Planaria EST Database

DrC_00836

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00836
         (1276 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P40529|AGE2_YEAST  Protein AGE2                                119   2e-26
sp|Q96P47|CENG3_HUMAN  Centaurin-gamma 3                          106   2e-22
sp|Q96P50|CENB5_HUMAN  Centaurin-beta 5 (Cnt-b5)                  104   5e-22
sp|Q8BXK8|CENG2_MOUSE  Centaurin-gamma 2 (ARF-GAP with GTP-b...   104   5e-22
sp|Q9UPQ3|CENG2_HUMAN  Centaurin-gamma 2 (ARF-GAP with GTP-b...   103   1e-21
sp|Q15057|CENB2_HUMAN  Centaurin-beta 2 (Cnt-b2)                  102   2e-21
sp|Q9NGC3|CEG1A_DROME  Centaurin-gamma 1A                         102   3e-21
sp|Q15027|CENB1_HUMAN  Centaurin-beta 1 (Cnt-b1)                  100   9e-21
sp|O75689|CENA1_HUMAN  Centaurin-alpha 1 (Putative MAPK-acti...    99   3e-20
sp|O74345|UCP3_SCHPO  UBA-domain containing protein 3              98   4e-20

>sp|P40529|AGE2_YEAST Protein AGE2
          Length = 298

 Score =  119 bits (298), Expect = 2e-26
 Identities = 99/357 (27%), Positives = 163/357 (45%), Gaps = 9/357 (2%)
 Frame = +3

Query: 27   LAELLKDDDNKYCVDCDSK-GPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWT 203
            L+ LL+D  N +C DC ++  PRWASW+LG+F+CI+CAGIHR+LG H+S+VKSV+LD+W 
Sbjct: 11   LSALLRDPGNSHCADCKAQLHPRWASWSLGVFICIKCAGIHRSLGTHISKVKSVDLDTWK 70

Query: 204  PQQVAMMKEIGNS-RGRAIYEANLEDNFR-RPQTD-SSLEQFIRSKYEHKRYIAKEWIPP 374
             + +  + +  N+ R  + YEA L D  + R  TD SSL+ FI++KYE+K+     WI  
Sbjct: 71   EEHLVKLIQFKNNLRANSYYEATLADELKQRKITDTSSLQNFIKNKYEYKK-----WIGD 125

Query: 375  TPTVDVIAEEIRKLEQNQNKKRVNYNNTVTNAIIPLS----RRDNIETPGNIKSIEIDDK 542
              +++ + +     E   +K   N++   +NA +  S    ++   + P ++ S    + 
Sbjct: 126  LSSIEGLND---STEPVLHKPSANHSLPASNARLDQSSNSLQKTQTQPPSHLLSTSRSNT 182

Query: 543  SQPVVNNKIDLLGLESDNVTNNIDDAFGDFVFAAQPTISTCQTVTGSATKPVTVSSAVDD 722
            S  ++N ++  L   + N                        +VT SAT   ++ +A   
Sbjct: 183  S--LLNLQVSSLSKTTSNT-----------------------SVTSSAT---SIGAA--- 211

Query: 723  XXXXXXXXXXXXXXXPGNNIAPSVSTSSAIPNISGKLD-KSSILALYNNSSSTMNTMGQM 899
                                  +  T + +     + D K SIL+LY+  S+   +    
Sbjct: 212  ----------------------NTKTGNRVGEFGQRNDLKKSILSLYSKPSAQTQSQNSF 249

Query: 900  PNSTTWPNAGAPAYQSNLMQSDFQSQGYAMSGNNWMVPGQMNANSAFGVQHNPFFNN 1070
              STT      P        S F + G   + NN M     N++S   +  N  F N
Sbjct: 250  FTSTTPQPCNTP--------SPFVNTGITATNNNSM---NSNSSSNISLDDNELFKN 295

>sp|Q96P47|CENG3_HUMAN Centaurin-gamma 3
          Length = 876

 Score =  106 bits (264), Expect = 2e-22
 Identities = 50/116 (43%), Positives = 76/116 (65%), Gaps = 3/116 (2%)
 Frame = +3

