Planaria EST Database

DrC_00212

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00212
         (1426 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P33198|IDHP_PIG  Isocitrate dehydrogenase [NADP], mitocho...   653   0.0  
sp|P48735|IDHP_HUMAN  Isocitrate dehydrogenase [NADP], mitoc...   650   0.0  
sp|Q04467|IDHP_BOVIN  Isocitrate dehydrogenase [NADP], mitoc...   647   0.0  
sp|P54071|IDHP_MOUSE  Isocitrate dehydrogenase [NADP], mitoc...   624   e-178
sp|Q9Z2K9|IDHC_MICME  Isocitrate dehydrogenase [NADP] cytopl...   605   e-172
sp|P41562|IDHC_RAT  Isocitrate dehydrogenase [NADP] cytoplas...   603   e-172
sp|Q9Z2K8|IDHC_MICOH  Isocitrate dehydrogenase [NADP] cytopl...   603   e-172
sp|O75874|IDHC_HUMAN  Isocitrate dehydrogenase [NADP] cytopl...   602   e-172
sp|O88844|IDHC_MOUSE  Isocitrate dehydrogenase [NADP] cytopl...   593   e-169
sp|Q40345|IDHP_MEDSA  Isocitrate dehydrogenase [NADP], chlor...   586   e-167

>sp|P33198|IDHP_PIG Isocitrate dehydrogenase [NADP], mitochondrial precursor
            (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
            ICDH) (IDP) (ICD-M)
          Length = 421

 Score =  653 bits (1685), Expect = 0.0
 Identities = 311/412 (75%), Positives = 350/412 (84%), Gaps = 1/412 (0%)
 Frame = +1

Query: 82   YSIQRIVVTNPVVELDGDEMTRIIWEKIKDRLVFPYVKVDCKYYDLGLPHRDNTNDQVTI 261
            Y+ QRI V  PVVE+DGDEMTRIIW+ IK++L+ P+V V  KY+DLGLP+RD TNDQVTI
Sbjct: 8    YADQRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTI 67

Query: 262  DSAEAILKYNVGIKCATITPDEERVKEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIP 441
            DSA A  KY+V +KCATITPDE RV+EFKLKKMW SPNGTIRNILGGTVFREPIICK IP
Sbjct: 68   DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIP 127

Query: 442  RLVEGWKEAIIIGRHAHGDQYKATDYVATKPGKLELVFTPSDNSAADRMTVFEFKKRGGV 621
            RLV GW + I IGRHAHGDQYKATD+V  + G  ++VFTP D S+A +  V+ F   GGV
Sbjct: 128  RLVPGWTKPITIGRHAHGDQYKATDFVVDRAGTFKIVFTPKDGSSAKQWEVYNFPA-GGV 186

Query: 622  GLAMYNTDESIEGFAHSCFQYALNKKWPLYMSTKNTILKRYDGRFKDIFQEIYDRQYKAE 801
            G+ MYNTDESI GFAHSCFQYA+ KKWPLYMSTKNTILK YDGRFKDIFQEI+++ YK +
Sbjct: 187  GMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTD 246

Query: 802  FDKLKIWYEHRLIDDMVAQALKSSGGFVWGCKNYDGDVQSDIVAQGYGSLGLMTSVLMCP 981
            FDK KIWYEHRLIDDMVAQ LKSSGGFVW CKNYDGDVQSDI+AQG+GSLGLMTSVL+CP
Sbjct: 247  FDKYKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCP 306

Query: 982  DGKTIEAEAAHGTVTRHYREHQKGKPTSTNPIASIFAWTRGLEHRGKLDNNQELIRYCHL 1161
            DGKTIEAEAAHGTVTRHYREHQKG+PTSTNPIASIFAWTRGLEHRGKLD NQ+LIR+   
Sbjct: 307  DGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQT 366

Query: 1162 MERACVDTVDSGKMTKDLAACIHGLKNVQPN-HYLVTMDFLDAIAENFESKL 1314
            +E+ CV+TV+SG MTKDLA CIHGL NV+ N H+L T DFLD I  N +  L
Sbjct: 367  LEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRAL 418

