Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_P24
(458 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P31395|STMN1_CHICK Stathmin 34 0.14
sp|P16949|STMN1_HUMAN Stathmin (Phosphoprotein p19) (pp19) ... 33 0.30
sp|P13668|STMN1_RAT Stathmin (Phosphoprotein p19) (pp19) (O... 33 0.30
sp|P15305|DYHC_ONCMY Dynein heavy chain (DYHC) 33 0.30
sp|Q10221|YAYE_SCHPO Hypothetical protein C4H3.14c in chrom... 33 0.40
sp|Q8D2B6|Y438_WIGBR Hypothetical UPF0350 protein WIGBR4380 33 0.40
sp|Q89YY3|CLPB_BACTN Chaperone clpB 32 0.52
sp|P54227|STMN1_MOUSE Stathmin (Phosphoprotein p19) (pp19) ... 32 0.68
sp|Q9DDU0|HXABA_BRARE Homeobox protein Hox-A11a 32 0.68
sp|P93484|VSR1_PEA Vacuolar sorting receptor 1 precursor (B... 32 0.88
>sp|P31395|STMN1_CHICK Stathmin
Length = 148
Score = 34.3 bits (77), Expect = 0.14
Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 6/108 (5%)
Frame = +2
Query: 56 EYKFDLSRKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNAN 226
E+ +K D EE+ K++ EE +EA + K+ K E +KE L K +E N N
Sbjct: 34 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNN 92
Query: 227 FAKSVVDAKV-KCENNQSKKSRQVLRNLEKIIFGD--YDKIDKTCDGK 361
F+K + K E N+ + Q+ LE++ D +++ K +GK
Sbjct: 93 FSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKEGK 140
>sp|P16949|STMN1_HUMAN Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18)
(Leukemia-associated phosphoprotein p18) (pp17)
(Prosolin) (Metablastin) (Pr22 protein)
Length = 149
Score = 33.1 bits (74), Expect = 0.30
Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 4/91 (4%)
Frame = +2
Query: 56 EYKFDLSRKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNAN 226
E+ +K D EE+ K++ EE +EA + K+ K E +KE L K +E N N
Sbjct: 34 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNN 92
Query: 227 FAKSVVDAKV-KCENNQSKKSRQVLRNLEKI 316
F+K + K E N+ + Q+ LE++
Sbjct: 93 FSKMAEEKLTHKMEANKENREAQMAAKLERL 123
>sp|P13668|STMN1_RAT Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18)
(Leukemia-associated phosphoprotein p18) (pp17)
(Prosolin) (Metablastin) (Pr22 protein)
Length = 149
Score = 33.1 bits (74), Expect = 0.30
Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 4/91 (4%)
Frame = +2
Query: 56 EYKFDLSRKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNAN 226
E+ +K D EE+ K++ EE +EA + K+ K E +KE L K +E N N
Sbjct: 34 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNN 92
Query: 227 FAKSVVDAKV-KCENNQSKKSRQVLRNLEKI 316
F+K + K E N+ + Q+ LE++
Sbjct: 93 FSKMAEEKLTHKMEANKENREAQMAAKLERL 123
>sp|P15305|DYHC_ONCMY Dynein heavy chain (DYHC)
Length = 515
Score = 33.1 bits (74), Expect = 0.30
Identities = 28/154 (18%), Positives = 66/154 (42%), Gaps = 13/154 (8%)
Frame = -1
Query: 455 HNPIFLVHYIMEDTIYQDLHIV*DKI----YPILHIFHHKFYRF-YHNHQKLFFPNFLEL 291
++ + ++ Y + I +H++ I Y ILH+ + + Y H + + ++
Sbjct: 85 YSTLHVIQYSILHVIQYSIHVIQYSIHVTQYSILHVIQYSIHVIQYSIHVIQYSTHVIQY 144
