Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_I11
(525 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9QZA2|PDC6I_RAT Programmed cell death 6-interacting pro... 113 3e-25
sp|Q9WU78|PDC6I_MOUSE Programmed cell death 6-interacting p... 112 5e-25
sp|P34552|PQN58_CAEEL Protein pqn-58 (Protein YNK1) 111 9e-25
sp|Q8WUM4|PDC6I_HUMAN Programmed cell death 6-interacting p... 110 3e-24
sp|Q9W6C5|PDC6I_XENLA Programmed cell death 6-interacting p... 106 3e-23
sp|P79020|PALA_EMENI pH-response regulator protein palA/RIM20 51 2e-06
sp|Q5KU05|PALA_ASPOR pH-response regulator protein palA/RIM20 51 2e-06
sp|Q51NJ3|PALA_MAGGR pH-response regulator protein palA/RIM20 47 4e-05
sp|Q7S532|PALA_NEUCR pH-response regulator protein palA/rim-20 45 1e-04
sp|Q9H3S7|PTN23_HUMAN Tyrosine-protein phosphatase, non-rec... 43 4e-04
>sp|Q9QZA2|PDC6I_RAT Programmed cell death 6-interacting protein (ALG-2 interacting
protein 1)
Length = 401
Score = 113 bits (282), Expect = 3e-25
Identities = 65/169 (38%), Positives = 100/169 (59%), Gaps = 3/169 (1%)
Frame = +2
Query: 26 VKEVLRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQDQFMEEQLNK 205
V VL++L + ++++K R L L ++ L A++ D +N++ +L++
Sbjct: 81 VVNVLKSLLSNLDEIKKEREGLENDLKSVNFDMTSKFLT-ALAQDGVINEEALSVTELDR 139
Query: 206 LLTPLRQEVRESLNVQEKLCAQLQ---QKCSLLNPNESSGANRGSVISALLLAFDKFHEL 376
+ L +V+ESL QE L +Q Q+ S + + S + R V+ L A+D F EL
Sbjct: 140 IYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNSEASLREEVLKNLATAYDNFVEL 199
Query: 377 KSNLEEGLKFYGDLTDILLKFQNKVKDFCFARKTEKDELMKDLQTSIVR 523
+NL+EG KFY +LT+IL++FQNK D FARKTE+DEL+KDLQ SI R
Sbjct: 200 VANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAR 248
>sp|Q9WU78|PDC6I_MOUSE Programmed cell death 6-interacting protein (ALG-2 interacting
protein X) (ALG-2 interacting protein 1) (E2F1-inducible
protein) (Eig2)
Length = 869
Score = 112 bits (280), Expect = 5e-25
Identities = 64/169 (37%), Positives = 100/169 (59%), Gaps = 3/169 (1%)
Frame = +2
Query: 26 VKEVLRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQDQFMEEQLNK 205
V VL++L + ++++K R +L L ++ L A++ D +N++ +L++
Sbjct: 548 VVSVLKSLLSNLDEIKKERESLENDLKSVNFDMTSKFLT-ALAQDGVINEEALSVTELDR 606
Query: 206 LLTPLRQEVRESLNVQEKLCAQLQ---QKCSLLNPNESSGANRGSVISALLLAFDKFHEL 376
+ L +V+ESL QE L +Q Q+ S + + + R V+ L A+D F EL
Sbjct: 607 IYGGLTSKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVEL 666
Query: 377 KSNLEEGLKFYGDLTDILLKFQNKVKDFCFARKTEKDELMKDLQTSIVR 523
+NL+EG KFY +LT+IL++FQNK D FARKTE+DEL+KDLQ SI R
Sbjct: 667 VANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAR 715
>sp|P34552|PQN58_CAEEL Protein pqn-58 (Protein YNK1)
Length = 861
Score = 111 bits (278), Expect = 9e-25
Identities = 64/173 (36%), Positives = 104/173 (60%), Gaps = 3/173 (1%)
Frame = +2
Query: 11 GNSDSVKEVLRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQDQFME 190
G +D+V++ LR ++ ++ R L ++L N L KA++++ +N++ +
Sbjct: 550 GETDTVRQ-LRQFMSQWNEVTTDRELLEKELKNTNCDIANDFL-KAMAENQLINEEHISK 607
Query: 191 EQLNKLLTPLRQEVRESLNVQEKLCAQLQQKCSLLNPNE---SSGANRGSVISALLLAFD 361
E++ ++ L++ V+ SL+ QE L Q+Q + + S+GA R ++ L A D
