Planarian EST Database

DrC_00574

Cluster detail
GO Category : Not Available
Consensus Sequence :
>DrC_00574 CTACTTCCACCATTTATAAGAATTAATGTCGCGATTATATCCTACATTAGAAGACTTAAA AGTCGATGAATTAAAATCAGTGCAACATAACTTCATTAATACAGTGGTAAATGAACCTAC GGGGTCTCAAGGATCTTTATATCCTGCTTTAGATGATTATTTAGGATTGGATATGAGAGC TGCCCAAAATCAAATGGTACAGTCCTATGGAAATAGTGTTGTTGGTTATGGATGGCGTCA AAATACATCTGTAGTCGCACCCGTAACAAAGAATGATGTGGGCATTAGTAGAGCCGAAAT TAAACAAGGATTGCGTAGAGCTGTATTGTGTAAAGATTCTAAAGGTATTATTGGTTTACG TGTGCAAGCAGTTAATAAAGGTATATTTGTATCCTTTGTTAATGAAAATTCACCAGCTTC AATGGCTGGATTGCGATTTGGTGATCAAATTTTAGAAGTCAATAATCAAGTTGTTGCCGG TTGGACAACCGAAAAAGTTCACAAATTTTTTAAAGCGGCTGGATCCAATAATATTACTGT GGCATTACGTGATAGACCATTCGAACGAACTATTACAATGAATAAAGACAGCAATGGTTA TATTGGATTTGTTTTCAAAAATGGAACTATAACACATTTGGTTAAGGACAGTAGTGCTGC AAGAAATGGGCTGCTTATTGATCATAAATTAATTGAAATAAATGGCCAAAATGTTATAGG ATTAAAAGATAAAGAAATCCAGAAAATTATTGATAAAACACCTAATATTGTTACAGTTAC AATAATGCCTATGTTTGTATATGAACACATGGTTAAAACTCTGAGTTCAGATTTGCTAAA GAATCACATGCATCATAGTATTCCAGAAATTTAATATGGATAGTCATTTACTTTTCATCA TGACCTTTAACACTTCTTCGACGTC

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00574
         (925 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O00560|SDCB1_HUMAN  Syntenin-1 (Syndecan binding protein ...   288   1e-77
sp|Q9JI92|SDCB1_RAT  Syntenin-1 (Syndecan binding protein 1)      286   7e-77
sp|O08992|SDCB1_MOUSE  Syntenin-1 (Syndecan binding protein ...   284   2e-76
sp|Q99JZ0|SDCB2_MOUSE  Syntenin-2 (Syndecan binding protein 2)    257   3e-68
sp|Q9H190|SDCB2_HUMAN  Syntenin-2 (Syndecan binding protein 2)    251   2e-66
sp|O35430|APBA1_RAT  Amyloid beta A4 precursor protein-bindi...    61   4e-09
sp|Q02410|APBA1_HUMAN  Amyloid beta A4 precursor protein-bin...    60   7e-09
sp|Q99767|APBA2_HUMAN  Amyloid beta A4 precursor protein-bin...    55   2e-07
sp|Q5RD33|APBA2_PONPY  Amyloid beta A4 precursor protein-bin...    55   2e-07
sp|P98084|APBA2_MOUSE  Amyloid beta A4 precursor protein-bin...    55   2e-07

>sp|O00560|SDCB1_HUMAN Syntenin-1 (Syndecan binding protein 1) (Melanoma
           differentiation-associated protein 9) (MDA-9) (Scaffold
           protein Pbp1) (Pro-TGF-alpha cytoplasmic
           domain-interacting protein 18) (TACIP18)
          Length = 298

 Score =  288 bits (738), Expect = 1e-77
 Identities = 150/297 (50%), Positives = 201/297 (67%), Gaps = 18/297 (6%)
 Frame = +2

Query: 35  LYPTLEDLKVDELKSVQHNFINTVVNEPTGSQGS------------LYPALDDYLGLDMR 178
           LYP+LEDLKVD++   Q  F     N    S+ S            LYP L  Y+GL + 
Sbjct: 3   LYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLSLN 62

Query: 179 AAQ---NQMVQSYGNSVVGYGWRQNTSV---VAPVTKNDVGISRAEIKQGLRRAVLCKDS 340
             +   N  V S G  + G    + +S+   VAPVT NDVGI RAEIKQG+R  +LCKD 
Sbjct: 63  EEEIRANVAVVS-GAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKDQ 121