Query: 290 DDFFYFDCFHI---SLLHPQLILQNLHSLLHISVNILYLMLHILDHILCLMLHTDLH--- 129
H+ S+LH ++Q ++ S++++ H++ + + ++ ++ LH
Sbjct: 145 SIHVIQYSIHVIQYSILH---VIQYSIHVIQYSIHVIQYSTHVIQYSIHVIQYSILHVIQ 201
Query: 128 --ILHQFYH*VLHIYHLPF*TNQICIRIAIYIEH 33
ILH + +LH+ Q I + Y H
Sbjct: 202 YSILHVIQYSILHVIQYSIHVIQYSIHVIQYSIH 235
Score = 32.3 bits (72), Expect = 0.52
Identities = 18/121 (14%), Positives = 56/121 (46%)
Frame = -1
Query: 446 IFLVHYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLELDDFFYFDC 267
I ++ Y + Y LH++ Y ILH+ + + ++ + + + +
Sbjct: 263 IHVIQYSIHVIQYSILHVI---QYSILHVIQYSIHVIQYSIHVIQYSIHV-----IQYSI 314
Query: 266 FHISLLHPQLILQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHILHQFYH*VLHIYH 87
H+ +I ++H ++ S++++ +H++ + + ++ ++ LH++ H + + H
Sbjct: 315 LHVIQYSIHVIQYSIH-VIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSIH 373
Query: 86 L 84
+
Sbjct: 374 V 374
Score = 31.6 bits (70), Expect = 0.88
Identities = 29/151 (19%), Positives = 60/151 (39%), Gaps = 14/151 (9%)
Frame = -1
Query: 443 FLVHYIMEDTI----YQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLELDDFFY 276
+ +H I T+ Y LH++ Y LH+ + + L + L Y
Sbjct: 38 YSIHVIQYSTLHVIQYSTLHVI---QYSTLHVIQYSTLNVIQ-YSTLHVIQYSTLHVIQY 93
Query: 275 FDCFHISLLHPQLILQNLH----SLLHI---SVNILYLMLHILD---HILCLMLHTDLHI 126
H+ +I ++H S+LH+ S++++ +H++ H++ +H +
Sbjct: 94 -SILHVIQYSIHVIQYSIHVTQYSILHVIQYSIHVIQYSIHVIQYSTHVIQYSIHVIQYS 152
Query: 125 LHQFYH*VLHIYHLPF*TNQICIRIAIYIEH 33
+H + +LH+ Q I + Y H
Sbjct: 153 IHVIQYSILHVIQYSIHVIQYSIHVIQYSTH 183
Score = 31.6 bits (70), Expect = 0.88
Identities = 28/148 (18%), Positives = 61/148 (41%), Gaps = 10/148 (6%)
Frame = -1
Query: 446 IFLVHYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLELDDFFYFDC 267
I ++ Y + I +H++ I+ I + H Y H Q + L + +
Sbjct: 241 IHVIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQY----SILHVIQY----S 292
Query: 266 FHISLLHPQLILQNLH----SLLHI---SVNILYLMLHILD---HILCLMLHTDLHILHQ 117
H+ +I ++H S+LH+ S++++ +H++ H++ +H + +H
Sbjct: 293 IHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIHVIQYSIHV 352
Query: 116 FYH*VLHIYHLPF*TNQICIRIAIYIEH 33
+ +LH+ Q I + Y H
Sbjct: 353 IQYSILHVIQYSIHVIQYSIHVIQYSIH 380
Score = 30.4 bits (67), Expect = 2.0
Identities = 25/139 (17%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
Frame = -1
Query: 446 IFLVHYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLELDDFFYFDC 267
I ++ Y + Y LH++ I+ I + H Y + + + L Y
Sbjct: 343 IHVIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQY--- 399
Query: 266 FHISLLHPQLILQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHIL----HQFYH*VL 99
S+LH +I ++H + + ++++ +H++ + + ++ ++ LH++ H + +L
Sbjct: 400 ---SILH--VIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSIL 454
Query: 98 HIYHLPF*TNQICIRIAIY 42
H+ Q I + Y
Sbjct: 455 HVIQYSIHVIQYSIHVIQY 473
Score = 30.4 bits (67), Expect = 2.0
