Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_C12
(694 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P29536|LMD1_HUMAN Leiomodin-1 (Leiomodin, muscle form) (... 69 9e-12
sp|Q9JHJ0|TMOD3_MOUSE Tropomodulin-3 (Ubiquitous tropomodul... 67 3e-11
sp|Q9NYL9|TMOD3_HUMAN Tropomodulin-3 (Ubiquitous tropomodul... 67 6e-11
sp|P49813|TMOD1_MOUSE Tropomodulin-1 (Erythrocyte tropomodu... 67 6e-11
sp|Q9JKK7|TMOD2_MOUSE Tropomodulin-2 (Neuronal tropomodulin... 66 1e-10
sp|P70566|TMOD2_RAT Tropomodulin-2 (Neuronal tropomodulin) ... 65 1e-10
sp|P70567|TMOD1_RAT Tropomodulin-1 (Erythrocyte tropomoduli... 65 2e-10
sp|P28289|TMOD1_HUMAN Tropomodulin-1 (Erythrocyte tropomodu... 64 3e-10
sp|Q9NZR1|TMOD2_HUMAN Tropomodulin-2 (Neuronal tropomodulin... 63 6e-10
sp|Q9NZQ9|TMOD4_HUMAN Tropomodulin-4 (Skeletal muscle tropo... 53 7e-07
>sp|P29536|LMD1_HUMAN Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64
kDa autoantigen 1D) (64 kDa autoantigen 1D3)
(Thyroid-associated ophthalmopathy autoantigen) (Smooth
muscle leiomodin) (SM-Lmod)
Length = 572
Score = 69.3 bits (168), Expect = 9e-12
Identities = 50/153 (32%), Positives = 81/153 (52%), Gaps = 5/153 (3%)
Frame = +2
Query: 2 VNLNNLKNINEDVIKRLCEXXXXXXXXXXXXXXXIGLSNSGCDYFV-----VLLEKNDHL 166
VN+NN I +++ R E L+N+ D V ++L+ N +
Sbjct: 307 VNVNNSDCITNEILVRFTEALEFNTVVKL-----FALANTRADDHVAFAIAIMLKANKTI 361
Query: 167 ETLNLESNYLNGDSIIKLITAINREKSGLLELRVVNQQQKVLGVRVEQEINRLIKENTTL 346
+LNL+SN++ G I+ + A+ + + L ELR NQ+ + G + E EI +L+KENT+L
Sbjct: 362 TSLNLDSNHITGKGILAIFRALLQNNT-LTELRFHNQRH-ICGGKTEMEIAKLLKENTSL 419
Query: 347 QVLGVDLETADARIRIRDHLAMNVDKKTRQNRL 445
LG E A R+ + + L+ N+DK+ RQ RL
Sbjct: 420 LKLGYHFELAGPRMTVTNLLSRNMDKQ-RQKRL 451
>sp|Q9JHJ0|TMOD3_MOUSE Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod)
Length = 352
Score = 67.4 bits (163), Expect = 3e-11
Identities = 45/152 (29%), Positives = 76/152 (50%)
Frame = +2
Query: 2 VNLNNLKNINEDVIKRLCEXXXXXXXXXXXXXXXIGLSNSGCDYFVVLLEKNDHLETLNL 181
VNLNN+KNI +K + ++ F +L+ N L++LN+
Sbjct: 203 VNLNNIKNIPIPTLKDFAKTLEANTHVKHFSLAATRSNDPVAVAFADMLKVNKTLKSLNM 262
Query: 182 ESNYLNGDSIIKLITAINREKSGLLELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGV 361
ESN++ G ++ LI A+ R+ L+EL++ NQ+Q+ LG VE E+ ++++ENT + G
Sbjct: 263 ESNFITGAGVLALIDAL-RDNETLMELKIDNQRQQ-LGTSVELEMAKMLEENTNILKFGY 320
Query: 362 DLETADARIRIRDHLAMNVDKKTRQNRLVNKH 457
R R + + N D R+ R+ H
Sbjct: 321 QFTQQGPRTRAANAITKNND-LVRKRRIEGDH 351
>sp|Q9NYL9|TMOD3_HUMAN Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod)
Length = 352
Score = 66.6 bits (161), Expect = 6e-11
Identities = 46/152 (30%), Positives = 75/152 (49%)
Frame = +2
Query: 2 VNLNNLKNINEDVIKRLCEXXXXXXXXXXXXXXXIGLSNSGCDYFVVLLEKNDHLETLNL 181
VNLNN+KNI +K + ++ F +L+ N L++LN+
Sbjct: 203 VNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNV 262
