Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00886 (995 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9JKK7|TMOD2_MOUSE Tropomodulin-2 (Neuronal tropomodulin... 134 4e-31 sp|P70566|TMOD2_RAT Tropomodulin-2 (Neuronal tropomodulin) ... 134 5e-31 sp|P49813|TMOD1_MOUSE Tropomodulin-1 (Erythrocyte tropomodu... 132 2e-30 sp|P70567|TMOD1_RAT Tropomodulin-1 (Erythrocyte tropomoduli... 130 8e-30 sp|Q9NZR1|TMOD2_HUMAN Tropomodulin-2 (Neuronal tropomodulin... 129 1e-29 sp|P28289|TMOD1_HUMAN Tropomodulin-1 (Erythrocyte tropomodu... 129 1e-29 sp|Q9JHJ0|TMOD3_MOUSE Tropomodulin-3 (Ubiquitous tropomodul... 122 2e-27 sp|Q9NYL9|TMOD3_HUMAN Tropomodulin-3 (Ubiquitous tropomodul... 121 4e-27 sp|Q9JLH8|TMOD4_MOUSE Tropomodulin-4 (Skeletal muscle tropo... 118 3e-26 sp|Q9NZQ9|TMOD4_HUMAN Tropomodulin-4 (Skeletal muscle tropo... 115 3e-25
>sp|Q9JKK7|TMOD2_MOUSE Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod) Length = 351 Score = 134 bits (337), Expect = 4e-31 Identities = 79/226 (34%), Positives = 126/226 (55%) Frame = +3 Query: 45 DTEFDEALKNATEEELVDLAAVLGFNGMLNQTQYHASVENKEQMCGGFQGVAKYESCKPV 224 D E +EAL +A++ EL DLAAVLG + +LN ++ N + G + V K E KPV Sbjct: 116 DPELEEALASASDTELYDLAAVLGVHNLLNNPKFDEETTNGQGRKGPVRNVVKGEKAKPV 175 Query: 225 PDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNINEDVIKRLCEXXXXXXXXXXXXXXX 404 +EP N T+VE+ +++++AND SL+EVNLNN+KNI +K + Sbjct: 176 FEEPPNPTNVEASLQQMKANDPSLQEVNLNNIKNIPIPTLKEFAKSLETNTHVKKFSLAA 235 Query: 405 IGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGLLELRVVNQQQ 584 ++ F +L+ N L++LN+ESN++ G I+ L+ A+ RE L E+++ NQ+Q Sbjct: 236 TRSNDPVALAFAEMLKVNKTLKSLNVESNFITGTGILALVEAL-RENDTLTEIKIDNQRQ 294 Query: 585 KVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVD 722 + LG VE EI ++++EN+ + G R R+ + N D Sbjct: 295 Q-LGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNND 339
>sp|P70566|TMOD2_RAT Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod) Length = 351 Score = 134 bits (336), Expect = 5e-31 Identities = 79/226 (34%), Positives = 126/226 (55%) Frame = +3 Query: 45 DTEFDEALKNATEEELVDLAAVLGFNGMLNQTQYHASVENKEQMCGGFQGVAKYESCKPV 224 D E +EAL +A++ EL DLAAVLG + +LN ++ N + G + V K E KPV Sbjct: 116 DPELEEALASASDTELYDLAAVLGVHNLLNNPKFDEETTNGQGRKGPVRNVVKGEKAKPV 175 Query: 225 PDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNINEDVIKRLCEXXXXXXXXXXXXXXX 404 +EP N T+VE+ +++++AND SL+EVNLNN+KNI +K + Sbjct: 176 FEEPPNPTNVEASLQQMKANDPSLQEVNLNNIKNIPIPTLKEFAKALETNTHVRKFSLAA 235 Query: 405 IGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGLLELRVVNQQQ 584 ++ F +L+ N L++LN+ESN++ G I+ L+ A+ RE L E+++ NQ+Q Sbjct: 236 TRSNDPVALAFAEMLKVNKTLKSLNVESNFITGAGILALVEAL-RENDTLTEIKIDNQRQ 294 Query: 585 KVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVD 722 + LG VE EI ++++EN+ + G R R+ + N D Sbjct: 295 Q-LGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNND 339
