Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_026_G04 (475 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q14019|COTL1_HUMAN Coactosin-like protein 127 2e-29 sp|Q9CQI6|COTL1_MOUSE Coactosin-like protein 124 8e-29 sp|P34121|COAC_DICDI Coactosin (Cytoskeletal p17 protein) (... 93 4e-19 sp|Q9P7E8|APP1_SCHPO Protein app1 50 2e-06 sp|Q62418|DBNL_MOUSE Drebrin-like protein (SH3 domain-conta... 49 8e-06 sp|Q9JHL4|DBNL_RAT Drebrin-like protein (SH3 domain-contain... 47 2e-05 sp|Q9UJU6|DBNL_HUMAN Drebrin-like protein (SH3 domain-conta... 47 2e-05 sp|Q07266|DREB_RAT Drebrin (Developmentally regulated brain... 33 0.43 sp|Q16643|DREB_HUMAN Drebrin (Developmentally regulated bra... 33 0.43 sp|Q9QXS6|DREB_MOUSE Drebrin (Developmentally regulated bra... 33 0.43
>sp|Q14019|COTL1_HUMAN Coactosin-like protein Length = 142 Score = 127 bits (318), Expect = 2e-29 Identities = 65/135 (48%), Positives = 87/135 (64%) Frame = +1 Query: 1 SKIDKETISEAYEDVRNDATETTWALFGYDDKKIVVVKTGTLYESLLAEFNDDERHFAFV 180 +KIDKE AY VR+D + W F YD IV + G Y+ + + DD R FAFV Sbjct: 3 TKIDKEACRAAYNLVRDDGSAVIWVTFKYDGSTIVPGEQGAEYQHFIQQCTDDVRLFAFV 62 Query: 181 RMITGDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEITE 360 R TGD MSKR+KFALIT+ G NVS +++A DK+LVKEVV ++A + SD+ E+ E Sbjct: 63 RFTTGDAMSKRSKFALITWIGENVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKELEE 122 Query: 361 SKLRAALEKAGGANY 405 +++ L+KAGGANY Sbjct: 123 DFIKSELKKAGGANY 137
>sp|Q9CQI6|COTL1_MOUSE Coactosin-like protein Length = 142 Score = 124 bits (312), Expect = 8e-29 Identities = 65/135 (48%), Positives = 86/135 (63%) Frame = +1 Query: 1 SKIDKETISEAYEDVRNDATETTWALFGYDDKKIVVVKTGTLYESLLAEFNDDERHFAFV 180 +KIDKE AY VR+D + W F YD IV G Y+ + + DD R FAFV Sbjct: 3 TKIDKEACRAAYNLVRDDGSAVIWVTFRYDGATIVPGDQGADYQHFIQQCTDDVRLFAFV 62 Query: 181 RMITGDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEITE 360 R TGD MSKR+KFALIT+ G +VS +++A DK+LVKEVV ++A + SD+ E+ E Sbjct: 63 RFTTGDAMSKRSKFALITWIGEDVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKELEE 122 Query: 361 SKLRAALEKAGGANY 405 +R+ L+KAGGANY Sbjct: 123 DFIRSELKKAGGANY 137
>sp|P34121|COAC_DICDI Coactosin (Cytoskeletal p17 protein) (Cyclic AMP-regulated protein p16) Length = 146 Score = 92.8 bits (229), Expect = 4e-19 Identities = 47/142 (33%), Positives = 84/142 (59%), Gaps = 3/142 (2%) Frame = +1 Query: 7 IDKETISEAYEDVRNDATETTWALFGYDDKKIVVV--KTGTLYESLLAEFND-DERHFAF 177 + + AY++V D+ +T W LF Y+ K +V+ K + L E N ER +A+ Sbjct: 4 VSSTELKAAYDEVLADSNDTNWCLFKYEGKNKIVLSGKGSGGFAELAQEINQPSERLYAY 63 Query: 178 VRMITGDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEIT 357 +R+++GD+ SKR+KF I++CG V + KAN++V K+ VK+V+ + V++ + +++ Sbjct: 64 LRVVSGDDESKRSKFVFISWCGEEVGPLAKANVSVHKASVKQVIKNIGVEVHYTVADDLN 123 Query: 358 ESKLRAALEKAGGANYGSAK*T 423 E +L + K+ GA+Y K T Sbjct: 124 EEELMTKVRKSSGADYSGNKST 145
>sp|Q9P7E8|APP1_SCHPO Protein app1 Length = 857 Score = 50.4 bits (119), Expect = 2e-06 Identities = 32/131 (24%), Positives = 64/131 (48%), Gaps = 3/131 (2%) Frame = +1 Query: 22 ISEAYEDVRNDATETTWALFGYDDKK---IVVVKTGTLYESLLAEFNDDERHFAFVRMIT 192 I YE V + A + +WA+FGY+ + + VV +G + L EF+++ F F+R+ Sbjct: 14 IRNVYEKVLSGADDCSWAIFGYEKGQGNILKVVASGNDNDEFLDEFDENAVLFGFLRV-- 71 Query: 193 GDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEITESKLR 372 D + KF L+ +CG + +K ++ + V ++ Y V + + +++ + Sbjct: 72 KDVNTGLNKFVLVCWCGE--AAARKGLFSIHMATVSNLLKGYHVQITGRESSDLNMDDII 129 Query: 373 AALEKAGGANY 405 + A G+ Y Sbjct: 130 RRVADASGSKY 140