Sbjct: 608 EKIAQIFGDLKRRVQSSLDTQETLMNQIQAANNTFTGEKTGSSTGAERERILKMLAQASD 667
Query: 362 KFHELKSNLEEGLKFYGDLTDILLKFQNKVKDFCFARKTEKDELMKDLQTSIV 520
+ ELK+NLEEG KFY DLT IL++ Q KV DF FAR+TEK++LM+ LQ SIV
Sbjct: 668 AYVELKANLEEGTKFYNDLTPILVRLQQKVSDFAFARQTEKEDLMRQLQLSIV 720
>sp|Q8WUM4|PDC6I_HUMAN Programmed cell death 6-interacting protein (PDCD6-interacting
protein) (ALG-2 interacting protein 1) (Hp95)
Length = 868
Score = 110 bits (274), Expect = 3e-24
Identities = 64/169 (37%), Positives = 99/169 (58%), Gaps = 3/169 (1%)
Frame = +2
Query: 26 VKEVLRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQDQFMEEQLNK 205
V VL++L + ++++K R L L ++ L A++ D +N++ +L++
Sbjct: 548 VVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLT-ALAQDGVINEEALSVTELDR 606
Query: 206 LLTPLRQEVRESLNVQEKLCAQLQ---QKCSLLNPNESSGANRGSVISALLLAFDKFHEL 376
+ L +V+ESL QE L +Q Q+ S + + + R V+ L A+D F EL
Sbjct: 607 VYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVEL 666
Query: 377 KSNLEEGLKFYGDLTDILLKFQNKVKDFCFARKTEKDELMKDLQTSIVR 523
+NL+EG KFY +LT+IL++FQNK D FARKTE+DEL+KDLQ SI R
Sbjct: 667 VANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAR 715
>sp|Q9W6C5|PDC6I_XENLA Programmed cell death 6-interacting protein (Signal transduction
protein Xp95)
Length = 867
Score = 106 bits (265), Expect = 3e-23
Identities = 63/169 (37%), Positives = 96/169 (56%), Gaps = 3/169 (1%)
Frame = +2
Query: 26 VKEVLRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQDQFMEEQLNK 205
V VL++L N+++ +K R L + ++ L A++ D +N++ +L++
Sbjct: 547 VVTVLKSLLNKLDDMKKEREQLENDIKSVNFDMTTKFLT-ALAQDGAVNEEAISVTELDQ 605
Query: 206 LLTPLRQEVRESLNVQEKLCAQLQ---QKCSLLNPNESSGANRGSVISALLLAFDKFHEL 376
+ +V+E+L QE L +Q Q+ S + + S R V+ L + D + EL
Sbjct: 606 IYGSYTYKVQENLKKQEDLLNNIQSAHQEFSKMKQSNSEANLREEVLKNLAVGHDNYIEL 665
Query: 377 KSNLEEGLKFYGDLTDILLKFQNKVKDFCFARKTEKDELMKDLQTSIVR 523
+NL+EG KFY DLTDILLKFQ K D FARKTE+DEL+KD+Q SI R
Sbjct: 666 VANLKEGTKFYNDLTDILLKFQCKCSDIVFARKTERDELLKDIQQSIAR 714
>sp|P79020|PALA_EMENI pH-response regulator protein palA/RIM20
Length = 847
Score = 50.8 bits (120), Expect = 2e-06
Identities = 39/170 (22%), Positives = 80/170 (47%), Gaps = 12/170 (7%)
Frame = +2
Query: 38 LRALCNEVEKLKASRNTLVQQLTNLETSS--IGSLLNKAISDDPELNQDQFMEEQLNKLL 211
LR+ +EV +L++ R Q + + + +L+ +A + E Q L
Sbjct: 560 LRSCISEVNRLESRRKRKAQAVKDKARADDISSALVREAARLEREFPMQAIQASQFEDLF 619
Query: 212 TPLRQE-------VRESLNVQEKLCAQLQ---QKCSLLNPNESSGANRGSVISALLLAFD 361
++ V + ++ Q+++ AQ++ + + + ++S R + L +
Sbjct: 620 ESRLRDYDVDLDMVAQEMHDQDQIVAQVRDANRAFTRAHTGDASTKEREKALQELENGYL 679
Query: 362 KFHELKSNLEEGLKFYGDLTDILLKFQNKVKDFCFARKTEKDELMKDLQT 511
K+ E+ SN+E G KFY DL I+ +F++ VK F R+ E +L +D+ +
Sbjct: 680 KYKEIISNIEVGRKFYNDLAKIVGRFRDDVKAFVHKRRMEASQLEQDISS 729
>sp|Q5KU05|PALA_ASPOR pH-response regulator protein palA/RIM20
Length = 828
Score = 50.8 bits (120), Expect = 2e-06
Identities = 47/169 (27%), Positives = 81/169 (47%), Gaps = 13/169 (7%)
Frame = +2
Query: 38 LRALCNEVEKLKASRNTLVQQLTN-LETSSIG-SLLNKAISDDPE-----LNQDQF---M 187
LR +EV +L+ R Q L + T I +LL +A + E + QF
Sbjct: 560 LRGCLSEVSRLENRRKRRAQALKDKARTDDISKALLKEAARLEREFPMQAIQASQFEDLF 619