Query: 182 ESNYLNGDSIIKLITAINREKSGLLELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGV 361
ESN++ G I+ LI A+ R+ L EL++ NQ+Q+ LG VE E+ ++++ENT + G
Sbjct: 263 ESNFITGVGILALIDAL-RDNETLAELKIDNQRQQ-LGTAVELEMAKMLEENTNILKFGY 320
Query: 362 DLETADARIRIRDHLAMNVDKKTRQNRLVNKH 457
R R + + N D R+ R+ H
Sbjct: 321 QFTQQGPRTRAANAITKNND-LVRKRRVEGDH 351
>sp|P49813|TMOD1_MOUSE Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod)
Length = 359
Score = 66.6 bits (161), Expect = 6e-11
Identities = 47/150 (31%), Positives = 76/150 (50%)
Frame = +2
Query: 2 VNLNNLKNINEDVIKRLCEXXXXXXXXXXXXXXXIGLSNSGCDYFVVLLEKNDHLETLNL 181
VNLNN++NI +K E ++ +L+ N L+TLN+
Sbjct: 200 VNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVAFALAEMLKVNKVLKTLNV 259
Query: 182 ESNYLNGDSIIKLITAINREKSGLLELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGV 361
ESN+++G I++L+ A+ S L+EL++ NQ Q LG +VE EI ++++NTTL G
Sbjct: 260 ESNFISGAGILRLVEALPHNTS-LVELKIDNQSQP-LGNKVEMEIVNMLEKNTTLLKFGY 317
Query: 362 DLETADARIRIRDHLAMNVDKKTRQNRLVN 451
R+R + + N D R+ RL +
Sbjct: 318 HFTQQGPRLRASNAMMSNND-LVRKRRLAD 346
>sp|Q9JKK7|TMOD2_MOUSE Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod)
Length = 351
Score = 65.9 bits (159), Expect = 1e-10
Identities = 42/140 (30%), Positives = 70/140 (50%)
Frame = +2
Query: 2 VNLNNLKNINEDVIKRLCEXXXXXXXXXXXXXXXIGLSNSGCDYFVVLLEKNDHLETLNL 181
VNLNN+KNI +K + ++ F +L+ N L++LN+
Sbjct: 202 VNLNNIKNIPIPTLKEFAKSLETNTHVKKFSLAATRSNDPVALAFAEMLKVNKTLKSLNV 261
Query: 182 ESNYLNGDSIIKLITAINREKSGLLELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGV 361
ESN++ G I+ L+ A+ RE L E+++ NQ+Q+ LG VE EI ++++EN+ + G
Sbjct: 262 ESNFITGTGILALVEAL-RENDTLTEIKIDNQRQQ-LGTAVEMEIAQMLEENSRILKFGY 319
Query: 362 DLETADARIRIRDHLAMNVD 421
R R+ + N D
Sbjct: 320 QFTKQGPRTRVAAAITKNND 339
>sp|P70566|TMOD2_RAT Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod)
Length = 351
Score = 65.5 bits (158), Expect = 1e-10
Identities = 42/140 (30%), Positives = 70/140 (50%)
Frame = +2
Query: 2 VNLNNLKNINEDVIKRLCEXXXXXXXXXXXXXXXIGLSNSGCDYFVVLLEKNDHLETLNL 181
VNLNN+KNI +K + ++ F +L+ N L++LN+
Sbjct: 202 VNLNNIKNIPIPTLKEFAKALETNTHVRKFSLAATRSNDPVALAFAEMLKVNKTLKSLNV 261
Query: 182 ESNYLNGDSIIKLITAINREKSGLLELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGV 361
ESN++ G I+ L+ A+ RE L E+++ NQ+Q+ LG VE EI ++++EN+ + G
Sbjct: 262 ESNFITGAGILALVEAL-RENDTLTEIKIDNQRQQ-LGTAVEMEIAQMLEENSRILKFGY 319
Query: 362 DLETADARIRIRDHLAMNVD 421
R R+ + N D
Sbjct: 320 QFTKQGPRTRVAAAITKNND 339
>sp|P70567|TMOD1_RAT Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod)
Length = 359
Score = 65.1 bits (157), Expect = 2e-10
Identities = 47/150 (31%), Positives = 76/150 (50%)
Frame = +2
Query: 2 VNLNNLKNINEDVIKRLCEXXXXXXXXXXXXXXXIGLSNSGCDYFVVLLEKNDHLETLNL 181
VNLNN++NI +K E ++ +L+ N L+TLN+
Sbjct: 200 VNLNNIRNIPIPTLKAYAESLKENSYVKKFSIVGTRSNDPVAFALAEMLKVNKVLKTLNV 259
