terminal sect... 139 6e-33 sp|P55573|Y4MN_RHISN Hypothetical transketolase family prot... 106 8e-23 sp|Q88QG7|DXS_PSEPK 1-deoxy-D-xylulose-5-phosphate synthase... 90 7e-18
>sp|Q5R1W6|TKT_PANTR Transketolase (TK) Length = 623 Score = 289 bits (740), Expect = 5e-78 Identities = 140/224 (62%), Positives = 176/224 (78%) Frame = +1 Query: 1 FDHIRMGAVSQTDCNFAGSHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEK 180 FD IRM A+S+++ N GSH GVSIGEDGPSQMALEDLAMFRS+P STVFYPSD VATEK Sbjct: 397 FDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEK 456 Query: 181 SVELAANTKGICFIRTGRPNTPVIYKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEAL 360 +VELAANTKGICFIRT RP +IY N+E F++G+AKV+ S++DQ T++ AGVTL+EAL Sbjct: 457 AVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVILKSKDDQVTVIGAGVTLHEAL 516 Query: 361 KAADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSAL 540 AA+ L K +N+RV+D FTIKP+D +L+ A T+G +LTVEDHY EGG+GEAV+SA+ Sbjct: 517 AAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAV 576 Query: 541 ASEAGVIVKKLAVNGVPRSGQPEELLALFKIDASSIHDAITAMV 672 E G+ V LAVN VPRSG+P ELL +F ID +I A+ ++ Sbjct: 577 VGEPGITVTHLAVNRVPRSGKPAELLKMFGIDKDAIAQAVRGLI 620
>sp|Q60HC7|TKT_MACFA Transketolase (TK) Length = 623 Score = 289 bits (740), Expect = 5e-78 Identities = 140/224 (62%), Positives = 177/224 (79%) Frame = +1 Query: 1 FDHIRMGAVSQTDCNFAGSHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEK 180 FD IRM A+S+++ N GSH GVSIGEDGPSQMALEDLAMFRS+P STVFYPSD VATEK Sbjct: 397 FDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEK 456 Query: 181 SVELAANTKGICFIRTGRPNTPVIYKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEAL 360 +VELAANTKGICFIRT RP +IY N+E F++G+AKV+ S++DQ T++ AGVTL+EAL Sbjct: 457 AVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEAL 516 Query: 361 KAADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSAL 540 AA++L K +N+RV+D FTIKP+D +L+ A T+G +LTVEDHY EGG+GEAV+SA+ Sbjct: 517 AAAESLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAV 576 Query: 541 ASEAGVIVKKLAVNGVPRSGQPEELLALFKIDASSIHDAITAMV 672 E G+ V LAVN VPRSG+P ELL +F ID +I A+ ++ Sbjct: 577 VGEPGITVTHLAVNRVPRSGKPAELLKMFGIDKDAIAQAVKGLI 620
>sp|P29401|TKT_HUMAN Transketolase (TK) Length = 623 Score = 289 bits (739), Expect = 6e-78 Identities = 140/224 (62%), Positives = 176/224 (78%) Frame = +1 Query: 1 FDHIRMGAVSQTDCNFAGSHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEK 180 FD IRM A+S+++ N GSH GVSIGEDGPSQMALEDLAMFRS+P STVFYPSD VATEK Sbjct: 397 FDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEK 456 Query: 181 SVELAANTKGICFIRTGRPNTPVIYKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEAL 360 +VELAANTKGICFIRT RP +IY N+E F++G+AKV+ S++DQ T++ AGVTL+EAL Sbjct: 457 AVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEAL 516 Query: 361 KAADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSAL 540 AA+ L K +N+RV+D FTIKP+D +L+ A T+G +LTVEDHY EGG+GEAV+SA+ Sbjct: 517 AAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAV 576 Query: 541 ASEAGVIVKKLAVNGVPRSGQPEELLALFKIDASSIHDAITAMV 672 E G+ V LAVN VPRSG+P ELL +F ID +I A+ ++ Sbjct: 577 VGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLI 620
