Planaria EST Database

DrC_00120

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00120
         (458 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P15305|DYHC_ONCMY  Dynein heavy chain (DYHC)                    34   0.14 
sp|P31395|STMN1_CHICK  Stathmin                                    34   0.18 
sp|P16949|STMN1_HUMAN  Stathmin (Phosphoprotein p19) (pp19) ...    33   0.40 
sp|P13668|STMN1_RAT  Stathmin (Phosphoprotein p19) (pp19) (O...    33   0.40 
sp|Q8D2B6|Y438_WIGBR  Hypothetical UPF0350 protein WIGBR4380       33   0.40 
sp|Q89YY3|CLPB_BACTN  Chaperone clpB                               33   0.40 
sp|Q9DDU0|HXABA_BRARE  Homeobox protein Hox-A11a                   33   0.40 
sp|P54227|STMN1_MOUSE  Stathmin (Phosphoprotein p19) (pp19) ...    32   0.88 
sp|Q28298|RRBP1_CANFA  Ribosome-binding protein 1 (180 kDa r...    32   0.88 
sp|P11387|TOP1_HUMAN  DNA topoisomerase I                          31   1.2  

>sp|P15305|DYHC_ONCMY Dynein heavy chain (DYHC)
          Length = 515

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 29/154 (18%), Positives = 66/154 (42%), Gaps = 13/154 (8%)
 Frame = -1

Query: 455 HNPIFLVHYIMEDTIYQDLHIV*DKI----YPILHIFHHKFYRF-YHNHQKLFFPNFLQL 291
           ++ + ++ Y +   I   +H++   I    Y ILH+  +  +   Y  H   +  + +Q 
Sbjct: 85  YSTLHVIQYSILHVIQYSIHVIQYSIHVTQYSILHVIQYSIHVIQYSIHVIQYSTHVIQY 144

Query: 290 DDFFYFDCFHI---SLLHSQLILQNLHSLLHISVNILYLMLHILDHILCLMLHTDLH--- 129
                    H+   S+LH   ++Q    ++  S++++    H++ + + ++ ++ LH   
Sbjct: 145 SIHVIQYSIHVIQYSILH---VIQYSIHVIQYSIHVIQYSTHVIQYSIHVIQYSILHVIQ 201

Query: 128 --ILHQFYH*VLHIYHLPF*TNQICIRIAIYIEH 33
             ILH   + +LH+        Q  I +  Y  H
Sbjct: 202 YSILHVIQYSILHVIQYSIHVIQYSIHVIQYSIH 235


 Score = 33.5 bits (75), Expect = 0.23
 Identities = 21/122 (17%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
 Frame = -1

Query: 446 IFLVHYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRF-YHNHQKLFFPNFLQLDDFFYFD 270
           I ++ Y +    Y  LH++    Y ILH+  +  +   Y  H   +  + +Q      + 
Sbjct: 263 IHVIQYSIHVIQYSILHVI---QYSILHVIQYSIHVIQYSIHVIQYSIHVIQ------YS 313

Query: 269 CFHISLLHSQLILQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHILHQFYH*VLHIY 90
             H+      +I  ++H ++  S++++   +H++ + + ++ ++ LH++    H + +  
Sbjct: 314 ILHVIQYSIHVIQYSIH-VIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSI 372

Query: 89  HL 84
           H+
Sbjct: 373 HV 374


 Score = 32.7 bits (73), Expect = 0.40
 Identities = 24/141 (17%), Positives = 56/141 (39%), Gaps = 3/141 (2%)
 Frame = -1

Query: 446 IFLVHYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLQLDDFFYFDC 267
           I ++ Y +   I   +H++   I+ I +  H   Y   H  Q     + +Q         
Sbjct: 241 IHVIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSIL-HVIQYSIHVIQYS 299

Query: 266 FHISLLHSQLILQNLHSLLHISVNILYLMLHILD---HILCLMLHTDLHILHQFYH*VLH 96
            H+      +I  ++  ++  S++++   +H++    H++   +H   + +H   + +LH
Sbjct: 300 IHVIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIHVIQYSIHVIQYSILH 359

Query: 95  IYHLPF*TNQICIRIAIYIEH 33
           +        Q  I +  Y  H
Sbjct: 360 VIQYSIHVIQYSIHVIQYSIH 380


 Score = 32.0 bits (71), Expect = 0.68
 Identities = 29/151 (19%), Positives = 60/151 (39%), Gaps = 14/151 (9%)
 Frame = -1