Query: 341 KGIIGLRVQAVNKGIFVSFVNENSPASMAGLRFGDQILEVNNQVVAGWTTEKVHKFFKAA 520
            G IGLR+++++ GIFV  V  NSPAS+ GLRFGDQ+L++N +  AGW+++K HK  K A
Sbjct: 122 DGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQA 181

Query: 521 GSNNITVALRDRPFERTITMNKDSNGYIGFVFKNGTITHLVKDSSAARNGLLIDHKLIEI 700
               IT+ +RDRPFERTITM+KDS G++GF+FKNG IT +VKDSSAARNGLL +H + EI
Sbjct: 182 FGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEI 241

Query: 701 NGQNVIGLKDKEIQKIIDKTPNIVTVTIMPMFVYEHMVKTLSSDLLKNHMHHSIPEI 871
           NGQNVIGLKD +I  I+  +  +VT+TIMP F++EH++K ++  ++K+ M H+IPE+
Sbjct: 242 NGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 298

>sp|Q9JI92|SDCB1_RAT Syntenin-1 (Syndecan binding protein 1)
          Length = 300

 Score =  286 bits (731), Expect = 7e-77
 Identities = 150/299 (50%), Positives = 202/299 (67%), Gaps = 20/299 (6%)
 Frame = +2

Query: 35  LYPTLEDLKVDELKSVQH-------------NFINTVVNEPTGS-QGSLYPALDDYLGLD 172
           LYP+LEDLKVD++   Q              N +++    P G+    LYP L  Y+GL 
Sbjct: 3   LYPSLEDLKVDKVIQAQTASSANPASQAFFLNVVDSAAFPPGGNLYPKLYPELSQYMGLS 62

Query: 173 MRAAQ---NQMVQSYGNSVVGYGWRQNTSV---VAPVTKNDVGISRAEIKQGLRRAVLCK 334
           +  A+   N  V S G    G    + +SV   VAPVT ND GI RAEIKQG+R  +LCK
Sbjct: 63  LSEAEICENMPVVS-GAPTQGQLVARPSSVNYMVAPVTGNDAGIRRAEIKQGIREVILCK 121

Query: 335 DSKGIIGLRVQAVNKGIFVSFVNENSPASMAGLRFGDQILEVNNQVVAGWTTEKVHKFFK 514
           D  G IGLR+++V+ GIFV  V  NSPAS+ GLRFGDQ+L++N +  AGW+++K HK  K
Sbjct: 122 DQDGKIGLRLKSVDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLK 181

Query: 515 AAGSNNITVALRDRPFERTITMNKDSNGYIGFVFKNGTITHLVKDSSAARNGLLIDHKLI 694
            A    IT+ +RDRPFERT+TM+KDS+G++GF+FK+G IT +VKDSSAARNGLL DH + 
Sbjct: 182 QAFGEKITMTIRDRPFERTVTMHKDSSGHVGFIFKSGKITSIVKDSSAARNGLLTDHHIC 241

Query: 695 EINGQNVIGLKDKEIQKIIDKTPNIVTVTIMPMFVYEHMVKTLSSDLLKNHMHHSIPEI 871
           EINGQNVIGLKD +I  I+     +VT+TIMP F++EH++K ++  ++K+ M H+IPE+
Sbjct: 242 EINGQNVIGLKDAQIADILSTAGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 300

>sp|O08992|SDCB1_MOUSE Syntenin-1 (Syndecan binding protein 1) (Scaffold protein Pbp1)
          Length = 299

 Score =  284 bits (727), Expect = 2e-76
 Identities = 146/297 (49%), Positives = 199/297 (67%), Gaps = 18/297 (6%)
 Frame = +2

Query: 35  LYPTLEDLKVDELKSVQHNFINTVVNE------------PTGS-QGSLYPALDDYLGLDM 175
           LYP+LEDLKVD++   Q  +     ++            P G+    LYP L  Y+GL +
Sbjct: 3   LYPSLEDLKVDKVIQAQTAYSANPASQAFVLVDASAALPPDGNLYPKLYPELSQYMGLSL 62