>sp|P50137|TKT_RAT Transketolase (TK) Length = 623 Score = 288 bits (736), Expect = 1e-77 Identities = 140/224 (62%), Positives = 177/224 (79%) Frame = +1 Query: 1 FDHIRMGAVSQTDCNFAGSHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEK 180 FD IRM A+S+++ N GSH GVSIGEDGPSQMALEDLAMFRS+P STVFYPSD VATEK Sbjct: 397 FDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEK 456 Query: 181 SVELAANTKGICFIRTGRPNTPVIYKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEAL 360 +VELAANTKGICFIRT RP +IY N+E F++G+AKV+ S++DQ T++ AGVTL+EAL Sbjct: 457 AVELAANTKGICFIRTSRPENAIIYSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEAL 516 Query: 361 KAADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSAL 540 AA+ L K + VRV+D FTIKP+D++L+ CA T+G +LTVEDHY EGG+GEAV++ + Sbjct: 517 AAAEMLKKEKIGVRVLDPFTIKPLDKKLILDCARATKGRILTVEDHYYEGGIGEAVSAVV 576 Query: 541 ASEAGVIVKKLAVNGVPRSGQPEELLALFKIDASSIHDAITAMV 672 E GV V +LAV+ VPRSG+P ELL +F ID +I A+ +V Sbjct: 577 VGEPGVTVTRLAVSQVPRSGKPAELLKMFGIDKDAIVQAVKGLV 620
>sp|Q6B855|TKT_BOVIN Transketolase (TK) Length = 623 Score = 287 bits (735), Expect = 2e-77 Identities = 142/224 (63%), Positives = 176/224 (78%) Frame = +1 Query: 1 FDHIRMGAVSQTDCNFAGSHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEK 180 FD IRM A+S+++ N GSH GVSIGEDGPSQMALEDLAMFRSIP STVFYPSD VATEK Sbjct: 397 FDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSIPMSTVFYPSDGVATEK 456 Query: 181 SVELAANTKGICFIRTGRPNTPVIYKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEAL 360 +VELAANTKGICFIRT RP +IYK E F+IG+AKV+ +++DQ T++ AGVTL+EAL Sbjct: 457 AVELAANTKGICFIRTSRPENAIIYKQHEDFQIGQAKVVLKNKDDQVTVIGAGVTLHEAL 516 Query: 361 KAADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSAL 540 AAD L + +N+RV+D FTIKP+D++L+ A T+G +LTVEDHY EGG+GEAV SA+ Sbjct: 517 AAADLLKREKINIRVLDPFTIKPLDKKLILDSARATKGRILTVEDHYYEGGIGEAVASAV 576 Query: 541 ASEAGVIVKKLAVNGVPRSGQPEELLALFKIDASSIHDAITAMV 672 E GV V +LAV+ VPRSG+P ELL +F ID +I A+ +V Sbjct: 577 VGEPGVTVTRLAVSQVPRSGKPAELLKMFGIDRDAIAQAVRGLV 620
>sp|P40142|TKT_MOUSE Transketolase (TK) (P68) Length = 623 Score = 286 bits (731), Expect = 5e-77 Identities = 139/224 (62%), Positives = 178/224 (79%) Frame = +1 Query: 1 FDHIRMGAVSQTDCNFAGSHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEK 180 FD IRM A+S+++ N GSH GVSIGEDGPSQMALEDLAMFRS+P STVFYPSD VATEK Sbjct: 397 FDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEK 456 Query: 181 SVELAANTKGICFIRTGRPNTPVIYKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEAL 360 +VELAANTKGICFIRT RP +IY N+E F++G+AKV+ S++DQ T++ AGVTL+EAL Sbjct: 457 AVELAANTKGICFIRTSRPENAIIYSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEAL 516 Query: 361 KAADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSAL 540 AA++L K +++RV+D FTIKP+D +L+ A T+G +LTVEDHY EGG+GEAV++A+ Sbjct: 517 AAAESLKKDKISIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSAAV 576 Query: 541 ASEAGVIVKKLAVNGVPRSGQPEELLALFKIDASSIHDAITAMV 672 E GV V +LAV+ VPRSG+P ELL +F ID +I A+ +V Sbjct: 577 VGEPGVTVTRLAVSQVPRSGKPAELLKMFGIDKDAIVQAVKGLV 620
>sp|P51854|TKT2_HUMAN Transketolase-like 1 (Transketolase 2) (TK 2) (Transketolase related protein) Length = 557 Score = 247 bits (631), Expect = 2e-65 Identities = 125/241 (51%), Positives = 168/241 (69%), Gaps = 17/241 (7%) Frame = +1 Query: 1 FDHIRMGAVSQTDCNFAGSHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEK 180 FDHIR+G +++++ N GSH GVS+G+DG SQMALED+AMFR+IP T+FYP+DAV+TE Sbjct: 315 FDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEH 374 Query: 181 SVELAANTKGICFIRTGRPNTPVIYKNDEHFEIGKA-----------------KVLRSSQ 309 +V LAAN KG+CFIRT RP T VIY E FEIG+A KVLR Sbjct: 375 AVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKGVSMLQDSWSSVISYQKVLRHCV 434 Query: 310 NDQATIVSAGVTLYEALKAADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTV 489 +D+ T++ AG+T+YEAL AAD L K + +RV+DLFTIKP+D + A T G ++TV Sbjct: 435 SDKVTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITV 494 Query: 490 EDHYPEGGLGEAVTSALASEAGVIVKKLAVNGVPRSGQPEELLALFKIDASSIHDAITAM 669 EDHYP+GG+GEAV +A++ + + V LAV+GVP+SG+ EELL ++ I A I A+ M Sbjct: 495 EDHYPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCM 554 Query: 670 V 672 + Sbjct: 555 L 555
