Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_B03
(502 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q14019|COTL1_HUMAN Coactosin-like protein 124 1e-28
sp|Q9CQI6|COTL1_MOUSE Coactosin-like protein 122 5e-28
sp|P34121|COAC_DICDI Coactosin (Cytoskeletal p17 protein) (... 93 4e-19
sp|Q9P7E8|APP1_SCHPO Protein app1 50 2e-06
sp|Q62418|DBNL_MOUSE Drebrin-like protein (SH3 domain-conta... 49 9e-06
sp|Q9JHL4|DBNL_RAT Drebrin-like protein (SH3 domain-contain... 47 2e-05
sp|Q9UJU6|DBNL_HUMAN Drebrin-like protein (SH3 domain-conta... 47 3e-05
sp|Q07266|DREB_RAT Drebrin (Developmentally regulated brain... 33 0.49
sp|Q16643|DREB_HUMAN Drebrin (Developmentally regulated bra... 33 0.49
sp|Q9QXS6|DREB_MOUSE Drebrin (Developmentally regulated bra... 33 0.49
>sp|Q14019|COTL1_HUMAN Coactosin-like protein
Length = 142
Score = 124 bits (312), Expect = 1e-28
Identities = 64/133 (48%), Positives = 85/133 (63%)
Frame = +3
Query: 3 IDKETISEAYEDVRNDATETTWALFGYDDKKIVVVKTGTLYESLLAEFNDDERHFAFVRM 182
IDKE AY VR+D + W F YD IV + G Y+ + + DD R FAFVR
Sbjct: 5 IDKEACRAAYNLVRDDGSAVIWVTFKYDGSTIVPGEQGAEYQHFIQQCTDDVRLFAFVRF 64
Query: 183 ITGDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEITESK 362
TGD MSKR+KFALIT+ G NVS +++A DK+LVKEVV ++A + SD+ E+ E
Sbjct: 65 TTGDAMSKRSKFALITWIGENVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKELEEDF 124
Query: 363 LRAALEKAGGANY 401
+++ L+KAGGANY
Sbjct: 125 IKSELKKAGGANY 137
>sp|Q9CQI6|COTL1_MOUSE Coactosin-like protein
Length = 142
Score = 122 bits (306), Expect = 5e-28
Identities = 64/133 (48%), Positives = 84/133 (63%)
Frame = +3
Query: 3 IDKETISEAYEDVRNDATETTWALFGYDDKKIVVVKTGTLYESLLAEFNDDERHFAFVRM 182
IDKE AY VR+D + W F YD IV G Y+ + + DD R FAFVR
Sbjct: 5 IDKEACRAAYNLVRDDGSAVIWVTFRYDGATIVPGDQGADYQHFIQQCTDDVRLFAFVRF 64
Query: 183 ITGDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEITESK 362
TGD MSKR+KFALIT+ G +VS +++A DK+LVKEVV ++A + SD+ E+ E
Sbjct: 65 TTGDAMSKRSKFALITWIGEDVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKELEEDF 124
Query: 363 LRAALEKAGGANY 401
+R+ L+KAGGANY
Sbjct: 125 IRSELKKAGGANY 137
>sp|P34121|COAC_DICDI Coactosin (Cytoskeletal p17 protein) (Cyclic AMP-regulated protein
p16)
Length = 146
Score = 92.8 bits (229), Expect = 4e-19
Identities = 47/142 (33%), Positives = 84/142 (59%), Gaps = 3/142 (2%)
Frame = +3
Query: 3 IDKETISEAYEDVRNDATETTWALFGYDDKKIVVV--KTGTLYESLLAEFND-DERHFAF 173
+ + AY++V D+ +T W LF Y+ K +V+ K + L E N ER +A+
Sbjct: 4 VSSTELKAAYDEVLADSNDTNWCLFKYEGKNKIVLSGKGSGGFAELAQEINQPSERLYAY 63
Query: 174 VRMITGDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEIT 353
+R+++GD+ SKR+KF I++CG V + KAN++V K+ VK+V+ + V++ + +++
Sbjct: 64 LRVVSGDDESKRSKFVFISWCGEEVGPLAKANVSVHKASVKQVIKNIGVEVHYTVADDLN 123
Query: 354 ESKLRAALEKAGGANYGSAK*T 419
E +L + K+ GA+Y K T
Sbjct: 124 EEELMTKVRKSSGADYSGNKST 145
>sp|Q9P7E8|APP1_SCHPO Protein app1
Length = 857
Score = 50.4 bits (119), Expect = 2e-06
Identities = 32/131 (24%), Positives = 64/131 (48%), Gaps = 3/131 (2%)
Frame = +3
Query: 18 ISEAYEDVRNDATETTWALFGYDDKK---IVVVKTGTLYESLLAEFNDDERHFAFVRMIT 188
I YE V + A + +WA+FGY+ + + VV +G + L EF+++ F F+R+
Sbjct: 14 IRNVYEKVLSGADDCSWAIFGYEKGQGNILKVVASGNDNDEFLDEFDENAVLFGFLRV-- 71
Query: 189 GDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEITESKLR 368
D + KF L+ +CG + +K ++ + V ++ Y V + + +++ +
Sbjct: 72 KDVNTGLNKFVLVCWCGE--AAARKGLFSIHMATVSNLLKGYHVQITGRESSDLNMDDII 129
Query: 369 AALEKAGGANY 401
+ A G+ Y
Sbjct: 130 RRVADASGSKY 140
>sp|Q62418|DBNL_MOUSE Drebrin-like protein (SH3 domain-containing protein 7)
(Actin-binding protein 1)
Length = 436
Score = 48.5 bits (114), Expect = 9e-06
Identities = 38/139 (27%), Positives = 61/139 (43%), Gaps = 3/139 (2%)
Frame = +3
Query: 18 ISEAYEDVRNDATETTWALFGYDDKKIVVVKTGT---LYESLLAEFNDDERHFAFVRMIT 188
