Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_M12
(677 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5R1W6|TKT_PANTR Transketolase (TK) 259 5e-69
sp|Q60HC7|TKT_MACFA Transketolase (TK) 259 5e-69
sp|P29401|TKT_HUMAN Transketolase (TK) 259 6e-69
sp|P50137|TKT_RAT Transketolase (TK) 258 1e-68
sp|Q6B855|TKT_BOVIN Transketolase (TK) 257 2e-68
sp|P40142|TKT_MOUSE Transketolase (TK) (P68) 256 5e-68
sp|P51854|TKT2_HUMAN Transketolase-like 1 (Transketolase 2)... 217 2e-56
sp|Q58092|TKTC_METJA Putative transketolase C-terminal sect... 130 2e-30
sp|P55573|Y4MN_RHISN Hypothetical transketolase family prot... 105 8e-23
sp|P73067|DXS_SYNY3 1-deoxy-D-xylulose-5-phosphate synthase... 88 2e-17
>sp|Q5R1W6|TKT_PANTR Transketolase (TK)
Length = 623
Score = 259 bits (662), Expect = 5e-69
Identities = 126/200 (63%), Positives = 158/200 (79%)
Frame = +1
Query: 1 IGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGRPNTPVI 180
IGEDGPSQMALEDLAMFRS+P STVFYPSD VATEK+VELAANTKGICFIRT RP +I
Sbjct: 421 IGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII 480
Query: 181 YKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDLFTIKPI 360
Y N+E F++G+AKV+ S++DQ T++ AGVTL+EAL AA+ L K +N+RV+D FTIKP+
Sbjct: 481 YNNNEDFQVGQAKVILKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPL 540
Query: 361 DEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVIVKKLAVNGVPRSGQPEE 540
D +L+ A T+G +LTVEDHY EGG+GEAV+SA+ E G+ V LAVN VPRSG+P E
Sbjct: 541 DRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAE 600
Query: 541 LLALFKIDASSIHDAITAMV 600
LL +F ID +I A+ ++
Sbjct: 601 LLKMFGIDKDAIAQAVRGLI 620
>sp|Q60HC7|TKT_MACFA Transketolase (TK)
Length = 623
Score = 259 bits (662), Expect = 5e-69
Identities = 126/200 (63%), Positives = 159/200 (79%)
Frame = +1
Query: 1 IGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGRPNTPVI 180
IGEDGPSQMALEDLAMFRS+P STVFYPSD VATEK+VELAANTKGICFIRT RP +I
Sbjct: 421 IGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII 480
Query: 181 YKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDLFTIKPI 360
Y N+E F++G+AKV+ S++DQ T++ AGVTL+EAL AA++L K +N+RV+D FTIKP+
Sbjct: 481 YNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAESLKKEKINIRVLDPFTIKPL 540
Query: 361 DEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVIVKKLAVNGVPRSGQPEE 540
D +L+ A T+G +LTVEDHY EGG+GEAV+SA+ E G+ V LAVN VPRSG+P E
Sbjct: 541 DRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAE 600
Query: 541 LLALFKIDASSIHDAITAMV 600
LL +F ID +I A+ ++
Sbjct: 601 LLKMFGIDKDAIAQAVKGLI 620
>sp|P29401|TKT_HUMAN Transketolase (TK)
Length = 623
Score = 259 bits (661), Expect = 6e-69
Identities = 126/200 (63%), Positives = 158/200 (79%)
Frame = +1
Query: 1 IGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGRPNTPVI 180
IGEDGPSQMALEDLAMFRS+P STVFYPSD VATEK+VELAANTKGICFIRT RP +I
Sbjct: 421 IGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII 480
Query: 181 YKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDLFTIKPI 360
Y N+E F++G+AKV+ S++DQ T++ AGVTL+EAL AA+ L K +N+RV+D FTIKP+
Sbjct: 481 YNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPL 540
Query: 361 DEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVIVKKLAVNGVPRSGQPEE 540
D +L+ A T+G +LTVEDHY EGG+GEAV+SA+ E G+ V LAVN VPRSG+P E
Sbjct: 541 DRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAE 600
Query: 541 LLALFKIDASSIHDAITAMV 600
LL +F ID +I A+ ++