>sp|P48735|IDHP_HUMAN Isocitrate dehydrogenase [NADP], mitochondrial precursor
            (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
            ICDH) (IDP) (ICD-M)
          Length = 452

 Score =  650 bits (1678), Expect = 0.0
 Identities = 309/412 (75%), Positives = 349/412 (84%), Gaps = 1/412 (0%)
 Frame = +1

Query: 82   YSIQRIVVTNPVVELDGDEMTRIIWEKIKDRLVFPYVKVDCKYYDLGLPHRDNTNDQVTI 261
            Y+ +RI V  PVVE+DGDEMTRIIW+ IK++L+ P+V +  KY+DLGLP+RD T+DQVTI
Sbjct: 39   YADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTI 98

Query: 262  DSAEAILKYNVGIKCATITPDEERVKEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIP 441
            DSA A  KY+V +KCATITPDE RV+EFKLKKMW SPNGTIRNILGGTVFREPIICK IP
Sbjct: 99   DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIP 158

Query: 442  RLVEGWKEAIIIGRHAHGDQYKATDYVATKPGKLELVFTPSDNSAADRMTVFEFKKRGGV 621
            RLV GW + I IGRHAHGDQYKATD+VA + G  ++VFTP D S      V+ F   GGV
Sbjct: 159  RLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPA-GGV 217

Query: 622  GLAMYNTDESIEGFAHSCFQYALNKKWPLYMSTKNTILKRYDGRFKDIFQEIYDRQYKAE 801
            G+ MYNTDESI GFAHSCFQYA+ KKWPLYMSTKNTILK YDGRFKDIFQEI+D+ YK +
Sbjct: 218  GMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTD 277

Query: 802  FDKLKIWYEHRLIDDMVAQALKSSGGFVWGCKNYDGDVQSDIVAQGYGSLGLMTSVLMCP 981
            FDK KIWYEHRLIDDMVAQ LKSSGGFVW CKNYDGDVQSDI+AQG+GSLGLMTSVL+CP
Sbjct: 278  FDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCP 337

Query: 982  DGKTIEAEAAHGTVTRHYREHQKGKPTSTNPIASIFAWTRGLEHRGKLDNNQELIRYCHL 1161
            DGKTIEAEAAHGTVTRHYREHQKG+PTSTNPIASIFAWTRGLEHRGKLD NQ+LIR+  +
Sbjct: 338  DGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQM 397

Query: 1162 MERACVDTVDSGKMTKDLAACIHGLKNVQPN-HYLVTMDFLDAIAENFESKL 1314
            +E+ CV+TV+SG MTKDLA CIHGL NV+ N H+L T DFLD I  N +  L
Sbjct: 398  LEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRAL 449

>sp|Q04467|IDHP_BOVIN Isocitrate dehydrogenase [NADP], mitochondrial precursor
            (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
            ICDH) (IDP) (ICD-M)
          Length = 452

 Score =  647 bits (1668), Expect = 0.0
 Identities = 309/412 (75%), Positives = 346/412 (83%), Gaps = 1/412 (0%)
 Frame = +1

Query: 82   YSIQRIVVTNPVVELDGDEMTRIIWEKIKDRLVFPYVKVDCKYYDLGLPHRDNTNDQVTI 261
            Y+ +RI V  PVVE+DGDEMTRIIW+ IK++L+ P+V V  KY+DLGLP+RD TNDQVTI
Sbjct: 39   YADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTI 98

Query: 262  DSAEAILKYNVGIKCATITPDEERVKEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIP 441
            DSA A  KY+V +KCATITPDE RV+EFKLKKMW SPNGTIRNILGGTVFREPIICK IP
Sbjct: 99   DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIP 158

Query: 442  RLVEGWKEAIIIGRHAHGDQYKATDYVATKPGKLELVFTPSDNSAADRMTVFEFKKRGGV 621
            RLV GW + I IGRHAHGDQYKATD+V  + G  ++VFTP D S      V+ F   GGV
Sbjct: 159  RLVPGWTKPITIGRHAHGDQYKATDFVVDRAGTFKVVFTPKDGSGPKEWEVYNFPA-GGV 217

