Planaria EST Database


DrC_00589

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00589
         (527 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q14019|COTL1_HUMAN  Coactosin-like protein                     129   6e-30
sp|Q9CQI6|COTL1_MOUSE  Coactosin-like protein                     126   3e-29
sp|P34121|COAC_DICDI  Coactosin (Cytoskeletal p17 protein) (...    93   5e-19
sp|Q9P7E8|APP1_SCHPO  Protein app1                                 51   2e-06
sp|Q62418|DBNL_MOUSE  Drebrin-like protein (SH3 domain-conta...    49   1e-05
sp|Q9JHL4|DBNL_RAT  Drebrin-like protein (SH3 domain-contain...    47   2e-05
sp|Q9UJU6|DBNL_HUMAN  Drebrin-like protein (SH3 domain-conta...    47   3e-05
sp|Q07266|DREB_RAT  Drebrin (Developmentally regulated brain...    33   0.55 
sp|Q16643|DREB_HUMAN  Drebrin (Developmentally regulated bra...    33   0.55 
sp|Q9QXS6|DREB_MOUSE  Drebrin (Developmentally regulated bra...    33   0.55 
>sp|Q14019|COTL1_HUMAN Coactosin-like protein
          Length = 142

 Score =  129 bits (323), Expect = 6e-30
 Identities = 66/137 (48%), Positives = 88/137 (64%)
 Frame = +1

Query: 16  MTSKIDKETISEAYEDVRNDATETTWALFGYDDKKIVVVKTGTLYESLLAEFNDDERHFA 195
           M +KIDKE    AY  VR+D +   W  F YD   IV  + G  Y+  + +  DD R FA
Sbjct: 1   MATKIDKEACRAAYNLVRDDGSAVIWVTFKYDGSTIVPGEQGAEYQHFIQQCTDDVRLFA 60

Query: 196 FVRMITGDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEI 375
           FVR  TGD MSKR+KFALIT+ G NVS +++A    DK+LVKEVV ++A +   SD+ E+
Sbjct: 61  FVRFTTGDAMSKRSKFALITWIGENVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKEL 120

Query: 376 TESKLRAALEKAGGANY 426
            E  +++ L+KAGGANY
Sbjct: 121 EEDFIKSELKKAGGANY 137
>sp|Q9CQI6|COTL1_MOUSE Coactosin-like protein
          Length = 142

 Score =  126 bits (317), Expect = 3e-29
 Identities = 66/137 (48%), Positives = 87/137 (63%)
 Frame = +1

Query: 16  MTSKIDKETISEAYEDVRNDATETTWALFGYDDKKIVVVKTGTLYESLLAEFNDDERHFA 195
           M +KIDKE    AY  VR+D +   W  F YD   IV    G  Y+  + +  DD R FA
Sbjct: 1   MATKIDKEACRAAYNLVRDDGSAVIWVTFRYDGATIVPGDQGADYQHFIQQCTDDVRLFA 60

Query: 196 FVRMITGDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEI 375
           FVR  TGD MSKR+KFALIT+ G +VS +++A    DK+LVKEVV ++A +   SD+ E+
Sbjct: 61  FVRFTTGDAMSKRSKFALITWIGEDVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKEL 120

Query: 376 TESKLRAALEKAGGANY 426
            E  +R+ L+KAGGANY
Sbjct: 121 EEDFIRSELKKAGGANY 137
>sp|P34121|COAC_DICDI Coactosin (Cytoskeletal p17 protein) (Cyclic AMP-regulated protein
           p16)
          Length = 146

 Score = 92.8 bits (229), Expect = 5e-19
 Identities = 47/142 (33%), Positives = 84/142 (59%), Gaps = 3/142 (2%)
 Frame = +1