Query: 443 FLVHYIMEDTI----YQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLQLDDFFY 276
           + +H I   T+    Y  LH++    Y  LH+  +        +  L    +  L    Y
Sbjct: 38  YSIHVIQYSTLHVIQYSTLHVI---QYSTLHVIQYSTLNVIQ-YSTLHVIQYSTLHVIQY 93

Query: 275 FDCFHISLLHSQLILQNLH----SLLHI---SVNILYLMLHILD---HILCLMLHTDLHI 126
               H+      +I  ++H    S+LH+   S++++   +H++    H++   +H   + 
Sbjct: 94  -SILHVIQYSIHVIQYSIHVTQYSILHVIQYSIHVIQYSIHVIQYSTHVIQYSIHVIQYS 152

Query: 125 LHQFYH*VLHIYHLPF*TNQICIRIAIYIEH 33
           +H   + +LH+        Q  I +  Y  H
Sbjct: 153 IHVIQYSILHVIQYSIHVIQYSIHVIQYSTH 183


 Score = 31.6 bits (70), Expect = 0.88
 Identities = 22/124 (17%), Positives = 60/124 (48%), Gaps = 6/124 (4%)
 Frame = -1

Query: 446 IFLVHYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRFYHN--HQKLFFPNFLQLDDFFYF 273
           I ++ Y +    Y  LH++    Y ILH+  +  +   ++  H   +  + +Q    +  
Sbjct: 379 IHVIQYSIHVIQYSILHVI---QYSILHVIQYSIHVIQYSILHVIQYSIHVIQ----YSI 431

Query: 272 DCFHISLLHSQLILQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHI----LHQFYH* 105
                S+LH  +I  ++H + +  ++++   +H++ + + ++ ++ LH+    +H   + 
Sbjct: 432 HVIQYSILH--VIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYS 489

Query: 104 VLHI 93
           +LH+
Sbjct: 490 ILHV 493


 Score = 31.2 bits (69), Expect = 1.2
 Identities = 22/126 (17%), Positives = 53/126 (42%), Gaps = 7/126 (5%)
 Frame = -1

Query: 440 LVHYIMEDTIYQDLHIV*DKI-----YPILHIFHHKFYRF-YHNHQKLFFPNFLQLD-DF 282
           ++ Y +    Y  LH++   I     Y ILH+  +  +   Y  H   +  + +Q     
Sbjct: 184 VIQYSIHVIQYSILHVIQYSILHVIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIHV 243

Query: 281 FYFDCFHISLLHSQLILQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHILHQFYH*V 102
             +   H+      +I  ++H + +    I Y +LH++ + +  ++   +H++    H +
Sbjct: 244 IQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSILHVIQYSIHVIQYSIHVI 303

Query: 101 LHIYHL 84
            +  H+
Sbjct: 304 QYSIHV 309


 Score = 30.4 bits (67), Expect = 2.0
 Identities = 25/139 (17%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
 Frame = -1

Query: 446 IFLVHYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLQLDDFFYFDC 267
           I ++ Y +    Y  LH++   I+ I +  H   Y  +     +    +  L    Y   
Sbjct: 343 IHVIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQY--- 399

Query: 266 FHISLLHSQLILQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHIL----HQFYH*VL 99
              S+LH  +I  ++H + +  ++++   +H++ + + ++ ++ LH++    H   + +L
Sbjct: 400 ---SILH--VIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSIL 454

Query: 98  HIYHLPF*TNQICIRIAIY 42
           H+        Q  I +  Y
Sbjct: 455 HVIQYSIHVIQYSIHVIQY 473


 Score = 30.0 bits (66), Expect = 2.6
 Identities = 21/122 (17%), Positives = 57/122 (46%), Gaps = 4/122 (3%)
 Frame = -1

Query: 446 IFLVHYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLQLDDFFYFDC 267
           + ++ Y +   I   +H++    Y ILH+  +  +   ++   + +     +   +    
Sbjct: 394 LHVIQYSILHVIQYSIHVI---QYSILHVIQYSIHVIQYSIHVIQYSILHVIQ--YSIHV 448

Query: 266 FHISLLHSQLILQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHI----LHQFYH*VL 99
              S+LH  +I  ++H + +    I Y +LH++ + + ++ ++ LH+    +H   + +L
Sbjct: 449 IQYSILH--VIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSILHVIQYSIHVIQYSIL 506

Query: 98  HI 93
           H+
Sbjct: 507 HV 508


 Score = 28.5 bits (62), Expect = 7.5
 Identities = 23/119 (19%), Positives = 56/119 (47%), Gaps = 1/119 (0%)
 Frame = -1

Query: 446 IFLVHYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRF-YHNHQKLFFPNFLQLDDFFYFD 270
           I ++ Y +   I   +H++    Y ILH+  +  +   Y  H   +  + +Q    +   
Sbjct: 336 IHVIQYSIH-VIQYSIHVI---QYSILHVIQYSIHVIQYSIHVIQYSIHVIQ----YSIH 387

Query: 269 CFHISLLHSQLILQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHILHQFYH*VLHI 93
               S+LH   ++Q  +S+LH+    ++++ + + H++   +H   + +H   + +LH+
Sbjct: 388 VIQYSILH---VIQ--YSILHVIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSILHV 441


 Score = 28.1 bits (61), Expect = 9.8
 Identities = 23/116 (19%), Positives = 56/116 (48%), Gaps = 8/116 (6%)
 Frame = -1

Query: 446 IFLVHYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLQLDDFFYFDC 267
           + ++ Y +    Y  LH++   I+ I +  H   Y   H  Q  +  + +Q      +  
Sbjct: 402 LHVIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSILHVIQ--YSIHVIQ------YSI 453

Query: 266 FHISLLHSQLILQNLH----SLLHI---SVNIL-YLMLHILDHILCLMLHTDLHIL 123
            H+      +I  ++H    S+LH+   S++++ Y +LH++ + + ++ ++ LH++
Sbjct: 454 LHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSILHVIQYSIHVIQYSILHVM 509

>sp|P31395|STMN1_CHICK Stathmin
          Length = 148

 Score = 33.9 bits (76), Expect = 0.18
 Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 6/108 (5%)
 Frame = +2

Query: 56  EYKFDLSRKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNAN 226
           E+     +K D   EE+  K++  EE    +EA + K+   K E  +KE L K +E N N
Sbjct: 34  EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNN 92

Query: 227 FAKSVVNAKV-KCENNQSKKSRQVVRNLEKIIFGD--YDKIDKTCDGK 361
           F+K        K E N+  +  Q+   LE++   D   +++ K  +GK
Sbjct: 93  FSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKEGK 140

>sp|P16949|STMN1_HUMAN Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18)
           (Leukemia-associated phosphoprotein p18) (pp17)
           (Prosolin) (Metablastin) (Pr22 protein)
          Length = 149

 Score = 32.7 bits (73), Expect = 0.40
 Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
 Frame = +2

Query: 56  EYKFDLSRKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNAN 226
           E+     +K D   EE+  K++  EE    +EA + K+   K E  +KE L K +E N N
Sbjct: 34  EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNN 92

Query: 227 FAKSVVNAKV-KCENNQSKKSRQVVRNLEKI 316
           F+K        K E N+  +  Q+   LE++
Sbjct: 93  FSKMAEEKLTHKMEANKENREAQMAAKLERL 123

>sp|P13668|STMN1_RAT Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18)
           (Leukemia-associated phosphoprotein p18) (pp17)
           (Prosolin) (Metablastin) (Pr22 protein)
          Length = 149

 Score = 32.7 bits (73), Expect = 0.40
 Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
 Frame = +2

Query: 56  EYKFDLSRKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNAN 226
           E+     +K D   EE+  K++  EE    +EA + K+   K E  +KE L K +E N N
Sbjct: 34  EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNN 92

Query: 227 FAKSVVNAKV-KCENNQSKKSRQVVRNLEKI 316
           F+K        K E N+  +  Q+   LE++
Sbjct: 93  FSKMAEEKLTHKMEANKENREAQMAAKLERL 123

>sp|Q8D2B6|Y438_WIGBR Hypothetical UPF0350 protein WIGBR4380
          Length = 84

 Score = 32.7 bits (73), Expect = 0.40
 Identities = 13/35 (37%), Positives = 20/35 (57%)
 Frame = -1

Query: 371 ILHIFHHKFYRFYHNHQKLFFPNFLQLDDFFYFDC 267
           I++ F  K + F  N +K+FF N L  DD + + C
Sbjct: 23  IINNFFKKEFDFLSNKEKIFFVNMLSYDDIYLYKC 57

>sp|Q89YY3|CLPB_BACTN Chaperone clpB
          Length = 862

 Score = 32.7 bits (73), Expect = 0.40
 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 9/115 (7%)
 Frame = +2

