Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_M17
(803 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P40529|AGE2_YEAST Protein AGE2 100 4e-21
sp|Q96P50|CENB5_HUMAN Centaurin-beta 5 (Cnt-b5) 93 7e-19
sp|Q15057|CENB2_HUMAN Centaurin-beta 2 (Cnt-b2) 92 2e-18
sp|Q96P47|CENG3_HUMAN Centaurin-gamma 3 88 2e-17
sp|Q9NGC3|CEG1A_DROME Centaurin-gamma 1A 86 9e-17
sp|Q9UPQ3|CENG2_HUMAN Centaurin-gamma 2 (ARF-GAP with GTP-b... 86 2e-16
sp|Q8BXK8|CENG2_MOUSE Centaurin-gamma 2 (ARF-GAP with GTP-b... 85 2e-16
sp|Q15027|CENB1_HUMAN Centaurin-beta 1 (Cnt-b1) 84 3e-16
sp|O74345|UCP3_SCHPO UBA-domain containing protein 3 84 3e-16
sp|O75689|CENA1_HUMAN Centaurin-alpha 1 (Putative MAPK-acti... 83 8e-16
>sp|P40529|AGE2_YEAST Protein AGE2
Length = 298
Score = 100 bits (250), Expect = 4e-21
Identities = 65/205 (31%), Positives = 112/205 (54%), Gaps = 7/205 (3%)
Frame = +3
Query: 3 RWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEIGNS-RGRAIYEA 179
RWASW+LG+F+CI+CAGIHR+LG H+S+VKSV+LD+W + + + + N+ R + YEA
Sbjct: 33 RWASWSLGVFICIKCAGIHRSLGTHISKVKSVDLDTWKEEHLVKLIQFKNNLRANSYYEA 92
Query: 180 NLEDNFR-RPQTD-SSLEQFIRSKYEHKRYIAKEWIPPTPTVDVIAEEIRKLEQNQNKKR 353
L D + R TD SSL+ FI++KYE+K+ WI +++ + + E +K
Sbjct: 93 TLADELKQRKITDTSSLQNFIKNKYEYKK-----WIGDLSSIEGLND---STEPVLHKPS 144
Query: 354 VNYNNTVTNAMIPLS----RRDNIETPGNIKSIEIDDKSQPVVNNKIDLLGLESDNVTNN 521
N++ +NA + S ++ + P ++ S + S ++N ++ L + N +
Sbjct: 145 ANHSLPASNARLDQSSNSLQKTQTQPPSHLLSTSRSNTS--LLNLQVSSLSKTTSNTS-- 200
Query: 522 IDDAFGDFVFAAQPTISTCQTVTGS 596
V ++ +I T TG+
Sbjct: 201 --------VTSSATSIGAANTKTGN 217
>sp|Q96P50|CENB5_HUMAN Centaurin-beta 5 (Cnt-b5)
Length = 759
Score = 93.2 bits (230), Expect = 7e-19
Identities = 47/99 (47%), Positives = 63/99 (63%), Gaps = 4/99 (4%)
Frame = +3
Query: 3 RWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEIGNSRGRAIYEAN 182
RWAS LG+ LCI C+GIHR+LGVH S+V+S+ LDSW P+ + +M E+GNS IYEA
Sbjct: 385 RWASINLGVLLCIECSGIHRSLGVHCSKVRSLTLDSWEPELLKLMCELGNSAVNQIYEAQ 444
Query: 183 LEDNFRRPQTDSSLEQ----FIRSKYEHKRYIAKEWIPP 287
E R T SS Q +I+ KY K+++ K + P
Sbjct: 445 CEGAGSRKPTASSSRQDKEAWIKDKYVEKKFLRKAPMAP 483
>sp|Q15057|CENB2_HUMAN Centaurin-beta 2 (Cnt-b2)
Length = 778
Score = 92.0 bits (227), Expect = 2e-18
Identities = 45/100 (45%), Positives = 67/100 (67%), Gaps = 3/100 (3%)
Frame = +3
Query: 3 RWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEIGNSRGRAIYEAN 182
RWAS LGI LCI C+GIHR+LGVH S+V+S+ LD+W P+ + +M E+GN +YEAN
Sbjct: 423 RWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYEAN 482
Query: 183 LED-NFRRPQTDSSLEQ--FIRSKYEHKRYIAKEWIPPTP 293
+E ++PQ E+ +IR+KY ++++ K I +P
Sbjct: 483 VEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSP 522
>sp|Q96P47|CENG3_HUMAN Centaurin-gamma 3
Length = 876
Score = 88.2 bits (217), Expect = 2e-17
Identities = 44/103 (42%), Positives = 67/103 (65%), Gaps = 3/103 (2%)
Frame = +3
Query: 6 WASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEIGNSRGRAIYEANL 185
WAS LG +CI C+GIHR+LG HLSRV+S++LD W P+ +A+M +GN+ +++E L
Sbjct: 652 WASLNLGALMCIECSGIHRHLGAHLSRVRSLDLDDWPPELLAVMTAMGNALANSVWEGAL 711
Query: 186 EDNFRRPQTDS---SLEQFIRSKYEHKRYIAKEWIPPTPTVDV 305
+ +P D+ E++IR+KYE K ++A P P+ DV
Sbjct: 712 -GGYSKPGPDACREEKERWIRAKYEQKLFLA-----PLPSSDV 748
>sp|Q9NGC3|CEG1A_DROME Centaurin-gamma 1A
Length = 995
Score = 86.3 bits (212), Expect = 9e-17
Identities = 52/148 (35%), Positives = 83/148 (56%), Gaps = 9/148 (6%)
Frame = +3
Query: 6 WASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEIGNSRGRAIYEANL 185
WAS LG+ +CI C+G+HRNLG H+S+V+S+ LD W +++M IGNS +++E+N