Query: 28  IDKETISEAYEDVRNDATETTWALFGYDDKKIVVV--KTGTLYESLLAEFND-DERHFAF 198
           +    +  AY++V  D+ +T W LF Y+ K  +V+  K    +  L  E N   ER +A+
Sbjct: 4   VSSTELKAAYDEVLADSNDTNWCLFKYEGKNKIVLSGKGSGGFAELAQEINQPSERLYAY 63

Query: 199 VRMITGDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEIT 378
           +R+++GD+ SKR+KF  I++CG  V  + KAN++V K+ VK+V+ +  V++  +  +++ 
Sbjct: 64  LRVVSGDDESKRSKFVFISWCGEEVGPLAKANVSVHKASVKQVIKNIGVEVHYTVADDLN 123

Query: 379 ESKLRAALEKAGGANYGSAK*T 444
           E +L   + K+ GA+Y   K T
Sbjct: 124 EEELMTKVRKSSGADYSGNKST 145
>sp|Q9P7E8|APP1_SCHPO Protein app1
          Length = 857

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 35/144 (24%), Positives = 70/144 (48%), Gaps = 7/144 (4%)
 Frame = +1

Query: 16  MTSKIDKET----ISEAYEDVRNDATETTWALFGYDDKK---IVVVKTGTLYESLLAEFN 174
           M+ ++D  T    I   YE V + A + +WA+FGY+  +   + VV +G   +  L EF+
Sbjct: 1   MSFQLDTSTHGAEIRNVYEKVLSGADDCSWAIFGYEKGQGNILKVVASGNDNDEFLDEFD 60

Query: 175 DDERHFAFVRMITGDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLF 354
           ++   F F+R+   D  +   KF L+ +CG   +  +K   ++  + V  ++  Y V + 
Sbjct: 61  ENAVLFGFLRV--KDVNTGLNKFVLVCWCGE--AAARKGLFSIHMATVSNLLKGYHVQIT 116

Query: 355 TSDKNEITESKLRAALEKAGGANY 426
             + +++    +   +  A G+ Y
Sbjct: 117 GRESSDLNMDDIIRRVADASGSKY 140
>sp|Q62418|DBNL_MOUSE Drebrin-like protein (SH3 domain-containing protein 7)
           (Actin-binding protein 1)
          Length = 436

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 38/139 (27%), Positives = 61/139 (43%), Gaps = 3/139 (2%)
 Frame = +1

Query: 43  ISEAYEDVRNDATETTWALFGYDDKKIVVVKTGT---LYESLLAEFNDDERHFAFVRMIT 213
           + EAY  V  + + T WALF Y+     +   GT     E L+ E N  +  +AF R+  
Sbjct: 12  LQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEELVEELNSGKVMYAFCRV-- 69

Query: 214 GDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEITESKLR 393
            D  S   KF LI + G  V+ ++K       S +   +    V +    + ++    + 
Sbjct: 70  KDPNSGLPKFVLINWTGEGVNDVRKGACANHVSTMANFLKGAHVTINARAEEDVEPECIM 129

Query: 394 AALEKAGGANYGSAK*TTN 450
             + KA GANY   K +T+
Sbjct: 130 EKVAKASGANYSFHKESTS 148
>sp|Q9JHL4|DBNL_RAT Drebrin-like protein (SH3 domain-containing protein 7)
          Length = 436

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 3/135 (2%)
 Frame = +1

Query: 43  ISEAYEDVRNDATETTWALFGYDDKKIVVVKTGT---LYESLLAEFNDDERHFAFVRMIT 213
           + EAY  V  + + T WALF Y+     +   GT     E L+ E N  +  +AF R+  
Sbjct: 12  LQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEELVEELNSGKVMYAFCRV-- 69

Query: 214 GDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEITESKLR 393
            D  S   KF LI + G  V+ ++K       S +   +    V +    + ++    + 
Sbjct: 70  KDPNSGLPKFVLINWTGEGVNDVRKGACANHVSTMANFLKGAHVTINARAEEDVEPECIM 129

