Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_K12
(894 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9QZA2|PDC6I_RAT Programmed cell death 6-interacting pro... 124 5e-28
sp|Q8WUM4|PDC6I_HUMAN Programmed cell death 6-interacting p... 120 5e-27
sp|Q9WU78|PDC6I_MOUSE Programmed cell death 6-interacting p... 120 5e-27
sp|P34552|PQN58_CAEEL Protein pqn-58 (Protein YNK1) 111 2e-24
sp|Q9W6C5|PDC6I_XENLA Programmed cell death 6-interacting p... 109 9e-24
sp|P79020|PALA_EMENI pH-response regulator protein palA/RIM20 58 4e-08
sp|Q5KU05|PALA_ASPOR pH-response regulator protein palA/RIM20 58 4e-08
sp|Q51NJ3|PALA_MAGGR pH-response regulator protein palA/RIM20 47 6e-05
sp|Q7S532|PALA_NEUCR pH-response regulator protein palA/rim-20 45 2e-04
sp|Q9H3S7|PTN23_HUMAN Tyrosine-protein phosphatase, non-rec... 44 8e-04
>sp|Q9QZA2|PDC6I_RAT Programmed cell death 6-interacting protein (ALG-2 interacting
protein 1)
Length = 401
Score = 124 bits (310), Expect = 5e-28
Identities = 74/207 (35%), Positives = 116/207 (56%), Gaps = 3/207 (1%)
Frame = +1
Query: 19 VKEVLRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQDQFMEEQLNK 198
V VL++L + ++++K R L L ++ L A++ D +N++ +L++
Sbjct: 81 VVNVLKSLLSNLDEIKKEREGLENDLKSVNFDMTSKFLT-ALAQDGVINEEALSVTELDR 139
Query: 199 LLTPLRQEVRESLNVQEKLCAQLQ---QKCSLLNPNESSGANRGSVISALLLAFDKFHEL 369
+ L +V+ESL QE L +Q Q+ S + + S + R V+ L A+D F EL
Sbjct: 140 IYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNSEASLREEVLKNLATAYDNFVEL 199
Query: 370 KSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDLQTSIVREKADANPIRTS 549
+NL+EG KFY +LTEIL++FQNK D FARKTE+DEL+KDLQ SI RE + + +
Sbjct: 200 VANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPPPA 259
Query: 550 NIKATSGGTEVSSQPPVQNEVPARPLP 630
+ +GG + P + PA+P P
Sbjct: 260 YQSSPAGGHATAPTPAPRTMPPAKPQP 286
>sp|Q8WUM4|PDC6I_HUMAN Programmed cell death 6-interacting protein (PDCD6-interacting
protein) (ALG-2 interacting protein 1) (Hp95)
Length = 868
Score = 120 bits (301), Expect = 5e-27
Identities = 77/215 (35%), Positives = 118/215 (54%), Gaps = 11/215 (5%)
Frame = +1
Query: 19 VKEVLRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQDQFMEEQLNK 198
V VL++L + ++++K R L L ++ L A++ D +N++ +L++
Sbjct: 548 VVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLT-ALAQDGVINEEALSVTELDR 606
Query: 199 LLTPLRQEVRESLNVQEKLCAQLQ---QKCSLLNPNESSGANRGSVISALLLAFDKFHEL 369
+ L +V+ESL QE L +Q Q+ S + + + R V+ L A+D F EL
Sbjct: 607 VYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVEL 666
Query: 370 KSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDLQTSIVREKADANPIRTS 549
+NL+EG KFY +LTEIL++FQNK D FARKTE+DEL+KDLQ SI RE + A I T
