Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_P04
(613 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O00560|SDCB1_HUMAN Syntenin-1 (Syndecan binding protein ... 236 3e-62
sp|Q9JI92|SDCB1_RAT Syntenin-1 (Syndecan binding protein 1) 234 2e-61
sp|O08992|SDCB1_MOUSE Syntenin-1 (Syndecan binding protein ... 233 2e-61
sp|Q99JZ0|SDCB2_MOUSE Syntenin-2 (Syndecan binding protein 2) 209 4e-54
sp|Q9H190|SDCB2_HUMAN Syntenin-2 (Syndecan binding protein 2) 204 2e-52
sp|O35430|APBA1_RAT Amyloid beta A4 precursor protein-bindi... 57 5e-08
sp|Q02410|APBA1_HUMAN Amyloid beta A4 precursor protein-bin... 56 8e-08
sp|Q99767|APBA2_HUMAN Amyloid beta A4 precursor protein-bin... 52 9e-07
sp|Q5RD33|APBA2_PONPY Amyloid beta A4 precursor protein-bin... 52 9e-07
sp|P98084|APBA2_MOUSE Amyloid beta A4 precursor protein-bin... 52 9e-07
>sp|O00560|SDCB1_HUMAN Syntenin-1 (Syndecan binding protein 1) (Melanoma
differentiation-associated protein 9) (MDA-9) (Scaffold
protein Pbp1) (Pro-TGF-alpha cytoplasmic
domain-interacting protein 18) (TACIP18)
Length = 298
Score = 236 bits (603), Expect = 3e-62
Identities = 111/179 (62%), Positives = 141/179 (78%)
Frame = +2
Query: 77 VVAPVTKNDVGISRAEIKQGLRRAVLCKDSKGIIGLRVQAVNKGIFVSFVNENSPASMAG 256
+VAPVT NDVGI RAEIKQG+R +LCKD G IGLR+++++ GIFV V NSPAS+ G
Sbjct: 92 MVAPVTGNDVGIRRAEIKQGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVG 151
Query: 257 LRFGDQILEVNNQVVAGWTTEKVHKFFKAAGSNNITVALRDRPFERTITMNKDSNGYIGF 436
LRFGDQ+L++N + AGW+++K HK K A IT+ +RDRPFERTITM+KDS G++GF
Sbjct: 152 LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTITMHKDSTGHVGF 211
Query: 437 VFKNGTITHLVKDSSAARNGLLIDHKLIEINGQNVIGLKDKEIQKIIDKTPNIVTVTIM 613
+FKNG IT +VKDSSAARNGLL +H + EINGQNVIGLKD +I I+ + +VT+TIM
Sbjct: 212 IFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTITIM 270
>sp|Q9JI92|SDCB1_RAT Syntenin-1 (Syndecan binding protein 1)
Length = 300
Score = 234 bits (596), Expect = 2e-61
Identities = 110/179 (61%), Positives = 140/179 (78%)
Frame = +2
Query: 77 VVAPVTKNDVGISRAEIKQGLRRAVLCKDSKGIIGLRVQAVNKGIFVSFVNENSPASMAG 256
+VAPVT ND GI RAEIKQG+R +LCKD G IGLR+++V+ GIFV V NSPAS+ G
Sbjct: 94 MVAPVTGNDAGIRRAEIKQGIREVILCKDQDGKIGLRLKSVDNGIFVQLVQANSPASLVG 153
Query: 257 LRFGDQILEVNNQVVAGWTTEKVHKFFKAAGSNNITVALRDRPFERTITMNKDSNGYIGF 436
LRFGDQ+L++N + AGW+++K HK K A IT+ +RDRPFERT+TM+KDS+G++GF
Sbjct: 154 LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTVTMHKDSSGHVGF 213
Query: 437 VFKNGTITHLVKDSSAARNGLLIDHKLIEINGQNVIGLKDKEIQKIIDKTPNIVTVTIM 613
+FK+G IT +VKDSSAARNGLL DH + EINGQNVIGLKD +I I+ +VT+TIM
Sbjct: 214 IFKSGKITSIVKDSSAARNGLLTDHHICEINGQNVIGLKDAQIADILSTAGTVVTITIM 272
>sp|O08992|SDCB1_MOUSE Syntenin-1 (Syndecan binding protein 1) (Scaffold protein Pbp1)
Length = 299
Score = 233 bits (595), Expect = 2e-61
Identities = 109/179 (60%), Positives = 140/179 (78%)
Frame = +2
Query: 77 VVAPVTKNDVGISRAEIKQGLRRAVLCKDSKGIIGLRVQAVNKGIFVSFVNENSPASMAG 256
+VAPVT ND GI RAEIKQG+R +LCKD G IGLR+++++ GIFV V NSPAS+ G
Sbjct: 93 MVAPVTGNDAGIRRAEIKQGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVG 152