Query: 622  GLAMYNTDESIEGFAHSCFQYALNKKWPLYMSTKNTILKRYDGRFKDIFQEIYDRQYKAE 801
            G+ MYNTDESI GFAHSCFQYA+ KKWPLYMSTKNTILK YDGRFKDIFQ I+++ YK E
Sbjct: 218  GMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTE 277

Query: 802  FDKLKIWYEHRLIDDMVAQALKSSGGFVWGCKNYDGDVQSDIVAQGYGSLGLMTSVLMCP 981
            FDK KIWYEHRLIDDMVAQ LKSSGGFVW CKNYDGDVQSDI+AQG+GSLGLMTSVL+CP
Sbjct: 278  FDKHKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCP 337

Query: 982  DGKTIEAEAAHGTVTRHYREHQKGKPTSTNPIASIFAWTRGLEHRGKLDNNQELIRYCHL 1161
            DGKTIEAEAAHGTVTRHYREHQKG+PTSTNPIASIFAWTRGLEHRGKLD NQ+LIR+   
Sbjct: 338  DGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQT 397

Query: 1162 MERACVDTVDSGKMTKDLAACIHGLKNVQPN-HYLVTMDFLDAIAENFESKL 1314
            +E+ CV+TV+SG MTKDLA CIHGL NV+ N H+L T DFLD I  N +  L
Sbjct: 398  LEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRAL 449

>sp|P54071|IDHP_MOUSE Isocitrate dehydrogenase [NADP], mitochondrial precursor
            (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
            ICDH) (IDP) (ICD-M)
          Length = 523

 Score =  624 bits (1610), Expect = e-178
 Identities = 301/412 (73%), Positives = 341/412 (82%), Gaps = 1/412 (0%)
 Frame = +1

Query: 82   YSIQRIVVTNPVVELDGDEMTRIIWEKIKDRLVFPYVKVDCKYYDLGLPHRDNTNDQVTI 261
            Y+ +RI V  PVVE+DGDEMTRIIW+ IK++L+ P+V V  KY+DLGLP+RD TNDQVTI
Sbjct: 111  YAEKRIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTI 170

Query: 262  DSAEAILKYNVGIKCATITPDEERVKEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIP 441
            DSA A  KY++ +KCATITPDE RV+EFKLKKMW SPNGTIRNILGGTVFREP ICK IP
Sbjct: 171  DSALAAQKYSMAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPSICKNIP 230

Query: 442  RLVEGWKEAIIIGRHAHGDQYKATDYVATKPGKLELVFTPSDNSAADRMTVFEFKKRGGV 621
            RLV GW + I IGRHAHGDQYKATD+V  + G  +LVFTP + S+A    V+ F   GGV
Sbjct: 231  RLVPGWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKNGSSAKEWEVYNFPG-GGV 289

Query: 622  GLAMYNTDESIEGFAHSCFQYALNKKWPLYMSTKNTILKRYDGRFKDIFQEIYDRQYKAE 801
            G+ MYNTDESI GFAHSCFQY++ KKWPLY+STKNTILK YDGRFKDIFQEI+D+ YK +
Sbjct: 290  GMGMYNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTD 349

Query: 802  FDKLKIWYEHRLIDDMVAQALKSSGGFVWGCKNYDGDVQSDIVAQGYGSLGLMTSVLMCP 981
            FD+ KIWYEHRLIDDMVAQ LKSSGGFVW CKNYDGDVQSDI+A  +GSLGLMTSVL+CP
Sbjct: 350  FDRNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILASRFGSLGLMTSVLVCP 409

Query: 982  DGKTIEAEAAHGTVTRHYREHQKGKPTSTNPIASIFAWTRGLEHRGKLDNNQELIRYCHL 1161
            DGKTIEAEAAHGTVTRHYREHQKG+PTST  IASIFAWTRGLEHRGKLD NQ+LIR+   
Sbjct: 410  DGKTIEAEAAHGTVTRHYREHQKGRPTSTKGIASIFAWTRGLEHRGKLDGNQDLIRFAQT 469