Query: 89  DKCEELNGKIDEECEDPYEALDKECD-PKYEALDKECLPKYVEVNANFAKSVVNAKVKCE 265
           ++ +E++ KI ++ E   EA+ +E D PK E + KE L +  EV  +F      AK + E
Sbjct: 408 EELDEISRKI-KQLEIEREAIKRENDKPKLEIIGKE-LAELKEVEKSF-----KAKWQSE 460

Query: 266 NNQSKKSRQVVRNLEKIIF--------GDYDKIDKTCDGKYAELDKSCLKRYEDL 406
                K +Q    +E + F        GDY K+ +   GK   LDK      E L
Sbjct: 461 KTLMDKIQQNKVEIENLKFEAEKAEREGDYGKVAEIRYGKLQALDKEIEDTQEKL 515

>sp|Q9DDU0|HXABA_BRARE Homeobox protein Hox-A11a
          Length = 284

 Score = 32.7 bits (73), Expect = 0.40
 Identities = 26/97 (26%), Positives = 37/97 (38%), Gaps = 9/97 (9%)
 Frame = +2

Query: 116 IDEECEDPYEALDKECDPKYEALDKECLPKYVEVNANFAKSVVNAKVKCENNQSKKSR-- 289
           ID   + P+      C P  +++ KECLP    V   F K+  +A     +N +  S   
Sbjct: 68  IDPSTKWPHRGPLAHCYPSEDSVHKECLPAVTTVGEMFPKNNASAYYHSTSNTTSASNFY 127

Query: 290 -QVVRN------LEKIIFGDYDKIDKTCDGKYAELDK 379
             V RN       ++     Y   D   D  YA  DK
Sbjct: 128 GNVGRNGVLPQAFDQFFDTAYGGSDSVVDNDYAARDK 164

>sp|P54227|STMN1_MOUSE Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18)
           (Leukemia-associated phosphoprotein p18) (pp17)
           (Prosolin) (Metablastin) (Pr22 protein)
           (Leukemia-associated gene protein)
          Length = 149

 Score = 31.6 bits (70), Expect = 0.88
 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
 Frame = +2

Query: 77  RKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNANFAKSVVN 247
           +K D   EE+  K++  EE    +EA + K+   K E  +KE L K +E N NF+K    
Sbjct: 41  KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNNFSKMAEE 99

Query: 248 AKV-KCENNQSKKSRQVVRNLEKI 316
               K E N+  +  Q+   LE++
Sbjct: 100 KLTHKMEANKENREAQMAAKLERL 123

>sp|Q28298|RRBP1_CANFA Ribosome-binding protein 1 (180 kDa ribosome receptor) (RRp)
          Length = 1534

 Score = 31.6 bits (70), Expect = 0.88
 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
 Frame = +2

Query: 89   DKCEELNGKIDEECEDPYEALDKECDPKYEAL-DKECLPKYVEVNANFAKSVVNAKVKCE 265
            D   +L  K+  E E+    L  ECD     L + E + K ++ +    + V  AKV   
Sbjct: 1234 DPSSDLASKL-REAEETQNNLQAECDQYRTILAETEGMLKDLQKSVEEEEQVWKAKVSAT 1292

Query: 266  NNQSKKSRQVVRNLEKII 319
              + +KSR  V++LE I+
Sbjct: 1293 EEELQKSRVTVKHLEDIV 1310

>sp|P11387|TOP1_HUMAN DNA topoisomerase I
          Length = 765

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 3/104 (2%)
 Frame = +2

Query: 137 PYEALDKECDPKYEALDKECLPKYVEVNANFAKSV---VNAKVKCENNQSKKSRQVVRNL 307
           PYE L +     Y+    +  PK  EV   FAK +      K     N  K  R+ + N 
Sbjct: 230 PYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNE 289

Query: 308 EKIIFGDYDKIDKTCDGKYAELDKSCLKRYEDLDKLCLPLYNEQ 439
           EK I  +  K D T   +Y +      K+    +KL +   NE+
Sbjct: 290 EKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEK 333

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,107,033
Number of Sequences: 369166
Number of extensions: 816628
Number of successful extensions: 3424
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3223
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3382
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2534533995
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00120

  1. Dr_sW_003_P24
  2. Dr_sW_010_D03
  3. Dr_sW_008_L15
  4. Dr_sW_010_C04
  5. Dr_sW_009_M07
  6. Dr_sW_025_M04
  7. Dr_sW_013_M19