Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_A16
(603 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q60HC7|TKT_MACFA Transketolase (TK) 215 6e-56
sp|Q5R1W6|TKT_PANTR Transketolase (TK) 215 8e-56
sp|P29401|TKT_HUMAN Transketolase (TK) 214 1e-55
sp|P50137|TKT_RAT Transketolase (TK) 214 2e-55
sp|Q6B855|TKT_BOVIN Transketolase (TK) 213 3e-55
sp|P40142|TKT_MOUSE Transketolase (TK) (P68) 212 7e-55
sp|P51854|TKT2_HUMAN Transketolase-like 1 (Transketolase 2)... 181 1e-45
sp|Q58092|TKTC_METJA Putative transketolase C-terminal sect... 107 2e-23
sp|P55573|Y4MN_RHISN Hypothetical transketolase family prot... 82 1e-15
sp|P73067|DXS_SYNY3 1-deoxy-D-xylulose-5-phosphate synthase... 69 1e-11
>sp|Q60HC7|TKT_MACFA Transketolase (TK)
Length = 623
Score = 215 bits (548), Expect = 6e-56
Identities = 103/175 (58%), Positives = 135/175 (77%)
Frame = +3
Query: 9 FYPSDAVATEKSVELAANTKGICFIRTGRPNTPVIYKNDEHFEIGKAKVLRSSQNDQATI 188
FYPSD VATEK+VELAANTKGICFIRT RP +IY N+E F++G+AKV+ S++DQ T+
Sbjct: 446 FYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTV 505
Query: 189 VSAGVTLYEALKAADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPE 368
+ AGVTL+EAL AA++L K +N+RV+D FTIKP+D +L+ A T+G +LTVEDHY E
Sbjct: 506 IGAGVTLHEALAAAESLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYE 565
Query: 369 GGLGEAVTSALASEAGVIVKKLAVNGVPRSGQPEELLALFKIDASSIHDAITAMV 533
GG+GEAV+SA+ E G+ V LAVN VPRSG+P ELL +F ID +I A+ ++
Sbjct: 566 GGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDKDAIAQAVKGLI 620
>sp|Q5R1W6|TKT_PANTR Transketolase (TK)
Length = 623
Score = 215 bits (547), Expect = 8e-56
Identities = 103/175 (58%), Positives = 134/175 (76%)
Frame = +3
Query: 9 FYPSDAVATEKSVELAANTKGICFIRTGRPNTPVIYKNDEHFEIGKAKVLRSSQNDQATI 188
FYPSD VATEK+VELAANTKGICFIRT RP +IY N+E F++G+AKV+ S++DQ T+
Sbjct: 446 FYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVILKSKDDQVTV 505
Query: 189 VSAGVTLYEALKAADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPE 368
+ AGVTL+EAL AA+ L K +N+RV+D FTIKP+D +L+ A T+G +LTVEDHY E
Sbjct: 506 IGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYE 565
Query: 369 GGLGEAVTSALASEAGVIVKKLAVNGVPRSGQPEELLALFKIDASSIHDAITAMV 533
GG+GEAV+SA+ E G+ V LAVN VPRSG+P ELL +F ID +I A+ ++
Sbjct: 566 GGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDKDAIAQAVRGLI 620
>sp|P29401|TKT_HUMAN Transketolase (TK)
Length = 623
Score = 214 bits (546), Expect = 1e-55
Identities = 103/175 (58%), Positives = 134/175 (76%)
Frame = +3
Query: 9 FYPSDAVATEKSVELAANTKGICFIRTGRPNTPVIYKNDEHFEIGKAKVLRSSQNDQATI 188
FYPSD VATEK+VELAANTKGICFIRT RP +IY N+E F++G+AKV+ S++DQ T+
Sbjct: 446 FYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTV 505
Query: 189 VSAGVTLYEALKAADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPE 368
+ AGVTL+EAL AA+ L K +N+RV+D FTIKP+D +L+ A T+G +LTVEDHY E
Sbjct: 506 IGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYE 565
Query: 369 GGLGEAVTSALASEAGVIVKKLAVNGVPRSGQPEELLALFKIDASSIHDAITAMV 533
GG+GEAV+SA+ E G+ V LAVN VPRSG+P ELL +F ID +I A+ ++