Query: 257 LRFGDQILEVNNQVVAGWTTEKVHKFFKAAGSNNITVALRDRPFERTITMNKDSNGYIGF 436
LRFGDQ+L++N + AGW+++K HK K A IT+ +RDRPFERT+TM+KDS+G++GF
Sbjct: 153 LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTVTMHKDSSGHVGF 212
Query: 437 VFKNGTITHLVKDSSAARNGLLIDHKLIEINGQNVIGLKDKEIQKIIDKTPNIVTVTIM 613
+FK+G IT +VKDSSAARNGLL DH + EINGQNVIGLKD +I I+ +VT+TIM
Sbjct: 213 IFKSGKITSIVKDSSAARNGLLTDHHICEINGQNVIGLKDAQIADILSTAGTVVTITIM 271
>sp|Q99JZ0|SDCB2_MOUSE Syntenin-2 (Syndecan binding protein 2)
Length = 292
Score = 209 bits (532), Expect = 4e-54
Identities = 100/179 (55%), Positives = 134/179 (74%)
Frame = +2
Query: 77 VVAPVTKNDVGISRAEIKQGLRRAVLCKDSKGIIGLRVQAVNKGIFVSFVNENSPASMAG 256
VVAPV+ N++GI RAEIK G+R LCKD +G GLR+QAV+KG+FV V N+PAS+ G
Sbjct: 86 VVAPVSGNNLGILRAEIKPGVREIHLCKDERGKTGLRLQAVDKGLFVQLVQANTPASLVG 145
Query: 257 LRFGDQILEVNNQVVAGWTTEKVHKFFKAAGSNNITVALRDRPFERTITMNKDSNGYIGF 436
LRFGDQIL+++ AGW T K HK K A + I + +RDRPF+RT+TM+KDS+G +GF
Sbjct: 146 LRFGDQILQIDGCDCAGWNTHKAHKVLKKASAEKIVMVIRDRPFQRTVTMHKDSSGQVGF 205
Query: 437 VFKNGTITHLVKDSSAARNGLLIDHKLIEINGQNVIGLKDKEIQKIIDKTPNIVTVTIM 613
K G I +VK SSAARNGLL +H + E+NGQNVIGLKDK++ +I+ +++T+TI+
Sbjct: 206 SIKKGKIVSVVKGSSAARNGLLTNHYVCEVNGQNVIGLKDKKVTEILTTAGDVITLTII 264
>sp|Q9H190|SDCB2_HUMAN Syntenin-2 (Syndecan binding protein 2)
Length = 292
Score = 204 bits (518), Expect = 2e-52
Identities = 97/179 (54%), Positives = 134/179 (74%)
Frame = +2
Query: 77 VVAPVTKNDVGISRAEIKQGLRRAVLCKDSKGIIGLRVQAVNKGIFVSFVNENSPASMAG 256
+VAPVT +G+ RAEIK G+R LCKD +G GLR++ V++G+FV V N+PAS+ G
Sbjct: 86 MVAPVTGYSLGVRRAEIKPGVREIHLCKDERGKTGLRLRKVDQGLFVQLVQANTPASLVG 145
Query: 257 LRFGDQILEVNNQVVAGWTTEKVHKFFKAAGSNNITVALRDRPFERTITMNKDSNGYIGF 436
LRFGDQ+L+++ + AGW++ K H+ K A + I V +RDRPF+RT+TM+KDS G++GF
Sbjct: 146 LRFGDQLLQIDGRDCAGWSSHKAHQVVKKASGDKIVVVVRDRPFQRTVTMHKDSMGHVGF 205
Query: 437 VFKNGTITHLVKDSSAARNGLLIDHKLIEINGQNVIGLKDKEIQKIIDKTPNIVTVTIM 613
V K G I LVK SSAARNGLL +H + E++GQNVIGLKDK+I +I+ N+VT+TI+
Sbjct: 206 VIKKGKIVSLVKGSSAARNGLLTNHYVCEVDGQNVIGLKDKKIMEILATAGNVVTLTII 264
>sp|O35430|APBA1_RAT Amyloid beta A4 precursor protein-binding family A member 1
(Neuron-specific X11 protein) (Neuronal
Munc18-1-interacting protein 1) (Mint-1) (Adapter protein
X11alpha)
Length = 839
Score = 56.6 bits (135), Expect = 5e-08
Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 4/127 (3%)
Frame = +2
Query: 209 IFVSFVNENSPASMAG-LRFGDQILEVNNQVVAGW---TTEKVHKFFKAAGSNNITVALR 376
+ ++ + PA +G L GDQI+ +N + G T + + K K + + +R
Sbjct: 685 VIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNI-VR 743
Query: 377 DRPFERTITMNKDSNGYIGFVFKNGTITHLVKDSSAARNGLLIDHKLIEINGQNVIGLKD 556
P + D +GF +NG I L++ A R G+ + H++IEINGQ+V+
Sbjct: 744 CPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPH 803
Query: 557 KEIQKII 577
++I I+
Sbjct: 804 EKIVHIL 810
>sp|Q02410|APBA1_HUMAN Amyloid beta A4 precursor protein-binding family A member 1
(Neuron-specific X11 protein) (Neuronal
Munc18-1-interacting protein 1) (Mint-1) (Adapter protein
X11alpha)
Length = 837
Score = 55.8 bits (133), Expect = 8e-08
Identities = 36/127 (28%), Positives = 58/127 (45%), Gaps = 4/127 (3%)