Query: 176 RAAQ--NQMVQSYGNSVVGYGWRQNTSV---VAPVTKNDVGISRAEIKQGLRRAVLCKDS 340
             A+    M    G    G    + +SV   VAPVT ND GI RAEIKQG+R  +LCKD 
Sbjct: 63  NEAEICESMPMVSGAPAQGQLVARPSSVNYMVAPVTGNDAGIRRAEIKQGIREVILCKDQ 122

Query: 341 KGIIGLRVQAVNKGIFVSFVNENSPASMAGLRFGDQILEVNNQVVAGWTTEKVHKFFKAA 520
            G IGLR+++++ GIFV  V  NSPAS+ GLRFGDQ+L++N +  AGW+++K HK  K A
Sbjct: 123 DGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQA 182

Query: 521 GSNNITVALRDRPFERTITMNKDSNGYIGFVFKNGTITHLVKDSSAARNGLLIDHKLIEI 700
               IT+ +RDRPFERT+TM+KDS+G++GF+FK+G IT +VKDSSAARNGLL DH + EI
Sbjct: 183 FGEKITMTIRDRPFERTVTMHKDSSGHVGFIFKSGKITSIVKDSSAARNGLLTDHHICEI 242

Query: 701 NGQNVIGLKDKEIQKIIDKTPNIVTVTIMPMFVYEHMVKTLSSDLLKNHMHHSIPEI 871
           NGQNVIGLKD +I  I+     +VT+TIMP F++EH++K ++  ++K+ M H+IPE+
Sbjct: 243 NGQNVIGLKDAQIADILSTAGTVVTITIMPTFIFEHIIKRMAPSIMKSLMDHTIPEV 299

>sp|Q99JZ0|SDCB2_MOUSE Syntenin-2 (Syndecan binding protein 2)
          Length = 292

 Score =  257 bits (657), Expect = 3e-68
 Identities = 142/296 (47%), Positives = 191/296 (64%), Gaps = 15/296 (5%)
 Frame = +2

Query: 26  MSRLYPTLEDLKVDELKSVQHNFINTVVNEPTGSQGS-----LYP---ALDDYLGLDMRA 181
           MS LYP+LEDLKV ++   Q     T+   P     +     LYP    L+ Y+GL + +
Sbjct: 1   MSVLYPSLEDLKVGQVIQAQGRASPTMPTLPAPMASAPPLSELYPNLAELESYMGLSLSS 60

Query: 182 AQNQ----MVQSYGNSVV---GYGWRQNTSVVAPVTKNDVGISRAEIKQGLRRAVLCKDS 340
            + Q     +    N VV   G G      VVAPV+ N++GI RAEIK G+R   LCKD 
Sbjct: 61  QEVQKNLTQIPDSDNMVVTSPGPG-----QVVAPVSGNNLGILRAEIKPGVREIHLCKDE 115

Query: 341 KGIIGLRVQAVNKGIFVSFVNENSPASMAGLRFGDQILEVNNQVVAGWTTEKVHKFFKAA 520
           +G  GLR+QAV+KG+FV  V  N+PAS+ GLRFGDQIL+++    AGW T K HK  K A
Sbjct: 116 RGKTGLRLQAVDKGLFVQLVQANTPASLVGLRFGDQILQIDGCDCAGWNTHKAHKVLKKA 175

Query: 521 GSNNITVALRDRPFERTITMNKDSNGYIGFVFKNGTITHLVKDSSAARNGLLIDHKLIEI 700
            +  I + +RDRPF+RT+TM+KDS+G +GF  K G I  +VK SSAARNGLL +H + E+
Sbjct: 176 SAEKIVMVIRDRPFQRTVTMHKDSSGQVGFSIKKGKIVSVVKGSSAARNGLLTNHYVCEV 235

Query: 701 NGQNVIGLKDKEIQKIIDKTPNIVTVTIMPMFVYEHMVKTLSSDLLKNHMHHSIPE 868
           NGQNVIGLKDK++ +I+    +++T+TI+P  +YEHM+K LS  LL + M HSIP+
Sbjct: 236 NGQNVIGLKDKKVTEILTTAGDVITLTIIPTVIYEHMIKRLSPLLLHHTMDHSIPD 291

>sp|Q9H190|SDCB2_HUMAN Syntenin-2 (Syndecan binding protein 2)
          Length = 292