Identities = 21/124 (16%), Positives = 60/124 (48%), Gaps = 6/124 (4%)
Frame = -1
Query: 446 IFLVHYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRFYHN--HQKLFFPNFLELDDFFYF 273
I ++ Y + Y LH++ Y ILH+ + + ++ H + + ++ +
Sbjct: 379 IHVIQYSIHVIQYSILHVI---QYSILHVIQYSIHVIQYSILHVIQYSIHVIQ----YSI 431
Query: 272 DCFHISLLHPQLILQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHI----LHQFYH* 105
S+LH +I ++H + + ++++ +H++ + + ++ ++ LH+ +H +
Sbjct: 432 HVIQYSILH--VIQYSIHVIQYSILHVIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYS 489
Query: 104 VLHI 93
+LH+
Sbjct: 490 ILHV 493
Score = 30.0 bits (66), Expect = 2.6
Identities = 28/133 (21%), Positives = 53/133 (39%), Gaps = 7/133 (5%)
Frame = -1
Query: 410 YQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLELDDFFYFDCFHISLLHPQLIL 231
Y LH++ I+ I + H Y + + + L Y H+ +I
Sbjct: 210 YSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQY--SIHVIQYSIHVIQ 267
Query: 230 QNLH----SLLHISVNILYLMLHILD---HILCLMLHTDLHILHQFYH*VLHIYHLPF*T 72
++H S+LH+ I Y +LH++ H++ +H + +H + +LH+
Sbjct: 268 YSIHVIQYSILHV---IQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSIHV 324
Query: 71 NQICIRIAIYIEH 33
Q I + Y H
Sbjct: 325 IQYSIHVIQYSIH 337
Score = 30.0 bits (66), Expect = 2.6
Identities = 21/122 (17%), Positives = 57/122 (46%), Gaps = 4/122 (3%)
Frame = -1
Query: 446 IFLVHYIMEDTIYQDLHIV*DKIYPILHIFHHKFYRFYHNHQKLFFPNFLELDDFFYFDC 267
+ ++ Y + I +H++ Y ILH+ + + ++ + + + +
Sbjct: 394 LHVIQYSILHVIQYSIHVI---QYSILHVIQYSIHVIQYSIHVIQYSILHVIQ--YSIHV 448
Query: 266 FHISLLHPQLILQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHI----LHQFYH*VL 99
S+LH +I ++H + + I Y +LH++ + + ++ ++ LH+ +H + +L
Sbjct: 449 IQYSILH--VIQYSIHVIQYSIHVIQYSILHVIQYSIHVIQYSILHVIQYSIHVIQYSIL 506
Query: 98 HI 93
H+
Sbjct: 507 HV 508
Score = 29.6 bits (65), Expect = 3.4
Identities = 21/126 (16%), Positives = 53/126 (42%), Gaps = 7/126 (5%)
Frame = -1
Query: 440 LVHYIMEDTIYQDLHIV*DKI-----YPILHIFHHKFYRF-YHNHQKLFFPNFLELD-DF 282
++ Y + Y LH++ I Y ILH+ + + Y H + + ++
Sbjct: 184 VIQYSIHVIQYSILHVIQYSILHVIQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSIHV 243
Query: 281 FYFDCFHISLLHPQLILQNLHSLLHISVNILYLMLHILDHILCLMLHTDLHILHQFYH*V 102
+ H+ +I ++H + + I Y +LH++ + + ++ +H++ H +
Sbjct: 244 IQYSILHVIQYSIHVIQYSIHVIQYSIHVIQYSILHVIQYSILHVIQYSIHVIQYSIHVI 303
Query: 101 LHIYHL 84
+ H+
Sbjct: 304 QYSIHV 309
>sp|Q10221|YAYE_SCHPO Hypothetical protein C4H3.14c in chromosome I
Length = 345
Score = 32.7 bits (73), Expect = 0.40
Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Frame = +2
Query: 113 KIDEECEDPYEALDKEC---DPKYEALDKECLPKYVEVNANFAKSVVDAKVKCENNQSKK 283
K E E+ YE L EC DP+ +A + + EV K V DAK+ ++ K
Sbjct: 181 KQKEALEEEYEELRNECLKHDPQLDAEIRTLQDTFEEVERTLTKQVSDAKIA---DKPLK 237
Query: 284 SRQVLRNLEK-IIFGDYDKIDKTCDGKYAELDKSCLKRYE-DLDKLCLPLYNEQEK 445
N EK I +K +K D Y+E + +++ E L+K + N Q +