Sbjct: 566 GGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLI 620
>sp|P50137|TKT_RAT Transketolase (TK)
Length = 623
Score = 214 bits (544), Expect = 2e-55
Identities = 103/175 (58%), Positives = 135/175 (77%)
Frame = +3
Query: 9 FYPSDAVATEKSVELAANTKGICFIRTGRPNTPVIYKNDEHFEIGKAKVLRSSQNDQATI 188
FYPSD VATEK+VELAANTKGICFIRT RP +IY N+E F++G+AKV+ S++DQ T+
Sbjct: 446 FYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYSNNEDFQVGQAKVVLKSKDDQVTV 505
Query: 189 VSAGVTLYEALKAADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPE 368
+ AGVTL+EAL AA+ L K + VRV+D FTIKP+D++L+ CA T+G +LTVEDHY E
Sbjct: 506 IGAGVTLHEALAAAEMLKKEKIGVRVLDPFTIKPLDKKLILDCARATKGRILTVEDHYYE 565
Query: 369 GGLGEAVTSALASEAGVIVKKLAVNGVPRSGQPEELLALFKIDASSIHDAITAMV 533
GG+GEAV++ + E GV V +LAV+ VPRSG+P ELL +F ID +I A+ +V
Sbjct: 566 GGIGEAVSAVVVGEPGVTVTRLAVSQVPRSGKPAELLKMFGIDKDAIVQAVKGLV 620
>sp|Q6B855|TKT_BOVIN Transketolase (TK)
Length = 623
Score = 213 bits (542), Expect = 3e-55
Identities = 104/175 (59%), Positives = 134/175 (76%)
Frame = +3
Query: 9 FYPSDAVATEKSVELAANTKGICFIRTGRPNTPVIYKNDEHFEIGKAKVLRSSQNDQATI 188
FYPSD VATEK+VELAANTKGICFIRT RP +IYK E F+IG+AKV+ +++DQ T+
Sbjct: 446 FYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYKQHEDFQIGQAKVVLKNKDDQVTV 505
Query: 189 VSAGVTLYEALKAADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPE 368
+ AGVTL+EAL AAD L + +N+RV+D FTIKP+D++L+ A T+G +LTVEDHY E
Sbjct: 506 IGAGVTLHEALAAADLLKREKINIRVLDPFTIKPLDKKLILDSARATKGRILTVEDHYYE 565
Query: 369 GGLGEAVTSALASEAGVIVKKLAVNGVPRSGQPEELLALFKIDASSIHDAITAMV 533
GG+GEAV SA+ E GV V +LAV+ VPRSG+P ELL +F ID +I A+ +V
Sbjct: 566 GGIGEAVASAVVGEPGVTVTRLAVSQVPRSGKPAELLKMFGIDRDAIAQAVRGLV 620
>sp|P40142|TKT_MOUSE Transketolase (TK) (P68)
Length = 623
Score = 212 bits (539), Expect = 7e-55
Identities = 102/175 (58%), Positives = 136/175 (77%)
Frame = +3
Query: 9 FYPSDAVATEKSVELAANTKGICFIRTGRPNTPVIYKNDEHFEIGKAKVLRSSQNDQATI 188
FYPSD VATEK+VELAANTKGICFIRT RP +IY N+E F++G+AKV+ S++DQ T+
Sbjct: 446 FYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYSNNEDFQVGQAKVVLKSKDDQVTV 505
Query: 189 VSAGVTLYEALKAADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPE 368
+ AGVTL+EAL AA++L K +++RV+D FTIKP+D +L+ A T+G +LTVEDHY E
Sbjct: 506 IGAGVTLHEALAAAESLKKDKISIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYE 565
Query: 369 GGLGEAVTSALASEAGVIVKKLAVNGVPRSGQPEELLALFKIDASSIHDAITAMV 533
GG+GEAV++A+ E GV V +LAV+ VPRSG+P ELL +F ID +I A+ +V
Sbjct: 566 GGIGEAVSAAVVGEPGVTVTRLAVSQVPRSGKPAELLKMFGIDKDAIVQAVKGLV 620
>sp|P51854|TKT2_HUMAN Transketolase-like 1 (Transketolase 2) (TK 2) (Transketolase
related protein)
Length = 557
Score = 181 bits (460), Expect = 1e-45
Identities = 95/192 (49%), Positives = 127/192 (66%), Gaps = 17/192 (8%)
Frame = +3
Query: 9 FYPSDAVATEKSVELAANTKGICFIRTGRPNTPVIYKNDEHFEIGKAK------------ 152
FYP+DAV+TE +V LAAN KG+CFIRT RP T VIY E FEIG+AK
Sbjct: 364 FYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKGVSMLQDSWSSV 423
Query: 153 -----VLRSSQNDQATIVSAGVTLYEALKAADTLHKSGVNVRVVDLFTIKPIDEELLRKC 317
VLR +D+ T++ AG+T+YEAL AAD L K + +RV+DLFTIKP+D +
