Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_M19
(458 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P31395|STMN1_CHICK Stathmin 34 0.18
sp|P16949|STMN1_HUMAN Stathmin (Phosphoprotein p19) (pp19) ... 33 0.40
sp|P13668|STMN1_RAT Stathmin (Phosphoprotein p19) (pp19) (O... 33 0.40
sp|Q8D2B6|Y438_WIGBR Hypothetical UPF0350 protein WIGBR4380 33 0.40
sp|Q89YY3|CLPB_BACTN Chaperone clpB 33 0.40
sp|Q9DDU0|HXABA_BRARE Homeobox protein Hox-A11a 33 0.40
sp|P15305|DYHC_ONCMY Dynein heavy chain (DYHC) 33 0.40
sp|P54227|STMN1_MOUSE Stathmin (Phosphoprotein p19) (pp19) ... 32 0.88
sp|Q28298|RRBP1_CANFA Ribosome-binding protein 1 (180 kDa r... 32 0.88
sp|Q15431|SYCP1_HUMAN Synaptonemal complex protein 1 (SCP-1... 31 1.2
>sp|P31395|STMN1_CHICK Stathmin
Length = 148
Score = 33.9 bits (76), Expect = 0.18
Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 6/108 (5%)
Frame = +2
Query: 56 EYKFDLSRKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNAN 226
E+ +K D EE+ K++ EE +EA + K+ K E +KE L K +E N N
Sbjct: 34 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNN 92
Query: 227 FAKSVVNAKV-KCENNQSKKSRQVVRNLEKIIFGD--YDKIDKTCDGK 361
F+K K E N+ + Q+ LE++ D +++ K +GK
Sbjct: 93 FSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKEGK 140
>sp|P16949|STMN1_HUMAN Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18)
(Leukemia-associated phosphoprotein p18) (pp17)
(Prosolin) (Metablastin) (Pr22 protein)
Length = 149
Score = 32.7 bits (73), Expect = 0.40
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Frame = +2
Query: 56 EYKFDLSRKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNAN 226
E+ +K D EE+ K++ EE +EA + K+ K E +KE L K +E N N
Sbjct: 34 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNN 92
Query: 227 FAKSVVNAKV-KCENNQSKKSRQVVRNLEKI 316
F+K K E N+ + Q+ LE++
Sbjct: 93 FSKMAEEKLTHKMEANKENREAQMAAKLERL 123
>sp|P13668|STMN1_RAT Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18)
(Leukemia-associated phosphoprotein p18) (pp17)
(Prosolin) (Metablastin) (Pr22 protein)
Length = 149
Score = 32.7 bits (73), Expect = 0.40
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Frame = +2
Query: 56 EYKFDLSRKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNAN 226
E+ +K D EE+ K++ EE +EA + K+ K E +KE L K +E N N
Sbjct: 34 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNN 92
Query: 227 FAKSVVNAKV-KCENNQSKKSRQVVRNLEKI 316
F+K K E N+ + Q+ LE++
Sbjct: 93 FSKMAEEKLTHKMEANKENREAQMAAKLERL 123
>sp|Q8D2B6|Y438_WIGBR Hypothetical UPF0350 protein WIGBR4380
Length = 84
Score = 32.7 bits (73), Expect = 0.40
Identities = 13/35 (37%), Positives = 20/35 (57%)
Frame = -1
Query: 371 ILHIFHHKFYRFYHNHQKLFFPNFLQLDDFFYFDC 267
I++ F K + F N +K+FF N L DD + + C
Sbjct: 23 IINNFFKKEFDFLSNKEKIFFVNMLSYDDIYLYKC 57
>sp|Q89YY3|CLPB_BACTN Chaperone clpB
Length = 862
Score = 32.7 bits (73), Expect = 0.40
Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 9/115 (7%)
Frame = +2
Query: 89 DKCEELNGKIDEECEDPYEALDKECD-PKYEALDKECLPKYVEVNANFAKSVVNAKVKCE 265
++ +E++ KI ++ E EA+ +E D PK E + KE L + EV +F AK + E