Sbjct: 601 LLKMFGIDRDAIAQAVRGLI 620
>sp|P50137|TKT_RAT Transketolase (TK)
Length = 623
Score = 258 bits (658), Expect = 1e-68
Identities = 126/200 (63%), Positives = 159/200 (79%)
Frame = +1
Query: 1 IGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGRPNTPVI 180
IGEDGPSQMALEDLAMFRS+P STVFYPSD VATEK+VELAANTKGICFIRT RP +I
Sbjct: 421 IGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII 480
Query: 181 YKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDLFTIKPI 360
Y N+E F++G+AKV+ S++DQ T++ AGVTL+EAL AA+ L K + VRV+D FTIKP+
Sbjct: 481 YSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAEMLKKEKIGVRVLDPFTIKPL 540
Query: 361 DEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVIVKKLAVNGVPRSGQPEE 540
D++L+ CA T+G +LTVEDHY EGG+GEAV++ + E GV V +LAV+ VPRSG+P E
Sbjct: 541 DKKLILDCARATKGRILTVEDHYYEGGIGEAVSAVVVGEPGVTVTRLAVSQVPRSGKPAE 600
Query: 541 LLALFKIDASSIHDAITAMV 600
LL +F ID +I A+ +V
Sbjct: 601 LLKMFGIDKDAIVQAVKGLV 620
>sp|Q6B855|TKT_BOVIN Transketolase (TK)
Length = 623
Score = 257 bits (657), Expect = 2e-68
Identities = 128/200 (64%), Positives = 158/200 (79%)
Frame = +1
Query: 1 IGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGRPNTPVI 180
IGEDGPSQMALEDLAMFRSIP STVFYPSD VATEK+VELAANTKGICFIRT RP +I
Sbjct: 421 IGEDGPSQMALEDLAMFRSIPMSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII 480
Query: 181 YKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDLFTIKPI 360
YK E F+IG+AKV+ +++DQ T++ AGVTL+EAL AAD L + +N+RV+D FTIKP+
Sbjct: 481 YKQHEDFQIGQAKVVLKNKDDQVTVIGAGVTLHEALAAADLLKREKINIRVLDPFTIKPL 540
Query: 361 DEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVIVKKLAVNGVPRSGQPEE 540
D++L+ A T+G +LTVEDHY EGG+GEAV SA+ E GV V +LAV+ VPRSG+P E
Sbjct: 541 DKKLILDSARATKGRILTVEDHYYEGGIGEAVASAVVGEPGVTVTRLAVSQVPRSGKPAE 600
Query: 541 LLALFKIDASSIHDAITAMV 600
LL +F ID +I A+ +V
Sbjct: 601 LLKMFGIDRDAIAQAVRGLV 620
>sp|P40142|TKT_MOUSE Transketolase (TK) (P68)
Length = 623
Score = 256 bits (653), Expect = 5e-68
Identities = 125/200 (62%), Positives = 160/200 (80%)
Frame = +1
Query: 1 IGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGRPNTPVI 180
IGEDGPSQMALEDLAMFRS+P STVFYPSD VATEK+VELAANTKGICFIRT RP +I
Sbjct: 421 IGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII 480
Query: 181 YKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDLFTIKPI 360
Y N+E F++G+AKV+ S++DQ T++ AGVTL+EAL AA++L K +++RV+D FTIKP+
Sbjct: 481 YSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAESLKKDKISIRVLDPFTIKPL 540
Query: 361 DEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVIVKKLAVNGVPRSGQPEE 540
D +L+ A T+G +LTVEDHY EGG+GEAV++A+ E GV V +LAV+ VPRSG+P E
Sbjct: 541 DRKLILDSARATKGRILTVEDHYYEGGIGEAVSAAVVGEPGVTVTRLAVSQVPRSGKPAE 600
Query: 541 LLALFKIDASSIHDAITAMV 600
LL +F ID +I A+ +V
Sbjct: 601 LLKMFGIDKDAIVQAVKGLV 620
>sp|P51854|TKT2_HUMAN Transketolase-like 1 (Transketolase 2) (TK 2) (Transketolase
related protein)
Length = 557
Score = 217 bits (553), Expect = 2e-56
Identities = 112/217 (51%), Positives = 149/217 (68%), Gaps = 17/217 (7%)
Frame = +1
Query: 1 IGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGRPNTPVI 180
+G+DG SQMALED+AMFR+IP T+FYP+DAV+TE +V LAAN KG+CFIRT RP T VI
Sbjct: 339 VGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVI 398
Query: 181 YKNDEHFEIGKAK-----------------VLRSSQNDQATIVSAGVTLYEALNAADTLH 309
Y E FEIG+AK VLR +D+ T++ AG+T+YEAL AAD L