Query: 1162 MERACVDTVDSGKMTKDLAACIHGLKNVQPN-HYLVTMDFLDAIAENFESKL 1314
             E+ CV TV+ G MTKDLA CIHGL NV+ N H+L T DFLD I  N +  L
Sbjct: 470  REKVCVQTVE-GAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRAL 520

>sp|Q9Z2K9|IDHC_MICME Isocitrate dehydrogenase [NADP] cytoplasmic (Oxalosuccinate
            decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
          Length = 414

 Score =  605 bits (1559), Expect = e-172
 Identities = 284/400 (71%), Positives = 335/400 (83%)
 Frame = +1

Query: 115  VVELDGDEMTRIIWEKIKDRLVFPYVKVDCKYYDLGLPHRDNTNDQVTIDSAEAILKYNV 294
            VVE+ GDEMTRIIWE IK++L+ PYV++D   YDLG+ +RD TNDQVT D+AEAI KYNV
Sbjct: 10   VVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNV 69

Query: 295  GIKCATITPDEERVKEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIPRLVEGWKEAII 474
            G+KCATITPDE+RV+EFKLK+MW SPNGTIRNILGGTVFRE IICK IPRLV GW + II
Sbjct: 70   GVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPII 129

Query: 475  IGRHAHGDQYKATDYVATKPGKLELVFTPSDNSAADRMTVFEFKKRGGVGLAMYNTDESI 654
            IGRHA+GDQY+ATD+V   PGK+E+ FTP D S      V  F++ GGV + MYN D+SI
Sbjct: 130  IGRHAYGDQYRATDFVVPGPGKVEITFTPKDGSQKVTYLVHSFEEGGGVAMGMYNQDKSI 189

Query: 655  EGFAHSCFQYALNKKWPLYMSTKNTILKRYDGRFKDIFQEIYDRQYKAEFDKLKIWYEHR 834
            E FAHS FQ AL+K WPLY+STKNTILK+YDGRFKDIFQEIYD+QYK++F+  KIWYEHR
Sbjct: 190  EDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHR 249

Query: 835  LIDDMVAQALKSSGGFVWGCKNYDGDVQSDIVAQGYGSLGLMTSVLMCPDGKTIEAEAAH 1014
            LIDDMVAQA+KS GGF+W CKNYDGDVQSD VAQGYGSLG+MTSVL+CPDGKT+EAEAAH
Sbjct: 250  LIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAH 309

Query: 1015 GTVTRHYREHQKGKPTSTNPIASIFAWTRGLEHRGKLDNNQELIRYCHLMERACVDTVDS 1194
            GTVTRHYR HQKG+ TSTNPIASIFAW+RGL HR +LDNN EL  +   +E  C++T+++
Sbjct: 310  GTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALEEVCIETIEA 369

Query: 1195 GKMTKDLAACIHGLKNVQPNHYLVTMDFLDAIAENFESKL 1314
            G MTKDLAACI GL NVQ + YL T +F+D + EN ++KL
Sbjct: 370  GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKL 409

>sp|P41562|IDHC_RAT Isocitrate dehydrogenase [NADP] cytoplasmic (Oxalosuccinate
            decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
          Length = 414

 Score =  603 bits (1556), Expect = e-172
 Identities = 283/400 (70%), Positives = 337/400 (84%)
 Frame = +1

Query: 115  VVELDGDEMTRIIWEKIKDRLVFPYVKVDCKYYDLGLPHRDNTNDQVTIDSAEAILKYNV 294
            VVE+ GDEMTRIIWE IK++L+ PYV++D   YDLG+ +RD TNDQVT D+AEAI KYNV
Sbjct: 10   VVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNV 69

Query: 295  GIKCATITPDEERVKEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIPRLVEGWKEAII 474
            G+KCATITPDE+RV+EFKLK+MW SPNGTIRNILGGTVFRE IICK IPRLV GW + II
Sbjct: 70   GVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPII 129

Query: 475  IGRHAHGDQYKATDYVATKPGKLELVFTPSDNSAADRMTVFEFKKRGGVGLAMYNTDESI 654
            IGRHA+GDQY+ATD+V   PGK+E+ +TP D S      V +F++ GGV + MYN D+SI
Sbjct: 130  IGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYLVHDFEEGGGVAMGMYNQDKSI 189

