Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_I15
(615 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26363|CFTR_XENLA Cystic fibrosis transmembrane conducta... 33 0.44
sp|P26362|CFTR_SQUAC Cystic fibrosis transmembrane conducta... 33 0.58
sp|Q89AJ0|ZNUC_BUCBP High-affinity zinc uptake system ATP-b... 33 0.58
sp|P22861|AMYG_DEBOC Glucoamylase 1 precursor (Glucan 1,4-a... 32 0.99
sp|Q7Z7M1|GP144_HUMAN Probable G-protein coupled receptor 1... 32 1.7
sp|Q5D1Z7|CFTR_TRIVU Cystic fibrosis transmembrane conducta... 32 1.7
sp|Q9H4W6|COE3_HUMAN Transcription factor COE3 (Early B-cel... 31 2.2
sp|Q14686|NCOA6_HUMAN Nuclear receptor coactivator 6 (Ampli... 31 2.9
sp|P83509|GRLF1_CANFA Glucocorticoid receptor DNA-binding f... 30 3.8
sp|O60563|CCNT1_HUMAN Cyclin-T1 (Cyclin-T) (CycT1) 30 4.9
>sp|P26363|CFTR_XENLA Cystic fibrosis transmembrane conductance regulator (CFTR)
(cAMP-dependent chloride channel)
Length = 1485
Score = 33.5 bits (75), Expect = 0.44
Identities = 20/91 (21%), Positives = 42/91 (46%)
Frame = +2
Query: 128 SVSTSSAIPNISGKLDKSSILALYNNSSSTMNTMGQMPNSTTWPNAGAPAYQSNLMQSDF 307
S+ + + NI+ K++K +LA+ ++ + ++ M P+AG + + S
Sbjct: 435 SLHVAPVLRNINFKIEKGQLLAIAGSTGAGKTSLLMMIMGELEPSAGKIKHSGRISFSPQ 494
Query: 308 QSQGYAMSGNNWMVPGQMNANSAFGVQHNPF 400
S W++PG + N FGV ++ +
Sbjct: 495 VS---------WIMPGTIKENIVFGVSYDQY 516
>sp|P26362|CFTR_SQUAC Cystic fibrosis transmembrane conductance regulator (CFTR)
(cAMP-dependent chloride channel)
Length = 1492
Score = 33.1 bits (74), Expect = 0.58
Identities = 22/96 (22%), Positives = 43/96 (44%)
Frame = +2
Query: 128 SVSTSSAIPNISGKLDKSSILALYNNSSSTMNTMGQMPNSTTWPNAGAPAYQSNLMQSDF 307
S+ + + NIS KL+K +LA+ ++ S +++ M P+ G + + S
Sbjct: 435 SLHVTPVLKNISFKLEKGELLAIAGSTGSGKSSLLMMIMGELEPSDGKIKHSGRISYSPQ 494
Query: 308 QSQGYAMSGNNWMVPGQMNANSAFGVQHNPFFNNSV 415
W++PG + N FG+ ++ + SV
Sbjct: 495 VP---------WIMPGTIKDNIIFGLSYDEYRYTSV 521
>sp|Q89AJ0|ZNUC_BUCBP High-affinity zinc uptake system ATP-binding protein znuC
Length = 238
Score = 33.1 bits (74), Expect = 0.58
Identities = 27/102 (26%), Positives = 46/102 (45%)
Frame = +2
Query: 113 NNIAPSVSTSSAIPNISGKLDKSSILALYNNSSSTMNTMGQMPNSTTWPNAGAPAYQSNL 292
NNI+ + + S + NIS L + IL L + + +T+ ++ PN G +++NL
Sbjct: 8 NNISVNFNNRSILSNISLALTPNCILTLIGPNGAGKSTLVRVILGLLKPNQGKIFFKNNL 67
Query: 293 MQSDFQSQGYAMSGNNWMVPGQMNANSAFGVQHNPFFNNSVF 418
GY +P ++N +S + N F N S F
Sbjct: 68 ------RIGY--------IPQKLNLHSTLPITVNRFMNLSYF 95
