Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_O12
(808 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9JKK7|TMOD2_MOUSE Tropomodulin-2 (Neuronal tropomodulin... 101 3e-21
sp|P70566|TMOD2_RAT Tropomodulin-2 (Neuronal tropomodulin) ... 100 4e-21
sp|P49813|TMOD1_MOUSE Tropomodulin-1 (Erythrocyte tropomodu... 100 5e-21
sp|P70567|TMOD1_RAT Tropomodulin-1 (Erythrocyte tropomoduli... 99 2e-20
sp|Q9JHJ0|TMOD3_MOUSE Tropomodulin-3 (Ubiquitous tropomodul... 98 2e-20
sp|P28289|TMOD1_HUMAN Tropomodulin-1 (Erythrocyte tropomodu... 98 2e-20
sp|Q9NYL9|TMOD3_HUMAN Tropomodulin-3 (Ubiquitous tropomodul... 97 5e-20
sp|Q9NZR1|TMOD2_HUMAN Tropomodulin-2 (Neuronal tropomodulin... 97 5e-20
sp|Q9NZQ9|TMOD4_HUMAN Tropomodulin-4 (Skeletal muscle tropo... 91 3e-18
sp|Q9JLH8|TMOD4_MOUSE Tropomodulin-4 (Skeletal muscle tropo... 91 5e-18
>sp|Q9JKK7|TMOD2_MOUSE Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod)
Length = 351
Score = 101 bits (251), Expect = 3e-21
Identities = 60/176 (34%), Positives = 97/176 (55%)
Frame = +2
Query: 8 VAKYESCKPVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNISEDVIKRLCEXXXXX 187
V K E KPV +EP N T+VE+ +++++AND SL+EVNLNN+KNI +K +
Sbjct: 166 VVKGEKAKPVFEEPPNPTNVEASLQQMKANDPSLQEVNLNNIKNIPIPTLKEFAKSLETN 225
Query: 188 XXXXXXXXXXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGL 367
++ F +L+ N L++LN+ESN++ G I+ L+ A+ RE L
Sbjct: 226 THVKKFSLAATRSNDPVALAFAEMLKVNKTLKSLNVESNFITGTGILALVEAL-RENDTL 284
Query: 368 LELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVD 535
E+++ NQ+Q+ LG VE EI ++++EN+ + G R R+ + N D
Sbjct: 285 TEIKIDNQRQQ-LGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNND 339
>sp|P70566|TMOD2_RAT Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod)
Length = 351
Score = 100 bits (250), Expect = 4e-21
Identities = 60/176 (34%), Positives = 97/176 (55%)
Frame = +2
Query: 8 VAKYESCKPVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNISEDVIKRLCEXXXXX 187
V K E KPV +EP N T+VE+ +++++AND SL+EVNLNN+KNI +K +
Sbjct: 166 VVKGEKAKPVFEEPPNPTNVEASLQQMKANDPSLQEVNLNNIKNIPIPTLKEFAKALETN 225
Query: 188 XXXXXXXXXXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGL 367
++ F +L+ N L++LN+ESN++ G I+ L+ A+ RE L
Sbjct: 226 THVRKFSLAATRSNDPVALAFAEMLKVNKTLKSLNVESNFITGAGILALVEAL-RENDTL 284
Query: 368 LELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVD 535
E+++ NQ+Q+ LG VE EI ++++EN+ + G R R+ + N D
Sbjct: 285 TEIKIDNQRQQ-LGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNND 339
>sp|P49813|TMOD1_MOUSE Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod)
Length = 359
Score = 100 bits (249), Expect = 5e-21
Identities = 64/186 (34%), Positives = 99/186 (53%)
Frame = +2
Query: 8 VAKYESCKPVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNISEDVIKRLCEXXXXX 187
V K KPVPDE N TDVE +++++ ND L+EVNLNN++NI +K E
Sbjct: 164 VIKPTQYKPVPDEEPNSTDVEETLERIKNNDPELEEVNLNNIRNIPIPTLKAYAEALKEN 223
Query: 188 XXXXXXXXXXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGL 367
++ +L+ N L+TLN+ESN+++G I++L+ A+ S L
Sbjct: 224 SYVKKFSIVGTRSNDPVAFALAEMLKVNKVLKTLNVESNFISGAGILRLVEALPHNTS-L 282
Query: 368 LELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVDKKTR 547
+EL++ NQ Q LG +VE EI ++++NTTL G R+R + + N D R
Sbjct: 283 VELKIDNQSQP-LGNKVEMEIVNMLEKNTTLLKFGYHFTQQGPRLRASNAMMSNND-LVR 340
Query: 548 QNRLVN 565
