DrC_00988
- Cluster detail
- GO Category :
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00988 (1477 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted pr... 281 4e-75 sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 280 6e-75 sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted ... 280 1e-74 sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine protei... 276 1e-73 sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L hea... 271 4e-72 sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 271 5e-72 sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted ... 268 3e-71 sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 267 5e-71 sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Catheps... 266 1e-70 sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathe... 265 3e-70
>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic protein 2) (CP-2) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 281 bits (718), Expect = 4e-75 Identities = 133/220 (60%), Positives = 165/220 (75%), Gaps = 3/220 (1%) Frame = +2 Query: 674 KLPDSVNWVKKGYVTQVKNQGQCGSCWAFSTTGSMEGQYFKNNKQLVSFSEQQLVDCSND 853 ++P +V+W +KG VT VKNQGQCGSCWAFS +G +EGQ F +L+S SEQ LVDCS+D Sbjct: 113 QIPKTVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHD 172 Query: 854 FGNQGCNGGLMDSAFQYIMQY-GLEKESDYPYTAQDGDCEYSKEKVVAHCQGFTDISHGS 1030 GNQGCNGGLMD AFQYI + GL+ E YPY A+DG C+Y E VA+ GF DI Sbjct: 173 QGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEYAVANDTGFVDIPQ-Q 231 Query: 1031 EEDLAEKLATVGPISVGIDASNPSFQFYKGGVYDEENCSSTQLDHGVLAVGYGND--EDS 1204 E+ L + +ATVGPISV +DAS+PS QFY G+Y E NCSS LDHGVL VGYG + + + Sbjct: 232 EKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKDLDHGVLVVGYGYEGTDSN 291 Query: 1205 QQNYWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYP 1324 + YWLVKNSWGK WG++GYIK++KD++N CG+AT ASYP Sbjct: 292 KDKYWLVKNSWGKEWGMDGYIKIAKDRNNHCGLATAASYP 331
Score = 214 bits (544), Expect = 7e-55
Identities = 103/169 (60%), Positives = 127/169 (75%), Gaps = 3/169 (1%)
Frame = -2
Query: 642 Q*LVDCSNDFGNQGCNGGLMDSAFQYIMQYG-LEKERDYPYTAQDGDCEYSKEKVVAHCQ 466
Q LVDCS+D GNQGCNGGLMD AFQYI + G L+ E YPY A+DG C+Y E VA+
Sbjct: 164 QNLVDCSHDQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEYAVANDT 223
Query: 465 GFTDISHGSEEDLAEKLATVGPISVGIDASNPSFQFYKAGVYDEENCSSTQLDHGVLAVG 286
GF DI E+ L + +ATVGPISV +DAS+PS QFY +G+Y E NCSS LDHGVL VG
Sbjct: 224 GFVDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKDLDHGVLVVG 282
Query: 285 YGND--EDSQQNYWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYP 145
YG + + ++ YWLVKNSWGK WG++GYIK++KD++N CG+AT ASYP
Sbjct: 283 YGYEGTDSNKDKYWLVKNSWGKEWGMDGYIKIAKDRNNHCGLATAASYP 331
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U) Length = 334 Score = 280 bits (717), Expect = 6e-75 Identities = 135/221 (61%), Positives = 161/221 (72%), Gaps = 3/221 (1%) Frame = +2 Query: 677 LPDSVNWVKKGYVTQVKNQGQCGSCWAFSTTGSMEGQYFKNNKQLVSFSEQQLVDCSNDF 856 LP SV+W KKGYVT VKNQ QCGSCWAFS TG++EGQ F+ +LVS SEQ LVDCS Sbjct: 114 LPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ 173 Query: 857 GNQGCNGGLMDSAFQYIMQY-GLEKESDYPYTAQDGDCEYSKEKVVAHCQGFTDISHGSE 1033 GNQGCNGG M AFQY+ + GL+ E YPY