>sp|P22861|AMYG_DEBOC Glucoamylase 1 precursor (Glucan 1,4-alpha-glucosidase)
(1,4-alpha-D-glucan glucohydrolase)
Length = 958
Score = 32.3 bits (72), Expect = 0.99
Identities = 33/121 (27%), Positives = 56/121 (46%), Gaps = 8/121 (6%)
Frame = +2
Query: 131 VSTSSAIPNISGKLD---KSSILALYNNSSSTMNTMGQMPNSTTWPNAGAPAYQSNLMQS 301
VS +S +I + K+S + ++SSST++ M + N P Y MQ
Sbjct: 511 VSNASEWKSIQSSISATAKTSSTSSVSSSSSTIDYMNTLAPGKG--NINYPPYAIYNMQG 568
Query: 302 DFQSQGYAMSGNNWMVPG--QMNANSAFG-VQHNPFFNN--SVFPGQPAIPISQPTFPTS 466
D +A+S N G + + ++ +G +Q N ++ VFP + IS+ TFP +
Sbjct: 569 DSDLATHAVSPNATHADGTVEYDIHNLYGYLQENATYHALLEVFPNKRPFMISRSTFPRA 628
Query: 467 G 469
G
Sbjct: 629 G 629
>sp|Q7Z7M1|GP144_HUMAN Probable G-protein coupled receptor 144 (G-protein coupled receptor
PGR24)
Length = 963
Score = 31.6 bits (70), Expect = 1.7
Identities = 20/73 (27%), Positives = 34/73 (46%), Gaps = 2/73 (2%)
Frame = +2
Query: 257 PNAGAPAYQSNLMQSDFQSQ--GYAMSGNNWMVPGQMNANSAFGVQHNPFFNNSVFPGQP 430
P A A + ++N +Q +Q +S W V G++N F +QH + +FP P
Sbjct: 548 PQAPASSEEANRVQRFLSTQVGSAIISSEVWDVTGEVNVAMTFHLQHRA--QSPLFPPHP 605
Query: 431 AIPISQPTFPTSG 469
P + + T+G
Sbjct: 606 PSPYTGGAWATTG 618
>sp|Q5D1Z7|CFTR_TRIVU Cystic fibrosis transmembrane conductance regulator (CFTR)
(cAMP-dependent chloride channel)
Length = 1478
Score = 31.6 bits (70), Expect = 1.7
Identities = 22/96 (22%), Positives = 45/96 (46%)
Frame = +2
Query: 128 SVSTSSAIPNISGKLDKSSILALYNNSSSTMNTMGQMPNSTTWPNAGAPAYQSNLMQSDF 307
S+ + + NIS K++K +LA+ ++ + ++ + P+ G + + F
Sbjct: 434 SLLGTPVLKNISFKIEKGQLLAVAGSTGAGKTSLLMLIMGELEPSEGKIKHSGRI---SF 490
Query: 308 QSQGYAMSGNNWMVPGQMNANSAFGVQHNPFFNNSV 415
SQ +W++PG + N FGV ++ + SV
Sbjct: 491 CSQF------SWIMPGTIKENIIFGVSYDEYRYRSV 520
>sp|Q9H4W6|COE3_HUMAN Transcription factor COE3 (Early B-cell factor 3) (EBF-3)
(Olf-1/EBF-like 2) (OE-2) (O/E-2)
Length = 596
Score = 31.2 bits (69), Expect = 2.2
Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 1/126 (0%)
Frame = +2
Query: 113 NNIAPSVSTSSAIPNISGKLDKSSILALYNNSSSTMNTMGQMPNSTTWPNAGAPAYQSNL 292
+N P++ + A + G SS LA+ + +S N +T+ + S
Sbjct: 419 HNQIPTLGNNPAHTGMMGVNSFSSQLAVNVSETSQANDQVGYSRNTSSVSPRGYVPSSTP 478
Query: 293 MQSDFQSQGYAMSGNNWMVPGQMNANSAFGVQHNPFFNNSVFPGQP-AIPISQPTFPTSG 469
QS++ + +M+G A ++ GV +P F N P I S PT S
Sbjct: 479 QQSNYNTVSTSMNGYG------SGAMASLGVPGSPGFLNGSSANSPYGIVPSSPTMAASS 532
Query: 470 LTQPQN 487
+T P N
Sbjct: 533 VTLPSN 538