Query: 188 EEQLNKLLTPLRQEVRESLNVQEKLCAQLQQK---CSLLNPNESSGANRGSVISALLLAF 358
EEQL+ T L +E + Q+++ AQ+++ + + ++S R + L +
Sbjct: 620 EEQLHLYDTDLEMVTQEQ-HEQDQISAQVREANRAFTRAHTGDASTKEREKALQELENGY 678
Query: 359 DKFHELKSNLEEGLKFYGDLTDILLKFQNKVKDFCFARKTEKDELMKDL 505
K+ E+ SN+E G KFY DL I+ +F++ K F R+ E ++ D+
Sbjct: 679 LKYKEIISNIEVGRKFYNDLAKIVGRFRDDCKAFVHQRRMEASQIEGDI 727
>sp|Q51NJ3|PALA_MAGGR pH-response regulator protein palA/RIM20
Length = 849
Score = 46.6 bits (109), Expect = 4e-05
Identities = 36/140 (25%), Positives = 67/140 (47%), Gaps = 1/140 (0%)
Frame = +2
Query: 89 LVQQLTNLETSSIGSLLNKAISDDP-ELNQDQFMEEQLNKLLTPLRQEVRESLNVQEKLC 265
++++ LE + G+ L A DD E D E+ L LL E + LN ++
Sbjct: 604 ILRETGRLERAYPGTTLAAAHFDDFFERRLDSLYEDDL-ALLERETAEQEKCLNEVSRVN 662
Query: 266 AQLQQKCSLLNPNESSGANRGSVISALLLAFDKFHELKSNLEEGLKFYGDLTDILLKFQN 445
+ + + +++ G R + + L AF K+ E+ SN+E G KFY DL+ I+ F++
Sbjct: 663 REFESQRRAAGADKAGGKEREAALQKLDSAFYKYKEIVSNVEVGRKFYNDLSKIVGTFRD 722
Query: 446 KVKDFCFARKTEKDELMKDL 505
+ + R+ + L ++
Sbjct: 723 TCRTWVAERRKDARSLEDEI 742
>sp|Q7S532|PALA_NEUCR pH-response regulator protein palA/rim-20
Length = 886
Score = 44.7 bits (104), Expect = 1e-04
Identities = 38/175 (21%), Positives = 80/175 (45%), Gaps = 19/175 (10%)
Frame = +2
Query: 38 LRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQ------------DQ 181
LR+ N+V++L++ R V+ L S + + + L + +
Sbjct: 602 LRSAYNDVQRLESRRRKRVESLR--ARSRADDIKPDILVEAARLERAYPTTAIATAHFED 659
Query: 182 FMEEQLNKLLTPLRQEVRESLNVQEKLCAQLQQ-----KCSLLNPNESSGANRG--SVIS 340
F E++L++L + V QEK+ ++++ + + + G NR +
Sbjct: 660 FFEKRLDRLYESELEAVERDKQEQEKIVQEVKRANKEFEAQKRQVDRAGGGNREREEALQ 719
Query: 341 ALLLAFDKFHELKSNLEEGLKFYGDLTDILLKFQNKVKDFCFARKTEKDELMKDL 505
L A+ K+ E+ SN+E G KFY DL+ I+ +++ V+ + R+ + L +++
Sbjct: 720 KLDAAYYKYKEIVSNVEVGRKFYNDLSQIVEQWRGLVRGWVSERRRDARSLEEEI 774
>sp|Q9H3S7|PTN23_HUMAN Tyrosine-protein phosphatase, non-receptor type 23 (His-domain
containing protein tyrosine phosphatase) (HD-PTP)
(Protein tyrosine phosphatase TD14) (PTP-TD14)
Length = 1636
Score = 43.1 bits (100), Expect = 4e-04
Identities = 41/171 (23%), Positives = 76/171 (44%), Gaps = 13/171 (7%)
Frame = +2
Query: 23 SVKEVLRALCNEVEKLKASRNTLVQQLTNL-ETSSIGSLLNKAISDDPELNQDQFMEEQL 199
+V + L+ + +V++++ R +L QQL L + I + L +D E+ + EEQL
Sbjct: 551 AVLQNLKRILAKVQEMRDQRVSLEQQLRELIQKDDITASL--VTTDHSEMKK--LFEEQL 606
Query: 200 NKLLTPLRQEVRESLNV--QEKLCAQLQQKCSLLNPNESSGANR----------GSVISA 343
K + L V ++ L AQ + C+L N A R S +
Sbjct: 607 KKY---------DQLKVYLEQNLAAQDRVLCALTEANVQYAAVRRVLSDLDQKWNSTLQT 657
Query: 344 LLLAFDKFHELKSNLEEGLKFYGDLTDILLKFQNKVKDFCFARKTEKDELM 496
L+ +++ + +L +EG FY DL + + + C AR+ + +L+
Sbjct: 658 LVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAREAARQQLL 708
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,239,288
Number of Sequences: 369166
Number of extensions: 1026870
Number of successful extensions: 3327
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3209
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3325
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3502236525
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)