Query: 394 AALEKAGGANYGSAK 438
             + KA GANY   K
Sbjct: 130 EKVAKASGANYSFHK 144
>sp|Q9UJU6|DBNL_HUMAN Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F)
           (Cervical SH3P7) (HPK1-interacting protein of 55 kDa)
           (HIP-55) (Cervical mucin-associated protein)
          Length = 430

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 3/135 (2%)
 Frame = +1

Query: 43  ISEAYEDVRNDATETTWALFGYDDKKIVVVKTGT---LYESLLAEFNDDERHFAFVRMIT 213
           + EAY  V  + + T WALF Y+     +   GT     E ++ E N  +  +AF R+  
Sbjct: 12  LQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEEMVEELNSGKVMYAFCRV-- 69

Query: 214 GDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEITESKLR 393
            D  S   KF LI + G  V+ ++K       S +   +    V +    + ++    + 
Sbjct: 70  KDPNSGLPKFVLINWTGEGVNDVRKGACASHVSTMASFLKGAHVTINARAEEDVEPECIM 129

Query: 394 AALEKAGGANYGSAK 438
             + KA GANY   K
Sbjct: 130 EKVAKASGANYSFHK 144
>sp|Q07266|DREB_RAT Drebrin (Developmentally regulated brain protein)
          Length = 707

 Score = 32.7 bits (73), Expect = 0.55
 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
 Frame = +1

Query: 52  AYEDVRNDATETTWALFGY----DDKKIVVVKTGTLYESLLAEFNDDERHFAFVRMITGD 219
           AYE+V  + +   WAL+ Y    DD K+     G L E L   F + +  + F  +   D
Sbjct: 16  AYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQE-LSGHFENQKVMYGFCSV--KD 72

Query: 220 EMSKRAKFALITYCGANVSVMKK 288
             +   K+ LI + G +V   +K
Sbjct: 73  SQAALPKYVLINWVGEDVPDARK 95
>sp|Q16643|DREB_HUMAN Drebrin (Developmentally regulated brain protein)
          Length = 649

 Score = 32.7 bits (73), Expect = 0.55
 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
 Frame = +1

Query: 52  AYEDVRNDATETTWALFGY----DDKKIVVVKTGTLYESLLAEFNDDERHFAFVRMITGD 219
           AYE+V  + +   WAL+ Y    DD K+     G L E L   F + +  + F  +   D
Sbjct: 16  AYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQE-LSGHFENQKVMYGFCSV--KD 72

Query: 220 EMSKRAKFALITYCGANVSVMKK 288
             +   K+ LI + G +V   +K
Sbjct: 73  SQAALPKYVLINWVGEDVPDARK 95
>sp|Q9QXS6|DREB_MOUSE Drebrin (Developmentally regulated brain protein)
          Length = 706

 Score = 32.7 bits (73), Expect = 0.55
 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
 Frame = +1

Query: 52  AYEDVRNDATETTWALFGY----DDKKIVVVKTGTLYESLLAEFNDDERHFAFVRMITGD 219
           AYE+V  + +   WAL+ Y    DD K+     G L E L   F + +  + F  +   D
Sbjct: 16  AYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQE-LSGHFENQKVMYGFCSV--KD 72

Query: 220 EMSKRAKFALITYCGANVSVMKK 288
             +   K+ LI + G +V   +K
Sbjct: 73  SQAALPKYVLINWVGEDVPDARK 95
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,334,084
Number of Sequences: 369166
Number of extensions: 721120
Number of successful extensions: 2126
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2103
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2125
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3551563800
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00589

  1. Dr_sW_028_O04
  2. Dr_sW_015_G17
  3. Dr_sW_026_G04
  4. Dr_sW_016_B03
  5. Dr_sW_016_F11
  6. Dr_sW_015_H21
  7. Dr_sW_014_A11
  8. Dr_sW_005_D22
  9. Dr_sW_018_I03
  10. Dr_sW_012_K18
  11. Dr_sW_001_C13