>sp|P49813|TMOD1_MOUSE Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod) Length = 359 Score = 132 bits (331), Expect = 2e-30 Identities = 84/241 (34%), Positives = 132/241 (54%), Gaps = 5/241 (2%) Frame = +3 Query: 45 DTEFDEALKNATEEELVDLAAVLGFNGMLNQTQYH-----ASVENKEQMCGGFQGVAKYE 209 + E +EAL NA++ EL D+AA+LG + +++ QY+ +S+ NKE G V K Sbjct: 113 EPELEEALANASDAELCDIAAILGMHTLMSNQQYYQALGSSSIVNKE----GLNSVIKPT 168 Query: 210 SCKPVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNINEDVIKRLCEXXXXXXXXXX 389 KPVPDE N TDVE +++++ ND L+EVNLNN++NI +K E Sbjct: 169 QYKPVPDEEPNSTDVEETLERIKNNDPELEEVNLNNIRNIPIPTLKAYAEALKENSYVKK 228 Query: 390 XXXXXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGLLELRV 569 ++ +L+ N L+TLN+ESN+++G I++L+ A+ S L+EL++ Sbjct: 229 FSIVGTRSNDPVAFALAEMLKVNKVLKTLNVESNFISGAGILRLVEALPHNTS-LVELKI 287 Query: 570 VNQQQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVDKKTRQNRLV 749 NQ Q LG +VE EI ++++NTTL G R+R + + N D R+ RL Sbjct: 288 DNQSQP-LGNKVEMEIVNMLEKNTTLLKFGYHFTQQGPRLRASNAMMSNND-LVRKRRLA 345 Query: 750 N 752 + Sbjct: 346 D 346
>sp|P70567|TMOD1_RAT Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod) Length = 359 Score = 130 bits (326), Expect = 8e-30 Identities = 84/241 (34%), Positives = 132/241 (54%), Gaps = 5/241 (2%) Frame = +3 Query: 45 DTEFDEALKNATEEELVDLAAVLGFNGMLNQTQYH-----ASVENKEQMCGGFQGVAKYE 209 + E +EAL NA++ EL D+AA+LG + +++ QY+ +S+ NKE G V K Sbjct: 113 EPELEEALANASDAELCDIAAILGMHTLMSNQQYYQALGSSSIVNKE----GLNSVIKPT 168 Query: 210 SCKPVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNINEDVIKRLCEXXXXXXXXXX 389 KPVPDE N TDVE +++++ ND L+EVNLNN++NI +K E Sbjct: 169 QYKPVPDEEPNPTDVEETLERIKNNDPELEEVNLNNIRNIPIPTLKAYAESLKENSYVKK 228 Query: 390 XXXXXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGLLELRV 569 ++ +L+ N L+TLN+ESN+++G I+ L+ A+ S L+EL++ Sbjct: 229 FSIVGTRSNDPVAFALAEMLKVNKVLKTLNVESNFISGAGILCLVEALPHNTS-LVELKI 287 Query: 570 VNQQQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVDKKTRQNRLV 749 NQ Q LG +VE EI ++++NTTL G R+R + + MN + R+ RL Sbjct: 288 DNQSQP-LGNKVEMEIVNMLEKNTTLLKFGYHFTQQGPRLRASNAM-MNNNDLVRKRRLA 345 Query: 750 N 752 + Sbjct: 346 D 346
>sp|Q9NZR1|TMOD2_HUMAN Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod) Length = 351 Score = 129 bits (325), Expect = 1e-29 Identities = 77/226 (34%), Positives = 124/226 (54%) Frame = +3 Query: 45 DTEFDEALKNATEEELVDLAAVLGFNGMLNQTQYHASVENKEQMCGGFQGVAKYESCKPV 224 D E +EAL +A++ EL DLAAVLG + +LN ++ N + G + V K E KPV Sbjct: 116 DPELEEALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPV 175 Query: 225 PDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNINEDVIKRLCEXXXXXXXXXXXXXXX 404 +EP N T+VE +++++AND SL+EVNLNN+KNI ++ + Sbjct: 176 FEEPPNPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAA 235 Query: 405 IGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGLLELRVVNQQQ 584 ++ F +L+ N L +LN+ESN++ G I+ L+ A+ +E L E+++ NQ+Q Sbjct: 236 TRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEAL-KENDTLTEIKIDNQRQ 294 Query: 585 KVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVD 722 + LG VE EI ++++EN+ + G R R+ + N D Sbjct: 295 Q-LGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNND 339