Query: 182 ESNYLNGDSIIKLITAINREKSGLLELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGV 361
ESN+++G I+ L+ A+ S L+EL++ NQ Q LG +VE EI ++++NTTL G
Sbjct: 260 ESNFISGAGILCLVEALPHNTS-LVELKIDNQSQP-LGNKVEMEIVNMLEKNTTLLKFGY 317
Query: 362 DLETADARIRIRDHLAMNVDKKTRQNRLVN 451
R+R + + MN + R+ RL +
Sbjct: 318 HFTQQGPRLRASNAM-MNNNDLVRKRRLAD 346
>sp|P28289|TMOD1_HUMAN Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod)
Length = 359
Score = 64.3 bits (155), Expect = 3e-10
Identities = 45/150 (30%), Positives = 77/150 (51%)
Frame = +2
Query: 2 VNLNNLKNINEDVIKRLCEXXXXXXXXXXXXXXXIGLSNSGCDYFVVLLEKNDHLETLNL 181
VNLNN++NI +K E ++ +L++N L+TLN+
Sbjct: 200 VNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNV 259
Query: 182 ESNYLNGDSIIKLITAINREKSGLLELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGV 361
ESN+++G I++L+ A+ S L+E+++ NQ Q LG +VE EI ++++N TL G
Sbjct: 260 ESNFISGAGILRLVEALPYNTS-LVEMKIDNQSQP-LGNKVEMEIVSMLEKNATLLKFGY 317
Query: 362 DLETADARIRIRDHLAMNVDKKTRQNRLVN 451
R+R + + MN + R+ RL +
Sbjct: 318 HFTQQGPRLRASNAM-MNNNDLVRKRRLAD 346
>sp|Q9NZR1|TMOD2_HUMAN Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod)
Length = 351
Score = 63.2 bits (152), Expect = 6e-10
Identities = 40/140 (28%), Positives = 69/140 (49%)
Frame = +2
Query: 2 VNLNNLKNINEDVIKRLCEXXXXXXXXXXXXXXXIGLSNSGCDYFVVLLEKNDHLETLNL 181
VNLNN+KNI ++ + ++ F +L+ N L +LN+
Sbjct: 202 VNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNI 261
Query: 182 ESNYLNGDSIIKLITAINREKSGLLELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGV 361
ESN++ G I+ L+ A+ +E L E+++ NQ+Q+ LG VE EI ++++EN+ + G
Sbjct: 262 ESNFITGTGILALVEAL-KENDTLTEIKIDNQRQQ-LGTAVEMEIAQMLEENSRILKFGY 319
Query: 362 DLETADARIRIRDHLAMNVD 421
R R+ + N D
Sbjct: 320 QFTKQGPRTRVAAAITKNND 339
>sp|Q9NZQ9|TMOD4_HUMAN Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod)
Length = 345
Score = 53.1 bits (126), Expect = 7e-07
Identities = 37/147 (25%), Positives = 71/147 (48%)
Frame = +2
Query: 2 VNLNNLKNINEDVIKRLCEXXXXXXXXXXXXXXXIGLSNSGCDYFVVLLEKNDHLETLNL 181
VNLNN+++I ++ LCE + + +L +N L++LN+
Sbjct: 200 VNLNNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSGDPIANAVADMLRENRSLQSLNI 259
Query: 182 ESNYLNGDSIIKLITAINREKSGLLELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGV 361
ESN+++ ++ ++ A+ RE + L ELRV NQ+Q G VE E+ ++++ ++ G
Sbjct: 260 ESNFISSTGLMAVLKAV-RENATLTELRVDNQRQWP-GDAVEMEMATVLEQCPSIVRFGY 317
Query: 362 DLETADARIRIRDHLAMNVDKKTRQNR 442
R R + N + + +Q +
Sbjct: 318 HFTQQGPRARAAQAMTRNNELRRQQKK 344
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,245,051
Number of Sequences: 369166
Number of extensions: 994263
Number of successful extensions: 2624
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2567
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2607
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5976365205
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)