Query: 655  EGFAHSCFQYALNKKWPLYMSTKNTILKRYDGRFKDIFQEIYDRQYKAEFDKLKIWYEHR 834
            E FAHS FQ AL+K WPLY+STKNTILK+YDGRFKDIFQEIYD+QYK++F+  KIWYEHR
Sbjct: 190  EDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSKFEAQKIWYEHR 249

Query: 835  LIDDMVAQALKSSGGFVWGCKNYDGDVQSDIVAQGYGSLGLMTSVLMCPDGKTIEAEAAH 1014
            LIDDMVAQA+KS GGF+W CKNYDGDVQSD VAQGYGSLG+MTSVL+CPDGKT+EAEAAH
Sbjct: 250  LIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAH 309

Query: 1015 GTVTRHYREHQKGKPTSTNPIASIFAWTRGLEHRGKLDNNQELIRYCHLMERACVDTVDS 1194
            GTVTRHYR +QKG+ TSTNPIASIFAW+RGL HR KLDNN EL  + + +E  C++T+++
Sbjct: 310  GTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFANALEEVCIETIEA 369

Query: 1195 GKMTKDLAACIHGLKNVQPNHYLVTMDFLDAIAENFESKL 1314
            G MTKDLAACI GL NVQ + YL T +F+D + EN ++KL
Sbjct: 370  GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKL 409

>sp|Q9Z2K8|IDHC_MICOH Isocitrate dehydrogenase [NADP] cytoplasmic (Oxalosuccinate
            decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
          Length = 414

 Score =  603 bits (1556), Expect = e-172
 Identities = 283/400 (70%), Positives = 335/400 (83%)
 Frame = +1

Query: 115  VVELDGDEMTRIIWEKIKDRLVFPYVKVDCKYYDLGLPHRDNTNDQVTIDSAEAILKYNV 294
            VVE+ GDEMTRIIWE IK++L+ PYV++D   YDLG+ +RD TNDQVT D+AEAI KYNV
Sbjct: 10   VVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNV 69

Query: 295  GIKCATITPDEERVKEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIPRLVEGWKEAII 474
            G+KCATITPDE+RV+EFKLK+MW SPNGTIRNILGGTVFRE IICK IPRLV GW + II
Sbjct: 70   GVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPII 129

Query: 475  IGRHAHGDQYKATDYVATKPGKLELVFTPSDNSAADRMTVFEFKKRGGVGLAMYNTDESI 654
            IGRHA+GDQY+ATD+V   PGK+E+ +TP D S      V  F++ GGV + MYN D+SI
Sbjct: 130  IGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYLVHSFEEGGGVAMGMYNQDKSI 189

Query: 655  EGFAHSCFQYALNKKWPLYMSTKNTILKRYDGRFKDIFQEIYDRQYKAEFDKLKIWYEHR 834
            E FAHS FQ AL+K WPLY+STKNTILK+YDGRFKDIFQEIYD+QYK++F+  KIWYEHR
Sbjct: 190  EDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHR 249

Query: 835  LIDDMVAQALKSSGGFVWGCKNYDGDVQSDIVAQGYGSLGLMTSVLMCPDGKTIEAEAAH 1014
            LIDDMVAQA+KS GGF+W CKNYDGDVQSD VAQGYGSLG+MTSVL+CPDGKT+EAEAAH
Sbjct: 250  LIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAH 309

Query: 1015 GTVTRHYREHQKGKPTSTNPIASIFAWTRGLEHRGKLDNNQELIRYCHLMERACVDTVDS 1194
            GTVTRHYR HQKG+ TSTNPIASIFAW+RGL HR +LDNN EL  +   +E  C++T+++
Sbjct: 310  GTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALEEVCIETIEA 369

Query: 1195 GKMTKDLAACIHGLKNVQPNHYLVTMDFLDAIAENFESKL 1314
            G MTKDLAACI GL NVQ + YL T +F+D + EN ++KL
Sbjct: 370  GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKL 409

>sp|O75874|IDHC_HUMAN Isocitrate dehydrogenase [NADP] cytoplasmic (Oxalosuccinate
            decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
          Length = 414

