Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00891 (984 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9QZA2|PDC6I_RAT Programmed cell death 6-interacting pro... 124 5e-28 sp|Q8WUM4|PDC6I_HUMAN Programmed cell death 6-interacting p... 120 6e-27 sp|Q9WU78|PDC6I_MOUSE Programmed cell death 6-interacting p... 120 6e-27 sp|P34552|PQN58_CAEEL Protein pqn-58 (Protein YNK1) 111 3e-24 sp|Q9W6C5|PDC6I_XENLA Programmed cell death 6-interacting p... 109 1e-23 sp|P79020|PALA_EMENI pH-response regulator protein palA/RIM20 58 5e-08 sp|Q5KU05|PALA_ASPOR pH-response regulator protein palA/RIM20 58 5e-08 sp|Q51NJ3|PALA_MAGGR pH-response regulator protein palA/RIM20 47 6e-05 sp|Q7S532|PALA_NEUCR pH-response regulator protein palA/rim-20 45 2e-04 sp|Q9H3S7|PTN23_HUMAN Tyrosine-protein phosphatase, non-rec... 44 0.001
>sp|Q9QZA2|PDC6I_RAT Programmed cell death 6-interacting protein (ALG-2 interacting protein 1) Length = 401 Score = 124 bits (310), Expect = 5e-28 Identities = 74/207 (35%), Positives = 116/207 (56%), Gaps = 3/207 (1%) Frame = +2 Query: 26 VKEVLRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQDQFMEEQLNK 205 V VL++L + ++++K R L L ++ L A++ D +N++ +L++ Sbjct: 81 VVNVLKSLLSNLDEIKKEREGLENDLKSVNFDMTSKFLT-ALAQDGVINEEALSVTELDR 139 Query: 206 LLTPLRQEVRESLNVQEKLCAQLQ---QKCSLLNPNESSGANRGSVISALLLAFDKFHEL 376 + L +V+ESL QE L +Q Q+ S + + S + R V+ L A+D F EL Sbjct: 140 IYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNSEASLREEVLKNLATAYDNFVEL 199 Query: 377 KSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDLQTSIVREKADANPIRTS 556 +NL+EG KFY +LTEIL++FQNK D FARKTE+DEL+KDLQ SI RE + + + Sbjct: 200 VANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPPPA 259 Query: 557 NIKATSGGTEVSSQPPVQNEVPARPLP 637 + +GG + P + PA+P P Sbjct: 260 YQSSPAGGHATAPTPAPRTMPPAKPQP 286
>sp|Q8WUM4|PDC6I_HUMAN Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2 interacting protein 1) (Hp95) Length = 868 Score = 120 bits (301), Expect = 6e-27 Identities = 77/215 (35%), Positives = 118/215 (54%), Gaps = 11/215 (5%) Frame = +2 Query: 26 VKEVLRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQDQFMEEQLNK 205 V VL++L + ++++K R L L ++ L A++ D +N++ +L++ Sbjct: 548 VVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLT-ALAQDGVINEEALSVTELDR 606 Query: 206 LLTPLRQEVRESLNVQEKLCAQLQ---QKCSLLNPNESSGANRGSVISALLLAFDKFHEL 376 + L +V+ESL QE L +Q Q+ S + + + R V+ L A+D F EL Sbjct: 607 VYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVEL 666 Query: 377 KSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDLQTSIVREKADANPIRTS 556 +NL+EG KFY +LTEIL++FQNK D FARKTE+DEL+KDLQ SI RE + A I T Sbjct: 667 VANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPS-APSIPTP 725 Query: 557 NIKATSGGTEV--------SSQPPVQNEVPARPLP 637 +++ G + PP + + PARP P Sbjct: 726 AYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPP 760