+ RL +
Sbjct: 341 KRRLAD 346
>sp|P70567|TMOD1_RAT Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod)
Length = 359
Score = 98.6 bits (244), Expect = 2e-20
Identities = 64/186 (34%), Positives = 99/186 (53%)
Frame = +2
Query: 8 VAKYESCKPVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNISEDVIKRLCEXXXXX 187
V K KPVPDE N TDVE +++++ ND L+EVNLNN++NI +K E
Sbjct: 164 VIKPTQYKPVPDEEPNPTDVEETLERIKNNDPELEEVNLNNIRNIPIPTLKAYAESLKEN 223
Query: 188 XXXXXXXXXXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGL 367
++ +L+ N L+TLN+ESN+++G I+ L+ A+ S L
Sbjct: 224 SYVKKFSIVGTRSNDPVAFALAEMLKVNKVLKTLNVESNFISGAGILCLVEALPHNTS-L 282
Query: 368 LELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVDKKTR 547
+EL++ NQ Q LG +VE EI ++++NTTL G R+R + + MN + R
Sbjct: 283 VELKIDNQSQP-LGNKVEMEIVNMLEKNTTLLKFGYHFTQQGPRLRASNAM-MNNNDLVR 340
Query: 548 QNRLVN 565
+ RL +
Sbjct: 341 KRRLAD 346
>sp|Q9JHJ0|TMOD3_MOUSE Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod)
Length = 352
Score = 98.2 bits (243), Expect = 2e-20
Identities = 62/188 (32%), Positives = 98/188 (52%)
Frame = +2
Query: 8 VAKYESCKPVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNISEDVIKRLCEXXXXX 187
V K E PV DEP N T+VE +K++ ND+ L EVNLNN+KNI +K +
Sbjct: 167 VVKGEKILPVFDEPPNPTNVEESLKRIRENDARLVEVNLNNIKNIPIPTLKDFAKTLEAN 226
Query: 188 XXXXXXXXXXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGL 367
++ F +L+ N L++LN+ESN++ G ++ LI A+ R+ L
Sbjct: 227 THVKHFSLAATRSNDPVAVAFADMLKVNKTLKSLNMESNFITGAGVLALIDAL-RDNETL 285
Query: 368 LELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVDKKTR 547
+EL++ NQ+Q+ LG VE E+ ++++ENT + G R R + + N D R
Sbjct: 286 MELKIDNQRQQ-LGTSVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNND-LVR 343
Query: 548 QNRLVNKH 571
+ R+ H
Sbjct: 344 KRRIEGDH 351
>sp|P28289|TMOD1_HUMAN Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod)
Length = 359
Score = 98.2 bits (243), Expect = 2e-20
Identities = 62/186 (33%), Positives = 100/186 (53%)
Frame = +2
Query: 8 VAKYESCKPVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNISEDVIKRLCEXXXXX 187
V K KPVPDE N TDVE +++++ ND L+EVNLNN++NI +K E
Sbjct: 164 VIKPTQYKPVPDEEPNSTDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKEN 223
Query: 188 XXXXXXXXXXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGL 367
++ +L++N L+TLN+ESN+++G I++L+ A+ S L
Sbjct: 224 SYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTS-L 282
Query: 368 LELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVDKKTR 547
+E+++ NQ Q LG +VE EI ++++N TL G R+R + + MN + R
Sbjct: 283 VEMKIDNQSQP-LGNKVEMEIVSMLEKNATLLKFGYHFTQQGPRLRASNAM-MNNNDLVR 340
Query: 548 QNRLVN 565
+ RL +
Sbjct: 341 KRRLAD 346
>sp|Q9NYL9|TMOD3_HUMAN Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod)
Length = 352
Score = 97.1 bits (240), Expect = 5e-20
Identities = 63/190 (33%), Positives = 98/190 (51%)
Frame = +2
Query: 2 AGVAKYESCKPVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNISEDVIKRLCEXXX 181
+ V K E PV DEP N T+VE +K+ + ND+ L EVNLNN+KNI +K +
Sbjct: 165 SNVVKGEKILPVFDEPPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALE 224
Query: 182 XXXXXXXXXXXXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKS 361
++ F +L+ N L++LN+ESN++ G I+ LI A+ R+
Sbjct: 225 TNTHVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFITGVGILALIDAL-RDNE 283