 Score =  602 bits (1552), Expect = e-172
 Identities = 283/400 (70%), Positives = 337/400 (84%)
 Frame = +1

Query: 115  VVELDGDEMTRIIWEKIKDRLVFPYVKVDCKYYDLGLPHRDNTNDQVTIDSAEAILKYNV 294
            VVE+ GDEMTRIIWE IK++L+FPYV++D   YDLG+ +RD TNDQVT D+AEAI K+NV
Sbjct: 10   VVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNV 69

Query: 295  GIKCATITPDEERVKEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIPRLVEGWKEAII 474
            G+KCATITPDE+RV+EFKLK+MW SPNGTIRNILGGTVFRE IICK IPRLV GW + II
Sbjct: 70   GVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPII 129

Query: 475  IGRHAHGDQYKATDYVATKPGKLELVFTPSDNSAADRMTVFEFKKRGGVGLAMYNTDESI 654
            IGRHA+GDQY+ATD+V   PGK+E+ +TPSD +      V  F++ GGV + MYN D+SI
Sbjct: 130  IGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSI 189

Query: 655  EGFAHSCFQYALNKKWPLYMSTKNTILKRYDGRFKDIFQEIYDRQYKAEFDKLKIWYEHR 834
            E FAHS FQ AL+K WPLY+STKNTILK+YDGRFKDIFQEIYD+QYK++F+  KIWYEHR
Sbjct: 190  EDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHR 249

Query: 835  LIDDMVAQALKSSGGFVWGCKNYDGDVQSDIVAQGYGSLGLMTSVLMCPDGKTIEAEAAH 1014
            LIDDMVAQA+KS GGF+W CKNYDGDVQSD VAQGYGSLG+MTSVL+CPDGKT+EAEAAH
Sbjct: 250  LIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAH 309

Query: 1015 GTVTRHYREHQKGKPTSTNPIASIFAWTRGLEHRGKLDNNQELIRYCHLMERACVDTVDS 1194
            GTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLDNN+EL  + + +E   ++T+++
Sbjct: 310  GTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEA 369

Query: 1195 GKMTKDLAACIHGLKNVQPNHYLVTMDFLDAIAENFESKL 1314
            G MTKDLAACI GL NVQ + YL T +F+D + EN + KL
Sbjct: 370  GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKL 409

>sp|O88844|IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytoplasmic (Oxalosuccinate
            decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
          Length = 414

 Score =  593 bits (1529), Expect = e-169
 Identities = 280/409 (68%), Positives = 337/409 (82%)
 Frame = +1

Query: 88   IQRIVVTNPVVELDGDEMTRIIWEKIKDRLVFPYVKVDCKYYDLGLPHRDNTNDQVTIDS 267
            + R +    VVE+ GDEMTRIIWE IK++L+ PYV++D   YDLG+ +RD TNDQVT D+
Sbjct: 1    MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60

Query: 268  AEAILKYNVGIKCATITPDEERVKEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIPRL 447
            AEAI KYNVG+KCATITPDE+RV+EFKLK+MW SPNGTIRNILGGTVFRE IICK IPRL
Sbjct: 61   AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120

Query: 448  VEGWKEAIIIGRHAHGDQYKATDYVATKPGKLELVFTPSDNSAADRMTVFEFKKRGGVGL 627
            V GW + IIIGRHA+GDQY+ATD+V   PGK+E+ +TP D +      V +F++ GGV +
Sbjct: 121  VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180

Query: 628  AMYNTDESIEGFAHSCFQYALNKKWPLYMSTKNTILKRYDGRFKDIFQEIYDRQYKAEFD 807
             MYN D+SIE FAHS FQ AL+K WPLY+STKNTILK+YDGRFKDIFQEIYD++YK++F+
Sbjct: 181  GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240

Query: 808  KLKIWYEHRLIDDMVAQALKSSGGFVWGCKNYDGDVQSDIVAQGYGSLGLMTSVLMCPDG 987
               I YEHRLIDDMVAQA+KS GGF+W CKNYDGDVQSD VAQGYGSLG+MTSVL+CPDG
Sbjct: 241  AQNICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300