>sp|Q9WU78|PDC6I_MOUSE Programmed cell death 6-interacting protein (ALG-2 interacting protein X) (ALG-2 interacting protein 1) (E2F1-inducible protein) (Eig2) Length = 869 Score = 120 bits (301), Expect = 6e-27 Identities = 74/208 (35%), Positives = 113/208 (54%), Gaps = 4/208 (1%) Frame = +2 Query: 26 VKEVLRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQDQFMEEQLNK 205 V VL++L + ++++K R +L L ++ L A++ D +N++ +L++ Sbjct: 548 VVSVLKSLLSNLDEIKKERESLENDLKSVNFDMTSKFLT-ALAQDGVINEEALSVTELDR 606 Query: 206 LLTPLRQEVRESLNVQEKLCAQLQ---QKCSLLNPNESSGANRGSVISALLLAFDKFHEL 376 + L +V+ESL QE L +Q Q+ S + + + R V+ L A+D F EL Sbjct: 607 IYGGLTSKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVEL 666 Query: 377 KSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDLQTSIVRE-KADANPIRT 553 +NL+EG KFY +LTEIL++FQNK D FARKTE+DEL+KDLQ SI RE A + P Sbjct: 667 VANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPPPA 726 Query: 554 SNIKATSGGTEVSSQPPVQNEVPARPLP 637 +G P + PA+P P Sbjct: 727 YQSSPAAGHAAAPPTPAPRTMPPAKPQP 754
>sp|P34552|PQN58_CAEEL Protein pqn-58 (Protein YNK1) Length = 861 Score = 111 bits (278), Expect = 3e-24 Identities = 64/173 (36%), Positives = 104/173 (60%), Gaps = 3/173 (1%) Frame = +2 Query: 11 GNSDSVKEVLRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQDQFME 190 G +D+V++ LR ++ ++ R L ++L N L KA++++ +N++ + Sbjct: 550 GETDTVRQ-LRQFMSQWNEVTTDRELLEKELKNTNCDIANDFL-KAMAENQLINEEHISK 607 Query: 191 EQLNKLLTPLRQEVRESLNVQEKLCAQLQQKCSLLNPNE---SSGANRGSVISALLLAFD 361 E++ ++ L++ V+ SL+ QE L Q+Q + + S+GA R ++ L A D Sbjct: 608 EKIAQIFGDLKRRVQSSLDTQETLMNQIQAANNTFTGEKTGSSTGAERERILKMLAQASD 667 Query: 362 KFHELKSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDLQTSIV 520 + ELK+NLEEG KFY DLT IL++ Q KV DF FAR+TEK++LM+ LQ SIV Sbjct: 668 AYVELKANLEEGTKFYNDLTPILVRLQQKVSDFAFARQTEKEDLMRQLQLSIV 720
>sp|Q9W6C5|PDC6I_XENLA Programmed cell death 6-interacting protein (Signal transduction protein Xp95) Length = 867 Score = 109 bits (273), Expect = 1e-23 Identities = 75/222 (33%), Positives = 115/222 (51%), Gaps = 20/222 (9%) Frame = +2 Query: 26 VKEVLRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQDQFMEEQLNK 205 V VL++L N+++ +K R L + ++ L A++ D +N++ +L++ Sbjct: 547 VVTVLKSLLNKLDDMKKEREQLENDIKSVNFDMTTKFLT-ALAQDGAVNEEAISVTELDQ 605 Query: 206 LLTPLRQEVRESLNVQEKLCAQLQ---QKCSLLNPNESSGANRGSVISALLLAFDKFHEL 376 + +V+E+L QE L +Q Q+ S + + S R V+ L + D + EL Sbjct: 606 