Query: 54  NKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEI 233
           N +C+DCD+  P WAS  LG  +CI C+GIHR+LG HLSRV+S++LD W P+ +A+M  +
Sbjct: 639 NSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLDDWPPELLAVMTAM 698

Query: 234 GNSRGRAIYEANLEDNFRRPQTDS---SLEQFIRSKYEHKRYIAKEWIPPTPTVDV 392
           GN+   +++E  L   + +P  D+     E++IR+KYE K ++A     P P+ DV
Sbjct: 699 GNALANSVWEGAL-GGYSKPGPDACREEKERWIRAKYEQKLFLA-----PLPSSDV 748

>sp|Q96P50|CENB5_HUMAN Centaurin-beta 5 (Cnt-b5)
          Length = 759

 Score =  104 bits (260), Expect = 5e-22
 Identities = 52/111 (46%), Positives = 68/111 (61%), Gaps = 4/111 (3%)
 Frame = +3

Query: 54  NKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEI 233
           N  C DC    PRWAS  LG+ LCI C+GIHR+LGVH S+V+S+ LDSW P+ + +M E+
Sbjct: 373 NSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSLTLDSWEPELLKLMCEL 432

Query: 234 GNSRGRAIYEANLEDNFRRPQTDSSLEQ----FIRSKYEHKRYIAKEWIPP 374
           GNS    IYEA  E    R  T SS  Q    +I+ KY  K+++ K  + P
Sbjct: 433 GNSAVNQIYEAQCEGAGSRKPTASSSRQDKEAWIKDKYVEKKFLRKAPMAP 483

>sp|Q8BXK8|CENG2_MOUSE Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin
           repeat and pleckstrin homology domains 1) (AGAP1)
          Length = 857

 Score =  104 bits (260), Expect = 5e-22
 Identities = 47/104 (45%), Positives = 69/104 (66%), Gaps = 3/104 (2%)
 Frame = +3

Query: 54  NKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEI 233
           N +CVDCD++ P WAS  LG  +CI C+GIHRNLG HLSRV+S++LD W  + + +M  I
Sbjct: 621 NSHCVDCDTQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPMELIKVMSSI 680

Query: 234 GNSRGRAIYEANLEDNFRRPQTDSSLEQ---FIRSKYEHKRYIA 356
           GN    +++E   +    +P  DS+ E+   +IR+KYE K ++A
Sbjct: 681 GNELANSVWEEGSQGR-TKPSLDSTREEKERWIRAKYEQKLFLA 723

>sp|Q9UPQ3|CENG2_HUMAN Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin
           repeat and pleckstrin homology domains 1) (AGAP1)
          Length = 857

 Score =  103 bits (257), Expect = 1e-21
 Identities = 46/104 (44%), Positives = 70/104 (67%), Gaps = 3/104 (2%)
 Frame = +3

Query: 54  NKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEI 233
           N +CVDC+++ P WAS  LG  +CI C+GIHRNLG HLSRV+S++LD W  + + +M  I
Sbjct: 621 NSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSI 680

Query: 234 GNSRGRAIYEANLEDNFRRPQTDSSLEQ---FIRSKYEHKRYIA 356
           GN    +++E + +    +P  DS+ E+   +IR+KYE K ++A
Sbjct: 681 GNELANSVWEESSQGR-TKPSVDSTREEKERWIRAKYEQKLFLA 723

>sp|Q15057|CENB2_HUMAN Centaurin-beta 2 (Cnt-b2)
          Length = 778

 Score =  102 bits (255), Expect = 2e-21
 Identities = 50/112 (44%), Positives = 72/112 (64%), Gaps = 3/112 (2%)
 Frame = +3

Query: 54  NKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEI 233
           N  C DC    PRWAS  LGI LCI C+GIHR+LGVH S+V+S+ LD+W P+ + +M E+
Sbjct: 411 NASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCEL 470

Query: 234 GNSRGRAIYEANLED-NFRRPQTDSSLEQ--FIRSKYEHKRYIAKEWIPPTP 380
           GN     +YEAN+E    ++PQ     E+  +IR+KY  ++++ K  I  +P
Sbjct: 471 GNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSP 522

>sp|Q9NGC3|CEG1A_DROME Centaurin-gamma 1A
          Length = 995

 Score =  102 bits (253), Expect = 3e-21
 Identities = 61/174 (35%), Positives = 96/174 (55%), Gaps = 9/174 (5%)
 Frame = +3

Query: 15   LQIILAELLKDDDNKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLD 194
            L  +LA   +   N +CVDC +  P WAS  LG+ +CI C+G+HRNLG H+S+V+S+ LD
Sbjct: 701  LAAMLAIRQRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLD 760

Query: 195  SWTPQQVAMMKEIGNSRGRAIYEANLEDNFRRPQTDSS---LEQFIRSKYEHKRYI---- 353
             W    +++M  IGNS   +++E+N      +P + +S    E+++RSKYE K ++    
Sbjct: 761  DWPSPHLSVMLAIGNSLANSVWESNTRQRV-KPTSQASREDKERWVRSKYEAKEFLTPLG 819

Query: 354  --AKEWIPPTPTVDVIAEEIRKLEQNQNKKRVNYNNTVTNAIIPLSRRDNIETP 509
              +     P+P   +I   IR   ++      N  + VTNA +  S RD + TP
Sbjct: 820  NGSSAHPSPSPGQQLIEAVIRADIKSIVSILANCPSEVTNANV--SARD-VRTP 870

>sp|Q15027|CENB1_HUMAN Centaurin-beta 1 (Cnt-b1)
          Length = 740

 Score =  100 bits (249), Expect = 9e-21
 Identities = 48/122 (39%), Positives = 75/122 (61%), Gaps = 1/122 (0%)
 Frame = +3

Query: 24  ILAELLKDDDNKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWT 203
           ++A++   D N  C DC    P WAS  LG+ LCI+C+GIHR+LGVH S+V+S+ LDSW 
Sbjct: 407 VVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWE 466

Query: 204 PQQVAMMKEIGNSRGRAIYEANLED-NFRRPQTDSSLEQFIRSKYEHKRYIAKEWIPPTP 380
           P+ V +M E+GN     IYEA +E    ++P    S ++  +  + H +Y+ K+++   P
Sbjct: 467 PELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQE--KEAWIHAKYVEKKFLTKLP 524

Query: 381 TV 386
            +
Sbjct: 525 EI 526

>sp|O75689|CENA1_HUMAN Centaurin-alpha 1 (Putative MAPK-activating protein PM25)
          Length = 374

 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 51/113 (45%), Positives = 71/113 (62%), Gaps = 3/113 (2%)
 Frame = +3

Query: 33  ELLKDDDNKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQ 212
           ELL+   N  C DC +  P WAS+TLG+F+C+ C+GIHRN+   +S+VKSV LD+W   Q
Sbjct: 11  ELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQ 69

Query: 213 VAMMKEIGNSRGRAIYEANLEDNFRRP-QTDSSL--EQFIRSKYEHKRYIAKE 362
           V  M   GN   RA +E+ +   + RP  +D  L  EQ+IR+KYE + +I  E
Sbjct: 70  VEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPE 122

>sp|O74345|UCP3_SCHPO UBA-domain containing protein 3
          Length = 601

 Score = 98.2 bits (243), Expect = 4e-20
 Identities = 44/103 (42%), Positives = 62/103 (60%), Gaps = 3/103 (2%)
 Frame = +3

Query: 54  NKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEI 233
           N  C DC ++G +WASW LGIFLC+RCA IHR LG H+S+VKS++LD W+  Q+  MK  
Sbjct: 20  NNLCADCSTRGVQWASWNLGIFLCLRCATIHRKLGTHVSKVKSISLDEWSNDQIEKMKHW 79

Query: 234 GNSRGRAIYEANLEDN---FRRPQTDSSLEQFIRSKYEHKRYI 353
           GN      +  N   +         +  +E++IR KYE K ++
Sbjct: 80  GNINANRYWNPNPLSHPLPTNALSDEHVMEKYIRDKYERKLFL 122

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 139,760,309
Number of Sequences: 369166
Number of extensions: 2911390
Number of successful extensions: 7904
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7392
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7869
length of database: 68,354,980
effective HSP length: 113
effective length of database: 47,479,925
effective search space used: 14766256675
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00836

  1. Dr_sW_021_D22
  2. Dr_sW_023_M17
  3. Dr_sW_018_I15
  4. Dr_sW_025_H08