Query: 362 GLLELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVDKK 541
L EL++ NQ+Q+ LG VE E+ ++++ENT + G R R + + N D
Sbjct: 284 TLAELKIDNQRQQ-LGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNND-L 341
Query: 542 TRQNRLVNKH 571
R+ R+ H
Sbjct: 342 VRKRRVEGDH 351
>sp|Q9NZR1|TMOD2_HUMAN Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod)
Length = 351
Score = 97.1 bits (240), Expect = 5e-20
Identities = 58/176 (32%), Positives = 95/176 (53%)
Frame = +2
Query: 8 VAKYESCKPVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNISEDVIKRLCEXXXXX 187
V K E KPV +EP N T+VE +++++AND SL+EVNLNN+KNI ++ +
Sbjct: 166 VVKGEKVKPVFEEPPNPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETN 225
Query: 188 XXXXXXXXXXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKSGL 367
++ F +L+ N L +LN+ESN++ G I+ L+ A+ +E L
Sbjct: 226 THVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEAL-KENDTL 284
Query: 368 LELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVD 535
E+++ NQ+Q+ LG VE EI ++++EN+ + G R R+ + N D
Sbjct: 285 TEIKIDNQRQQ-LGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNND 339
>sp|Q9NZQ9|TMOD4_HUMAN Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod)
Length = 345
Score = 91.3 bits (225), Expect = 3e-18
Identities = 53/185 (28%), Positives = 98/185 (52%)
Frame = +2
Query: 2 AGVAKYESCKPVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNISEDVIKRLCEXXX 181
+ V + + KPVPDEP N T++E ++K++ +ND L+EVNLNN+++I ++ LCE
Sbjct: 162 SSVVQPDKYKPVPDEPPNPTNIEEILKRVRSNDKELEEVNLNNIQDIPIPMLSELCEAMK 221
Query: 182 XXXXXXXXXXXXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKS 361
+ + +L +N L++LN+ESN+++ ++ ++ A+ RE +
Sbjct: 222 ANTYVRSFSLVATRSGDPIANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAV-RENA 280
Query: 362 GLLELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVDKK 541
L ELRV NQ+Q G VE E+ ++++ ++ G R R + N + +
Sbjct: 281 TLTELRVDNQRQWP-GDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAAQAMTRNNELR 339
Query: 542 TRQNR 556
+Q +
Sbjct: 340 RQQKK 344
>sp|Q9JLH8|TMOD4_MOUSE Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod)
Length = 345
Score = 90.5 bits (223), Expect = 5e-18
Identities = 54/185 (29%), Positives = 98/185 (52%)
Frame = +2
Query: 2 AGVAKYESCKPVPDEPDNDTDVESVIKKLEANDSSLKEVNLNNLKNISEDVIKRLCEXXX 181
+ V + + KPVPDEP N T++E ++K++ +ND L+EVNLNN+++I V+ LCE
Sbjct: 162 SSVVQPDKYKPVPDEPPNPTNIEEMLKRVRSNDKELEEVNLNNIQDIPIPVLSDLCEAMK 221
Query: 182 XXXXXXXXXXXXIGLSNSGCDHFVVLLEKNDHLETLNLESNYLNGDSIIKLITAINREKS 361
+ + +L +N L++LN+ESN+++ ++ ++ A+ RE +
Sbjct: 222 TNTYVRSFSLVATKSGDPIANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAV-RENA 280
Query: 362 GLLELRVVNQQQKVLGVRVEQEINRLIKENTTLQVLGVDLETADARIRIRDHLAMNVDKK 541
L ELRV NQ+Q G VE E+ ++++ ++ G R R + N + +
Sbjct: 281 TLTELRVDNQRQWP-GDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAAHAMTRNNELR 339
Query: 542 TRQNR 556
+Q +
Sbjct: 340 RQQKK 344
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,835,908
Number of Sequences: 369166
Number of extensions: 1182190
Number of successful extensions: 3790
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3687
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3771
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7666799535
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)