IYGSYTYKVQENLKKQEDLLNNIQSAHQEFSKMKQSNSEANLREEVLKNLAVGHDNYIEL 665 Query: 377 KSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDLQTSIVRE---------- 526 +NL+EG KFY DLT+ILLKFQ K D FARKTE+DEL+KD+Q SI RE Sbjct: 666 VANLKEGTKFYNDLTDILLKFQCKCSDIVFARKTERDELLKDIQQSIAREPSAPSIPQVP 725 Query: 527 ------KADANPIRTSNIKATSGGTEVSS-QPPVQNEVPARP 631 + + I TS+I + T S+ QPP + PA P Sbjct: 726 SYQSAPSSISTNIATSSIPTPAPRTVFSAKQPPPRPPPPAMP 767
>sp|P79020|PALA_EMENI pH-response regulator protein palA/RIM20 Length = 847 Score = 57.8 bits (138), Expect = 5e-08 Identities = 48/216 (22%), Positives = 98/216 (45%), Gaps = 16/216 (7%) Frame = +2 Query: 38 LRALCNEVEKLKASRNTLVQQLTNLETSS--IGSLLNKAISDDPELNQDQFMEEQLNKLL 211 LR+ +EV +L++ R Q + + + +L+ +A + E Q L Sbjct: 560 LRSCISEVNRLESRRKRKAQAVKDKARADDISSALVREAARLEREFPMQAIQASQFEDLF 619 Query: 212 TPLRQE-------VRESLNVQEKLCAQLQ---QKCSLLNPNESSGANRGSVISALLLAFD 361 ++ V + ++ Q+++ AQ++ + + + ++S R + L + Sbjct: 620 ESRLRDYDVDLDMVAQEMHDQDQIVAQVRDANRAFTRAHTGDASTKEREKALQELENGYL 679 Query: 362 KFHELKSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDLQTSIVREKADAN 541 K+ E+ SN+E G KFY DL +I+ +F++ VK F R+ E +L +D+ + + + Sbjct: 680 KYKEIISNIEVGRKFYNDLAKIVGRFRDDVKAFVHKRRMEASQLEQDISSVAAMASLNIS 739 Query: 542 PIR----TSNIKATSGGTEVSSQPPVQNEVPARPLP 637 PIR + + A + +S P + P +P P Sbjct: 740 PIRQPPQQTVVSAPVSVSAAASVPAPTHFNPVKPQP 775
>sp|Q5KU05|PALA_ASPOR pH-response regulator protein palA/RIM20 Length = 828 Score = 57.8 bits (138), Expect = 5e-08 Identities = 57/217 (26%), Positives = 101/217 (46%), Gaps = 17/217 (7%) Frame = +2 Query: 38 LRALCNEVEKLKASRNTLVQQLTN-LETSSIG-SLLNKAISDDPE-----LNQDQF---M 187 LR +EV +L+ R Q L + T I +LL +A + E + QF Sbjct: 560 LRGCLSEVSRLENRRKRRAQALKDKARTDDISKALLKEAARLEREFPMQAIQASQFEDLF 619 Query: 188 EEQLNKLLTPLRQEVRESLNVQEKLCAQLQQK---CSLLNPNESSGANRGSVISALLLAF 358 EEQL+ T L +E + Q+++ AQ+++ + + ++S R + L + Sbjct: 620 EEQLHLYDTDLEMVTQEQ-HEQDQISAQVREANRAFTRAHTGDASTKEREKALQELENGY 678 Query: 359 DKFHELKSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDLQTSIVREKADA 538 K+ E+ SN+E G KFY DL +I+ +F++ K F R+ E ++ D+ + + Sbjct: 679 LKYKEIISNIEVGRKFYNDLAKIVGRFRDDCKAFVHQRRMEASQIEGDITSVAAMASLNL 738 Query: 539 NP--IRTSNIKATSGGTEVSSQPPVQ--NEVPARPLP 637 + +R + + T V PVQ N++P +P P Sbjct: 739 SQPHLRQYSQQPTQPAQPVQPAQPVQPPNQLPPQPQP 775
>sp|Q51NJ3|PALA_MAGGR pH-response regulator protein palA/RIM20 Length = 849 Score = 47.4 bits (111), Expect = 6e-05 Identities = 36/140 (25%), Positives = 68/140 (48%), Gaps = 1/140 (0%) Frame = +2 Query: 89 LVQQLTNLETSSIGSLLNKAISDDP-ELNQDQFMEEQLNKLLTPLRQEVRESLNVQEKLC 265 ++++ LE + G+ L A DD E D E+ L LL E + LN ++ Sbjct: 604 ILRETGRLERAYPGTTLAAAHFDDFFERRLDSLYEDDL-ALLERETAEQEKCLNEVSRVN 662 Query: 266 AQLQQKCSLLNPNESSGANRGSVISALLLAFDKFHELKSNLEEGLKFYGDLTEILLKFQN 445 + + + +++ G R + + L AF K+ E+ SN+E G KFY DL++I+ F++ Sbjct: 663 REFESQRRAAGADKAGGKEREAALQKLDSAFYKYKEIVSNVEVGRKFYNDLSKIVGTFRD 722 Query: 446 KVKDFCFARKTEKDELMKDL 505 + + R+ + L ++ Sbjct: 723 TCRTWVAERRKDARSLEDEI 742