>sp|P28289|TMOD1_HUMAN Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod) Length = 359 Score = 129 bits (325), Expect = 1e-29 Identities = 82/241 (34%), Positives = 133/241 (55%), Gaps = 5/241 (2%) Frame = +3 Query: 45 DTEFDEALKNATEEELVDLAAVLGFNGMLNQTQYH-----ASVENKEQMCGGFQGVAKYE 209 + E +EAL NA++ EL D+AA+LG + +++ QY+ +S+ NKE G V K Sbjct: 113 EPELEEALANASDAELCDIAAILGMHTLMSNQQYYQALSSSSIMNKE----GLNSVIKPT 168 Query: 210 SCKPVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNINEDVIKRLCEXXXXXXXXXX 389 KPVPDE N TDVE +++++ ND L+EVNLNN++NI +K E Sbjct: 169 QYKPVPDEEPNSTDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKK 228 Query: 390 XXXXXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGLLELRV 569 ++ +L++N L+TLN+ESN+++G I++L+ A+ S L+E+++ Sbjct: 229 FSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTS-LVEMKI 287 Query: 570 VNQQQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVDKKTRQNRLV 749 NQ Q LG +VE EI ++++N TL G R+R + + MN + R+ RL Sbjct: 288 DNQSQP-LGNKVEMEIVSMLEKNATLLKFGYHFTQQGPRLRASNAM-MNNNDLVRKRRLA 345 Query: 750 N 752 + Sbjct: 346 D 346
>sp|Q9JHJ0|TMOD3_MOUSE Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod) Length = 352 Score = 122 bits (306), Expect = 2e-27 Identities = 80/246 (32%), Positives = 130/246 (52%), Gaps = 5/246 (2%) Frame = +3 Query: 36 MEFDTEFDEALKNATEEELVDLAAVLGFNGMLNQTQY-----HASVENKEQMCGGFQGVA 200 + D E +EAL +A++ EL DLAA+LG + ++ T + ++ N+E+ F V Sbjct: 113 ISLDPELEEALTSASDTELCDLAAILGMHNLIADTPFCDVLGSSNGVNQER----FPNVV 168 Query: 201 KYESCKPVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNINEDVIKRLCEXXXXXXX 380 K E PV DEP N T+VE +K++ ND+ L EVNLNN+KNI +K + Sbjct: 169 KGEKILPVFDEPPNPTNVEESLKRIRENDARLVEVNLNNIKNIPIPTLKDFAKTLEANTH 228 Query: 381 XXXXXXXXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGLLE 560 ++ F +L+ N L++LN+ESN++ G ++ LI A+ R+ L+E Sbjct: 229 VKHFSLAATRSNDPVAVAFADMLKVNKTLKSLNMESNFITGAGVLALIDAL-RDNETLME 287 Query: 561 LRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVDKKTRQN 740 L++ NQ+Q+ LG VE E+ ++++ENT + G R R + + N D R+ Sbjct: 288 LKIDNQRQQ-LGTSVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNND-LVRKR 345 Query: 741 RLVNKH 758 R+ H Sbjct: 346 RIEGDH 351
>sp|Q9NYL9|TMOD3_HUMAN Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod) Length = 352 Score = 121 bits (303), Expect = 4e-27 Identities = 81/244 (33%), Positives = 127/244 (52%), Gaps = 3/244 (1%) Frame = +3 Query: 36 MEFDTEFDEALKNATEEELVDLAAVLGFNGMLNQTQY---HASVENKEQMCGGFQGVAKY 206 + D E +EAL +A++ EL DLAA+LG + ++ T++ S +Q F V K Sbjct: 113 VSLDPELEEALTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQE--HFSNVVKG 170 Query: 207 ESCKPVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNINEDVIKRLCEXXXXXXXXX 386 E PV DEP N T+VE +K+ + ND+ L EVNLNN+KNI +K + Sbjct: 171 EKILPVFDEPPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVK 230 Query: 387 XXXXXXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGLLELR 566 ++ F +L+ N L++LN+ESN++ G I+ LI A+ R+ L EL+ Sbjct: 231 CFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFITGVGILALIDAL-RDNETLAELK 289 Query: 567 VVNQQQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVDKKTRQNRL 746 + NQ+Q+ LG VE E+ ++++ENT + G R R + + N D R+ R+ Sbjct: 290 IDNQRQQ-LGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNND-LVRKRRV 347 Query: 747 VNKH 758 H Sbjct: 348 EGDH 351