>sp|Q58092|TKTC_METJA Putative transketolase C-terminal section (TK) Length = 316 Score = 139 bits (351), Expect = 6e-33 Identities = 81/215 (37%), Positives = 127/215 (59%), Gaps = 6/215 (2%) Frame = +1 Query: 22 AVSQTDCNFAGSHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAAN 201 A + + +H G+++GEDG S ED+A+ R+IP V P+D T+ + A Sbjct: 99 AYPKLNVKIVATHAGITVGEDGASHQMCEDIAIMRAIPNMVVIAPTDYYHTKNVIRTIAE 158 Query: 202 TKGICFIRTGRPNTPVIYKNDEH--FEIGKAKVLRSSQNDQATIVSAGVTLYEALKAADT 375 KG ++R R +T +IY+N+E FEIGK K+L ++ TI++ G + EAL+A + Sbjct: 159 YKGPVYVRMPRRDTEIIYENEEEATFEIGKGKILVDGED--LTIIATGEEVPEALRAGEI 216 Query: 376 LHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAG 555 L ++G++ +V++ TIKPIDEE+++K ++ V+TVEDH GGLG AV +AS Sbjct: 217 LKENGISAEIVEMATIKPIDEEIIKK----SKDFVVTVEDHSIIGGLGGAVAEVIASNG- 271 Query: 556 VIVKKLAVNGV----PRSGQPEELLALFKIDASSI 648 + KKL G+ RSG+ +ELL + +D SI Sbjct: 272 -LNKKLLRIGINDVFGRSGKADELLKYYGLDGESI 305
>sp|P55573|Y4MN_RHISN Hypothetical transketolase family protein y4mN Length = 345 Score = 106 bits (264), Expect = 8e-23 Identities = 64/158 (40%), Positives = 96/158 (60%), Gaps = 2/158 (1%) Frame = +1 Query: 85 GPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGRPNTPVIYKN- 261 GPS A ED+AMFR +P T+ P DA E++V A +G ++R R N P++ + Sbjct: 146 GPSHQATEDIAMFRGMPNLTIIDPCDASEIEQAVPAIAAHEGPVYMRLLRGNVPLVLEEY 205 Query: 262 DEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALKAADTLHKSGVNVRVVDLFTIKPIDE- 438 FE+GKAK+LR ++ I+S+G+ AL+AA+ L K+G++ V+ + TIKP+DE Sbjct: 206 GYRFELGKAKLLRDGRD--TLIISSGLMTMRALEAAEELRKNGIDAGVLHVPTIKPLDEA 263 Query: 439 ELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEA 552 +L +CA + R V+ E+H GGLGEAV + L A Sbjct: 264 TILAECARQGR-LVVVAENHTVIGGLGEAVAATLMRSA 300
>sp|Q88QG7|DXS_PSEPK 1-deoxy-D-xylulose-5-phosphate synthase (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS) Length = 631 Score = 89.7 bits (221), Expect = 7e-18 Identities = 76/224 (33%), Positives = 113/224 (50%), Gaps = 9/224 (4%) Frame = +1 Query: 22 AVSQTDCNFAGSHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAAN 201 AV D FA G+ +GEDGP+ DL+ R IPG V PSD K + Sbjct: 415 AVQNLDVLFAIDRAGL-VGEDGPTHAGSYDLSYLRCIPGMLVMTPSDENELRKMLSTGHL 473 Query: 202 TKGICFIRTGR---PNTPVIYKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALKAAD 372 G +R R PN P I + + EIGK V R Q ++ ++ GV L EA++ A+ Sbjct: 474 YNGPAAVRYPRGTGPNAP-ISGDLQPLEIGKGVVRR--QGEKVALLVFGVQLAEAMQVAE 530 Query: 373 TLHKSGVNVRVVDLFTIKPIDEELLRKCA--HETRGHVLTVEDHYPEGGLGEAVTSALAS 546 +N VVD+ +KP+DE L+ + A HE ++T+E++ GG G AV LAS Sbjct: 531 Q-----INATVVDMRFVKPLDEALVLELAGSHEL---LVTIEENAIMGGAGAAVGEFLAS 582 Query: 547 EAGVIVKKLAVNGVP----RSGQPEELLALFKIDASSIHDAITA 666 +A ++K L G+P +P ++LA +DA+ I ++ A Sbjct: 583 QA--VLKPLLHLGLPDIYVEHAKPAQMLAECGLDAAGIEASVKA 624
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 84,826,757 Number of Sequences: 369166 Number of extensions: 1649952 Number of successful extensions: 4991 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4736 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4883 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 6824907600 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)