A D C+Y E VA+ GFT ++ G E Sbjct: 174 GNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKE 233 Query: 1034 EDLAEKLATVGPISVGIDASNPSFQFYKGGVYDEENCSSTQLDHGVLAVGYGNDEDSQQN 1213 + L + +ATVGPISV +DA + SFQFYK G+Y E +CSS LDHGVL VGYG + + N Sbjct: 234 KALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNN 293 Query: 1214 --YWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYPNM 1330 YWLVKNSWG WG NGY+K++KDK+N CGIAT ASYPN+ Sbjct: 294 SKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
Score = 206 bits (523), Expect = 2e-52
Identities = 100/171 (58%), Positives = 122/171 (71%), Gaps = 3/171 (1%)
Frame = -2
Query: 642 Q*LVDCSNDFGNQGCNGGLMDSAFQYIMQYG-LEKERDYPYTAQDGDCEYSKEKVVAHCQ 466
Q LVDCS GNQGCNGG M AFQY+ + G L+ E YPY A D C+Y E VA+
Sbjct: 164 QNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDT 223
Query: 465 GFTDISHGSEEDLAEKLATVGPISVGIDASNPSFQFYKAGVYDEENCSSTQLDHGVLAVG 286
GFT ++ G E+ L + +ATVGPISV +DA + SFQFYK+G+Y E +CSS LDHGVL VG
Sbjct: 224 GFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVG 283
Query: 285 YGNDEDSQQN--YWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYPNM 139
YG + + N YWLVKNSWG WG NGY+K++KDK+N CGIAT ASYPN+
Sbjct: 284 YGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
>sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted protein) (MEP) (p39 cysteine proteinase) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 280 bits (715), Expect = 1e-74 Identities = 137/220 (62%), Positives = 163/220 (74%), Gaps = 3/220 (1%) Frame = +2 Query: 674 KLPDSVNWVKKGYVTQVKNQGQCGSCWAFSTTGSMEGQYFKNNKQLVSFSEQQLVDCSND 853 K+P SV+W +KG VT VKNQGQCGSCWAFS +G +EGQ F +L+S SEQ LVDCS+ Sbjct: 113 KIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHA 172 Query: 854 FGNQGCNGGLMDSAFQYIMQY-GLEKESDYPYTAQDGDCEYSKEKVVAHCQGFTDISHGS 1030 GNQGCNGGLMD AFQYI + GL+ E YPY A+DG C+Y E VA+ GF DI Sbjct: 173 QGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQ-Q 231 Query: 1031 EEDLAEKLATVGPISVGIDASNPSFQFYKGGVYDEENCSSTQLDHGVLAVGYGND-EDSQ 1207 E+ L + +ATVGPISV +DAS+PS QFY G+Y E NCSS LDHGVL VGYG + DS Sbjct: 232 EKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSN 291 Query: 1208 QN-YWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYP 1324 +N YWLVKNSWG WG+ GYIK++KD+DN CG+AT ASYP Sbjct: 292 KNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYP 331
Score = 210 bits (534), Expect = 1e-53
Identities = 105/169 (62%), Positives = 125/169 (73%), Gaps = 3/169 (1%)
Frame = -2
Query: 642 Q*LVDCSNDFGNQGCNGGLMDSAFQYIMQYG-LEKERDYPYTAQDGDCEYSKEKVVAHCQ 466
Q LVDCS+ GNQGCNGGLMD AFQYI + G L+ E YPY A+DG C+Y E VA+
Sbjct: 164 QNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDT 223
Query: 465 GFTDISHGSEEDLAEKLATVGPISVGIDASNPSFQFYKAGVYDEENCSSTQLDHGVLAVG 286
GF DI E+ L + +ATVGPISV +DAS+PS QFY +G+Y E NCSS LDHGVL VG
Sbjct: 224 GFVDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVG 282
Query: 285 YGND-EDSQQN-YWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYP 145
YG + DS +N YWLVKNSWG WG+ GYIK++KD+DN CG+AT ASYP
Sbjct: 283 YGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYP 331
>sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine proteinase 1) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 341 Score = 276 bits (705), Expect = 1e-73 Identities = 130/217 (59%), Positives = 163/217 (75%), Gaps = 1/217 (0%) Frame = +2 Query: 677 LPDSVNWVKKGYVTQVKNQGQCGSCWAFSTTGSMEGQYFKNNKQLVSFSEQQLVDCSNDF 856 LP SV+W KG VT VK+QG CGSCWAFS+TG++EGQ+F+ + LVS SEQ LVDCS + Sbjct: 124 LPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKY 183 Query: 857 GNQGCNGGLMDSAFQYIMQY-GLEKESDYPYTAQDGDCEYSKEKVVAHCQGFTDISHGSE 1033 GN GCNGGLMD+AF+YI G++ E YPY A D C ++K V A +GFTDI G E Sbjct: 184 GNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDE 243 Query: 1034 EDLAEKLATVGPISVGIDASNPSFQFYKGGVYDEENCSSTQLDHGVLAVGYGNDEDSQQN 1213 + +AE +ATVGP+SV IDAS+ SFQFY GVY+E C + LDHGVL VG+G DE S ++ Sbjct: 244 KKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDE-SGED 302 Query: 1214 YWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYP 1324 YWLVKNSWG +WG G+IKM ++K+NQCGIA+ +SYP Sbjct: 303 YWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYP 339
Score = 207 bits (528), Expect = 5e-53
Identities = 98/167 (58%), Positives = 124/167 (74%), Gaps = 1/167 (0%)
Frame = -2
Query: 642 Q*LVDCSNDFGNQGCNGGLMDSAFQYIMQYG-LEKERDYPYTAQDGDCEYSKEKVVAHCQ 466
Q LVDCS +GN GCNGGLMD+AF+YI G ++ E+ YPY A D C ++K V A +
Sbjct: 174 QNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDR 233
Query: 465 GFTDISHGSEEDLAEKLATVGPISVGIDASNPSFQFYKAGVYDEENCSSTQLDHGVLAVG 286
GFTDI G E+ +AE +ATVGP+SV IDAS+ SFQFY GVY+E C + LDHGVL VG
Sbjct: 234 GFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVG 293
Query: 285 YGNDEDSQQNYWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYP 145
+G DE S ++YWLVKNSWG +WG G+IKM ++K+NQCGIA+ +SYP
Sbjct: 294 FGTDE-SGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYP 339
>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 217 Score = 271 bits (693), Expect = 4e-72 Identities = 132/219 (60%), Positives = 156/219 (71%), Gaps = 1/219 (0%) Frame = +2 Query: 677 LPDSVNWVKKGYVTQVKNQGQCGSCWAFSTTGSMEGQYFKNNKQLVSFSEQQLVDCSNDF 856 +P SV+W KKGYVT VKNQGQCGSCWAFS TG++EGQ F+ +LVS SEQ LVD S Sbjct: 1 VPKSVDWTKKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDSSRPQ 60 Query: 857 GNQGCNGGLMDSAFQYIMQY-GLEKESDYPYTAQDGDCEYSKEKVVAHCQGFTDISHGSE 1033 GNQGCNGGLMD+AFQYI + GL+ E YPY A D C Y E A GF DI E Sbjct: 61 GNQGCNGGLMDNAFQYIKENGGLDSEESYPYEATDTSCNYKPEYSAAKDTGFVDIPQ-RE 119 Query: 1034 EDLAEKLATVGPISVGIDASNPSFQFYKGGVYDEENCSSTQLDHGVLAVGYGNDEDSQQN 1213 + L + +ATVGPISV IDA + SFQFYK G+Y + +CSS LDHGVL VGYG E + Sbjct: 120 KALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYG-FEGTNNK 178 Query: 1214 YWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYPNM 1330 +W+VKNSWG WG GY+KM+KD++N CGIAT ASYP + Sbjct: 179 FWIVKNSWGPEWGNKGYVKMAKDQNNHCGIATAASYPTV 217
Score = 193 bits (491), Expect = 9e-49
Identities = 97/169 (57%), Positives = 116/169 (68%), Gaps = 1/169 (0%)
Frame = -2
Query: 642 Q*LVDCSNDFGNQGCNGGLMDSAFQYIMQYG-LEKERDYPYTAQDGDCEYSKEKVVAHCQ 466
Q LVD S GNQGCNGGLMD+AFQYI + G L+ E YPY A D C Y E A
Sbjct: 51 QNLVDSSRPQGNQGCNGGLMDNAFQYIKENGGLDSEESYPYEATDTSCNYKPEYSAAKDT 110
Query: 465 GFTDISHGSEEDLAEKLATVGPISVGIDASNPSFQFYKAGVYDEENCSSTQLDHGVLAVG 286
GF DI E+ L + +ATVGPISV IDA + SFQFYK+G+Y + +CSS LDHGVL VG