>sp|Q7S532|PALA_NEUCR pH-response regulator protein palA/rim-20 Length = 886 Score = 45.4 bits (106), Expect = 2e-04 Identities = 38/175 (21%), Positives = 81/175 (46%), Gaps = 19/175 (10%) Frame = +2 Query: 38 LRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQ------------DQ 181 LR+ N+V++L++ R V+ L S + + + L + + Sbjct: 602 LRSAYNDVQRLESRRRKRVESLR--ARSRADDIKPDILVEAARLERAYPTTAIATAHFED 659 Query: 182 FMEEQLNKLLTPLRQEVRESLNVQEKLCAQLQQ-----KCSLLNPNESSGANRG--SVIS 340 F E++L++L + V QEK+ ++++ + + + G NR + Sbjct: 660 FFEKRLDRLYESELEAVERDKQEQEKIVQEVKRANKEFEAQKRQVDRAGGGNREREEALQ 719 Query: 341 ALLLAFDKFHELKSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDL 505 L A+ K+ E+ SN+E G KFY DL++I+ +++ V+ + R+ + L +++ Sbjct: 720 KLDAAYYKYKEIVSNVEVGRKFYNDLSQIVEQWRGLVRGWVSERRRDARSLEEEI 774
>sp|Q9H3S7|PTN23_HUMAN Tyrosine-protein phosphatase, non-receptor type 23 (His-domain containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14) Length = 1636 Score = 43.5 bits (101), Expect = 0.001 Identities = 52/222 (23%), Positives = 93/222 (41%), Gaps = 19/222 (8%) Frame = +2 Query: 23 SVKEVLRALCNEVEKLKASRNTLVQQLTNL-ETSSIGSLLNKAISDDPELNQDQFMEEQL 199 +V + L+ + +V++++ R +L QQL L + I + L +D E+ + EEQL Sbjct: 551 AVLQNLKRILAKVQEMRDQRVSLEQQLRELIQKDDITASL--VTTDHSEMKK--LFEEQL 606 Query: 200 NKLLTPLRQEVRESLNV--QEKLCAQLQQKCSLLNPNESSGANR----------GSVISA 343 K + L V ++ L AQ + C+L N A R S + Sbjct: 607 KKY---------DQLKVYLEQNLAAQDRVLCALTEANVQYAAVRRVLSDLDQKWNSTLQT 657 Query: 344 LLLAFDKFHELKSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELM-KDLQTSIV 520 L+ +++ + +L +EG FY DL + + + C AR+ + +L+ ++L+ Sbjct: 658 LVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAREAARQQLLDRELKKKPP 717 Query: 521 REKADANPI--RTSNIKATSGG---TEVSSQPPVQNEVPARP 631 P+ R +A G E+ S PP P P Sbjct: 718 PRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLP 759
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 95,295,736 Number of Sequences: 369166 Number of extensions: 1834803 Number of successful extensions: 6304 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5937 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6294 length of database: 68,354,980 effective HSP length: 111 effective length of database: 47,849,395 effective search space used: 10335469320 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)