Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_E15
(689 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5R1W6|TKT_PANTR Transketolase (TK) 269 6e-72
sp|Q60HC7|TKT_MACFA Transketolase (TK) 269 6e-72
sp|P29401|TKT_HUMAN Transketolase (TK) 268 8e-72
sp|P50137|TKT_RAT Transketolase (TK) 267 2e-71
sp|Q6B855|TKT_BOVIN Transketolase (TK) 267 2e-71
sp|P40142|TKT_MOUSE Transketolase (TK) (P68) 265 6e-71
sp|P51854|TKT2_HUMAN Transketolase-like 1 (Transketolase 2)... 227 3e-59
sp|Q58092|TKTC_METJA Putative transketolase C-terminal sect... 138 2e-32
sp|P55573|Y4MN_RHISN Hypothetical transketolase family prot... 105 9e-23
sp|P73067|DXS_SYNY3 1-deoxy-D-xylulose-5-phosphate synthase... 88 2e-17
>sp|Q5R1W6|TKT_PANTR Transketolase (TK)
Length = 623
Score = 269 bits (687), Expect = 6e-72
Identities = 131/206 (63%), Positives = 163/206 (79%)
Frame = +2
Query: 2 SHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGR 181
SH GVSIGEDGPSQMALEDLAMFRS+P STVFYPSD VATEK+VELAANTKGICFIRT R
Sbjct: 415 SHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSR 474
Query: 182 PNTPVIYKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDL 361
P +IY N+E F++G+AKV+ S++DQ T++ AGVTL+EAL AA+ L K +N+RV+D
Sbjct: 475 PENAIIYNNNEDFQVGQAKVILKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDP 534
Query: 362 FTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVIVKKLAVNGVPR 541
FTIKP+D +L+ A T+G +LTVEDHY EGG+GEAV+SA+ E G+ V LAVN VPR
Sbjct: 535 FTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPR 594
Query: 542 SGQPEELLALFKIDASSIHDAITAMV 619
SG+P ELL +F ID +I A+ ++
Sbjct: 595 SGKPAELLKMFGIDKDAIAQAVRGLI 620
>sp|Q60HC7|TKT_MACFA Transketolase (TK)
Length = 623
Score = 269 bits (687), Expect = 6e-72
Identities = 131/206 (63%), Positives = 164/206 (79%)
Frame = +2
Query: 2 SHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGR 181
SH GVSIGEDGPSQMALEDLAMFRS+P STVFYPSD VATEK+VELAANTKGICFIRT R
Sbjct: 415 SHCGVSIGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEKAVELAANTKGICFIRTSR 474
Query: 182 PNTPVIYKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDL 361
P +IY N+E F++G+AKV+ S++DQ T++ AGVTL+EAL AA++L K +N+RV+D
Sbjct: 475 PENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAESLKKEKINIRVLDP 534
Query: 362 FTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVIVKKLAVNGVPR 541
FTIKP+D +L+ A T+G +LTVEDHY EGG+GEAV+SA+ E G+ V LAVN VPR
Sbjct: 535 FTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPR 594
Query: 542 SGQPEELLALFKIDASSIHDAITAMV 619
SG+P ELL +F ID +I A+ ++
Sbjct: 595 SGKPAELLKMFGIDKDAIAQAVKGLI 620
>sp|P29401|TKT_HUMAN Transketolase (TK)
Length = 623
Score = 268 bits (686), Expect = 8e-72
Identities = 131/206 (63%), Positives = 163/206 (79%)
Frame = +2
Query: 2 SHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGR 181
SH GVSIGEDGPSQMALEDLAMFRS+P STVFYPSD VATEK+VELAANTKGICFIRT R
Sbjct: 415 SHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSR 474
Query: 182 PNTPVIYKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDL 361
P +IY N+E F++G+AKV+ S++DQ T++ AGVTL+EAL AA+ L K +N+RV+D
Sbjct: 475 PENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDP 534
Query: 362 FTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVIVKKLAVNGVPR 541
FTIKP+D +L+ A T+G +LTVEDHY EGG+GEAV+SA+ E G+ V LAVN VPR
Sbjct: 535 FTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPR 594
Query: 542 SGQPEELLALFKIDASSIHDAITAMV 619
SG+P ELL +F ID +I A+ ++