Sbjct: 111 GFVDIPQ-REKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVG 169
Query: 285 YGNDEDSQQNYWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYPNM 139
YG E + +W+VKNSWG WG GY+KM+KD++N CGIAT ASYP +
Sbjct: 170 YG-FEGTNNKFWIVKNSWGPEWGNKGYVKMAKDQNNHCGIATAASYPTV 217
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 271 bits (692), Expect = 5e-72 Identities = 135/222 (60%), Positives = 158/222 (71%), Gaps = 4/222 (1%) Frame = +2 Query: 677 LPDSVNWVKKGYVTQVKNQGQCGSCWAFSTTGSMEGQYFKNNKQLVSFSEQQLVDCSNDF 856 +P SV+W KKGYVT VKNQGQCGSCWAFS TG++EGQ F+ +LVS SEQ LVDCS Sbjct: 114 VPKSVDWTKKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQ 173 Query: 857 GNQGCNGGLMDSAFQYIMQY-GLEKESDYPYTAQD-GDCEYSKEKVVAHCQGFTDISHGS 1030 GNQGCNGGLMD+AFQYI GL+ E YPY A D C Y E A+ GF DI Sbjct: 174 GNQGCNGGLMDNAFQYIKDNGGLDSEESYPYLATDTNSCNYKPECSAANDTGFVDIPQ-R 232 Query: 1031 EEDLAEKLATVGPISVGIDASNPSFQFYKGGVYDEENCSSTQLDHGVLAVGYG-NDEDSQ 1207 E+ L + +ATVGPISV IDA + SFQFYK G+Y + +CS LDHGVL VGYG DS Sbjct: 233 EKALMKAVATVGPISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSN 292 Query: 1208 QN-YWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYPNM 1330 N +W+VKNSWG WG NGY+KM+KD++N CGIAT ASYP + Sbjct: 293 NNKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 334
Score = 193 bits (490), Expect = 1e-48
Identities = 100/172 (58%), Positives = 119/172 (69%), Gaps = 4/172 (2%)
Frame = -2
Query: 642 Q*LVDCSNDFGNQGCNGGLMDSAFQYIMQYG-LEKERDYPYTAQD-GDCEYSKEKVVAHC 469
Q LVDCS GNQGCNGGLMD+AFQYI G L+ E YPY A D C Y E A+
Sbjct: 164 QNLVDCSRAQGNQGCNGGLMDNAFQYIKDNGGLDSEESYPYLATDTNSCNYKPECSAAND 223
Query: 468 QGFTDISHGSEEDLAEKLATVGPISVGIDASNPSFQFYKAGVYDEENCSSTQLDHGVLAV 289
GF DI E+ L + +ATVGPISV IDA + SFQFYK+G+Y + +CS LDHGVL V
Sbjct: 224 TGFVDIPQ-REKALMKAVATVGPISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVV 282
Query: 288 GYGND-EDSQQN-YWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYPNM 139
GYG + DS N +W+VKNSWG WG NGY+KM+KD++N CGIAT ASYP +
Sbjct: 283 GYGFEGTDSNNNKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 334
>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 333 Score = 268 bits (685), Expect = 3e-71 Identities = 128/220 (58%), Positives = 158/220 (71%), Gaps = 3/220 (1%) Frame = +2 Query: 680 PDSVNWVKKGYVTQVKNQGQCGSCWAFSTTGSMEGQYFKNNKQLVSFSEQQLVDCSNDFG 859 P SV+W +KGYVT VKNQGQCGSCWAFS TG++EGQ F+ +L+S SEQ LVDCS G Sbjct: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 Query: 860 NQGCNGGLMDSAFQYIMQY-GLEKESDYPYTAQDGDCEYSKEKVVAHCQGFTDISHGSEE 1036 N+GCNGGLMD AFQY+ GL+ E YPY A + C+Y+ + VA+ GF DI E+ Sbjct: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEK 233 Query: 1037 DLAEKLATVGPISVGIDASNPSFQFYKGGVYDEENCSSTQLDHGVLAVGYG--NDEDSQQ 1210 L + +ATVGPISV IDA + SF FYK G+Y E +CSS +DHGVL VGYG + E Sbjct: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 Query: 1211 NYWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYPNM 1330 YWLVKNSWG+ WG+ GY+KM+KD+ N CGIA+ ASYP + Sbjct: 294 KYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
Score = 194 bits (493), Expect = 5e-49
Identities = 95/171 (55%), Positives = 118/171 (69%), Gaps = 3/171 (1%)
Frame = -2
Query: 642 Q*LVDCSNDFGNQGCNGGLMDSAFQYIMQYG-LEKERDYPYTAQDGDCEYSKEKVVAHCQ 466