Sbjct: 424 ISYQKVLRHCVSDKVTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSS 483
Query: 318 AHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVIVKKLAVNGVPRSGQPEELLALFKID 497
A T G ++TVEDHYP+GG+GEAV +A++ + + V LAV+GVP+SG+ EELL ++ I
Sbjct: 484 AKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGIS 543
Query: 498 ASSIHDAITAMV 533
A I A+ M+
Sbjct: 544 ARHIIVAVKCML 555
>sp|Q58092|TKTC_METJA Putative transketolase C-terminal section (TK)
Length = 316
Score = 107 bits (267), Expect = 2e-23
Identities = 66/171 (38%), Positives = 103/171 (60%), Gaps = 6/171 (3%)
Frame = +3
Query: 15 PSDAVATEKSVELAANTKGICFIRTGRPNTPVIYKNDEH--FEIGKAKVLRSSQNDQATI 188
P+D T+ + A KG ++R R +T +IY+N+E FEIGK K+L ++ TI
Sbjct: 143 PTDYYHTKNVIRTIAEYKGPVYVRMPRRDTEIIYENEEEATFEIGKGKILVDGED--LTI 200
Query: 189 VSAGVTLYEALKAADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPE 368
++ G + EAL+A + L ++G++ +V++ TIKPIDEE+++K ++ V+TVEDH
Sbjct: 201 IATGEEVPEALRAGEILKENGISAEIVEMATIKPIDEEIIKK----SKDFVVTVEDHSII 256
Query: 369 GGLGEAVTSALASEAGVIVKKLAVNGV----PRSGQPEELLALFKIDASSI 509
GGLG AV +AS + KKL G+ RSG+ +ELL + +D SI
Sbjct: 257 GGLGGAVAEVIASNG--LNKKLLRIGINDVFGRSGKADELLKYYGLDGESI 305
>sp|P55573|Y4MN_RHISN Hypothetical transketolase family protein y4mN
Length = 345
Score = 81.6 bits (200), Expect = 1e-15
Identities = 52/135 (38%), Positives = 82/135 (60%), Gaps = 2/135 (1%)
Frame = +3
Query: 15 PSDAVATEKSVELAANTKGICFIRTGRPNTPVIYKNDEH-FEIGKAKVLRSSQNDQATIV 191
P DA E++V A +G ++R R N P++ + + FE+GKAK+LR ++ I+
Sbjct: 169 PCDASEIEQAVPAIAAHEGPVYMRLLRGNVPLVLEEYGYRFELGKAKLLRDGRD--TLII 226
Query: 192 SAGVTLYEALKAADTLHKSGVNVRVVDLFTIKPIDE-ELLRKCAHETRGHVLTVEDHYPE 368
S+G+ AL+AA+ L K+G++ V+ + TIKP+DE +L +CA + R V+ E+H
Sbjct: 227 SSGLMTMRALEAAEELRKNGIDAGVLHVPTIKPLDEATILAECARQGR-LVVVAENHTVI 285
Query: 369 GGLGEAVTSALASEA 413
GGLGEAV + L A
Sbjct: 286 GGLGEAVAATLMRSA 300
>sp|P73067|DXS_SYNY3 1-deoxy-D-xylulose-5-phosphate synthase
(1-deoxyxylulose-5-phosphate synthase) (DXP synthase)
(DXPS)
Length = 640
Score = 68.6 bits (166), Expect = 1e-11
Identities = 50/147 (34%), Positives = 77/147 (52%), Gaps = 5/147 (3%)
Frame = +3
Query: 15 PSDAVATEKSVELAAN-TKGICFIRTGRPN---TPVIYKNDEHFEIGKAKVLRSSQNDQA 182
P D ++ + N T G +R R N P++ + E EIGKA++LRS D
Sbjct: 451 PKDEAELQQMLVTGVNYTGGAIAMRYPRGNGIGVPLMEEGWEPLEIGKAEILRSG--DDV 508
Query: 183 TIVSAGVTLYEALKAADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHY 362
++ G +Y AL+ A+ LH+ G+ VV+ +KP+D EL+ A E G V+T+E+
Sbjct: 509 LLLGYGSMVYPALQTAELLHEHGIEATVVNARFVKPLDTELILPLA-ERIGKVVTMEEGC 567
Query: 363 PEGGLGEAVTSALASEAGVI-VKKLAV 440
GG G AV AL ++ +K+L V
Sbjct: 568 LMGGFGSAVAEALMDNNVLVPLKRLGV 594
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,734,313
Number of Sequences: 369166
Number of extensions: 1212699
Number of successful extensions: 3916
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3782
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3877
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4650991475
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)