>sp|Q9JLH8|TMOD4_MOUSE Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod) Length = 345 Score = 118 bits (295), Expect = 3e-26 Identities = 71/235 (30%), Positives = 129/235 (54%), Gaps = 2/235 (0%) Frame = +3 Query: 45 DTEFDEALKNATEEELVDLAAVLGFNGMLNQTQYHASVENKEQMCG--GFQGVAKYESCK 218 + E +EAL +AT+ E+ D+AA+LG +++ QY+ ++ + E +C G V + + K Sbjct: 113 EPELEEALSHATDAEMCDIAAILGMYTLMSNKQYYDAICSGE-ICNTEGISSVVQPDKYK 171 Query: 219 PVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNINEDVIKRLCEXXXXXXXXXXXXX 398 PVPDEP N T++E ++K++ +ND L+EVNLNN+++I V+ LCE Sbjct: 172 PVPDEPPNPTNIEEMLKRVRSNDKELEEVNLNNIQDIPIPVLSDLCEAMKTNTYVRSFSL 231 Query: 399 XXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGLLELRVVNQ 578 + + +L +N L++LN+ESN+++ ++ ++ A+ RE + L ELRV NQ Sbjct: 232 VATKSGDPIANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAV-RENATLTELRVDNQ 290 Query: 579 QQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVDKKTRQNR 743 +Q G VE E+ ++++ ++ G R R + N + + +Q + Sbjct: 291 RQWP-GDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAAHAMTRNNELRRQQKK 344
>sp|Q9NZQ9|TMOD4_HUMAN Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod) Length = 345 Score = 115 bits (287), Expect = 3e-25 Identities = 69/235 (29%), Positives = 128/235 (54%), Gaps = 2/235 (0%) Frame = +3 Query: 45 DTEFDEALKNATEEELVDLAAVLGFNGMLNQTQYHASVENKEQMCG--GFQGVAKYESCK 218 + E +EAL +AT+ E+ D+AA+L +++ QY+ ++ + E +C G V + + K Sbjct: 113 EPELEEALAHATDAEMCDIAAILDMYTLMSNKQYYDALCSGE-ICNTEGISSVVQPDKYK 171 Query: 219 PVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNINEDVIKRLCEXXXXXXXXXXXXX 398 PVPDEP N T++E ++K++ +ND L+EVNLNN+++I ++ LCE Sbjct: 172 PVPDEPPNPTNIEEILKRVRSNDKELEEVNLNNIQDIPIPMLSELCEAMKANTYVRSFSL 231 Query: 399 XXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGLLELRVVNQ 578 + + +L +N L++LN+ESN+++ ++ ++ A+ RE + L ELRV NQ Sbjct: 232 VATRSGDPIANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAV-RENATLTELRVDNQ 290 Query: 579 QQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVDKKTRQNR 743 +Q G VE E+ ++++ ++ G R R + N + + +Q + Sbjct: 291 RQWP-GDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAAQAMTRNNELRRQQKK 344
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 94,063,371 Number of Sequences: 369166 Number of extensions: 1613028 Number of successful extensions: 4875 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4709 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4848 length of database: 68,354,980 effective HSP length: 111 effective length of database: 47,849,395 effective search space used: 10526866900 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)