Q LVDCS GN+GCNGGLMD AFQY+ G L+ E YPY A + C+Y+ + VA+
Sbjct: 164 QNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDT 223
Query: 465 GFTDISHGSEEDLAEKLATVGPISVGIDASNPSFQFYKAGVYDEENCSSTQLDHGVLAVG 286
GF DI E+ L + +ATVGPISV IDA + SF FYK G+Y E +CSS +DHGVL VG
Sbjct: 224 GFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVG 282
Query: 285 YG--NDEDSQQNYWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYPNM 139
YG + E YWLVKNSWG+ WG+ GY+KM+KD+ N CGIA+ ASYP +
Sbjct: 283 YGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 333 Score = 267 bits (683), Expect = 5e-71 Identities = 128/222 (57%), Positives = 160/222 (72%), Gaps = 3/222 (1%) Frame = +2 Query: 674 KLPDSVNWVKKGYVTQVKNQGQCGSCWAFSTTGSMEGQYFKNNKQLVSFSEQQLVDCSND 853 ++P SV+W +KGYVT VKNQGQCGSCWAFS TG++EGQ F+ +LVS SEQ LVDCS Sbjct: 113 EIPKSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRA 172 Query: 854 FGNQGCNGGLMDSAFQYIMQY-GLEKESDYPYTAQDGD-CEYSKEKVVAHCQGFTDISHG 1027 GN+GCNGGLMD+AF+Y+ GL+ E YPY +D + C Y E A+ GF D+ Sbjct: 173 QGNEGCNGGLMDNAFRYVKDNGGLDSEESYPYLGRDTETCNYKPECSAANDTGFVDLPQ- 231 Query: 1028 SEEDLAEKLATVGPISVGIDASNPSFQFYKGGVYDEENCSSTQLDHGVLAVGYG-NDEDS 1204 E+ L + +AT+GPISV IDA + SFQFYK G+Y + +CSS LDHGVL VGYG DS Sbjct: 232 REKALMKAVATLGPISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDS 291 Query: 1205 QQNYWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYPNM 1330 +W+VKNSWG WG NGY+KM+KD++N CGIAT ASYP + Sbjct: 292 NNKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 333
Score = 191 bits (486), Expect = 4e-48
Identities = 94/171 (54%), Positives = 119/171 (69%), Gaps = 3/171 (1%)
Frame = -2
Query: 642 Q*LVDCSNDFGNQGCNGGLMDSAFQYIMQYG-LEKERDYPYTAQDGD-CEYSKEKVVAHC 469
Q LVDCS GN+GCNGGLMD+AF+Y+ G L+ E YPY +D + C Y E A+
Sbjct: 164 QNLVDCSRAQGNEGCNGGLMDNAFRYVKDNGGLDSEESYPYLGRDTETCNYKPECSAAND 223
Query: 468 QGFTDISHGSEEDLAEKLATVGPISVGIDASNPSFQFYKAGVYDEENCSSTQLDHGVLAV 289
GF D+ E+ L + +AT+GPISV IDA + SFQFYK+G+Y + +CSS LDHGVL V
Sbjct: 224 TGFVDLPQ-REKALMKAVATLGPISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVV 282
Query: 288 GYG-NDEDSQQNYWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYPNM 139
GYG DS +W+VKNSWG WG NGY+KM+KD++N CGIAT ASYP +
Sbjct: 283 GYGFEGTDSNNKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 333
>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 266 bits (679), Expect = 1e-70 Identities = 128/223 (57%), Positives = 159/223 (71%), Gaps = 4/223 (1%) Frame = +2 Query: 674 KLPDSVNWVKKGYVTQVKNQGQCGSCWAFSTTGSMEGQYFKNNKQLVSFSEQQLVDCSND 853 ++P SV+W +KGYVT VKNQGQCGSCWAFS TG++EGQ F+ +LVS SEQ LVDCS Sbjct: 113 EVPKSVDWREKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRP 172 Query: 854 FGNQGCNGGLMDSAFQYIMQY-GLEKESDYPYTAQD-GDCEYSKEKVVAHCQGFTDISHG 1027 GNQGCNGGLMD+AFQY+ GL+ E YPY ++ C Y E A+ GF DI Sbjct: 173 QGNQGCNGGLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQ- 231 Query: 1028 SEEDLAEKLATVGPISVGIDASNPSFQFYKGGVYDEENCSSTQLDHGVLAVGYG--NDED 1201 E+ L + +ATVGPISV IDA + SFQFYK G+Y + +CSS LDHGVL VGYG + Sbjct: 232 REKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDS 291 Query: 1202 SQQNYWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYPNM 1330 + +W+VKNSWG WG NGY+KM+KD++N CGI+T ASYP + Sbjct: 292 NSSKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGISTAASYPTV 334