Sbjct: 408 EELDEISRKI-KQLEIEREAIKRENDKPKLEIIGKE-LAELKEVEKSF-----KAKWQSE 460
Query: 266 NNQSKKSRQVVRNLEKIIF--------GDYDKIDKTCDGKYAELDKSCLKRYEDL 406
K +Q +E + F GDY K+ + GK LDK E L
Sbjct: 461 KTLMDKIQQNKVEIENLKFEAEKAEREGDYGKVAEIRYGKLQALDKEIEDTQEKL 515
>sp|Q9DDU0|HXABA_BRARE Homeobox protein Hox-A11a
Length = 284
Score = 32.7 bits (73), Expect = 0.40
Identities = 26/97 (26%), Positives = 37/97 (38%), Gaps = 9/97 (9%)
Frame = +2
Query: 116 IDEECEDPYEALDKECDPKYEALDKECLPKYVEVNANFAKSVVNAKVKCENNQSKKSR-- 289
ID + P+ C P +++ KECLP V F K+ +A +N + S
Sbjct: 68 IDPSTKWPHRGPLAHCYPSEDSVHKECLPAVTTVGEMFPKNNASAYYHSTSNTTSASNFY 127
Query: 290 -QVVRN------LEKIIFGDYDKIDKTCDGKYAELDK 379
V RN ++ Y D D YA DK
Sbjct: 128 GNVGRNGVLPQAFDQFFDTAYGGSDSVVDNDYAARDK 164
>sp|P15305|DYHC_ONCMY Dynein heavy chain (DYHC)
Length = 515
Score = 32.7 bits (73), Expect = 0.40
Identities = 21/122 (17%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = -1
Query: 446 IFLVLYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRF-YHNHQKLFFPNFLQLDDFFYFD 270
I ++ Y + Y LH++ Y ILH+ + + Y H + + +Q +
Sbjct: 263 IHVIQYSIHVIQYSILHVI---QYSILHVIQYSIHVIQYSIHVIQYSIHVIQ------YS 313
Query: 269 CFHISLLHSQLIWQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHILHQFYH*VLHIY 90
H+ +I ++H ++ S++++ +H++ + + ++ ++ LH++ H + +
Sbjct: 314 ILHVIQYSIHVIQYSIH-VIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSI 372
Query: 89 HL 84
H+
Sbjct: 373 HV 374
Score = 32.3 bits (72), Expect = 0.52
Identities = 31/149 (20%), Positives = 62/149 (41%), Gaps = 7/149 (4%)
Frame = -1
Query: 458 LHNPIFLVLYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLQLDDFF 279
LH + +L++++ Y LH++ I+ I + H Y + + + L
Sbjct: 197 LHVIQYSILHVIQ---YSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQ 253
Query: 278 YFDCFHISLLHSQLIWQNLH----SLLHISVNILYLMLHILD---HILCLMLHTDLHILH 120
Y H+ +I ++H S+LH+ I Y +LH++ H++ +H + +H
Sbjct: 254 Y--SIHVIQYSIHVIQYSIHVIQYSILHV---IQYSILHVIQYSIHVIQYSIHVIQYSIH 308
Query: 119 QFYH*VLHIYHLPF*TNQICIRIAIYIEH 33
+ +LH+ Q I + Y H
Sbjct: 309 VIQYSILHVIQYSIHVIQYSIHVIQYSIH 337
Score = 32.0 bits (71), Expect = 0.68
Identities = 22/127 (17%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Frame = -1
Query: 458 LHNPIFLVLYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRF-YHNHQKLFFPNFLQLD-D 285
+H + +L++++ Y LH++ Y ILH+ + + Y H + + +Q
Sbjct: 189 IHVIQYSILHVIQ---YSILHVI---QYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIH 242
Query: 284 FFYFDCFHISLLHSQLIWQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHILHQFYH* 105
+ H+ +I ++H + + I Y +LH++ + + ++ +H++ H
Sbjct: 243 VIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSILHVIQYSIHVIQYSIHV 302
Query: 104 VLHIYHL 84
+ + H+
Sbjct: 303 IQYSIHV 309
Score = 32.0 bits (71), Expect = 0.68
Identities = 24/141 (17%), Positives = 56/141 (39%), Gaps = 3/141 (2%)
Frame = -1
Query: 446 IFLVLYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLQLDDFFYFDC 267
I ++ Y + I +H++ I+ I + H Y H Q + +Q
Sbjct: 241 IHVIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSIL-HVIQYSIHVIQYS 299
Query: 266 FHISLLHSQLIWQNLHSLLHISVNILYLMLHILD---HILCLMLHTDLHILHQFYH*VLH 96