Sbjct: 238 DSMFNSNSEKEKIMHALEKAEKDAD-IYSEFIQQYMEQLESSLEKSSTAIENAQNR 292
>sp|Q8D2B6|Y438_WIGBR Hypothetical UPF0350 protein WIGBR4380
Length = 84
Score = 32.7 bits (73), Expect = 0.40
Identities = 13/35 (37%), Positives = 20/35 (57%)
Frame = -1
Query: 371 ILHIFHHKFYRFYHNHQKLFFPNFLELDDFFYFDC 267
I++ F K + F N +K+FF N L DD + + C
Sbjct: 23 IINNFFKKEFDFLSNKEKIFFVNMLSYDDIYLYKC 57
>sp|Q89YY3|CLPB_BACTN Chaperone clpB
Length = 862
Score = 32.3 bits (72), Expect = 0.52
Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 9/115 (7%)
Frame = +2
Query: 89 DKCEELNGKIDEECEDPYEALDKECD-PKYEALDKECLPKYVEVNANFAKSVVDAKVKCE 265
++ +E++ KI ++ E EA+ +E D PK E + KE L + EV +F AK + E
Sbjct: 408 EELDEISRKI-KQLEIEREAIKRENDKPKLEIIGKE-LAELKEVEKSFK-----AKWQSE 460
Query: 266 NNQSKKSRQVLRNLEKIIF--------GDYDKIDKTCDGKYAELDKSCLKRYEDL 406
K +Q +E + F GDY K+ + GK LDK E L
Sbjct: 461 KTLMDKIQQNKVEIENLKFEAEKAEREGDYGKVAEIRYGKLQALDKEIEDTQEKL 515
>sp|P54227|STMN1_MOUSE Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18)
(Leukemia-associated phosphoprotein p18) (pp17)
(Prosolin) (Metablastin) (Pr22 protein)
(Leukemia-associated gene protein)
Length = 149
Score = 32.0 bits (71), Expect = 0.68
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Frame = +2
Query: 77 RKGDDKCEELNGKID--EECEDPYEA-LDKECDPKYEALDKECLPKYVEVNANFAKSVVD 247
+K D EE+ K++ EE +EA + K+ K E +KE L K +E N NF+K +
Sbjct: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH-EKEVLQKAIEENNNFSKMAEE 99
Query: 248 AKV-KCENNQSKKSRQVLRNLEKI 316
K E N+ + Q+ LE++
Sbjct: 100 KLTHKMEANKENREAQMAAKLERL 123
>sp|Q9DDU0|HXABA_BRARE Homeobox protein Hox-A11a
Length = 284
Score = 32.0 bits (71), Expect = 0.68
Identities = 26/97 (26%), Positives = 36/97 (37%), Gaps = 9/97 (9%)
Frame = +2
Query: 116 IDEECEDPYEALDKECDPKYEALDKECLPKYVEVNANFAKSVVDAKVKCENNQSKKSR-- 289
ID + P+ C P +++ KECLP V F K+ A +N + S
Sbjct: 68 IDPSTKWPHRGPLAHCYPSEDSVHKECLPAVTTVGEMFPKNNASAYYHSTSNTTSASNFY 127
Query: 290 -QVLRN------LEKIIFGDYDKIDKTCDGKYAELDK 379
V RN ++ Y D D YA DK
Sbjct: 128 GNVGRNGVLPQAFDQFFDTAYGGSDSVVDNDYAARDK 164
>sp|P93484|VSR1_PEA Vacuolar sorting receptor 1 precursor (BP-80) (80 kDa proaleurein
binding protein)
Length = 623
Score = 31.6 bits (70), Expect = 0.88
Identities = 15/55 (27%), Positives = 29/55 (52%)
Frame = +2
Query: 239 VVDAKVKCENNQSKKSRQVLRNLEKIIFGDYDKIDKTCDGKYAELDKSCLKRYED 403
V D +++C + K +++ ++ K + D +KIDK A+ + S LK +D
Sbjct: 301 VTDFQIRCPMKEKKYNKECANSVIKSLGLDVEKIDKCMGDPNADTENSILKEEQD 355
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,820,910
Number of Sequences: 369166
Number of extensions: 855162
Number of successful extensions: 3524
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3322
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3482
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2534533995
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)