Sbjct: 667 VANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPS-APSIPTP 725
Query: 550 NIKATSGGTEV--------SSQPPVQNEVPARPLP 630
+++ G + PP + + PARP P
Sbjct: 726 AYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPP 760
>sp|Q9WU78|PDC6I_MOUSE Programmed cell death 6-interacting protein (ALG-2 interacting
protein X) (ALG-2 interacting protein 1) (E2F1-inducible
protein) (Eig2)
Length = 869
Score = 120 bits (301), Expect = 5e-27
Identities = 74/208 (35%), Positives = 113/208 (54%), Gaps = 4/208 (1%)
Frame = +1
Query: 19 VKEVLRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQDQFMEEQLNK 198
V VL++L + ++++K R +L L ++ L A++ D +N++ +L++
Sbjct: 548 VVSVLKSLLSNLDEIKKERESLENDLKSVNFDMTSKFLT-ALAQDGVINEEALSVTELDR 606
Query: 199 LLTPLRQEVRESLNVQEKLCAQLQ---QKCSLLNPNESSGANRGSVISALLLAFDKFHEL 369
+ L +V+ESL QE L +Q Q+ S + + + R V+ L A+D F EL
Sbjct: 607 IYGGLTSKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVEL 666
Query: 370 KSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDLQTSIVRE-KADANPIRT 546
+NL+EG KFY +LTEIL++FQNK D FARKTE+DEL+KDLQ SI RE A + P
Sbjct: 667 VANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPPPA 726
Query: 547 SNIKATSGGTEVSSQPPVQNEVPARPLP 630
+G P + PA+P P
Sbjct: 727 YQSSPAAGHAAAPPTPAPRTMPPAKPQP 754
>sp|P34552|PQN58_CAEEL Protein pqn-58 (Protein YNK1)
Length = 861
Score = 111 bits (278), Expect = 2e-24
Identities = 64/173 (36%), Positives = 104/173 (60%), Gaps = 3/173 (1%)
Frame = +1
Query: 4 GNSDSVKEVLRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQDQFME 183
G +D+V++ LR ++ ++ R L ++L N L KA++++ +N++ +
Sbjct: 550 GETDTVRQ-LRQFMSQWNEVTTDRELLEKELKNTNCDIANDFL-KAMAENQLINEEHISK 607
Query: 184 EQLNKLLTPLRQEVRESLNVQEKLCAQLQQKCSLLNPNE---SSGANRGSVISALLLAFD 354
E++ ++ L++ V+ SL+ QE L Q+Q + + S+GA R ++ L A D
Sbjct: 608 EKIAQIFGDLKRRVQSSLDTQETLMNQIQAANNTFTGEKTGSSTGAERERILKMLAQASD 667
Query: 355 KFHELKSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDLQTSIV 513
+ ELK+NLEEG KFY DLT IL++ Q KV DF FAR+TEK++LM+ LQ SIV
Sbjct: 668 AYVELKANLEEGTKFYNDLTPILVRLQQKVSDFAFARQTEKEDLMRQLQLSIV 720
>sp|Q9W6C5|PDC6I_XENLA Programmed cell death 6-interacting protein (Signal transduction
protein Xp95)
Length = 867
Score = 109 bits (273), Expect = 9e-24
Identities = 75/222 (33%), Positives = 115/222 (51%), Gaps = 20/222 (9%)
Frame = +1
Query: 19 VKEVLRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQDQFMEEQLNK 198
V VL++L N+++ +K R L + ++ L A++ D +N++ +L++
Sbjct: 547 VVTVLKSLLNKLDDMKKEREQLENDIKSVNFDMTTKFLT-ALAQDGAVNEEAISVTELDQ 605
Query: 199 LLTPLRQEVRESLNVQEKLCAQLQ---QKCSLLNPNESSGANRGSVISALLLAFDKFHEL 369
+ +V+E+L QE L +Q Q+ S + + S R V+ L + D + EL