Sbjct: 399 YTPQERFEIGQAKGVSMLQDSWSSVISYQKVLRHCVSDKVTVIGAGITVYEALAAADELS 458
Query: 310 KSGVNVRVVDLFTIKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVI 489
K + +RV+DLFTIKP+D + A T G ++TVEDHYP+GG+GEAV +A++ + +
Sbjct: 459 KQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQ 518
Query: 490 VKKLAVNGVPRSGQPEELLALFKIDASSIHDAITAMV 600
V LAV+GVP+SG+ EELL ++ I A I A+ M+
Sbjct: 519 VHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCML 555
>sp|Q58092|TKTC_METJA Putative transketolase C-terminal section (TK)
Length = 316
Score = 130 bits (328), Expect = 2e-30
Identities = 78/198 (39%), Positives = 118/198 (59%), Gaps = 6/198 (3%)
Frame = +1
Query: 1 IGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGRPNTPVI 180
+GEDG S ED+A+ R+IP V P+D T+ + A KG ++R R +T +I
Sbjct: 116 VGEDGASHQMCEDIAIMRAIPNMVVIAPTDYYHTKNVIRTIAEYKGPVYVRMPRRDTEII 175
Query: 181 YKNDEH--FEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDLFTIK 354
Y+N+E FEIGK K+L ++ TI++ G + EAL A + L ++G++ +V++ TIK
Sbjct: 176 YENEEEATFEIGKGKILVDGED--LTIIATGEEVPEALRAGEILKENGISAEIVEMATIK 233
Query: 355 PIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVIVKKLAVNGV----PR 522
PIDEE+++K ++ V+TVEDH GGLG AV +AS + KKL G+ R
Sbjct: 234 PIDEEIIKK----SKDFVVTVEDHSIIGGLGGAVAEVIASNG--LNKKLLRIGINDVFGR 287
Query: 523 SGQPEELLALFKIDASSI 576
SG+ +ELL + +D SI
Sbjct: 288 SGKADELLKYYGLDGESI 305
>sp|P55573|Y4MN_RHISN Hypothetical transketolase family protein y4mN
Length = 345
Score = 105 bits (263), Expect = 8e-23
Identities = 64/158 (40%), Positives = 95/158 (60%), Gaps = 2/158 (1%)
Frame = +1
Query: 13 GPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAANTKGICFIRTGRPNTPVIYKN- 189
GPS A ED+AMFR +P T+ P DA E++V A +G ++R R N P++ +
Sbjct: 146 GPSHQATEDIAMFRGMPNLTIIDPCDASEIEQAVPAIAAHEGPVYMRLLRGNVPLVLEEY 205
Query: 190 DEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDLFTIKPIDE- 366
FE+GKAK+LR ++ I+S+G+ AL AA+ L K+G++ V+ + TIKP+DE
Sbjct: 206 GYRFELGKAKLLRDGRD--TLIISSGLMTMRALEAAEELRKNGIDAGVLHVPTIKPLDEA 263
Query: 367 ELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEA 480
+L +CA + R V+ E+H GGLGEAV + L A
Sbjct: 264 TILAECARQGR-LVVVAENHTVIGGLGEAVAATLMRSA 300
>sp|P73067|DXS_SYNY3 1-deoxy-D-xylulose-5-phosphate synthase
(1-deoxyxylulose-5-phosphate synthase) (DXP synthase)
(DXPS)
Length = 640
Score = 87.8 bits (216), Expect = 2e-17
Identities = 59/174 (33%), Positives = 90/174 (51%), Gaps = 5/174 (2%)
Frame = +1
Query: 1 IGEDGPSQMALEDLAMFRSIPGSTVFYPSDAVATEKSVELAAN-TKGICFIRTGRPN--- 168
+G DGP+ + D+A R IP + P D ++ + N T G +R R N
Sbjct: 424 VGADGPTHQGMYDIAYLRCIPNLVLMAPKDEAELQQMLVTGVNYTGGAIAMRYPRGNGIG 483
Query: 169 TPVIYKNDEHFEIGKAKVLRSSQNDQATIVSAGVTLYEALNAADTLHKSGVNVRVVDLFT 348
P++ + E EIGKA++LRS D ++ G +Y AL A+ LH+ G+ VV+
Sbjct: 484 VPLMEEGWEPLEIGKAEILRSG--DDVLLLGYGSMVYPALQTAELLHEHGIEATVVNARF 541
Query: 349 IKPIDEELLRKCAHETRGHVLTVEDHYPEGGLGEAVTSALASEAGVI-VKKLAV 507
+KP+D EL+ A E G V+T+E+ GG G AV AL ++ +K+L V
Sbjct: 542 VKPLDTELILPLA-ERIGKVVTMEEGCLMGGFGSAVAEALMDNNVLVPLKRLGV 594
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,878,804
Number of Sequences: 369166
Number of extensions: 1458983
Number of successful extensions: 4458
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4232
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4357
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5733423530
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)