H+ +I ++ ++ S++++ +H++ H++ +H + +H + +LH
Sbjct: 300 IHVIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIHVIQYSIHVIQYSILH 359
Query: 95 IYHLPF*TNQICIRIAIYIEH 33
+ Q I + Y H
Sbjct: 360 VIQYSIHVIQYSIHVIQYSIH 380
Score = 30.8 bits (68), Expect = 1.5
Identities = 22/124 (17%), Positives = 60/124 (48%), Gaps = 6/124 (4%)
Frame = -1
Query: 446 IFLVLYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRFYHN--HQKLFFPNFLQLDDFFYF 273
I ++ Y + Y LH++ Y ILH+ + + ++ H + + +Q +
Sbjct: 379 IHVIQYSIHVIQYSILHVI---QYSILHVIQYSIHVIQYSILHVIQYSIHVIQ----YSI 431
Query: 272 DCFHISLLHSQLIWQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHI----LHQFYH* 105
S+LH +I ++H + + ++++ +H++ + + ++ ++ LH+ +H +
Sbjct: 432 HVIQYSILH--VIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYS 489
Query: 104 VLHI 93
+LH+
Sbjct: 490 ILHV 493
Score = 30.4 bits (67), Expect = 2.0
Identities = 27/152 (17%), Positives = 63/152 (41%), Gaps = 16/152 (10%)
Frame = -1
Query: 440 LVLYIMEDTIYQDLHIV*DKIYPILHIFHHK-FYRFYHNHQKLFFPNFLQLDDFFYFDCF 264
++ Y + Y LH++ Y LH+ + + ++ + + L + +
Sbjct: 35 VIQYSIHVIQYSTLHVI---QYSTLHVIQYSTLHVIQYSTLNVIQYSTLHVIQYSTLHVI 91
Query: 263 HISLLHS-----QLIWQNLH----SLLHI---SVNILYLMLHILD---HILCLMLHTDLH 129
S+LH +I ++H S+LH+ S++++ +H++ H++ +H +
Sbjct: 92 QYSILHVIQYSIHVIQYSIHVTQYSILHVIQYSIHVIQYSIHVIQYSTHVIQYSIHVIQY 151
Query: 128 ILHQFYH*VLHIYHLPF*TNQICIRIAIYIEH 33
+H + +LH+ Q I + Y H
Sbjct: 152 SIHVIQYSILHVIQYSIHVIQYSIHVIQYSTH 183
Score = 30.4 bits (67), Expect = 2.0
Identities = 27/130 (20%), Positives = 59/130 (45%), Gaps = 8/130 (6%)
Frame = -1
Query: 458 LHNPIFLVLYIMEDTI----YQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLQL 291
LH + +L++++ +I Y LH++ I+ I + H Y H Q
Sbjct: 394 LHVIQYSILHVIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSILHVIQ---------- 443
Query: 290 DDFFYFDCFHISLLHSQLIWQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHI----L 123
+ S+LH +I ++H + + I Y +LH++ + + ++ ++ LH+ +
Sbjct: 444 ---YSIHVIQYSILH--VIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSILHVIQYSI 498
Query: 122 HQFYH*VLHI 93
H + +LH+
Sbjct: 499 HVIQYSILHV 508
Score = 30.0 bits (66), Expect = 2.6
Identities = 19/129 (14%), Positives = 55/129 (42%), Gaps = 7/129 (5%)
Frame = -1
Query: 458 LHNPIFLVLYIMEDTIY---QDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLQLD 288
+H + +L++++ +I+ +H++ I+ I + H Y H Q
Sbjct: 350 IHVIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSILHVIQYSI 409
Query: 287 DFFYFDCFHISLLHSQLIWQNLHSLLHISVNILYLMLHILD----HILCLMLHTDLHILH 120
+ H+ +I ++H + + ++++ +H++ H++ +H + +H
Sbjct: 410 HVIQYSILHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSILHVIQYSIHVIQYSIH 469
Query: 119 QFYH*VLHI 93
+ +LH+
Sbjct: 470 VIQYSILHV 478
Score = 29.6 bits (65), Expect = 3.4
Identities = 24/133 (18%), Positives = 60/133 (45%), Gaps = 9/133 (6%)
Frame = -1
Query: 413 IYQDLHIV*DKIYPILHIFHHKFYRF-YHNHQKLFFPNFLQLD-DFFYFDCFHI---SLL 249
I +H++ Y ILH+ + + Y H + + +Q + H+ S+L
Sbjct: 346 IQYSIHVI---QYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSIL 402
