Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_C04
(414 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P31395|STMN1_CHICK Stathmin 34 0.13
sp|P16949|STMN1_HUMAN Stathmin (Phosphoprotein p19) (pp19) ... 33 0.30
sp|P13668|STMN1_RAT Stathmin (Phosphoprotein p19) (pp19) (O... 33 0.30
sp|Q8D2B6|Y438_WIGBR Hypothetical UPF0350 protein WIGBR4380 33 0.30
sp|Q89YY3|CLPB_BACTN Chaperone clpB 33 0.30
sp|Q9DDU0|HXABA_BRARE Homeobox protein Hox-A11a 33 0.30
sp|P15305|DYHC_ONCMY Dynein heavy chain (DYHC) 33 0.30
sp|P54227|STMN1_MOUSE Stathmin (Phosphoprotein p19) (pp19) ... 32 0.66
sp|Q28298|RRBP1_CANFA Ribosome-binding protein 1 (180 kDa r... 32 0.66
sp|Q15431|SYCP1_HUMAN Synaptonemal complex protein 1 (SCP-1... 31 0.86
>sp|P31395|STMN1_CHICK Stathmin
Length = 148
Score = 33.9 bits (76), Expect = 0.13
Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 6/108 (5%)
Frame = +3
Query: 12 EYKFDLSRKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNAN 182
E+ +K D EE+ K++ EE +EA + K+ K E +KE L K +E N N
Sbjct: 34 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNN 92
Query: 183 FAKSVVNAKV-KCENNQSKKSRQVVRNLEKIIFGD--YDKIDKTCDGK 317
F+K K E N+ + Q+ LE++ D +++ K +GK
Sbjct: 93 FSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKEGK 140
>sp|P16949|STMN1_HUMAN Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18)
(Leukemia-associated phosphoprotein p18) (pp17)
(Prosolin) (Metablastin) (Pr22 protein)
Length = 149
Score = 32.7 bits (73), Expect = 0.30
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Frame = +3
Query: 12 EYKFDLSRKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNAN 182
E+ +K D EE+ K++ EE +EA + K+ K E +KE L K +E N N
Sbjct: 34 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNN 92
Query: 183 FAKSVVNAKV-KCENNQSKKSRQVVRNLEKI 272
F+K K E N+ + Q+ LE++
Sbjct: 93 FSKMAEEKLTHKMEANKENREAQMAAKLERL 123
>sp|P13668|STMN1_RAT Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18)
(Leukemia-associated phosphoprotein p18) (pp17)
(Prosolin) (Metablastin) (Pr22 protein)
Length = 149
Score = 32.7 bits (73), Expect = 0.30
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Frame = +3
Query: 12 EYKFDLSRKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNAN 182
E+ +K D EE+ K++ EE +EA + K+ K E +KE L K +E N N
Sbjct: 34 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNN 92
Query: 183 FAKSVVNAKV-KCENNQSKKSRQVVRNLEKI 272
F+K K E N+ + Q+ LE++
Sbjct: 93 FSKMAEEKLTHKMEANKENREAQMAAKLERL 123
>sp|Q8D2B6|Y438_WIGBR Hypothetical UPF0350 protein WIGBR4380
Length = 84
Score = 32.7 bits (73), Expect = 0.30
Identities = 13/35 (37%), Positives = 20/35 (57%)
Frame = -1
Query: 327 ILHIFHHKFYRFYHNHQKLFFPNFLQLDDFFYFDC 223
I++ F K + F N +K+FF N L DD + + C
Sbjct: 23 IINNFFKKEFDFLSNKEKIFFVNMLSYDDIYLYKC 57
>sp|Q89YY3|CLPB_BACTN Chaperone clpB
Length = 862
Score = 32.7 bits (73), Expect = 0.30
Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 9/115 (7%)
Frame = +3
Query: 45 DKCEELNGKIDEECEDPYEALDKECD-PKYEALDKECLPKYVEVNANFAKSVVNAKVKCE 221
++ +E++ KI ++ E EA+ +E D PK E + KE L + EV +F AK + E
Sbjct: 408 EELDEISRKI-KQLEIEREAIKRENDKPKLEIIGKE-LAELKEVEKSF-----KAKWQSE 460
Query: 222 NNQSKKSRQVVRNLEKIIF--------GDYDKIDKTCDGKYAELDKSCLKRYEDL 362
K +Q +E + F GDY K+ + GK LDK E L
Sbjct: 461 KTLMDKIQQNKVEIENLKFEAEKAEREGDYGKVAEIRYGKLQALDKEIEDTQEKL 515
>sp|Q9DDU0|HXABA_BRARE Homeobox protein Hox-A11a
Length = 284
Score = 32.7 bits (73), Expect = 0.30
Identities = 26/97 (26%), Positives = 37/97 (38%), Gaps = 9/97 (9%)
Frame = +3
Query: 72 IDEECEDPYEALDKECDPKYEALDKECLPKYVEVNANFAKSVVNAKVKCENNQSKKSR-- 245
ID + P+ C P +++ KECLP V F K+ +A +N + S
Sbjct: 68 IDPSTKWPHRGPLAHCYPSEDSVHKECLPAVTTVGEMFPKNNASAYYHSTSNTTSASNFY 127