Sbjct: 595 SGKPAELLKMFGIDRDAIAQAVRGLI 620
>sp|P50137|TKT_RAT Transketolase (TK)
Length = 623
Score = 267 bits (683), Expect = 2e-71
Identities = 131/206 (63%), Positives = 164/206 (79%)
Frame = +2
Query: 2 SHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGR 181
SH GVSIGEDGPSQMALEDLAMFRS+P STVFYPSD VATEK+VELAANTKGICFIRT R
Sbjct: 415 SHCGVSIGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEKAVELAANTKGICFIRTSR 474
Query: 182 PNTPVIYKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDL 361
P +IY N+E F++G+AKV+ S++DQ T++ AGVTL+EAL AA+ L K + VRV+D
Sbjct: 475 PENAIIYSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAEMLKKEKIGVRVLDP 534
Query: 362 FTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVIVKKLAVNGVPR 541
FTIKP+D++L+ CA T+G +LTVEDHY EGG+GEAV++ + E GV V +LAV+ VPR
Sbjct: 535 FTIKPLDKKLILDCARATKGRILTVEDHYYEGGIGEAVSAVVVGEPGVTVTRLAVSQVPR 594
Query: 542 SGQPEELLALFKIDASSIHDAITAMV 619
SG+P ELL +F ID +I A+ +V
Sbjct: 595 SGKPAELLKMFGIDKDAIVQAVKGLV 620
>sp|Q6B855|TKT_BOVIN Transketolase (TK)
Length = 623
Score = 267 bits (682), Expect = 2e-71
Identities = 133/206 (64%), Positives = 163/206 (79%)
Frame = +2
Query: 2 SHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGR 181
SH GVSIGEDGPSQMALEDLAMFRSIP STVFYPSD VATEK+VELAANTKGICFIRT R
Sbjct: 415 SHCGVSIGEDGPSQMALEDLAMFRSIPMSTVFYPSDGVATEKAVELAANTKGICFIRTSR 474
Query: 182 PNTPVIYKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDL 361
P +IYK E F+IG+AKV+ +++DQ T++ AGVTL+EAL AAD L + +N+RV+D
Sbjct: 475 PENAIIYKQHEDFQIGQAKVVLKNKDDQVTVIGAGVTLHEALAAADLLKREKINIRVLDP 534
Query: 362 FTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVIVKKLAVNGVPR 541
FTIKP+D++L+ A T+G +LTVEDHY EGG+GEAV SA+ E GV V +LAV+ VPR
Sbjct: 535 FTIKPLDKKLILDSARATKGRILTVEDHYYEGGIGEAVASAVVGEPGVTVTRLAVSQVPR 594
Query: 542 SGQPEELLALFKIDASSIHDAITAMV 619
SG+P ELL +F ID +I A+ +V
Sbjct: 595 SGKPAELLKMFGIDRDAIAQAVRGLV 620
>sp|P40142|TKT_MOUSE Transketolase (TK) (P68)
Length = 623
Score = 265 bits (678), Expect = 6e-71
Identities = 130/206 (63%), Positives = 165/206 (80%)
Frame = +2
Query: 2 SHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGR 181
SH GVSIGEDGPSQMALEDLAMFRS+P STVFYPSD VATEK+VELAANTKGICFIRT R
Sbjct: 415 SHCGVSIGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEKAVELAANTKGICFIRTSR 474
Query: 182 PNTPVIYKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDL 361
P +IY N+E F++G+AKV+ S++DQ T++ AGVTL+EAL AA++L K +++RV+D
Sbjct: 475 PENAIIYSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAESLKKDKISIRVLDP 534
Query: 362 FTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVIVKKLAVNGVPR 541
FTIKP+D +L+ A T+G +LTVEDHY EGG+GEAV++A+ E GV V +LAV+ VPR
Sbjct: 535 FTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSAAVVGEPGVTVTRLAVSQVPR 594
Query: 542 SGQPEELLALFKIDASSIHDAITAMV 619
SG+P ELL +F ID +I A+ +V
Sbjct: 595 SGKPAELLKMFGIDKDAIVQAVKGLV 620
>sp|P51854|TKT2_HUMAN Transketolase-like 1 (Transketolase 2) (TK 2) (Transketolase related
protein)
Length = 557
Score = 227 bits (578), Expect = 3e-59
Identities = 117/223 (52%), Positives = 154/223 (69%), Gaps = 17/223 (7%)
Frame = +2
Query: 2 SHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGR 181
SH GVS+G+DG SQMALED+AMFR+IP T+FYP+DAV+TE +V LAAN KG+CFIRT R
Sbjct: 333 SHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGMCFIRTTR 392
Query: 182 PNTPVIYKNDEHFEIGKAK-----------------VLRSSQNDQATIVSAGVTLYEALN 310
P T VIY E FEIG+AK VLR +D+ T++ AG+T+YEAL