Sbjct: 606 IYGSYTYKVQENLKKQEDLLNNIQSAHQEFSKMKQSNSEANLREEVLKNLAVGHDNYIEL 665
Query: 370 KSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDLQTSIVRE---------- 519
+NL+EG KFY DLT+ILLKFQ K D FARKTE+DEL+KD+Q SI RE
Sbjct: 666 VANLKEGTKFYNDLTDILLKFQCKCSDIVFARKTERDELLKDIQQSIAREPSAPSIPQVP 725
Query: 520 ------KADANPIRTSNIKATSGGTEVSS-QPPVQNEVPARP 624
+ + I TS+I + T S+ QPP + PA P
Sbjct: 726 SYQSAPSSISTNIATSSIPTPAPRTVFSAKQPPPRPPPPAMP 767
>sp|P79020|PALA_EMENI pH-response regulator protein palA/RIM20
Length = 847
Score = 57.8 bits (138), Expect = 4e-08
Identities = 48/216 (22%), Positives = 98/216 (45%), Gaps = 16/216 (7%)
Frame = +1
Query: 31 LRALCNEVEKLKASRNTLVQQLTNLETSS--IGSLLNKAISDDPELNQDQFMEEQLNKLL 204
LR+ +EV +L++ R Q + + + +L+ +A + E Q L
Sbjct: 560 LRSCISEVNRLESRRKRKAQAVKDKARADDISSALVREAARLEREFPMQAIQASQFEDLF 619
Query: 205 TPLRQE-------VRESLNVQEKLCAQLQ---QKCSLLNPNESSGANRGSVISALLLAFD 354
++ V + ++ Q+++ AQ++ + + + ++S R + L +
Sbjct: 620 ESRLRDYDVDLDMVAQEMHDQDQIVAQVRDANRAFTRAHTGDASTKEREKALQELENGYL 679
Query: 355 KFHELKSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDLQTSIVREKADAN 534
K+ E+ SN+E G KFY DL +I+ +F++ VK F R+ E +L +D+ + + +
Sbjct: 680 KYKEIISNIEVGRKFYNDLAKIVGRFRDDVKAFVHKRRMEASQLEQDISSVAAMASLNIS 739
Query: 535 PIR----TSNIKATSGGTEVSSQPPVQNEVPARPLP 630
PIR + + A + +S P + P +P P
Sbjct: 740 PIRQPPQQTVVSAPVSVSAAASVPAPTHFNPVKPQP 775
>sp|Q5KU05|PALA_ASPOR pH-response regulator protein palA/RIM20
Length = 828
Score = 57.8 bits (138), Expect = 4e-08
Identities = 57/217 (26%), Positives = 101/217 (46%), Gaps = 17/217 (7%)
Frame = +1
Query: 31 LRALCNEVEKLKASRNTLVQQLTN-LETSSIG-SLLNKAISDDPE-----LNQDQF---M 180
LR +EV +L+ R Q L + T I +LL +A + E + QF
Sbjct: 560 LRGCLSEVSRLENRRKRRAQALKDKARTDDISKALLKEAARLEREFPMQAIQASQFEDLF 619
Query: 181 EEQLNKLLTPLRQEVRESLNVQEKLCAQLQQK---CSLLNPNESSGANRGSVISALLLAF 351
EEQL+ T L +E + Q+++ AQ+++ + + ++S R + L +
Sbjct: 620 EEQLHLYDTDLEMVTQEQ-HEQDQISAQVREANRAFTRAHTGDASTKEREKALQELENGY 678
Query: 352 DKFHELKSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDLQTSIVREKADA 531
K+ E+ SN+E G KFY DL +I+ +F++ K F R+ E ++ D+ + +
Sbjct: 679 LKYKEIISNIEVGRKFYNDLAKIVGRFRDDCKAFVHQRRMEASQIEGDITSVAAMASLNL 738
Query: 532 NP--IRTSNIKATSGGTEVSSQPPVQ--NEVPARPLP 630
+ +R + + T V PVQ N++P +P P
Sbjct: 739 SQPHLRQYSQQPTQPAQPVQPAQPVQPPNQLPPQPQP 775
>sp|Q51NJ3|PALA_MAGGR pH-response regulator protein palA/RIM20
Length = 849
Score = 47.4 bits (111), Expect = 6e-05
Identities = 36/140 (25%), Positives = 68/140 (48%), Gaps = 1/140 (0%)
Frame = +1
Query: 82 LVQQLTNLETSSIGSLLNKAISDDP-ELNQDQFMEEQLNKLLTPLRQEVRESLNVQEKLC 258
++++ LE + G+ L A DD E D E+ L LL E + LN ++
Sbjct: 604 ILRETGRLERAYPGTTLAAAHFDDFFERRLDSLYEDDL-ALLERETAEQEKCLNEVSRVN 662