Query: 246 -QVVRN------LEKIIFGDYDKIDKTCDGKYAELDK 335
V RN ++ Y D D YA DK
Sbjct: 128 GNVGRNGVLPQAFDQFFDTAYGGSDSVVDNDYAARDK 164
>sp|P15305|DYHC_ONCMY Dynein heavy chain (DYHC)
Length = 515
Score = 32.7 bits (73), Expect = 0.30
Identities = 21/122 (17%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = -1
Query: 402 IFLVLYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRF-YHNHQKLFFPNFLQLDDFFYFD 226
I ++ Y + Y LH++ Y ILH+ + + Y H + + +Q +
Sbjct: 263 IHVIQYSIHVIQYSILHVI---QYSILHVIQYSIHVIQYSIHVIQYSIHVIQ------YS 313
Query: 225 CFHISLLHSQLIWQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHILHQFYH*VLHIY 46
H+ +I ++H ++ S++++ +H++ + + ++ ++ LH++ H + +
Sbjct: 314 ILHVIQYSIHVIQYSIH-VIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSI 372
Query: 45 HL 40
H+
Sbjct: 373 HV 374
Score = 32.0 bits (71), Expect = 0.51
Identities = 22/127 (17%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Frame = -1
Query: 414 LHNPIFLVLYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRF-YHNHQKLFFPNFLQLD-D 241
+H + +L++++ Y LH++ Y ILH+ + + Y H + + +Q
Sbjct: 189 IHVIQYSILHVIQ---YSILHVI---QYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIH 242
Query: 240 FFYFDCFHISLLHSQLIWQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHILHQFYH* 61
+ H+ +I ++H + + I Y +LH++ + + ++ +H++ H
Sbjct: 243 VIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSILHVIQYSIHVIQYSIHV 302
Query: 60 VLHIYHL 40
+ + H+
Sbjct: 303 IQYSIHV 309
Score = 30.8 bits (68), Expect = 1.1
Identities = 22/124 (17%), Positives = 60/124 (48%), Gaps = 6/124 (4%)
Frame = -1
Query: 402 IFLVLYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRFYHN--HQKLFFPNFLQLDDFFYF 229
I ++ Y + Y LH++ Y ILH+ + + ++ H + + +Q +
Sbjct: 379 IHVIQYSIHVIQYSILHVI---QYSILHVIQYSIHVIQYSILHVIQYSIHVIQ----YSI 431
Query: 228 DCFHISLLHSQLIWQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHI----LHQFYH* 61
S+LH +I ++H + + ++++ +H++ + + ++ ++ LH+ +H +
Sbjct: 432 HVIQYSILH--VIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYS 489
Query: 60 VLHI 49
+LH+
Sbjct: 490 ILHV 493
Score = 30.4 bits (67), Expect = 1.5
Identities = 23/131 (17%), Positives = 64/131 (48%), Gaps = 6/131 (4%)
Frame = -1
Query: 414 LHNPIFLVLYIMEDTIY---QDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLQLD 244
LH + +L++++ +I+ +H++ I+ I + H Y H Q + + +Q
Sbjct: 205 LHVIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQ--YSIHVIQYS 262
Query: 243 DFFYFDCFHI---SLLHSQLIWQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHILHQ 73
H+ S+LH +I ++ ++ S++++ +H++ + + ++ ++ LH++
Sbjct: 263 IHVIQYSIHVIQYSILH--VIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQY 320
Query: 72 FYH*VLHIYHL 40
H + + H+
Sbjct: 321 SIHVIQYSIHV 331
Score = 30.4 bits (67), Expect = 1.5
Identities = 27/130 (20%), Positives = 59/130 (45%), Gaps = 8/130 (6%)
Frame = -1
Query: 414 LHNPIFLVLYIMEDTI----YQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLQL 247
LH + +L++++ +I Y LH++ I+ I + H Y H Q
Sbjct: 394 LHVIQYSILHVIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSILHVIQ---------- 443
Query: 246 DDFFYFDCFHISLLHSQLIWQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHI----L 79
+ S+LH +I ++H + + I Y +LH++ + + ++ ++ LH+ +
Sbjct: 444 ---YSIHVIQYSILH--VIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSILHVIQYSI 498
Query: 78 HQFYH*VLHI 49
H + +LH+
Sbjct: 499 HVIQYSILHV 508
Score = 30.0 bits (66), Expect = 1.9
Identities = 19/129 (14%), Positives = 55/129 (42%), Gaps = 7/129 (5%)
Frame = -1
Query: 414 LHNPIFLVLYIMEDTIY---QDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLQLD 244
+H + +L++++ +I+ +H++ I+ I + H Y H Q
Sbjct: 350 IHVIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSILHVIQYSI 409