>sp|Q14686|NCOA6_HUMAN Nuclear receptor coactivator 6 (Amplified in breast cancer-3
protein) (Cancer-amplified transcriptional coactivator
ASC-2) (Activating signal cointegrator-2) (ASC-2)
(Peroxisome proliferator-activated receptor-interacting
protein) (PPAR-interacting protein) (PRIP) (Nuclear
receptor-activating protein, 250 kDa) (Nuclear receptor
coactivator RAP250) (NRC RAP250) (Thyroid hormone
receptor-binding protein)
Length = 2063
Score = 30.8 bits (68), Expect = 2.9
Identities = 33/119 (27%), Positives = 41/119 (34%), Gaps = 30/119 (25%)
Frame = +2
Query: 230 GQMPNST--TWPNAGAPAYQSNLMQSDFQSQGYAMSGNNWMV---PGQMNANSAFGVQHN 394
GQ+P++T T N+GAP Q+N QG N V P M S G+ N
Sbjct: 531 GQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGN 590
Query: 395 -----------PFFNNSVFPGQP--------------AIPISQPTFPTSGLTQPQNPML 496
P N S GQP +P G PQNPM+
Sbjct: 591 MNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMI 649
>sp|P83509|GRLF1_CANFA Glucocorticoid receptor DNA-binding factor 1 (Rho GAP p190A) (p190-A)
Length = 1500
Score = 30.4 bits (67), Expect = 3.8
Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Frame = +2
Query: 152 PNISGKLDKSSILA---LYNNSSSTMNTMGQMPNSTTWPNAGAPAYQSNLMQS--DFQSQ 316
P +DK +I+ +Y+N++ +T ++ NS P AG+P SNL S D +
Sbjct: 936 PFFKDVVDKKNIIEATHMYDNAAEACSTTEEVFNS---PRAGSPLCNSNLQDSEEDIEPP 992
Query: 317 GYAMSGNNWMVPGQMNANSAFGVQ 388
Y++ + +P +S ++
Sbjct: 993 SYSLFREDTSLPSLSKDHSKLSME 1016
>sp|O60563|CCNT1_HUMAN Cyclin-T1 (Cyclin-T) (CycT1)
Length = 726
Score = 30.0 bits (66), Expect = 4.9
Identities = 30/123 (24%), Positives = 50/123 (40%), Gaps = 8/123 (6%)
Frame = +2
Query: 125 PSVSTSSAIPNISGKLDKSSILALYNNSSSTMNTMGQMP---NSTTWPNAGAPAYQSNLM 295
PS T A+ + K+ KS+ + N S ++ TMGQMP + T+ + P+ ++ +
Sbjct: 576 PSEETGGAVFDHPAKIAKSTKSSSLNFSFPSLPTMGQMPGHSSDTSGLSFSQPSCKTRVP 635
Query: 296 QSDFQSQGYAMSGNNWMVPGQMNANSAFGVQHNPFFNNSVFPGQPAI-----PISQPTFP 460
S +G+N ++ + H+ V P QP P S P
Sbjct: 636 HSKLDKGPTGANGHN--TTQTIDYQDTVNMLHSLLSAQGVQPTQPTAFEFVRPYSDYLNP 693
Query: 461 TSG 469
SG
Sbjct: 694 RSG 696
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,939,504
Number of Sequences: 369166
Number of extensions: 1710972
Number of successful extensions: 4004
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3812
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3998
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4846822695
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)