Sbjct: 727 WASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDDWPSPHLSVMLAIGNSLANSVWESNT 786
Query: 186 EDNFRRPQTDSS---LEQFIRSKYEHKRYI------AKEWIPPTPTVDVIAEEIRKLEQN 338
+P + +S E+++RSKYE K ++ + P+P +I IR ++
Sbjct: 787 RQRV-KPTSQASREDKERWVRSKYEAKEFLTPLGNGSSAHPSPSPGQQLIEAVIRADIKS 845
Query: 339 QNKKRVNYNNTVTNAMIPLSRRDNIETP 422
N + VTNA + S RD + TP
Sbjct: 846 IVSILANCPSEVTNANV--SARD-VRTP 870
>sp|Q9UPQ3|CENG2_HUMAN Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin
repeat and pleckstrin homology domains 1) (AGAP1)
Length = 857
Score = 85.5 bits (210), Expect = 2e-16
Identities = 40/91 (43%), Positives = 60/91 (65%), Gaps = 3/91 (3%)
Frame = +3
Query: 6 WASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEIGNSRGRAIYEANL 185
WAS LG +CI C+GIHRNLG HLSRV+S++LD W + + +M IGN +++E +
Sbjct: 634 WASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESS 693
Query: 186 EDNFRRPQTDSSLEQ---FIRSKYEHKRYIA 269
+ +P DS+ E+ +IR+KYE K ++A
Sbjct: 694 QGR-TKPSVDSTREEKERWIRAKYEQKLFLA 723
>sp|Q8BXK8|CENG2_MOUSE Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin
repeat and pleckstrin homology domains 1) (AGAP1)
Length = 857
Score = 85.1 bits (209), Expect = 2e-16
Identities = 40/91 (43%), Positives = 59/91 (64%), Gaps = 3/91 (3%)
Frame = +3
Query: 6 WASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEIGNSRGRAIYEANL 185
WAS LG +CI C+GIHRNLG HLSRV+S++LD W + + +M IGN +++E
Sbjct: 634 WASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPMELIKVMSSIGNELANSVWEEGS 693
Query: 186 EDNFRRPQTDSSLEQ---FIRSKYEHKRYIA 269
+ +P DS+ E+ +IR+KYE K ++A
Sbjct: 694 QGR-TKPSLDSTREEKERWIRAKYEQKLFLA 723
>sp|Q15027|CENB1_HUMAN Centaurin-beta 1 (Cnt-b1)
Length = 740
Score = 84.3 bits (207), Expect = 3e-16
Identities = 41/99 (41%), Positives = 64/99 (64%), Gaps = 1/99 (1%)
Frame = +3
Query: 6 WASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEIGNSRGRAIYEANL 185
WAS LG+ LCI+C+GIHR+LGVH S+V+S+ LDSW P+ V +M E+GN IYEA +
Sbjct: 430 WASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARV 489
Query: 186 ED-NFRRPQTDSSLEQFIRSKYEHKRYIAKEWIPPTPTV 299
E ++P S ++ + + H +Y+ K+++ P +
Sbjct: 490 EAMAVKKPGPSCSRQE--KEAWIHAKYVEKKFLTKLPEI 526
>sp|O74345|UCP3_SCHPO UBA-domain containing protein 3
Length = 601
Score = 84.3 bits (207), Expect = 3e-16
Identities = 39/91 (42%), Positives = 55/91 (60%), Gaps = 3/91 (3%)
Frame = +3
Query: 3 RWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEIGNSRGRAIYEAN 182
+WASW LGIFLC+RCA IHR LG H+S+VKS++LD W+ Q+ MK GN + N
Sbjct: 32 QWASWNLGIFLCLRCATIHRKLGTHVSKVKSISLDEWSNDQIEKMKHWGNINANRYWNPN 91
Query: 183 LEDN---FRRPQTDSSLEQFIRSKYEHKRYI 266
+ + +E++IR KYE K ++
Sbjct: 92 PLSHPLPTNALSDEHVMEKYIRDKYERKLFL 122
>sp|O75689|CENA1_HUMAN Centaurin-alpha 1 (Putative MAPK-activating protein PM25)
Length = 374
Score = 83.2 bits (204), Expect = 8e-16
Identities = 43/93 (46%), Positives = 61/93 (65%), Gaps = 3/93 (3%)
Frame = +3
Query: 6 WASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEIGNSRGRAIYEANL 185
WAS+TLG+F+C+ C+GIHRN+ +S+VKSV LD+W QV M GN RA +E+ +
Sbjct: 31 WASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKV 89
Query: 186 EDNFRRP-QTDSSL--EQFIRSKYEHKRYIAKE 275
+ RP +D L EQ+IR+KYE + +I E
Sbjct: 90 PSFYYRPTPSDCQLLREQWIRAKYERQEFIYPE 122
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,460,819
Number of Sequences: 369166
Number of extensions: 1411186
Number of successful extensions: 4125
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3963
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4100
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7618580670
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)