 Score =  251 bits (641), Expect = 2e-66
 Identities = 138/294 (46%), Positives = 191/294 (64%), Gaps = 13/294 (4%)
 Frame = +2

Query: 26  MSRLYPTLEDLKVDELKSVQHNFINTVVNEPTGSQGS-----LYP---ALDDYLGLDMRA 181
           MS LYP+LEDLKVD+    Q      +   P  +        LYP    L++Y+GL + +
Sbjct: 1   MSSLYPSLEDLKVDQAIQAQVRASPKMPALPVQATAISPPPVLYPNLAELENYMGLSLSS 60

Query: 182 AQNQ-----MVQSYGNSVVGYGWRQNTSVVAPVTKNDVGISRAEIKQGLRRAVLCKDSKG 346
            + Q     + +    +V G G  Q   +VAPVT   +G+ RAEIK G+R   LCKD +G
Sbjct: 61  QEVQESLLQIPEGDSTAVSGPGPGQ---MVAPVTGYSLGVRRAEIKPGVREIHLCKDERG 117

Query: 347 IIGLRVQAVNKGIFVSFVNENSPASMAGLRFGDQILEVNNQVVAGWTTEKVHKFFKAAGS 526
             GLR++ V++G+FV  V  N+PAS+ GLRFGDQ+L+++ +  AGW++ K H+  K A  
Sbjct: 118 KTGLRLRKVDQGLFVQLVQANTPASLVGLRFGDQLLQIDGRDCAGWSSHKAHQVVKKASG 177

Query: 527 NNITVALRDRPFERTITMNKDSNGYIGFVFKNGTITHLVKDSSAARNGLLIDHKLIEING 706
           + I V +RDRPF+RT+TM+KDS G++GFV K G I  LVK SSAARNGLL +H + E++G
Sbjct: 178 DKIVVVVRDRPFQRTVTMHKDSMGHVGFVIKKGKIVSLVKGSSAARNGLLTNHYVCEVDG 237

Query: 707 QNVIGLKDKEIQKIIDKTPNIVTVTIMPMFVYEHMVKTLSSDLLKNHMHHSIPE 868
           QNVIGLKDK+I +I+    N+VT+TI+P  +YEHMVK L   LL + M HSIP+
Sbjct: 238 QNVIGLKDKKIMEILATAGNVVTLTIIPSVIYEHMVKKLPPVLLHHTMDHSIPD 291

>sp|O35430|APBA1_RAT Amyloid beta A4 precursor protein-binding family A member 1
            (Neuron-specific X11 protein) (Neuronal
            Munc18-1-interacting protein 1) (Mint-1) (Adapter protein
            X11alpha)
          Length = 839

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 38/144 (26%), Positives = 68/144 (47%), Gaps = 4/144 (2%)
 Frame = +2

Query: 383  IFVSFVNENSPASMAG-LRFGDQILEVNNQVVAGW---TTEKVHKFFKAAGSNNITVALR 550
            + ++ +    PA  +G L  GDQI+ +N   + G    T + + K  K      + + +R
Sbjct: 685  VIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNI-VR 743

Query: 551  DRPFERTITMNKDSNGYIGFVFKNGTITHLVKDSSAARNGLLIDHKLIEINGQNVIGLKD 730
              P    +    D    +GF  +NG I  L++   A R G+ + H++IEINGQ+V+    
Sbjct: 744  CPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPH 803

Query: 731  KEIQKIIDKTPNIVTVTIMPMFVY 802
            ++I  I+      + +  MP  +Y
Sbjct: 804  EKIVHILSNAVGEIHMKTMPAAMY 827

>sp|Q02410|APBA1_HUMAN Amyloid beta A4 precursor protein-binding family A member 1
            (Neuron-specific X11 protein) (Neuronal
            Munc18-1-interacting protein 1) (Mint-1) (Adapter protein
            X11alpha)
          Length = 837

 Score = 60.5 bits (145), Expect = 7e-09
 Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 4/144 (2%)
 Frame = +2

Query: 383  IFVSFVNENSPASMAG-LRFGDQILEVNNQVVAGWTTEKVHKFFKAAGSNNITVAL---R 550
            + ++ +    PA  +G L  GDQI+ +N   + G          K    N   V L   R
Sbjct: 683  VIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGL-ENQSRVKLNIVR 741