Frame = +2
Query: 209 IFVSFVNENSPASMAG-LRFGDQILEVNNQVVAGWTTEKVHKFFKAAGSNNITVAL---R 376
+ ++ + PA +G L GDQI+ +N + G K N V L R
Sbjct: 683 VIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGL-ENQSRVKLNIVR 741
Query: 377 DRPFERTITMNKDSNGYIGFVFKNGTITHLVKDSSAARNGLLIDHKLIEINGQNVIGLKD 556
P + D +GF +NG I L++ A R G+ + H++IEINGQ+V+
Sbjct: 742 CPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPH 801
Query: 557 KEIQKII 577
++I I+
Sbjct: 802 EKIVHIL 808
>sp|Q99767|APBA2_HUMAN Amyloid beta A4 precursor protein-binding family A member 2
(Neuron-specific X11L protein) (Neuronal
Munc18-1-interacting protein 2) (Mint-2) (Adapter
protein X11beta)
Length = 749
Score = 52.4 bits (124), Expect = 9e-07
Identities = 32/128 (25%), Positives = 58/128 (45%), Gaps = 2/128 (1%)
Frame = +2
Query: 209 IFVSFVNENSPASMAGLRFGDQILEVNNQVVAGWTTEKVHKFFKAA-GSNNITVALRDRP 385
I + +N A L GDQI+ +N + G K + + + P
Sbjct: 596 ILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCP 655
Query: 386 FERTITMNKDSNGY-IGFVFKNGTITHLVKDSSAARNGLLIDHKLIEINGQNVIGLKDKE 562
T+ + + Y +GF +NG I L++ A R G+ + H++IEINGQ+V+ ++
Sbjct: 656 PVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEK 715
Query: 563 IQKIIDKT 586
I + + +
Sbjct: 716 IVQALSNS 723
>sp|Q5RD33|APBA2_PONPY Amyloid beta A4 precursor protein-binding family A member 2
Length = 749
Score = 52.4 bits (124), Expect = 9e-07
Identities = 32/128 (25%), Positives = 58/128 (45%), Gaps = 2/128 (1%)
Frame = +2
Query: 209 IFVSFVNENSPASMAGLRFGDQILEVNNQVVAGWTTEKVHKFFKAA-GSNNITVALRDRP 385
I + +N A L GDQI+ +N + G K + + + P
Sbjct: 596 ILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCP 655
Query: 386 FERTITMNKDSNGY-IGFVFKNGTITHLVKDSSAARNGLLIDHKLIEINGQNVIGLKDKE 562
T+ + + Y +GF +NG I L++ A R G+ + H++IEINGQ+V+ ++
Sbjct: 656 PVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEK 715
Query: 563 IQKIIDKT 586
I + + +
Sbjct: 716 IVQALSNS 723
>sp|P98084|APBA2_MOUSE Amyloid beta A4 precursor protein-binding family A member 2
(Neuron-specific X11L protein) (Neuronal
Munc18-1-interacting protein 2) (Mint-2) (Adapter
protein X11beta)
Length = 750
Score = 52.4 bits (124), Expect = 9e-07
Identities = 32/128 (25%), Positives = 58/128 (45%), Gaps = 2/128 (1%)
Frame = +2
Query: 209 IFVSFVNENSPASMAGLRFGDQILEVNNQVVAGWTTEKVHKFFKAA-GSNNITVALRDRP 385
I + +N A L GDQI+ +N + G K + + + P
Sbjct: 597 ILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCP 656
Query: 386 FERTITMNKDSNGY-IGFVFKNGTITHLVKDSSAARNGLLIDHKLIEINGQNVIGLKDKE 562
T+ + + Y +GF +NG I L++ A R G+ + H++IEINGQ+V+ ++
Sbjct: 657 PVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEK 716
Query: 563 IQKIIDKT 586
I + + +
Sbjct: 717 IVQALSNS 724
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,564,260
Number of Sequences: 369166
Number of extensions: 1525312
Number of successful extensions: 4526
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4237
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4501
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4797864890
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)