+ EAY V + + T WALF Y+ + GT E L+ E N + +AF R+
Sbjct: 12 LQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEELVEELNSGKVMYAFCRV-- 69
Query: 189 GDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEITESKLR 368
D S KF LI + G V+ ++K S + + V + + ++ +
Sbjct: 70 KDPNSGLPKFVLINWTGEGVNDVRKGACANHVSTMANFLKGAHVTINARAEEDVEPECIM 129
Query: 369 AALEKAGGANYGSAK*TTN 425
+ KA GANY K +T+
Sbjct: 130 EKVAKASGANYSFHKESTS 148
>sp|Q9JHL4|DBNL_RAT Drebrin-like protein (SH3 domain-containing protein 7)
Length = 436
Score = 47.4 bits (111), Expect = 2e-05
Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 3/135 (2%)
Frame = +3
Query: 18 ISEAYEDVRNDATETTWALFGYDDKKIVVVKTGT---LYESLLAEFNDDERHFAFVRMIT 188
+ EAY V + + T WALF Y+ + GT E L+ E N + +AF R+
Sbjct: 12 LQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEELVEELNSGKVMYAFCRV-- 69
Query: 189 GDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEITESKLR 368
D S KF LI + G V+ ++K S + + V + + ++ +
Sbjct: 70 KDPNSGLPKFVLINWTGEGVNDVRKGACANHVSTMANFLKGAHVTINARAEEDVEPECIM 129
Query: 369 AALEKAGGANYGSAK 413
+ KA GANY K
Sbjct: 130 EKVAKASGANYSFHK 144
>sp|Q9UJU6|DBNL_HUMAN Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F)
(Cervical SH3P7) (HPK1-interacting protein of 55 kDa)
(HIP-55) (Cervical mucin-associated protein)
Length = 430
Score = 47.0 bits (110), Expect = 3e-05
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 3/135 (2%)
Frame = +3
Query: 18 ISEAYEDVRNDATETTWALFGYDDKKIVVVKTGT---LYESLLAEFNDDERHFAFVRMIT 188
+ EAY V + + T WALF Y+ + GT E ++ E N + +AF R+
Sbjct: 12 LQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEEMVEELNSGKVMYAFCRV-- 69
Query: 189 GDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDLFTSDKNEITESKLR 368
D S KF LI + G V+ ++K S + + V + + ++ +
Sbjct: 70 KDPNSGLPKFVLINWTGEGVNDVRKGACASHVSTMASFLKGAHVTINARAEEDVEPECIM 129
Query: 369 AALEKAGGANYGSAK 413
+ KA GANY K
Sbjct: 130 EKVAKASGANYSFHK 144
>sp|Q07266|DREB_RAT Drebrin (Developmentally regulated brain protein)
Length = 707
Score = 32.7 bits (73), Expect = 0.49
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +3
Query: 27 AYEDVRNDATETTWALFGY----DDKKIVVVKTGTLYESLLAEFNDDERHFAFVRMITGD 194
AYE+V + + WAL+ Y DD K+ G L E L F + + + F + D
Sbjct: 16 AYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQE-LSGHFENQKVMYGFCSV--KD 72
Query: 195 EMSKRAKFALITYCGANVSVMKK 263
+ K+ LI + G +V +K
Sbjct: 73 SQAALPKYVLINWVGEDVPDARK 95
>sp|Q16643|DREB_HUMAN Drebrin (Developmentally regulated brain protein)
Length = 649
Score = 32.7 bits (73), Expect = 0.49
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +3
Query: 27 AYEDVRNDATETTWALFGY----DDKKIVVVKTGTLYESLLAEFNDDERHFAFVRMITGD 194
AYE+V + + WAL+ Y DD K+ G L E L F + + + F + D
Sbjct: 16 AYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQE-LSGHFENQKVMYGFCSV--KD 72
Query: 195 EMSKRAKFALITYCGANVSVMKK 263
+ K+ LI + G +V +K
Sbjct: 73 SQAALPKYVLINWVGEDVPDARK 95
>sp|Q9QXS6|DREB_MOUSE Drebrin (Developmentally regulated brain protein)
Length = 706
Score = 32.7 bits (73), Expect = 0.49
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +3
Query: 27 AYEDVRNDATETTWALFGY----DDKKIVVVKTGTLYESLLAEFNDDERHFAFVRMITGD 194
AYE+V + + WAL+ Y DD K+ G L E L F + + + F + D
Sbjct: 16 AYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQE-LSGHFENQKVMYGFCSV--KD 72
Query: 195 EMSKRAKFALITYCGANVSVMKK 263
+ K+ LI + G +V +K
Sbjct: 73 SQAALPKYVLINWVGEDVPDARK 95
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,698,224
Number of Sequences: 369166
Number of extensions: 668432
Number of successful extensions: 2026
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2004
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2025
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3168768640
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)