Query: 243 DFFYFDCFHISLLHSQLIWQNLHSLLHISVNILYLMLHILD----HILCLMLHTDLHILH 76
+ H+ +I ++H + + ++++ +H++ H++ +H + +H
Sbjct: 410 HVIQYSILHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSILHVIQYSIHVIQYSIH 469
Query: 75 QFYH*VLHI 49
+ +LH+
Sbjct: 470 VIQYSILHV 478
Score = 29.3 bits (64), Expect = 3.3
Identities = 21/124 (16%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = -1
Query: 402 IFLVLYIMEDTIYQDLHIV*DKIYPI---LHIFHHKFYRFYHNHQKLFFPNFLQLDDFFY 232
I ++ Y + I +H++ I+ I +H+ + + ++ + + L + +
Sbjct: 350 IHVIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSILHVIQYS- 408
Query: 231 FDCFHISLLHSQLIWQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHILHQFYH*VLH 52
S+LH +I ++H + + I Y +LH++ + + ++ ++ LH++ H + +
Sbjct: 409 IHVIQYSILH--VIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSILHVIQYSIHVIQY 466
Query: 51 IYHL 40
H+
Sbjct: 467 SIHV 470
Score = 27.7 bits (60), Expect = 9.6
Identities = 16/109 (14%), Positives = 47/109 (43%)
Frame = -1
Query: 366 YQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLQLDDFFYFDCFHISLLHSQLIW 187
Y LH++ Y ILH+ + + ++ + H+ +I
Sbjct: 85 YSTLHVI---QYSILHVIQYSIHVIQYSIHVT------------QYSILHVIQYSIHVIQ 129
Query: 186 QNLHSLLHISVNILYLMLHILDHILCLMLHTDLHILHQFYH*VLHIYHL 40
++H ++ S +++ +H++ + + ++ ++ LH++ H + + H+
Sbjct: 130 YSIH-VIQYSTHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSIHV 177
>sp|P54227|STMN1_MOUSE Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18)
(Leukemia-associated phosphoprotein p18) (pp17)
(Prosolin) (Metablastin) (Pr22 protein)
(Leukemia-associated gene protein)
Length = 149
Score = 31.6 bits (70), Expect = 0.66
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Frame = +3
Query: 33 RKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNANFAKSVVN 203
+K D EE+ K++ EE +EA + K+ K E +KE L K +E N NF+K
Sbjct: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNNFSKMAEE 99
Query: 204 AKV-KCENNQSKKSRQVVRNLEKI 272
K E N+ + Q+ LE++
Sbjct: 100 KLTHKMEANKENREAQMAAKLERL 123
>sp|Q28298|RRBP1_CANFA Ribosome-binding protein 1 (180 kDa ribosome receptor) (RRp)
Length = 1534
Score = 31.6 bits (70), Expect = 0.66
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Frame = +3
Query: 45 DKCEELNGKIDEECEDPYEALDKECDPKYEAL-DKECLPKYVEVNANFAKSVVNAKVKCE 221
D +L K+ E E+ L ECD L + E + K ++ + + V AKV
Sbjct: 1234 DPSSDLASKL-REAEETQNNLQAECDQYRTILAETEGMLKDLQKSVEEEEQVWKAKVSAT 1292
Query: 222 NNQSKKSRQVVRNLEKII 275
+ +KSR V++LE I+
Sbjct: 1293 EEELQKSRVTVKHLEDIV 1310
>sp|Q15431|SYCP1_HUMAN Synaptonemal complex protein 1 (SCP-1 protein)
Length = 976
Score = 31.2 bits (69), Expect = 0.86
Identities = 32/149 (21%), Positives = 61/149 (40%), Gaps = 27/149 (18%)
Frame = +3
Query: 36 KGDDKCEELNGKID------EECEDPYEALDKECDPKYEALD-------------KECLP 158
K ++ C L +++ EE + +AL K+ + + L+ +
Sbjct: 596 KSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQ 655
Query: 159 KYVEVNANFAKSVVNAKVKCEN--NQSKKSRQVVRNLEKIIFGDYDKIDKTCDGKYAELD 332
K+ E+ + K + + K+ EN + +K++ + K+ +IDK C K AE+
Sbjct: 656 KFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVKL----QKEIDKRCQHKIAEMV 711
Query: 333 KSCLKRYEDLDKLC------LPLYKEQEK 401
K DK+ L LYK +E+
Sbjct: 712 ALMEKHKHQYDKIIEERDSELGLYKSKEQ 740
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,919,583
Number of Sequences: 369166
Number of extensions: 764791
Number of successful extensions: 3264
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3081
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3226
length of database: 68,354,980
effective HSP length: 99
effective length of database: 50,066,215
effective search space used: 1902516170
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)