Query: 248 HSQLIWQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHIL----HQFYH*VLHIYHLP 81
H +I ++H + + ++++ +H++ + + ++ ++ LH++ H + +LH+
Sbjct: 403 H--VIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSILHVIQYS 460
Query: 80 F*TNQICIRIAIY 42
Q I + Y
Sbjct: 461 IHVIQYSIHVIQY 473
Score = 29.3 bits (64), Expect = 4.4
Identities = 21/124 (16%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = -1
Query: 446 IFLVLYIMEDTIYQDLHIV*DKIYPI---LHIFHHKFYRFYHNHQKLFFPNFLQLDDFFY 276
I ++ Y + I +H++ I+ I +H+ + + ++ + + L + +
Sbjct: 350 IHVIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSILHVIQYS- 408
Query: 275 FDCFHISLLHSQLIWQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHILHQFYH*VLH 96
S+LH +I ++H + + I Y +LH++ + + ++ ++ LH++ H + +
Sbjct: 409 IHVIQYSILH--VIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSILHVIQYSIHVIQY 466
Query: 95 IYHL 84
H+
Sbjct: 467 SIHV 470
>sp|P54227|STMN1_MOUSE Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18)
(Leukemia-associated phosphoprotein p18) (pp17)
(Prosolin) (Metablastin) (Pr22 protein)
(Leukemia-associated gene protein)
Length = 149
Score = 31.6 bits (70), Expect = 0.88
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Frame = +2
Query: 77 RKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNANFAKSVVN 247
+K D EE+ K++ EE +EA + K+ K E +KE L K +E N NF+K
Sbjct: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNNFSKMAEE 99
Query: 248 AKV-KCENNQSKKSRQVVRNLEKI 316
K E N+ + Q+ LE++
Sbjct: 100 KLTHKMEANKENREAQMAAKLERL 123
>sp|Q28298|RRBP1_CANFA Ribosome-binding protein 1 (180 kDa ribosome receptor) (RRp)
Length = 1534
Score = 31.6 bits (70), Expect = 0.88
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Frame = +2
Query: 89 DKCEELNGKIDEECEDPYEALDKECDPKYEAL-DKECLPKYVEVNANFAKSVVNAKVKCE 265
D +L K+ E E+ L ECD L + E + K ++ + + V AKV
Sbjct: 1234 DPSSDLASKL-REAEETQNNLQAECDQYRTILAETEGMLKDLQKSVEEEEQVWKAKVSAT 1292
Query: 266 NNQSKKSRQVVRNLEKII 319
+ +KSR V++LE I+
Sbjct: 1293 EEELQKSRVTVKHLEDIV 1310
>sp|Q15431|SYCP1_HUMAN Synaptonemal complex protein 1 (SCP-1 protein)
Length = 976
Score = 31.2 bits (69), Expect = 1.2
Identities = 32/149 (21%), Positives = 61/149 (40%), Gaps = 27/149 (18%)
Frame = +2
Query: 80 KGDDKCEELNGKID------EECEDPYEALDKECDPKYEALD-------------KECLP 202
K ++ C L +++ EE + +AL K+ + + L+ +
Sbjct: 596 KSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQ 655
Query: 203 KYVEVNANFAKSVVNAKVKCEN--NQSKKSRQVVRNLEKIIFGDYDKIDKTCDGKYAELD 376
K+ E+ + K + + K+ EN + +K++ + K+ +IDK C K AE+
Sbjct: 656 KFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVKL----QKEIDKRCQHKIAEMV 711
Query: 377 KSCLKRYEDLDKLC------LPLYKEQEK 445
K DK+ L LYK +E+
Sbjct: 712 ALMEKHKHQYDKIIEERDSELGLYKSKEQ 740
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,290,448
Number of Sequences: 369166
Number of extensions: 846932
Number of successful extensions: 3486
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3289
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3449
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2534533995
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)