Query: 551  DRPFERTITMNKDSNGYIGFVFKNGTITHLVKDSSAARNGLLIDHKLIEINGQNVIGLKD 730
              P    +    D    +GF  +NG I  L++   A R G+ + H++IEINGQ+V+    
Sbjct: 742  CPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPH 801

Query: 731  KEIQKIIDKTPNIVTVTIMPMFVY 802
            ++I  I+      + +  MP  +Y
Sbjct: 802  EKIVHILSNAVGEIHMKTMPAAMY 825

>sp|Q99767|APBA2_HUMAN Amyloid beta A4 precursor protein-binding family A member 2
            (Neuron-specific X11L protein) (Neuronal
            Munc18-1-interacting protein 2) (Mint-2) (Adapter protein
            X11beta)
          Length = 749

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 34/142 (23%), Positives = 64/142 (45%), Gaps = 2/142 (1%)
 Frame = +2

Query: 383  IFVSFVNENSPASMAGLRFGDQILEVNNQVVAGWTTEKVHKFFKAA-GSNNITVALRDRP 559
            I  + +N    A    L  GDQI+ +N   + G          K       + + +   P
Sbjct: 596  ILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCP 655

Query: 560  FERTITMNKDSNGY-IGFVFKNGTITHLVKDSSAARNGLLIDHKLIEINGQNVIGLKDKE 736
               T+ + +    Y +GF  +NG I  L++   A R G+ + H++IEINGQ+V+    ++
Sbjct: 656  PVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEK 715

Query: 737  IQKIIDKTPNIVTVTIMPMFVY 802
            I + +  +   + +  MP  ++
Sbjct: 716  IVQALSNSVGEIHMKTMPAAMF 737

>sp|Q5RD33|APBA2_PONPY Amyloid beta A4 precursor protein-binding family A member 2
          Length = 749

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 34/142 (23%), Positives = 64/142 (45%), Gaps = 2/142 (1%)
 Frame = +2

Query: 383  IFVSFVNENSPASMAGLRFGDQILEVNNQVVAGWTTEKVHKFFKAA-GSNNITVALRDRP 559
            I  + +N    A    L  GDQI+ +N   + G          K       + + +   P
Sbjct: 596  ILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCP 655

Query: 560  FERTITMNKDSNGY-IGFVFKNGTITHLVKDSSAARNGLLIDHKLIEINGQNVIGLKDKE 736
               T+ + +    Y +GF  +NG I  L++   A R G+ + H++IEINGQ+V+    ++
Sbjct: 656  PVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEK 715

Query: 737  IQKIIDKTPNIVTVTIMPMFVY 802
            I + +  +   + +  MP  ++
Sbjct: 716  IVQALSNSVGEIHMKTMPAAMF 737

>sp|P98084|APBA2_MOUSE Amyloid beta A4 precursor protein-binding family A member 2
            (Neuron-specific X11L protein) (Neuronal
            Munc18-1-interacting protein 2) (Mint-2) (Adapter protein
            X11beta)
          Length = 750

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 34/142 (23%), Positives = 64/142 (45%), Gaps = 2/142 (1%)
 Frame = +2

Query: 383  IFVSFVNENSPASMAGLRFGDQILEVNNQVVAGWTTEKVHKFFKAA-GSNNITVALRDRP 559
            I  + +N    A    L  GDQI+ +N   + G          K       + + +   P
Sbjct: 597  ILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCP 656

Query: 560  FERTITMNKDSNGY-IGFVFKNGTITHLVKDSSAARNGLLIDHKLIEINGQNVIGLKDKE 736
               T+ + +    Y +GF  +NG I  L++   A R G+ + H++IEINGQ+V+    ++
Sbjct: 657  PVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEK 716

Query: 737  IQKIIDKTPNIVTVTIMPMFVY 802
            I + +  +   + +  MP  ++
Sbjct: 717  IVQALSNSVGEIHMKTMPAAMF 738

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 103,219,543
Number of Sequences: 369166
Number of extensions: 2102592
Number of successful extensions: 5875
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5495
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5838
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9462723610
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00574

Planaria EST Database

DrC_00574

BLASTX 2.2.13 [Nov-27-2005]

Cluster detail