Query: 259 AQLQQKCSLLNPNESSGANRGSVISALLLAFDKFHELKSNLEEGLKFYGDLTEILLKFQN 438
+ + + +++ G R + + L AF K+ E+ SN+E G KFY DL++I+ F++
Sbjct: 663 REFESQRRAAGADKAGGKEREAALQKLDSAFYKYKEIVSNVEVGRKFYNDLSKIVGTFRD 722
Query: 439 KVKDFCFARKTEKDELMKDL 498
+ + R+ + L ++
Sbjct: 723 TCRTWVAERRKDARSLEDEI 742
>sp|Q7S532|PALA_NEUCR pH-response regulator protein palA/rim-20
Length = 886
Score = 45.4 bits (106), Expect = 2e-04
Identities = 38/175 (21%), Positives = 81/175 (46%), Gaps = 19/175 (10%)
Frame = +1
Query: 31 LRALCNEVEKLKASRNTLVQQLTNLETSSIGSLLNKAISDDPELNQ------------DQ 174
LR+ N+V++L++ R V+ L S + + + L + +
Sbjct: 602 LRSAYNDVQRLESRRRKRVESLR--ARSRADDIKPDILVEAARLERAYPTTAIATAHFED 659
Query: 175 FMEEQLNKLLTPLRQEVRESLNVQEKLCAQLQQ-----KCSLLNPNESSGANRG--SVIS 333
F E++L++L + V QEK+ ++++ + + + G NR +
Sbjct: 660 FFEKRLDRLYESELEAVERDKQEQEKIVQEVKRANKEFEAQKRQVDRAGGGNREREEALQ 719
Query: 334 ALLLAFDKFHELKSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELMKDL 498
L A+ K+ E+ SN+E G KFY DL++I+ +++ V+ + R+ + L +++
Sbjct: 720 KLDAAYYKYKEIVSNVEVGRKFYNDLSQIVEQWRGLVRGWVSERRRDARSLEEEI 774
>sp|Q9H3S7|PTN23_HUMAN Tyrosine-protein phosphatase, non-receptor type 23 (His-domain
containing protein tyrosine phosphatase) (HD-PTP)
(Protein tyrosine phosphatase TD14) (PTP-TD14)
Length = 1636
Score = 43.5 bits (101), Expect = 8e-04
Identities = 52/222 (23%), Positives = 93/222 (41%), Gaps = 19/222 (8%)
Frame = +1
Query: 16 SVKEVLRALCNEVEKLKASRNTLVQQLTNL-ETSSIGSLLNKAISDDPELNQDQFMEEQL 192
+V + L+ + +V++++ R +L QQL L + I + L +D E+ + EEQL
Sbjct: 551 AVLQNLKRILAKVQEMRDQRVSLEQQLRELIQKDDITASL--VTTDHSEMKK--LFEEQL 606
Query: 193 NKLLTPLRQEVRESLNV--QEKLCAQLQQKCSLLNPNESSGANR----------GSVISA 336
K + L V ++ L AQ + C+L N A R S +
Sbjct: 607 KKY---------DQLKVYLEQNLAAQDRVLCALTEANVQYAAVRRVLSDLDQKWNSTLQT 657
Query: 337 LLLAFDKFHELKSNLEEGLKFYGDLTEILLKFQNKVKDFCFARKTEKDELM-KDLQTSIV 513
L+ +++ + +L +EG FY DL + + + C AR+ + +L+ ++L+
Sbjct: 658 LVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAREAARQQLLDRELKKKPP 717
Query: 514 REKADANPI--RTSNIKATSGG---TEVSSQPPVQNEVPARP 624
P+ R +A G E+ S PP P P
Sbjct: 718 PRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLP 759
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.310 0.128 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,998,827
Number of Sequences: 369166
Number of extensions: 1764764
Number of successful extensions: 4688
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4451
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4684
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8982382310
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)