>sp|Q62418|DBNL_MOUSE Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1) Length = 436 Score = 48.5 bits (114), Expect = 8e-06 Identities = 38/139 (27%), Positives = 61/139 (43%), Gaps = 3/139 (2%) Frame = +1 Query: 22 ISEAYEDVRNDATETTWALFGYDDKKIVVVKTGT---LYESLLAEFNDDERHFAFVRMIT 192 + EAY V + + T WALF Y+ + GT E L+ E N + +AF R+ Sbjct: 12 LQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEELVEELNSGKVMYAFCRV-- 69 Query: 193 GDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEITESKLR 372 D S KF LI + G V+ ++K S + + V + + ++ + Sbjct: 70 KDPNSGLPKFVLINWTGEGVNDVRKGACANHVSTMANFLKGAHVTINARAEEDVEPECIM 129 Query: 373 AALEKAGGANYGSAK*TTN 429 + KA GANY K +T+ Sbjct: 130 EKVAKASGANYSFHKESTS 148
>sp|Q9JHL4|DBNL_RAT Drebrin-like protein (SH3 domain-containing protein 7) Length = 436 Score = 47.4 bits (111), Expect = 2e-05 Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 3/135 (2%) Frame = +1 Query: 22 ISEAYEDVRNDATETTWALFGYDDKKIVVVKTGT---LYESLLAEFNDDERHFAFVRMIT 192 + EAY V + + T WALF Y+ + GT E L+ E N + +AF R+ Sbjct: 12 LQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEELVEELNSGKVMYAFCRV-- 69 Query: 193 GDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEITESKLR 372 D S KF LI + G V+ ++K S + + V + + ++ + Sbjct: 70 KDPNSGLPKFVLINWTGEGVNDVRKGACANHVSTMANFLKGAHVTINARAEEDVEPECIM 129 Query: 373 AALEKAGGANYGSAK 417 + KA GANY K Sbjct: 130 EKVAKASGANYSFHK 144
>sp|Q9UJU6|DBNL_HUMAN Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein) Length = 430 Score = 47.0 bits (110), Expect = 2e-05 Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 3/135 (2%) Frame = +1 Query: 22 ISEAYEDVRNDATETTWALFGYDDKKIVVVKTGT---LYESLLAEFNDDERHFAFVRMIT 192 + EAY V + + T WALF Y+ + GT E ++ E N + +AF R+ Sbjct: 12 LQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEEMVEELNSGKVMYAFCRV-- 69 Query: 193 GDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEITESKLR 372 D S KF LI + G V+ ++K S + + V + + ++ + Sbjct: 70 KDPNSGLPKFVLINWTGEGVNDVRKGACASHVSTMASFLKGAHVTINARAEEDVEPECIM 129 Query: 373 AALEKAGGANYGSAK 417 + KA GANY K Sbjct: 130 EKVAKASGANYSFHK 144
>sp|Q07266|DREB_RAT Drebrin (Developmentally regulated brain protein) Length = 707 Score = 32.7 bits (73), Expect = 0.43 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 4/83 (4%) Frame = +1 Query: 31 AYEDVRNDATETTWALFGY----DDKKIVVVKTGTLYESLLAEFNDDERHFAFVRMITGD 198 AYE+V + + WAL+ Y DD K+ G L E L F + + + F + D Sbjct: 16 AYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQE-LSGHFENQKVMYGFCSV--KD 72 Query: 199 EMSKRAKFALITYCGANVSVMKK 267 + K+ LI + G +V +K Sbjct: 73 SQAALPKYVLINWVGEDVPDARK 95
>sp|Q16643|DREB_HUMAN Drebrin (Developmentally regulated brain protein) Length = 649 Score = 32.7 bits (73), Expect = 0.43 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 4/83 (4%) Frame = +1 Query: 31 AYEDVRNDATETTWALFGY----DDKKIVVVKTGTLYESLLAEFNDDERHFAFVRMITGD 198 AYE+V + + WAL+ Y DD K+ G L E L F + + + F + D Sbjct: 16 AYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQE-LSGHFENQKVMYGFCSV--KD 72 Query: 199 EMSKRAKFALITYCGANVSVMKK 267 + K+ LI + G +V +K Sbjct: 73 SQAALPKYVLINWVGEDVPDARK 95
>sp|Q9QXS6|DREB_MOUSE Drebrin (Developmentally regulated brain protein) Length = 706 Score = 32.7 bits (73), Expect = 0.43 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 4/83 (4%) Frame = +1 Query: 31 AYEDVRNDATETTWALFGY----DDKKIVVVKTGTLYESLLAEFNDDERHFAFVRMITGD 198 AYE+V + + WAL+ Y DD K+ G L E L F + + + F + D Sbjct: 16 AYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQE-LSGHFENQKVMYGFCSV--KD 72 Query: 199 EMSKRAKFALITYCGANVSVMKK 267 + K+ LI + G +V +K Sbjct: 73 SQAALPKYVLINWVGEDVPDARK 95
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 41,537,507 Number of Sequences: 369166 Number of extensions: 641502 Number of successful extensions: 2011 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1989 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2010 length of database: 68,354,980 effective HSP length: 101 effective length of database: 49,696,745 effective search space used: 2783017720 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)