Sbjct: 393 PETMVIYTPQERFEIGQAKGVSMLQDSWSSVISYQKVLRHCVSDKVTVIGAGITVYEALA 452
Query: 311 AADTLHKSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALA 490
AAD L K + +RV+DLFTIKP+D + A T G ++TVEDHYP+GG+GEAV +A++
Sbjct: 453 AADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVS 512
Query: 491 SEAGVIVKKLAVNGVPRSGQPEELLALFKIDASSIHDAITAMV 619
+ + V LAV+GVP+SG+ EELL ++ I A I A+ M+
Sbjct: 513 MDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCML 555
>sp|Q58092|TKTC_METJA Putative transketolase C-terminal section (TK)
Length = 316
Score = 138 bits (347), Expect = 2e-32
Identities = 80/204 (39%), Positives = 123/204 (60%), Gaps = 6/204 (2%)
Frame = +2
Query: 2 SHVGVSIGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGR 181
+H G+++GEDG S ED+A+ R+IP V P+D T+ + A KG ++R R
Sbjct: 110 THAGITVGEDGASHQMCEDIAIMRAIPNMVVIAPTDYYHTKNVIRTIAEYKGPVYVRMPR 169
Query: 182 PNTPVIYKNDEH--FEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVV 355
+T +IY+N+E FEIGK K+L ++ TI++ G + EAL A + L ++G++ +V
Sbjct: 170 RDTEIIYENEEEATFEIGKGKILVDGED--LTIIATGEEVPEALRAGEILKENGISAEIV 227
Query: 356 DLFTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVIVKKLAVNGV 535
++ TIKPIDEE+++K ++ V+TVEDH GGLG AV +AS + KKL G+
Sbjct: 228 EMATIKPIDEEIIKK----SKDFVVTVEDHSIIGGLGGAVAEVIASNG--LNKKLLRIGI 281
Query: 536 ----PRSGQPEELLALFKIDASSI 595
RSG+ +ELL + +D SI
Sbjct: 282 NDVFGRSGKADELLKYYGLDGESI 305
>sp|P55573|Y4MN_RHISN Hypothetical transketolase family protein y4mN
Length = 345
Score = 105 bits (263), Expect = 9e-23
Identities = 64/158 (40%), Positives = 95/158 (60%), Gaps = 2/158 (1%)
Frame = +2
Query: 32 GPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGRPNTPVIYKN- 208
GPS A ED+AMFR +P T+ P DA E++V A +G ++R R N P++ +
Sbjct: 146 GPSHQATEDIAMFRGMPNLTIIDPCDASEIEQAVPAIAAHEGPVYMRLLRGNVPLVLEEY 205
Query: 209 DEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDLFTIKPIDE- 385
FE+GKAK+LR ++ I+S+G+ AL AA+ L K+G++ V+ + TIKP+DE
Sbjct: 206 GYRFELGKAKLLRDGRD--TLIISSGLMTMRALEAAEELRKNGIDAGVLHVPTIKPLDEA 263
Query: 386 ELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEA 499
+L +CA + R V+ E+H GGLGEAV + L A
Sbjct: 264 TILAECARQGR-LVVVAENHTVIGGLGEAVAATLMRSA 300
>sp|P73067|DXS_SYNY3 1-deoxy-D-xylulose-5-phosphate synthase
(1-deoxyxylulose-5-phosphate synthase) (DXP synthase)
(DXPS)
Length = 640
Score = 87.8 bits (216), Expect = 2e-17
Identities = 59/174 (33%), Positives = 90/174 (51%), Gaps = 5/174 (2%)
Frame = +2
Query: 20 IGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAAN-TKGICFIRTGRPN--- 187
+G DGP+ + D+A R IP + P D ++ + N T G +R R N
Sbjct: 424 VGADGPTHQGMYDIAYLRCIPNLVLMAPKDEAELQQMLVTGVNYTGGAIAMRYPRGNGIG 483
Query: 188 TPVIYKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDLFT 367
P++ + E EIGKA++LRS D ++ G +Y AL A+ LH+ G+ VV+
Sbjct: 484 VPLMEEGWEPLEIGKAEILRSG--DDVLLLGYGSMVYPALQTAELLHEHGIEATVVNARF 541
Query: 368 IKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVI-VKKLAV 526
+KP+D EL+ A E G V+T+E+ GG G AV AL ++ +K+L V
Sbjct: 542 VKPLDTELILPLA-ERIGKVVTMEEGCLMGGFGSAVAEALMDNNVLVPLKRLGV 594
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,138,996
Number of Sequences: 369166
Number of extensions: 1486475
Number of successful extensions: 4501
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4271
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4400
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5927776870
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)