Query: 988  KTIEAEAAHGTVTRHYREHQKGKPTSTNPIASIFAWTRGLEHRGKLDNNQELIRYCHLME 1167
            KT+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAW+RGL HR KLDNN EL  +   +E
Sbjct: 301  KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360

Query: 1168 RACVDTVDSGKMTKDLAACIHGLKNVQPNHYLVTMDFLDAIAENFESKL 1314
              C++T+++G MTKDLAACI GL NVQ + YL T +F+D + EN ++KL
Sbjct: 361  DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKL 409

>sp|Q40345|IDHP_MEDSA Isocitrate dehydrogenase [NADP], chloroplast precursor
            (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
            ICDH) (IDP)
          Length = 433

 Score =  586 bits (1511), Expect = e-167
 Identities = 279/410 (68%), Positives = 328/410 (80%)
 Frame = +1

Query: 91   QRIVVTNPVVELDGDEMTRIIWEKIKDRLVFPYVKVDCKYYDLGLPHRDNTNDQVTIDSA 270
            Q+I V NP+VE+DGDEMTRIIW+ IKD+L+FP+V++D KY+DLGLP+RD TND+VT++SA
Sbjct: 25   QKIKVANPIVEMDGDEMTRIIWKYIKDKLIFPFVELDIKYFDLGLPYRDETNDKVTVESA 84

Query: 271  EAILKYNVGIKCATITPDEERVKEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIPRLV 450
            EA LKYNV IKCATITPDE RVKEF LK MW SPNGTIRNIL GTVFREPIICK IPRL+
Sbjct: 85   EATLKYNVAIKCATITPDEARVKEFGLKSMWRSPNGTIRNILNGTVFREPIICKNIPRLI 144

Query: 451  EGWKEAIIIGRHAHGDQYKATDYVATKPGKLELVFTPSDNSAADRMTVFEFKKRGGVGLA 630
             GW + I IGRHA GDQY+ATD V   PGKL+LVF P        + V+ F   GGV LA
Sbjct: 145  PGWTKPICIGRHAFGDQYRATDSVIKGPGKLKLVFVPEGQGETTDLEVYNFTGEGGVALA 204

Query: 631  MYNTDESIEGFAHSCFQYALNKKWPLYMSTKNTILKRYDGRFKDIFQEIYDRQYKAEFDK 810
            MYNTDESI  FA +    AL KKWPLY+STKNTILK+YDGRFKDIFQE+Y+  +K++++ 
Sbjct: 205  MYNTDESIRSFAEASMAVALEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEAGWKSKYEA 264

Query: 811  LKIWYEHRLIDDMVAQALKSSGGFVWGCKNYDGDVQSDIVAQGYGSLGLMTSVLMCPDGK 990
              IWYEHRLIDDMVA ALKS GG+VW CKNYDGDVQSD +AQG+GSLGLMTSVL+CPDGK
Sbjct: 265  AGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGK 324

Query: 991  TIEAEAAHGTVTRHYREHQKGKPTSTNPIASIFAWTRGLEHRGKLDNNQELIRYCHLMER 1170
            TIEAEAAHGTVTRH+R HQKG  TSTN IASIFAWTRGL HR KLD+N  L+ +   +E 
Sbjct: 325  TIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNATLLDFTEKLEA 384

Query: 1171 ACVDTVDSGKMTKDLAACIHGLKNVQPNHYLVTMDFLDAIAENFESKLKA 1320
            AC+  V+SGKMTKDLA  +HG K +   HYL T +F+DA+A   ++K+ A
Sbjct: 385  ACIGVVESGKMTKDLALILHGSK-LSREHYLNTEEFIDAVAAELKTKISA 433

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 173,010,078
Number of Sequences: 369166
Number of extensions: 3801926
Number of successful extensions: 9682
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 9089
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9648
length of database: 68,354,980
effective HSP length: 114
effective length of database: 47,295,190
effective search space used: 17026268400
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00212

  1. Dr_sW_006_D19
  2. Dr_sW_001_F01
  3. Dr_sW_012_L22
  4. Dr_sW_028_A13
  5. Dr_sW_020_M20
  6. Dr_sW_013_O12
  7. Dr_sW_004_G18