Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_018_J19 (175 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted pr... 72 4e-13 sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted ... 72 5e-13 sp|Q94714|CATL1_PARTE Cathepsin L1 precursor 71 7e-13 sp|Q24940|CATLP_FASHE Cathepsin L-like proteinase precursor 70 1e-12 sp||P09648_1 [Segment 1 of 2] Cathepsin L [Contains: Cathep... 68 7e-12 sp|Q10716|CYSP1_MAIZE Cysteine proteinase 1 precursor 67 1e-11 sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L hea... 66 2e-11 sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine protei... 65 4e-11 sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted ... 63 2e-10 sp|Q8HY81|CATS_CANFA Cathepsin S precursor 63 2e-10
>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic protein 2) (CP-2) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 72.0 bits (175), Expect = 4e-13 Identities = 34/55 (61%), Positives = 39/55 (70%), Gaps = 1/55 (1%) Frame = +3 Query: 3 GNQGCNGGLMDSAFQYIMQYG-LEKERDYPYTAQDGDCEYSKEKVVAHCQGFTDI 164 GNQGCNGGLMD AFQYI + G L+ E YPY A+DG C+Y E VA+ GF DI Sbjct: 174 GNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEYAVANDTGFVDI 228
>sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted protein) (MEP) (p39 cysteine proteinase) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 71.6 bits (174), Expect = 5e-13 Identities = 34/55 (61%), Positives = 39/55 (70%), Gaps = 1/55 (1%) Frame = +3 Query: 3 GNQGCNGGLMDSAFQYIMQYG-LEKERDYPYTAQDGDCEYSKEKVVAHCQGFTDI 164 GNQGCNGGLMD AFQYI + G L+ E YPY A+DG C+Y E VA+ GF DI Sbjct: 174 GNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDI 228
>sp|Q94714|CATL1_PARTE Cathepsin L1 precursor Length = 314 Score = 71.2 bits (173), Expect = 7e-13 Identities = 30/53 (56%), Positives = 38/53 (71%) Frame = +3 Query: 6 NQGCNGGLMDSAFQYIMQYGLEKERDYPYTAQDGDCEYSKEKVVAHCQGFTDI 164 N GCNGG MDSAF+Y+ GL + +DYPYTA+DG C+ S ++ H QGF DI Sbjct: 172 NDGCNGGWMDSAFEYVADNGLAEAKDYPYTAKDGTCKTSVKRPYTHVQGFKDI 224
>sp|Q24940|CATLP_FASHE Cathepsin L-like proteinase precursor Length = 326 Score = 70.5 bits (171), Expect = 1e-12 Identities = 29/57 (50%), Positives = 40/57 (70%) Frame = +3 Query: 3 GNQGCNGGLMDSAFQYIMQYGLEKERDYPYTAQDGDCEYSKEKVVAHCQGFTDISHG 173 GN GC+GGLM++A+QY+ Q+GLE E YPYTA +G C Y+K+ VA G+ + G Sbjct: 168 GNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSG 224
>sp||P09648_1 [Segment 1 of 2] Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 176 Score = 67.8 bits (164), Expect = 7e-12 Identities = 33/59 (55%), Positives = 38/59 (64%), Gaps = 2/59 (3%) Frame = +3 Query: 3 GNQGCNGGLMDSAFQYIMQY-GLEKERDYPYTAQDG-DCEYSKEKVVAHCQGFTDISHG 173 GNQGCNGGLMD AFQY+ G++ E YPYTA+D DC Y E A+ GF DI G Sbjct: 61 GNQGCNGGLMDQAFQYVQDNGGIDSEESYPYTAKDDEDCRYKAEYNAANDTGFVDIPQG 119
>sp|Q10716|CYSP1_MAIZE Cysteine proteinase 1 precursor Length = 371 Score = 67.0 bits (162), Expect = 1e-11 Identities = 29/55 (52%), Positives = 39/55 (70%), Gaps = 1/55 (1%) Frame = +3 Query: 6 NQGCNGGLMDSAFQYIMQYG-LEKERDYPYTAQDGDCEYSKEKVVAHCQGFTDIS 167 + GCNGGLM +AF Y+ + G LE E+DYPYT DG C++ K K+VA Q F+ +S Sbjct: 205 DSGCNGGLMTTAFSYLQKAGGLESEKDYPYTGSDGKCKFDKSKIVASVQNFSVVS 259
>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 217 Score = 66.2 bits (160), Expect = 2e-11 Identities = 32/55 (58%), Positives = 35/55 (63%), Gaps = 1/55 (1%) Frame = +3 Query: 3 GNQGCNGGLMDSAFQYIMQY-GLEKERDYPYTAQDGDCEYSKEKVVAHCQGFTDI 164 GNQGCNGGLMD+AFQYI + GL+ E YPY A D C Y E A GF DI Sbjct: 61 GNQGCNGGLMDNAFQYIKENGGLDSEESYPYEATDTSCNYKPEYSAAKDTGFVDI 115
>sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine proteinase 1) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 341 Score = 65.5 bits (158), Expect = 4e-11 Identities = 31/58 (53%), Positives = 39/58 (67%), Gaps = 1/58 (1%) Frame = +3 Query: 3 GNQGCNGGLMDSAFQYIMQYG-LEKERDYPYTAQDGDCEYSKEKVVAHCQGFTDISHG 173 GN GCNGGLMD+AF+YI G ++ E+ YPY A D C ++K V A +GFTDI G Sbjct: 184 GNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQG 241
>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 333 Score = 63.2 bits (152), Expect = 2e-10 Identities = 29/55 (52%), Positives = 37/55 (67%), Gaps = 1/55 (1%) Frame = +3 Query: 3 GNQGCNGGLMDSAFQYIMQY-GLEKERDYPYTAQDGDCEYSKEKVVAHCQGFTDI 164 GN+GCNGGLMD AFQY+ GL+ E YPY A + C+Y+ + VA+ GF DI Sbjct: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI 228
>sp|Q8HY81|CATS_CANFA Cathepsin S precursor Length = 331 Score = 63.2 bits (152), Expect = 2e-10 Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 1/58 (1%) Frame = +3 Query: 3 GNQGCNGGLMDSAFQYIMQY-GLEKERDYPYTAQDGDCEYSKEKVVAHCQGFTDISHG 173 GN+GCNGG M +AFQYI+ G++ E YPY A +G C Y +K A C +T++ G Sbjct: 176 GNKGCNGGFMTTAFQYIIDNNGIDSEASYPYKAMNGKCRYDSKKRAATCSKYTELPFG 233
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,408,265 Number of Sequences: 369166 Number of extensions: 360157 Number of successful extensions: 1296 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1193 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1204 length of database: 68,354,980 effective HSP length: 30 effective length of database: 62,812,930 effective search space used: 1695949110 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)