Score = 190 bits (483), Expect = 8e-48
Identities = 94/172 (54%), Positives = 118/172 (68%), Gaps = 4/172 (2%)
Frame = -2
Query: 642 Q*LVDCSNDFGNQGCNGGLMDSAFQYIMQYG-LEKERDYPYTAQD-GDCEYSKEKVVAHC 469
Q LVDCS GNQGCNGGLMD+AFQY+ G L+ E YPY ++ C Y E A+
Sbjct: 164 QNLVDCSRPQGNQGCNGGLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAAND 223
Query: 468 QGFTDISHGSEEDLAEKLATVGPISVGIDASNPSFQFYKAGVYDEENCSSTQLDHGVLAV 289
GF DI E+ L + +ATVGPISV IDA + SFQFYK+G+Y + +CSS LDHGVL V
Sbjct: 224 TGFVDIPQ-REKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVV 282
Query: 288 GYG--NDEDSQQNYWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYPNM 139
GYG + + +W+VKNSWG WG NGY+KM+KD++N CGI+T ASYP +
Sbjct: 283 GYGFEGTDSNSSKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGISTAASYPTV 334
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 339 Score = 265 bits (677), Expect = 3e-70 Identities = 124/219 (56%), Positives = 157/219 (71%), Gaps = 1/219 (0%) Frame = +2 Query: 677 LPDSVNWVKKGYVTQVKNQGQCGSCWAFSTTGSMEGQYFKNNKQLVSFSEQQLVDCSNDF 856 +P SV+W + G VT VK+QG CGSCWAFS+TG++EGQ+F+ LVS SEQ LVDCS + Sbjct: 122 VPKSVDWREHGAVTGVKDQGHCGSCWAFSSTGALEGQHFRKAGVLVSLSEQNLVDCSTKY 181 Query: 857 GNQGCNGGLMDSAFQYIMQY-GLEKESDYPYTAQDGDCEYSKEKVVAHCQGFTDISHGSE 1033 GN GCNGGLMD+AF+YI G++ E YPY D C ++K + A GF DI G E Sbjct: 182 GNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEGIDDSCHFNKATIGATDTGFVDIPEGDE 241 Query: 1034 EDLAEKLATVGPISVGIDASNPSFQFYKGGVYDEENCSSTQLDHGVLAVGYGNDEDSQQN 1213 E + + +AT+GP+SV IDAS+ SFQ Y GVY+E C LDHGVL VGYG DE S + Sbjct: 242 EKMKKAVATMGPVSVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVGYGTDE-SGMD 300 Query: 1214 YWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYPNM 1330 YWLVKNSWG +WG GYIKM+++++NQCGIAT +SYP + Sbjct: 301 YWLVKNSWGTTWGEQGYIKMARNQNNQCGIATASSYPTV 339
Score = 201 bits (511), Expect = 4e-51
Identities = 94/169 (55%), Positives = 119/169 (70%), Gaps = 1/169 (0%)
Frame = -2
Query: 642 Q*LVDCSNDFGNQGCNGGLMDSAFQYIMQYG-LEKERDYPYTAQDGDCEYSKEKVVAHCQ 466
Q LVDCS +GN GCNGGLMD+AF+YI G ++ E+ YPY D C ++K + A
Sbjct: 172 QNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEGIDDSCHFNKATIGATDT 231
Query: 465 GFTDISHGSEEDLAEKLATVGPISVGIDASNPSFQFYKAGVYDEENCSSTQLDHGVLAVG 286
GF DI G EE + + +AT+GP+SV IDAS+ SFQ Y GVY+E C LDHGVL VG
Sbjct: 232 GFVDIPEGDEEKMKKAVATMGPVSVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVG 291
Query: 285 YGNDEDSQQNYWLVKNSWGKSWGINGYIKMSKDKDNQCGIATMASYPNM 139
YG DE S +YWLVKNSWG +WG GYIKM+++++NQCGIAT +SYP +
Sbjct: 292 YGTDE-SGMDYWLVKNSWGTTWGEQGYIKMARNQNNQCGIATASSYPTV 339
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 173,644,184
Number of Sequences: 369166
Number of extensions: 3777535
Number of successful extensions: 10947
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6040
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9890
length of database: 68,354,980
effective HSP length: 115
effective length of database: 47,110,455
effective search space used: 17713531080
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
